메뉴 건너뛰기




Volumn 3, Issue 4, 2014, Pages 408-418

Mitochondrial dysfunction has divergent, cell type-dependent effects on insulin action

Author keywords

Adipocyte; Hepatocyte; Insulin action; Mitochondria; Reactive oxygen species

Indexed keywords

INSULIN; ISOPHANE INSULIN; LACTATE DEHYDROGENASE; OLIGOMYCIN; PHENFORMIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REACTIVE OXYGEN METABOLITE; ROSIGLITAZONE; ROTENONE;

EID: 84902313581     PISSN: 22128778     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molmet.2014.02.001     Document Type: Article
Times cited : (44)

References (37)
  • 1
    • 84874045511 scopus 로고    scopus 로고
    • Origins and drivers of insulin resistance
    • Johnson D.A., Olefsky J.M. Origins and drivers of insulin resistance. Cell 2013, 152:673-684.
    • (2013) Cell , vol.152 , pp. 673-684
    • Johnson, D.A.1    Olefsky, J.M.2
  • 2
    • 79953180902 scopus 로고    scopus 로고
    • Assessing mitochondrial dysfunction in cells
    • Brand M.D., Nicholls D.G. Assessing mitochondrial dysfunction in cells. Biochemical Journal 2011, 435:297-312.
    • (2011) Biochemical Journal , vol.435 , pp. 297-312
    • Brand, M.D.1    Nicholls, D.G.2
  • 3
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
    • Kelley D.E., He J., Menshikova E.V., Ritov V.B. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 2002, 51:2944-2950.
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 4
    • 58149346025 scopus 로고    scopus 로고
    • Lower intrinsic ADP-stimulated mitochondrial respiration underlies invivo mitochondrial dysfunction in muscle of male type 2 diabetic patients
    • Phielix E., Schrauwen-Hinderling V.B., Mensink M., Lenaers E., Meex R., Hoeks J., et al. Lower intrinsic ADP-stimulated mitochondrial respiration underlies invivo mitochondrial dysfunction in muscle of male type 2 diabetic patients. Diabetes 2005, 57:2943-2949.
    • (2005) Diabetes , vol.57 , pp. 2943-2949
    • Phielix, E.1    Schrauwen-Hinderling, V.B.2    Mensink, M.3    Lenaers, E.4    Meex, R.5    Hoeks, J.6
  • 8
    • 79951697487 scopus 로고    scopus 로고
    • Liver ATP synthesis is lower and relates to insulin sensitivity in patients with type 2 diabetes
    • Schmid A.I., Szendroedi J., Chmelik M., Krššak M., Moser E., Roden M. Liver ATP synthesis is lower and relates to insulin sensitivity in patients with type 2 diabetes. Diabetes Care 2011, 34:448-453.
    • (2011) Diabetes Care , vol.34 , pp. 448-453
    • Schmid, A.I.1    Szendroedi, J.2    Chmelik, M.3    Krššak, M.4    Moser, E.5    Roden, M.6
  • 10
    • 17844385363 scopus 로고    scopus 로고
    • Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue invivo
    • Bogacka I., Xie H., Bray G.A., Smith S.R. Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue invivo. Diabetes 2005, 54:1392-1399.
    • (2005) Diabetes , vol.54 , pp. 1392-1399
    • Bogacka, I.1    Xie, H.2    Bray, G.A.3    Smith, S.R.4
  • 11
    • 33644821858 scopus 로고    scopus 로고
    • Mitochondria are impaired in the adipocytes of type 2 diabetic mice
    • Choo H.J., Kim J.H., Kwon O.B., Lee C.S., Mun J.Y., Han S.S., et al. Mitochondria are impaired in the adipocytes of type 2 diabetic mice. Diabetologia 2006, 49:784-791.
    • (2006) Diabetologia , vol.49 , pp. 784-791
    • Choo, H.J.1    Kim, J.H.2    Kwon, O.B.3    Lee, C.S.4    Mun, J.Y.5    Han, S.S.6
  • 13
  • 14
    • 0026462744 scopus 로고
