Validation of genome-wide association study (GWAS)-identified disease risk alleles with patient-specific stem cell lines

Human Molecular Genetics

Volumn 23, Issue 13, 2014, Pages 3445-3455

  Yang, Jin ^a,b,c   Li, Yao ^a,b   Chan, Lawrence ^a,b   Tsai, Yi Ting ^a,b   Wu, Wen Hsuan ^a,b   Nguyen, Huy V ^a,b   Hsu, Chun Wei ^a,b   Li, Xiaorong ^c   Brown, Lewis M ^d   Egli, Dieter ^e   Sparrow, Janet R ^b   Tsang, Stephen H ^a,b,f  

^a Barbara and Donald Jonas Laboratory of Stem Cells and Regenerative Medicine Department of Ophthalmology Pathology and Cell Biology College of Physicians and Surgeons Columbia University ^*  (United States)

^b New York Presbyterian Hospital   (United States)

^c TIANJIN MEDICAL UNIVERSITY   (China)

^d Och Spine at New York Presbyterian Hospitals   (United States)

^e New York Stem Cell Foundation Laboratory   (United States)

^f NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MANGANESE SUPEROXIDE DISMUTASE;

ALLELE; ARMS2 GENE; ARTICLE; ATROPHY; AUTOPSY; CHROMOSOME 10Q; CONTROLLED STUDY; FIBROSIS; GENE; GENE LOCATION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HAPLOTYPE; HEALTH CARE FACILITY; HOMOZYGOTE; HTRA1 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; INDEL MUTATION; OXIDATIVE STRESS; PATHOGENESIS; PIGMENT EPITHELIUM; PLURIPOTENT STEM CELL; POPULATION GENETICS; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; RISK ASSESSMENT; STEM CELL LINE; VALIDATION PROCESS; CELL LINE; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; PROCEDURES;

ALLELES; CELL LINE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HAPLOTYPES; HUMANS;

EID: 84902302801     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu053     Document Type: Article

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