Selective induction of ΔFosB in the brain after transient forebrain ischemia accompanied by an increased expression of galectin-1, and the implication of ΔFosB and galectin-1 in neuroprotection and neurogenesis

Cell Death and Differentiation

Volumn 12, Issue 8, 2005, Pages 1078-1096

  Kurushima, H ^a,b   Ohno, M ^a   Miura, T ^a   Nakamura, T Y ^c   Horie, H ^d   Kadoya, T ^e   Ooboshi, H ^b   Kitazono, T ^b   Ibayashi, S ^b   Iida, M ^b   Nakabeppu, Yusaku ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^d WASEDA UNIVERSITY   (Japan)

^e KIRIN BREWERY CO LTD   (Japan)

Author keywords

AP 1; Brain ischemia; Galectin 1; Neurogenesis; Neuronal precursor

Indexed keywords

GALECTIN 1; GLIAL FIBRILLARY ACIDIC PROTEIN; NESTIN; TRANSCRIPTION FACTOR DELTA FOSB; TRANSCRIPTION FACTOR FOSB; FOSB PROTEIN, RAT; INTERMEDIATE FILAMENT PROTEIN; NERVE PROTEIN; PROTEIN C FOS; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELL CULTURE; CELL DENSITY; CELL DIVISION; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; CELL TYPE; CONTROLLED STUDY; EMBRYO; FOREBRAIN; GENE EXPRESSION; GENETIC TRANSCRIPTION; IMMUNOREACTIVITY; NERVOUS SYSTEM DEVELOPMENT; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; ADENOVIRUS; ANIMAL; BIOSYNTHESIS; BRAIN; BRAIN CORTEX; CONFOCAL MICROSCOPY; CYTOLOGY; FLUORESCENCE MICROSCOPY; GENETICS; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MOUSE; NERVE CELL; PHYSIOLOGY; RABBIT; SPONTANEOUSLY HYPERTENSIVE RAT; TRANSIENT ISCHEMIC ATTACK;

ADENOVIRIDAE;

ADENOVIRIDAE; ANIMALS; BRAIN; CELLS, CULTURED; CEREBRAL CORTEX; EMBRYO; GALECTIN 1; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT PROTEINS; ISCHEMIC ATTACK, TRANSIENT; MALE; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; NERVE TISSUE PROTEINS; NEURONS; PROTO-ONCOGENE PROTEINS C-FOS; RABBITS; RATS; RATS, INBRED SHR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS;

EID: 23044516204     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401648     Document Type: Article

References (36)

