Structural basis for the inhibition of host protein ubiquitination by shigella effector kinase OspG

Structure

Volumn 22, Issue 6, 2014, Pages 878-888

  Grishin, Andrey M ^a   Condos, Tara E C ^b   Barber, Kathryn R ^b   Campbell Valois, François Xavier ^c,d   Parsot, Claude ^c,d   Shaw, Gary S ^b   Cygler, Miroslaw ^a,e  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c INSTITUT PASTEUR   (France)

^d INSERM   (France)

^e MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; PARKIN; PROTEASOME; PROTEIN KINASE; PROTEIN KINASE OSPG; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN CONJUGATING ENZYME UBCH7; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MULTIPROTEIN COMPLEX; UBE2L3 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

ALPHA HELIX; ARTICLE; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STRUCTURE; SHIGELLA; SIGNAL TRANSDUCTION; TYPE III SECRETION SYSTEM; UBIQUITINATION; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HOST PATHOGEN INTERACTION; HUMAN; METABOLISM; PATHOGENICITY; PHYSIOLOGY; PROTEIN DOMAIN; SHIGELLA FLEXNERI; X RAY CRYSTALLOGRAPHY;

SHIGELLA;

ADENOSINE TRIPHOSPHATE; BACTERIAL PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HOST-PATHOGEN INTERACTIONS; HUMANS; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; NF-KAPPA B; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEOLYSIS; SHIGELLA FLEXNERI; SIGNAL TRANSDUCTION; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84902332058     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2014.04.010     Document Type: Article

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