Evaluation of the crystalline and amorphous states of drug products by nanothermal analysis and Raman imaging

Journal of Pharmaceutical and Biomedical Analysis

Volumn 75, Issue , 2013, Pages 105-111

  Nakamoto, Keizo ^a,b,c   Urasaki, Tetsuhiko ^a   Hondo, Satoko ^a   Murahashi, Naokazu ^a   Yonemochi, Etsuo ^b,c   Terada, Katuhide ^b,c  

^a EISAI CO LTD   (Japan)

^b TOHO UNIVERSITY   (Japan)

^c PAT Committee   (Japan)

Author keywords

Amorphous; Crystallization; Drug product; Nanothermal analysis; Process analytical technology; Raman spectroscopy

Indexed keywords

CRYSTALLIN;

ARTICLE; CHEMICAL COMPOSITION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; INTERMETHOD COMPARISON; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAMAN SPECTROMETRY; TABLET; THERMAL ANALYSIS;

CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DIFFERENTIAL THERMAL ANALYSIS; EXCIPIENTS; JAPAN; MOLECULAR CONFORMATION; PHARMACEUTICAL PREPARATIONS; PHYSICOCHEMICAL PHENOMENA; POWDER DIFFRACTION; QUALITY CONTROL; SPECTRUM ANALYSIS, RAMAN; TABLETS;

EID: 84871799403     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.11.020     Document Type: Article

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