1. Nakabeppu Y, Ryder K and Nathans D (1988) DNA binding activities of three murine Jun proteins: stimulation by Fos. Cell 55: 907-915
2. Chinenov Y and Kerppola TK (2001) Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity. Oncogene 20: 2438-2452
3. Jochum W, Passegué E and Wagner EF (2001) AP-1 in mouse development and tumorigenesis. Oncogene 20: 2401-2412
4. Shaulian E and Karin M (2001) AP-1 in cell proliferation and survival. Oncogene 20: 2390-2400
5. Nakabeppu Y and Nathans D (1991) A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity. Cell 64: 751-759
6. Chen J, Kelz MB, Hope BT, Nakabeppu Y and Nestler EJ (1997) Chronic Fos-related antigens: stable variants of ΔFosB induced in brain by chronic treatments. J. Neurosci. 17: 4933-4941
7. Sabatakos G, Sims NA, Chen J, Aoki K, Kelz MB, Amling M, Bouali Y, Mukhopadhyay K, Ford K, Nestler EJ and Baron R (2000) Overexpression of ΔFosB transcription factor(s) increases bone formation and inhibits adipogenesis. Nat. Med. 6: 985-990
8. Metz R, Kouzarides T and Bravo R (1994) A C-terminal domain in FosB, absent in FosB/SF and Fra-1, which is able to interact with the TATA binding protein, is required for altered cell growth. EMBO J. 13: 3832-3842
9. Dobrazanski P, Noguchi T, Kovary K, Rizzo CA, Lazo PS and Bravo R (1991) Both products of the fosB gene, FosB and its short form, FosB/SF, are transcriptional activators in fibroblasts. Mol. Cell. Biol. 11: 5470-5478
10. Chen J, Zhang Y, Kelz MB, Steffen C, Ang ES, Zeng L and Nestler EJ (2000) Induction of cyclin-dependent kinase 5 in the hippocampus by chronic electroconvulsive seizures: role of ΔFosB. J. Neurosci. 20: 8965-8971
11. McClung CA and Nestler EJ (2003) Regulation of gene expression and cocaine reward by CREB and ΔFosB. Nat. Neurosci. 6: 1208-1215
12. Herdegen T and Leah JD (1998) Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res. Brain Res. Rev. 28: 370-490
13. McGahan L, Hakim AM, Nakabeppu Y and Robertson GS (1998) Ischemia-induced CA1 neuronal death is preceded by elevated FosB and Jun expression and reduced NGFI-A and JunB levels. Mol. Brain Res. 56: 146-161
14. Liu J, Solway K, Messing RO and Sharp FR (1998) Increased neurogenesis in the dentate gyrus after transient global ischemia in gerbils. J. Neurosci. 18: 7768-7778
15. Gage FH (2000) Mammalian neural stem cells. Science 287: 1433-1438
16. Jin K, Minami M, Lan JQ, Mao XO, Batteur S, Simon RP and Greenberg DA (2001) Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat. Proc. Natl. Acad. Sci. USA 98: 4710-4715
17. Nakatomi H, Kuriu T, Okabe S, Yamamoto S, Hatano O, Kawahara N, Tamura A, Kirino T and Nakafuku M (2002) Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors. Cell 110: 429-441
18. Nakabeppu Y, Oda S and Sekiguchi M (1993) Proliferative activation of quiescent Rat-1A cells by ΔFosB. Mol. Cell. Biol. 13: 4157-4166
19. Oda S, Nishida J, Nakabeppu Y and Sekiguchi M (1995) Stabilization of cyclin E and cdk2 mRNAs at G1/S transition in Rat-1A cells emerging from the G0 state. Oncogene 10: 1343-1351
20. Nishioka T, Sakumi K, Miura T, Tahara K, Horie H, Kadoya T and Nakabeppu Y (2002) fosB gene products trigger cell proliferation and morphological alteration with an increased expression of a novel processed form of galectin-1 in the rat 3Y1 embryo cell line. J. Biochem. 131: 653-661
21. Tahara K, Tsuchimoto D, Tominaga Y, Asoh S, Ohta S, Kitagawa M, Horie H, Kadoya T and Nakabeppu Y (2003) ΔFosB, but not FosB, induces delayed apoptosis independent of cell proliferation in the Rat1a embryo cell Line. Cell Death Differ. 10: 496-507
22. Miura T, Takahashi M, Horie H, Kurushima H, Tsuchimoto D, Sakumi K and Nakabeppu Y (2004) Galectin-1β, a natural monomeric form of galectin-1 lacking its six amino-terminal residues promotes axonal regeneration but not cell death. Cell Death Differ. 11: 1076-1083
23. Yao H, Sadoshima S, Ooboshi H, Sato Y, Uchimura H and Fujishima M (1991) Age-related vulnerability to cerebral ischemia in spontaneously hypertensive rats. Stroke 22: 1414-1418
24. Hotta Y, Honda T, Naito M and Kuwano R (2003) Developmental distribution of coxsackie virus and adenovirus receptor localized in the nervous system. Brain Res. Dev. Brain Res. 143: 1-13
25. Sato Y, Shiraishi Y and Furuichi T (2004) Cell specificity and efficiency of the Semliki forest virus vector- and adenovirus vector-mediated gene expression in mouse cerebellum. J. Neurosci. Methods 137: 111-121
26. Brewer GJ (1995) Serum-free B27/Neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus. J. Neurosci. Res. 42: 674-683
27. Cheng A, Wang S, Yang D, Xiao R and Mattson MP (2003) Calmodulin mediates brain-derived neurotrophic factor cell survival signaling upstream of Akt kinase in embryonic neocortical neurons. J. Biol. Chem. 278: 7591-7599
28. Herdegen T, Claret FX, Kallunki T, Martin-Villalba A, Winter C, Hunter T and Karin M (1998) Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury. J. Neurosci. 18: 5124-5135
29. Herdegen T and Waetzig V (2001) AP-1 proteins in the adult brain: facts and fiction about effectors of neuroprotection and neurodegeneration. Oncogene 20: 2424-2437
30. Doetsch F, Garcîa-Verdugo JM and Alvarez-Buylla A (1997) Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J. Neurosci. 17: 5046-5061
31. Fukuda S, Kato F, Tozuka Y, Yamaguchi M, Miyamoto Y and Hisatsune T (2003) Two distinct subpopulations of nestin-positive cells in adult mouse dentate gyrus. J. Neurosci. 23: 9357-9366
32. Garcia AD, Doan NB, Imura T, Bush TG and Sofroniew MV (2004) GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain. Nat. Neurosci. 7: 1233-1241
33. Nakabeppu Y and Nathans D (1989) The basic region of Fos mediates specific DNA binding. EMBO J. 8: 3833-3841
34. Murphy TH, Worley PF, Nakabeppu Y, Christy B, Gastel J and Baraban JM (1991) Synaptic regulation of immediate early gene expression in primary cultures of cortical neurons. J. Neurochem. 57: 1862-1872
35. Horie H, Inagaki Y, Sohma Y, Nozawa R, Okawa K, Hasegawa M, Muramatsu N, Kawano H, Horie M, Koyama H, Sakai I, Takeshita K, Kowada Y, Takano M and Kadoya T (1999) Galectin-1 regulates initial axonal growth in peripheral nerves after axotomy. J. Neurosci. 19: 9964-9974
36. Smith ML, Bendek G, Dahlgren N, Rosén I, Wieloch T and Siesjö BK (1984) Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model. Acta Neurol. Scand. 69: 385-401