The novel histone deacetylase inhibitor thailandepsin A inhibits anaplastic thyroid cancer growth

Journal of Surgical Research

Volumn 190, Issue 1, 2014, Pages 191-197

  Weinlander, Eric ^a   Somnay, Yash ^a   Harrison, April D ^a   Wang, Cheng ^b   Cheng, Yi Qiang ^b,c   Jaskula Sztul, Renata ^a   Yu, Xiao Min ^a   Chen, Herbert ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^c UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

Anaplastic; Growth inhibition; HDAC inhibitor; TDP A; Thailandepsin A; Thyroid cancer

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CASPASE 3; CASPASE 9; HISTONE DEACETYLASE INHIBITOR; HISTONE H4; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROPIDIUM IODIDE; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; SURVIVIN; THAILANDEPSIN A INHIBITOR; UNCLASSIFIED DRUG;

ANAPLASTIC THYROID CANCER; APOPTOSIS; ARTICLE; CANCER CELL LINE; CANCER GROWTH; CANCER INHIBITION; CANCER STAGING; CELL CYCLE; CELL CYCLE ARREST; CELL DIVISION; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; COLORIMETRY; CONTROLLED STUDY; DRUG EFFECT; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IC 50; MTT ASSAY; PRIORITY JOURNAL; UPREGULATION; WESTERN BLOTTING;

ANAPLASTIC; GROWTH INHIBITION; HDAC INHIBITOR; TDP-A; THAILANDEPSIN A; THYROID CANCER;

APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; DEPSIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTONE DEACETYLASE INHIBITORS; HUMANS; THYROID NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84902287252     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2014.02.042     Document Type: Article

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