    • Diabetes mellitus associated with a pathogenic point mutation in mitochondrial DNA
    • Reardon W., Ross R.J., Sweeney M.G., Luxon L.M., Pembrey M.E., Harding A.E., et al. Diabetes mellitus associated with a pathogenic point mutation in mitochondrial DNA. Lancet 1992, 340:1376-1379.
    • (1992) Lancet , vol.340 , pp. 1376-1379
    • Reardon, W.1    Ross, R.J.2    Sweeney, M.G.3    Luxon, L.M.4    Pembrey, M.E.5    Harding, A.E.6
  • 16
    • 65349196063 scopus 로고    scopus 로고
    • Impaired mitochondrial function and insulin resistance of skeletal muscle in mitochondrial diabetes
    • Szendroedi J., Schmid A.I., Meyerspeer M., Cervin C., Kacerovsky M., Smekal G., et al. Impaired mitochondrial function and insulin resistance of skeletal muscle in mitochondrial diabetes. Diabetes Care 2009, 32:677-679.
    • (2009) Diabetes Care , vol.32 , pp. 677-679
    • Szendroedi, J.1    Schmid, A.I.2    Meyerspeer, M.3    Cervin, C.4    Kacerovsky, M.5    Smekal, G.6
  • 17
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and type 2 diabetes
    • Lowell B.B., Shulman G.I. Mitochondrial dysfunction and type 2 diabetes. Science 2005, 307:384-387.
    • (2005) Science , vol.307 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2
  • 18
    • 31044433308 scopus 로고    scopus 로고
    • Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents
    • Morino K., Petersen K.F., Dufour S., Befroy D., Frattini J., Shatzkes N., et al. Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents. Journal of Clinical Investigation 2005, 115:3587-3593.
    • (2005) Journal of Clinical Investigation , vol.115 , pp. 3587-3593
    • Morino, K.1    Petersen, K.F.2    Dufour, S.3    Befroy, D.4    Frattini, J.5    Shatzkes, N.6
  • 21
    • 79955930100 scopus 로고    scopus 로고
    • Deficiency of the mitochondrial electron transport chain in muscle does not cause insulin resistance
    • Han D.H., Hancock C.R., Jung S.R., Higashida K., Kim S.H., Holloszy J.O. Deficiency of the mitochondrial electron transport chain in muscle does not cause insulin resistance. PLoS One 2011, 6:e19739.
    • (2011) PLoS One , vol.6
    • Han, D.H.1    Hancock, C.R.2    Jung, S.R.3    Higashida, K.4    Kim, S.H.5    Holloszy, J.O.6
  • 22
    • 35548999739 scopus 로고    scopus 로고
    • Targeted deletion of AIF decreases mitochondrial oxidativephosphorylation and protects from obesity and diabetes
    • Pospisilik J.A., Knauf C., Joza N., Benit P., Orthofer M., Cani P.D., et al. Targeted deletion of AIF decreases mitochondrial oxidativephosphorylation and protects from obesity and diabetes. Cell 2007, 131:476-491.
    • (2007) Cell , vol.131 , pp. 476-491
    • Pospisilik, J.A.1    Knauf, C.2    Joza, N.3    Benit, P.4    Orthofer, M.5    Cani, P.D.6
  • 23
    • 84874511732 scopus 로고    scopus 로고
    • Mice deficient in the respiratory chain gene Cox6a2 are protected against high-fat diet-induced obesity and insulin resistance
    • Quintens R., Singh S., Lemaire K., De Bock K., Granvik M., Schraenen A., et al. Mice deficient in the respiratory chain gene Cox6a2 are protected against high-fat diet-induced obesity and insulin resistance. PLoS One 2013, 8:e56719.
    • (2013) PLoS One , vol.8
    • Quintens, R.1    Singh, S.2    Lemaire, K.3    De Bock, K.4    Granvik, M.5    Schraenen, A.6
  • 24
    • 0034659785 scopus 로고    scopus 로고
    • Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
