SEM/EDX and confocal Raman microscopy as complementary tools for the characterization of pharmaceutical tablets

International Journal of Pharmaceutics

Volumn 470, Issue 1-2, 2014, Pages 88-98

  Scoutaris, Nikolaos ^a   Vithani, Kapilkumar ^a   Slipper, Ian ^a   Chowdhry, Babur ^a   Douroumis, Dennis ^a  

^a UNIVERSITY OF GREENWICH   (United Kingdom)

Author keywords

Confocal Raman; Energy dispersive X ray spectroscopy; Homogeneity; Hot melt extrusion

Indexed keywords

EXCIPIENT; GLYCEROL BEHENATE; NITROGEN; PARACETAMOL; SORBITOL; FATTY ACID; TABLET;

ARTICLE; CONFOCAL MICROSCOPY; DRUG ANALYSIS; ENERGY DISPERSIVE X RAY SPECTROSCOPY; PRIORITY JOURNAL; RAMAN SPECTROMETRY; ROOM TEMPERATURE; SCANNING ELECTRON MICROSCOPY; TABLET FORMULATION; TABLET SURFACE; TEMPERATURE; CHEMISTRY; MULTIVARIATE ANALYSIS; PHARMACEUTICS; PROCEDURES; SPECTROMETRY; TABLET;

ACETAMINOPHEN; FATTY ACIDS; MICROSCOPY, ELECTRON, SCANNING; MULTIVARIATE ANALYSIS; SPECTROMETRY, X-RAY EMISSION; SPECTRUM ANALYSIS, RAMAN; TABLETS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84902288090     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.05.007     Document Type: Article

References (39)

