Hot-melt co-extrusion for the production of fixed-dose combination products with a controlled release ethylcellulose matrix core

International Journal of Pharmaceutics

Volumn 464, Issue 1-2, 2014, Pages 65-74

  Vynckier, A K ^a   Dierickx, L ^a   Saerens, L ^a   Voorspoels, J ^b   Gonnissen, Y ^b   De Beer, T ^a   Vervaet, C ^a   Remon, J P ^a  

^a GHENT UNIVERSITY   (Belgium)

^b Ghent University ^*  (Belgium)

Author keywords

Co extrusion; Fixed dose combination product; Hot melt extrusion; Immediate release; Matrix; Sustained release

Indexed keywords

CO-EXTRUSION; FIXED-DOSE COMBINATION PRODUCT; HOT-MELT EXTRUSION; HYDROCHLOROTHIAZIDE (PUBCHEM CID: 3639); IMMEDIATE RELEASE; MATRIX; METOPROLOL TARTRATE (PUBCHEM CID: 441308); SUSTAINED RELEASE;

ANIMALS; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DOGS; DRUG COMBINATIONS; HOT TEMPERATURE; MALE;

EID: 84894063589     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.01.028     Document Type: Article

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