Topographic characterization of cellulose bilayered tablets interfaces

Chemical Engineering Research and Design

Volumn 85, Issue 7 A, 2007, Pages 1005-1012

  Inman, Sharon J ^a   Briscoe, B J ^a   Pitt, K G ^b,c  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b Merck Sharp & Dohme Limited   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Bilayer tablets; Fracture strength; Microcrystalline cellulose; Profilometry

Indexed keywords

CRACKS; FRACTURE TOUGHNESS; INTERFACES (MATERIALS); PROFILOMETRY; STRESS CONCENTRATION; SURFACE TOPOGRAPHY; TENSILE STRESS;

BILAYER TABLETS; MICROCRYSTALLINE CELLULOSE;

DRUG PRODUCTS;

CRACKS; DRUG PRODUCTS; FRACTURE TOUGHNESS; INTERFACES (MATERIALS); PROFILOMETRY; STRESS CONCENTRATION; SURFACE TOPOGRAPHY; TENSILE STRESS;

EID: 34547733037     PISSN: 02638762     EISSN: None     Source Type: Journal    
DOI: 10.1205/cherd06188     Document Type: Article

References (50)

1. Abdul, S. and Poddar, S.S., 2004, A flexible technology for modified release of drugs: multi layered tablets, Journal of Controlled Release, 97(3): 393-405.
2. Aydin, I., Biglari, F.R., Briscoe, B.J., Lawrence, C.J. and Adams, M.J., 2000, Physical and numerical modelling of ram extrusion of paste materials: conical die entry case, Computational Materials Science, 18(2): 141-155.
3. Bashaiwoldu, A.B., Podczeck, F. and Newton, J.M., (2004a), The application of non-contact laser profilometry to the determination of permanent structural change induced by compaction of pellets: II. Pellets dried by different techniques, European Journal of Pharmaceutical Sciences, 22(1): 55-61.
4. Bashaiwoldu, A.B., Podczeck, F. and Newton, J.M., (2004b), The application of non-contact laser profilometry to the determination of permanent structural changes induced by compaction of pellets: I. Pellets of different composition, European Journal of Pharmaceutical Sciences, 21(2-3): 143-154.
5. Brooks, R.A. and Di Chiro, G., 1976, Beam hardening in X-ray reconstructive tomography, Physics in Medicine and Biology, 21(3): 390-398.
6. Cazaux, J., El, Hila, H., Erre, D., Mouze, D., Pata, J.M., Rondot, S., Trebbia, P. and Zolfaghari, A., 1994, Progress in X-ray projection microscopy, Microsc. Anal., May: 17-19.
7. De Man, B., Nuyts, J., Dupont, P., Marchal, G. and Suetens, P., 2001, An iterative maximum-likelihood polychromatic algorithm for CT, IEEE Transactions on Medical Imaging, 20(10).
8. Eiliazadeh, B., 2004, Influences of Punch Geometry on Powder Tabletting Processes, In PhD Thesis Imperial College, London.
9. Eiliazadeh, B., Pitt, K. and Briscoe, B., 2004, Effects of punch geometry on powder movement during pharmaceutical tabletting processes, International Journal of Solids and Structures, 41(21): 5967-5977.
10. Gong, G., Xie, B.-H., Yang, W., Li, Z.-M., Zhang, W.-Q. and Yang, M.-B., 2005, Essential work of fracture (EWF) analysis for polypropylene grafted with maleic anhydride modified polypropylene/calcium carbonate composites, Polymer Testing, 24(4): 410-417.
11. Griffith, A.A., 1920, The phenomena of rupture and flow in solids, Transactions of the Royal Society, A221: 163-198.
12. Hammersberg, P. and Mangard, M., 1998, Correction for beam hardening artefacts in computerised tomography, Journal of X-Ray Science and Technology, 8(1): 75-93.
13. Hancock, B.C., Clas, S.D. and Christensen, K., 2000, Micro-scale measurement of the mechanical properties of compressed pharmaceutical powders. 1: The elasticity and fracture behaviour of microcrystalline cellulose, Int J Pharm, 209(1-2): 27-35.
14. Herman, G.T., 1979, Correction for beam hardening in computed tomography, Physics in Medicine and Biology, 24(1): 81-106.
15. Holzgrabe, U., 1998, NMR spectroscopy in pharmacy, Journal of Pharmaceutical and Biomedical Analysis, 17(4-5): 557-616.
16. Inman, S.J., Briscoe, B.J. and Pitt, K.G., 2006, In Determination of the Critical Stress Intensity Factor (KIC) for Microcrystalline Cellulose (MCC) using a developed tensile stress method and its application to double-layer tablets, The 5th World Congress on Particle Technology, Orlando, Session 38:b.
17. Jennings, R.J., 1988, A method for comparing beam-hardening filter materials for diagnostic radiology, Medical Physics, 15(4): 588-599.
18. Kak, A.C. 1979, Computerized tomography with X-ray, emission, and ultrasound sources, Proceedings of the IEEE, 67(9): 1245-1272.
19. Kak, A.C. and Slaney, M., 2001, Principles of Computerized Tomographic Imaging (SIAM, New York).
20. Karehill, P.G., Glazer, M. and Nystrom, C., 1990, Studies on direct compression of tablets. XXIII. The importance of surface roughness for the compactability of some directly compressible materials with different bonding and volume reduction properties, International Journal of Pharmaceutics, 64(1): 35-43.
21. Kendall, K. and Gregory, R.D., 1987, Fracture of radially edgecracked disks, Journal of Materials Science, 22(12): 4514-4517.
22. Mashadi, A.B. and Newton, J.M., 1987, The characterisation of the mechanical properties of microcrystalline cellulose: a fracture mechanics approach, Journal of Pharmacy and Pharmacology, 39: 961-965.