1. O.A. Al-Fulaij, A.-Z.A. Elassar, and A. El-Dissouky Synthesis, characterization, and ligating behavior of poly[N,N-p-phenylene bisacryl (methacryl)amide] J. Appl. Polym. Sci. 101 2006 2412 2422 (Pubitemid 44117499)
2. D.M. Charron, K. Ajito, J.-Y. Kim, and Y. Ueno Chemical mapping of pharmaceutical cocrystals using terahertz spectroscopic imaging Anal. Chem. 85 2013 1980 1984
3. H. Chen, V.H. Grassian, L.V. Saraf, and A. Laskin Chemical imaging analysis of environmental particles using the focused ion beam/scanning electron microscopy technique: microanalysis insights into atmospheric chemistry of fly ash Analyst 138 2013 451 460
4. R. Chen, Z. Zhang, Z. Lei, and N. Sugiura Preparation of iron-impregnated tablet ceramic adsorbent for arsenate removal from aqueous solutions Desalination 286 2012 56 62
5. A. Domenech-Carbo, M.A.T. Domenech-Carbo, J.V. Gimeno-Adelantado, F. Bosch-Reig, M.A.C. Sauri-Peris, and S. Sanchez-Ramos Electrochemistry of iron oxide pigments (earths) from pictorial microsamples attached to graphite-polyester composite electrodes Analyst 126 2001 1764 1772 (Pubitemid 33015946)
6. P.H.C. Eilers A perfect smoother Anal. Chem. 75 2003 3631 3636 (Pubitemid 36871257)
7. M. Fransson, J. Johansson, A. Sparén, and O. Svensson Comparison of multivariate methods for quantitative determination with transmission Raman spectroscopy in pharmaceutical formulations J. Chemom. 24 2010 674 680
8. 2/electroreduced graphene oxide-multiwalled carbon nanotube film modified glass carbon electrode Talanta 120 2014 484 490
9. C. Gendrin, Y. Roggo, and C. Collet Pharmaceutical applications of vibrational chemical imaging and chemometrics: a review J. Pharm. Biom. Anal. 48 2008 533 553
10. K.C. Gordon, and C.M. McGoverin Raman mapping of pharmaceuticals Int. J. Pharm. 417 2011 151 162
11. M. Haaser, M. Windbergs, C.M. McGoverin, P. Kleinebudde, T. Rades, K.C. Gordon, and C.J. Strachan Analysis of matrix dosage forms during dissolution testing using raman microscopy J. Pharm. Sci. 100 2011 4452 4459
12. V. Iannuccelli, G. Coppi, M. Romagnoli, S. Sergi, and E. Leo In vivo detection of lipid-based nano- and microparticles in the outermost human stratum corneum by EDX analysis Int. J. Pharm. 447 2013 204 212
13. S.J. Inman, B.J. Briscoe, and K.G. Pitt Topographic characterization of cellulose bilayered tablets interfaces Chem. Eng. Res. Des. 85 2007 1005 1012 (Pubitemid 47241495)
14. J. Goldstein, D.E. Newbury, P. Echlin, D.C. Joy, C.E. Lyman, E. Lifshin, L. Linda Sawyer, and J.R. Michael Scanning Electron Microscopy and X-ray Microanalysis 2003 Plenum Press
15. E. Katainen, M. Elomaa, U.-M. Laakkonen, E. Sippola, P. Niemelä, J. Suhonen, and K. Järvinen Quantification of the amphetamine content in seized street samples by Raman spectroscopy J. Forensic Sci. 52 2007 88 92 (Pubitemid 46018426)
16. F. Liu, R. Lizio, U.J. Schneider, H.-U. Petereit, P. Blakey, and A.W. Basit SEM/EDX and confocal microscopy analysis of novel and conventional enteric-coated systems Int. J. Pharm. 369 2009 72 78
17. M. Maniruzzaman, J.S. Boateng, M. Bonnefille, A. Aranyos, J.C. Mitchell, and D. Douroumis Taste masking of paracetamol by hot-melt extrusion: an in vitro and in vivo evaluation Eur. J. Pharm. Biopharm. 80 2012 433 442
18. M. Maniruzzaman, J.S. Boateng, M.J. Snowden, and D. Douroumis A review of hot-melt extrusion: process technology to pharmaceutical products ISRN Pharm. 2012 9
19. S. Mazurek, and R. Szostak Quantitative determination of captopril and prednisolone in tablets by FT-Raman spectroscopy J. Pharm. Biomed. Anal. 40 2006 1225 1230 (Pubitemid 43247462)
20. S. Mazurek, and R. Szostak Quantification of atorvastatin calcium in tablets by FT-Raman spectroscopy J. Pharm. Biom. Anal. 49 2009 168 172
21. N. Mohammed, S. Majumdar, A. Singh, W. Deng, N. Murthy, E. Pinto, D. Tewari, T. Durig, and M. Repka Klucel™ EF and ELF polymers for immediate-release oral dosage forms prepared by melt extrusion technology AAPS PharmSciTech 13 2012 1158 1169
22. K. Nakamoto, T. Urasaki, S. Hondo, N. Murahashi, E. Yonemochi, and K. Terada Evaluation of the crystalline and amorphous states of drug products by nanothermal analysis and Raman imaging J. Pharm. Biom. Anal. 75 2013 105 111
23. A. Naranjo, M.P. Noriega, T. Osswald, Roldan-Alzate, and A.J.D. Sierra Plastic Testing and Characterisation 2008 Gardner Publication Hanser Inc.
24. 2 coatings on titanium alloys using a hybrid technique of micro-arc oxidation and electrophoresis Surf. Coat. Technol. 125 2000 407 414 (Pubitemid 30233940)
25. C.W. Pouton Formulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification system Eur. J. Pharm. Sci. 29 2006 278 287 (Pubitemid 44740131)
26. E. Roblegg, E. Jäger, A. Hodzic, G. Koscher, S. Mohr, A. Zimmer, and J. Khinast Development of sustained-release lipophilic calcium stearate pellets via hot melt extrusion Eur. J. Pharm. Biopharm. 79 2011 635 645
27. S. Šašić Raman mapping of low-content api pharmaceutical formulations. I. Mapping of alprazolam in alprazolam/xanax tablets Pharm. Res. 24 2007 58 65 (Pubitemid 44902570)
28. W. Sinclair, M. Leane, G. Clarke, A. Dennis, M. Tobyn, and P. Timmins Physical stability and recrystallization kinetics of amorphous ibipinabant drug product by fourier transform raman spectroscopy J. Pharm. Sci. 100 2011 4687 4699
29. C.J. Strachan, T. Rades, K.C. Gordon, and J. Rantanen Raman spectroscopy for quantitative analysis of pharmaceutical solids J. Pharm. Pharmacol. 59 2007 179 192 (Pubitemid 46203057)
30. H. Ueda, Y. Ida, K. Kadota, and Y. Tozuka Raman mapping for kinetic analysis of crystallization of amorphous drug based on distributional images Int. J. Pharm. 462 2014 115 122
31. B. Vajna, I. Farkas, A. Farkas, H. Pataki, Z. Nagy, J. Madarász, and G. Marosi Characterization of drug-cyclodextrin formulations using Raman mapping and multivariate curve resolution J. Pharm. Biomed. Anal. 56 2011 38 44
32. B. Vajna, H. Pataki, Z. Nagy, I. Farkas, and G. Marosi Characterization of melt extruded and conventional Isoptin formulations using Raman chemical imaging and chemometrics Int. J. Pharm. 419 2011 107 113
33. V. Venkateswarlu, and K. Manjunath Preparation, characterization and in vitro release kinetics of clozapine solid lipid nanoparticles J. Control. Rel. 95 2004 627 638 (Pubitemid 38344153)
34. T. Vilhelmsen, H. Eliasen, and T. Schæfer Effect of a melt agglomeration process on agglomerates containing solid dispersions Int. J. Pharm. 303 2005 132 142 (Pubitemid 41318030)
35. K. Vithani, Y. Cuppok, S. Mostafa, I.J. Slipper, M.J. Snowden, and D. Douroumis Diclofenac sodium sustained release hot melt extruded lipid matrices Pharm. Dev. Technol. 19 2014 531 538
36. A.K. Vynckier, L. Dierickx, L. Saerens, J. Voorspoels, Y. Gonnissen, T. De Beer, C. Vervaet, and J.P. Remon Hot-melt co-extrusion for the production of fixed-dose combination products with a controlled release ethylcellulose matrix core Int. J. Pharm. 464 2014 65 74
37. J.-H. Wang, P.K. Hopke, T.M. Hancewicz, and S.L. Zhang Application of modified alternating least squares regression to spectroscopic image analysis Anal. Chim. Acta 476 2003 93 109 (Pubitemid 35441147)
38. E. Widjaja, P. Kanaujia, G. Lau, W.K. Ng, M. Garland, C. Saal, A. Hanefeld, M. Fischbach, M. Maio, and R.B.H. Tan Detection of trace crystallinity in an amorphous system using Raman microscopy and chemometric analysis Eur. J. Pharm. Sci. 42 2011 45 54
39. L. Zhang, M.J. Henson, and S.S. Sekulic Multivariate data analysis for Raman imaging of a model pharmaceutical tablet Anal. Chim. Acta 545 2005 262 278 (Pubitemid 40898281)