Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia

GLIA

Volumn 62, Issue 8, 2014, Pages 1284-1298

  Nomaru, Hiroko ^a   Sakumi, Kunihiko ^a   Katogi, Atsuhisa ^a   Ohnishi, Yoshinori N ^a,b   Kajitani, Kosuke ^a,c   Tsuchimoto, Daisuke ^a   Nestler, Eric J ^b   Nakabeppu, Yusaku ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

AP 1 transcription factors; Kainic acid; Neuroinflammation

Indexed keywords

CD68 ANTIGEN; COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; COMPLEMENT COMPONENT C5A RECEPTOR 1; COMPLEMENT COMPONENT C5A RECEPTOR 2; INTERLEUKIN 6; KAINIC ACID; MESSENGER RNA; TRANSCRIPTION FACTOR FOSB; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; AIF1 PROTEIN, MOUSE; AMINO ACID RECEPTOR STIMULATING AGENT; C5AR1 PROTEIN, MOUSE; C5AR2 PROTEIN, MOUSE; CALCIUM BINDING PROTEIN; CD68 PROTEIN, MOUSE; DIFFERENTIATION ANTIGEN; FOSB PROTEIN, MOUSE; INTERLEUKIN-6, MOUSE; LEUKOCYTE ANTIGEN; PROTEIN C FOS; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CELL ACTIVATION; CELL DENSITY; CELL MOTILITY; CELL STRUCTURE; COMPLEMENT ACTIVATION; CONTROLLED STUDY; EXCITOTOXICITY; GENE FUNCTION; GENE IDENTIFICATION; GENE PRODUCT; HIPPOCAMPAL CA3 REGION; HIPPOCAMPAL NEURONAL CULTURE; IMMUNOREACTIVITY; INNATE IMMUNITY; MICROARRAY ANALYSIS; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEIZURE; ALTERNATIVE RNA SPLICING; ANIMAL; ASTROCYTE; C57BL MOUSE; CELL CULTURE; CHEMOTAXIS; DRUG EFFECTS; GENETICS; HIPPOCAMPUS; KNOCKOUT MOUSE; MALE; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ALTERNATIVE SPLICING; ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; ASTROCYTES; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; CHEMOTAXIS; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; INTERLEUKIN-6; KAINIC ACID; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; MICROGLIA; NEURONS; PROTO-ONCOGENE PROTEINS C-FOS; RECEPTOR, ANAPHYLATOXIN C5A; RNA, MESSENGER; SEIZURES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84902345979     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22680     Document Type: Article

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