23. Mashadi, A.B. and Newton, J.M., 1988, Determination of the critical stress intensity factor (KIC) of compacted pharmaceutical powders by the double torsion method, Journal of Pharmacy and Pharmacology, 40: 597-600.
24. Melia, C., 1998, Magnetic resonance imaging of controlled release pharmaceutical dosage forms, Pharmaceutical Science & Technology Today, 1(1): 32-39.
25. Mohammed, H., Briscoe, B.J. and Pitt, K.G., 2005, The interrelationship between the compaction behaviour and the mechanical strength of pure pharmaceutical tablets, Chem Eng Sci, 60(14): 3941-3947.
26. Narayan, P. and Hancock, B.C., 2003, The relationship between the particle properties, mechanical behaviour, and surface roughness of some pharmaceutical excipient compacts, Materials Science and Engineering A, 355(1-2): 24-36.
27. Nebgen, G., Gross, D., Lehmann, V. and Muller, F., 1994, H-NMR microscopy of tablets, J Pharm Sci, 84(3): 283-291.
28. Nystrom, C., Alex, W. and Malmqvist, K., 1977, A new approach to tensile strength measurements of tablets, ActaPharm Suec, 14: 317-320.
29. Ozkan, N. and Briscoe, B.J., 1996, The surface topography of compacted agglomerates; a means to optimize compaction conditions, Powder Technol, 86(2): 201-207.
30. Podczeck, F., 1998, Particle-Particle Adhesion in Pharmaceutical Powder Handling (Imperial College Press, London).
31. Poon, C.Y. and Bhushan, B., 1995, Comparison of surface roughness measurements by stylus profiler, AFM and non-contact optical profiler, Wear, 190(1): 76-88.
32. Richardson, J., 2005, Pharmaceutical applications of magnetic resonance imaging (MRI), Advanced Drug Delivery Reviews, 57(8): 1191-1209.
33. Roberts, R.J. and Rowe, R.C., 1987, Brittle/ductile behaviour in pharmaceutical materials used in tabletting, International Journal of Pharmaceutics, 36(2-3): 205-209.
34. Roberts, R.J. and Rowe, R.C., 1989, Determination of the critical stress intensity factor (K) of microcrystalline cellulose using radially edge-cracked tablets, International Journal of Pharmaceutics, 52(3): 213-219.
35. Roberts, R.J., Rowe, R.C. and York, P., 1993, The measurement of the critical stress intensity factor (KIC) of pharmaceutical powders using three point single edge notched beam (SENB) testing, International Journal of Pharmaceutics, 91(2-3): 173-182.
36. Sasov, A., 2001, In High Resolution Microtomograph (Micro-CT), Proceedings of the 2nd World Congress on Industrial Process Tomography, Hannover, Germany, pp. 82-89.
37. Seitavuopio, P., Rantanen, J. and Yliruusi, J., 2003, Tablet surface characterisation by various imaging techniques, International Journal of Pharmaceutics, 254(2): 281-286.
38. Seitavuopio, P., Rantanen, J. and Yliruusi, J., 2005, Use of roughness maps in visualisation of surfaces, European Journal of Pharmaceutics and Biopharmaceutics, 59(2): 351-358.
39. Shangraw, R.F. and Demarest, D.A., 1993, A survey of current industrial practices in the formulation and manufacture of tablets and capsules, Pharmaceutical Technology, 17(1): 32.
40. Sinka, I.C., Burch, S.F., Tweed, J.H. and Cunningham, J.C., 2004, Measurement of density variations in tablets using X-ray computed tomography, International Journal of Pharmaceutics, 271(1-2): 215-224.
41. Stadler, A., Schima, W., Prager, G., Peter, H., Heinz, G., Saini, S., Eisenhuber, E. and Niederle, B., 2004, CT density measurements for characterization of adrenal tumors Ex Vivo: variability among three CT scanners, American Journal of Roentgenology, 182: 671-675.
42. Train, D., 1957, Transmission of forces through a powder made during the process of pelleting, Transactions of the Institution of Chemical Engineers, 35: 258-266.
43. Tritt-Goc, J., 2002, In situ, real time observation of the disintegration of paracetamol tablets in aqueous solution by magnetic resonance imaging, European Journal of Pharmaceutical Sciences, 15(4): 341-346.
44. Van de Casteele, E., 2004, In Model-based approach for Beam Hardening Correction and Resolution Measurements in Microtomogarphy, In PhD Thesis Universiteit Antwerpen, Antwerp.
45. Van de Casteele, E., Van Dyck, D., Sijbers, J. and Raman, E., 2002, An energy-based beam hardening model in tomography, Physics in Medicine and Biology, 47: 4181-4190.
46. Van de Casteele, E., Van Dyck, D., Sijbers, J. and Raman, E., 2004, Model-based correction method for beam hardening artefacts in X-ray microtomography, Journal of X-Ray Science and Technology, 12(1): 43-57.
47. Williams, J.G., 1984, Fracture Mechanics of Polymers (Ellis Horwood Ltd, Chichester).
48. York, P., Bassam, F., Rowe, R.C. and Roberts, R.J., 1990, Fracture mechanics of microcrystalline cellulose powders, International Journal of Pharmaceutics, 66(1-3): 143-148.
49. Young, S.W., Muller, H.H. and Marshall, W.H., 1983, Computed tomography: Beam hardening and environmental density artefact, Radiology, 148: 279-283.
50. Zatz, L.M. and Alvarez, R.E., 1977, An inaccuracy in computed tomography: The energy dependence of CT values, Radiology, 124: 91-97.