    • Owen M.R., Doran E., Halestrap A.P. Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochemical Journal 2000, 348:607-614.
    • (2000) Biochemical Journal , vol.348 , pp. 607-614
    • Owen, M.R.1    Doran, E.2    Halestrap, A.P.3
  • 28
    • 0016148014 scopus 로고
    • Characterisation of differentiated and dedifferentiated clones from a rat hepatoma
    • Deschatrette J., Weiss M.C. Characterisation of differentiated and dedifferentiated clones from a rat hepatoma. Biochimie 1974, 56:1603-1611.
    • (1974) Biochimie , vol.56 , pp. 1603-1611
    • Deschatrette, J.1    Weiss, M.C.2
  • 30
    • 33644746318 scopus 로고    scopus 로고
    • Increased lipid availability impairs insulin-stimulated ATP synthesis in human skeletal muscle
    • Brehm A., Krssak M., Schmid A.I., Nowotny P., Waldhausl W., Roden M. Increased lipid availability impairs insulin-stimulated ATP synthesis in human skeletal muscle. Diabetes 2006, 55:136-140.
    • (2006) Diabetes , vol.55 , pp. 136-140
    • Brehm, A.1    Krssak, M.2    Schmid, A.I.3    Nowotny, P.4    Waldhausl, W.5    Roden, M.6
  • 31
    • 77956367951 scopus 로고    scopus 로고
    • Prolonged fasting identifies skeletal muscle mitochondrial dysfunction as consequence rather than cause of human insulin resistance
    • Hoeks J., van Herpen N.A., Mensink M., Moonen-Kornips E., van Beurden D., Hesselink M.K., et al. Prolonged fasting identifies skeletal muscle mitochondrial dysfunction as consequence rather than cause of human insulin resistance. Diabetes 2010, 59:2117-2125.
    • (2010) Diabetes , vol.59 , pp. 2117-2125
    • Hoeks, J.1    van Herpen, N.A.2    Mensink, M.3    Moonen-Kornips, E.4    van Beurden, D.5    Hesselink, M.K.6
  • 32
    • 33645860825 scopus 로고    scopus 로고
    • Reactive oxygen species have a causal role in multiple forms of insulin resistance
    • Houstis N., Rosen E.D., Lander E.S. Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature 2006, 440:944-948.
    • (2006) Nature , vol.440 , pp. 944-948
    • Houstis, N.1    Rosen, E.D.2    Lander, E.S.3
  • 34
    • 54849439728 scopus 로고    scopus 로고
    • CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes
    • Yip M.F., Ramm G., Larance M., Hoehn K.L., Wagner M.C., Guilhaus M., et al. CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes. Cell Metabolism 2008, 8:384-398.
    • (2008) Cell Metabolism , vol.8 , pp. 384-398
    • Yip, M.F.1    Ramm, G.2    Larance, M.3    Hoehn, K.L.4    Wagner, M.C.5    Guilhaus, M.6
  • 35
    • 84873707522 scopus 로고    scopus 로고
    • Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP
    • Miller R.A., Chu Q., Xie J., Foretz M., Viollet B., Birnbaum M.J. Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP. Nature 2013, 494:256-260.
    • (2013) Nature , vol.494 , pp. 256-260
    • Miller, R.A.1    Chu, Q.2    Xie, J.3    Foretz, M.4    Viollet, B.5    Birnbaum, M.J.6
  • 36
    • 77954933558 scopus 로고    scopus 로고
    • Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
    • Foretz M., Hébrard S., Leclerc J., Zarrinpashneh E., Soty M., Mithieux G., et al. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state. Journal of Clinical Investigation 2010, 120:2355-2369.
    • (2010) Journal of Clinical Investigation , vol.120 , pp. 2355-2369
    • Foretz, M.1    Hébrard, S.2    Leclerc, J.3    Zarrinpashneh, E.4    Soty, M.5    Mithieux, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.