메뉴 건너뛰기




Volumn 4, Issue 5, 2008, Pages 935-947

Multi-targeted approach in the treatment of thyroid cancer

Author keywords

Epidermal growth factor receptor (EGFR); Glycogen synthase kinase 3 (GSK 3 ); RET tyrosine kinase (RTK); Thyroid carcinoma; Vascular endothelial growth factor receptor (VEGFR)

Indexed keywords

B RAF KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; IODINE 131; LEVOTHYROXINE; NOTCH1 RECEPTOR; PROTEIN P53; SUNITINIB; THYROTROPIN; TYROSINE KINASE RECEPTOR; VANDETANIB;

EID: 56749140670     PISSN: 11766336     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (20)

References (125)
  • 1
    • 33947593200 scopus 로고    scopus 로고
    • Accessed 8 January 2008. URL
    • American Cancer Society. 2007. Cancer Facts and Figures 2007. Accessed 8 January 2008. URL: http://www.cancer.org/downloads/STT/ CAFF2007PWSecured.pdf.
    • (2007) Cancer Facts and Figures 2007
  • 2
    • 56749115404 scopus 로고
    • Elective neck dissection in papillary carcinoma of the thyroid
    • Attie JN, Khafif RA, Steckler RM. 1971. Elective neck dissection in papillary carcinoma of the thyroid. Surgery, 111:604-9.
    • (1971) Surgery , vol.111 , pp. 604-609
    • Attie, J.N.1    Khafif, R.A.2    Steckler, R.M.3
  • 3
    • 0030986513 scopus 로고    scopus 로고
    • Low thyrotropin levels are not associated with bone loss in older women:A prospective study
    • Bauer D. 1997. Low thyrotropin levels are not associated with bone loss in older women:A prospective study. J Clin Endocrinol Metab, 82:2931-5.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2931-2935
    • Bauer, D.1
  • 4
    • 13144294026 scopus 로고    scopus 로고
    • Sporadic medullary microcarcinoma of the thyroid:a retrospective analysis of eighty cases
    • Beressi N, Campos JM, Beressi JP, et al. 1998. Sporadic medullary microcarcinoma of the thyroid:a retrospective analysis of eighty cases. Thyroid, 8:1039-44.
    • (1998) Thyroid , vol.8 , pp. 1039-1044
    • Beressi, N.1    Campos, J.M.2    Beressi, J.P.3
  • 5
    • 34548189836 scopus 로고    scopus 로고
    • Extent of surgery affects survival for papillary thyroid cancer
    • Bilimoria KY, Bentrem DJ, Ko CY, et al. 2007. Extent of surgery affects survival for papillary thyroid cancer. Ann Surg, 246:375-81.
    • (2007) Ann Surg , vol.246 , pp. 375-381
    • Bilimoria, K.Y.1    Bentrem, D.J.2    Ko, C.Y.3
  • 6
    • 0018931983 scopus 로고
    • Functional neck dissection: A description of operative technique
    • Bocca E, Pignataro O, Sasaki CT. 1980. Functional neck dissection: a description of operative technique. Arch Otolaryngol, 106:524-7.
    • (1980) Arch Otolaryngol , vol.106 , pp. 524-527
    • Bocca, E.1    Pignataro, O.2    Sasaki, C.T.3
  • 7
    • 0021258989 scopus 로고
    • Functional neck dissection: An evaluation and review of 843 cases
    • Bocca E, Pignataro O, Oldini C, et al. 1984. Functional neck dissection: an evaluation and review of 843 cases. Laryngoscope, 94:942-5.
    • (1984) Laryngoscope , vol.94 , pp. 942-945
    • Bocca, E.1    Pignataro, O.2    Oldini, C.3
  • 8
    • 0002802606 scopus 로고
    • Thyroid hormone in the treatment of thyroid cancer
    • Burmeister LA. 1994. Thyroid hormone in the treatment of thyroid cancer. Thyroid Today, 17:1-9.
    • (1994) Thyroid Today , vol.17 , pp. 1-9
    • Burmeister, L.A.1
  • 9
    • 0003594866 scopus 로고    scopus 로고
    • British Thyroid Association and Royal College of Physicians, 2nd ed, Accessed 9 January 2008. URL
    • British Thyroid Association and Royal College of Physicians. Guidelines for the management of thyroid cancer (2nd ed.). Accessed 9 January 2008. URL: http://www.british-thyroid-association.org/ Thyroid_cancer_guidelines_2007.pdf.
    • Guidelines for the management of thyroid cancer
  • 10
    • 0018648251 scopus 로고    scopus 로고
    • Byar DP, Green SB, Sor P, et al. 1979. A prognostic index for thyroid carcinoma: a study of the E.O.R.T.C. Thyroid Cancer Cooperative Group. Eur J Cancer, 15:1033-41.
    • Byar DP, Green SB, Sor P, et al. 1979. A prognostic index for thyroid carcinoma: a study of the E.O.R.T.C. Thyroid Cancer Cooperative Group. Eur J Cancer, 15:1033-41.
  • 11
    • 0018388868 scopus 로고
    • Risk factor analysis in differentiated thyroid cancer
    • Cady B, Sedhwick CE, Meissner WA, et al. 1979. Risk factor analysis in differentiated thyroid cancer. Cancer, 43:810-20.
    • (1979) Cancer , vol.43 , pp. 810-820
    • Cady, B.1    Sedhwick, C.E.2    Meissner, W.A.3
  • 12
    • 0037115405 scopus 로고    scopus 로고
    • ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases
    • Carlomagno F, Vitagliano D, Guida T, et al. 2002. ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases. Cancer Res, 62:7284-90.
    • (2002) Cancer Res , vol.62 , pp. 7284-7290
    • Carlomagno, F.1    Vitagliano, D.2    Guida, T.3
  • 13
    • 33751001783 scopus 로고    scopus 로고
    • Is tumor size the best predictor of outcome for papillary thyroid cancer?
    • Cheema Y, Repplinger D, Elson D, et al. 2006. Is tumor size the best predictor of outcome for papillary thyroid cancer? Ann Surg Oncol, 13:1524-8.
    • (2006) Ann Surg Oncol , vol.13 , pp. 1524-1528
    • Cheema, Y.1    Repplinger, D.2    Elson, D.3
  • 14
    • 22244454759 scopus 로고    scopus 로고
    • Medullary thyroid cancer:The functions of raf-1 and human achaete-scute homologue-1
    • Chen H, Kunnimalaiyaan M, Van Gompel JJ, et al. 2005. Medullary thyroid cancer:The functions of raf-1 and human achaete-scute homologue-1. Thyroid, 15:511-21.
    • (2005) Thyroid , vol.15 , pp. 511-521
    • Chen, H.1    Kunnimalaiyaan, M.2    Van Gompel, J.J.3
  • 15
    • 0032938454 scopus 로고    scopus 로고
    • Clinically significant, isolated metastatic disease to the thyroid gland
    • Chen H, Nicol TL, Udelsman R. 1999. Clinically significant, isolated metastatic disease to the thyroid gland. World J Surg, 23:177-80.
    • (1999) World J Surg , vol.23 , pp. 177-180
    • Chen, H.1    Nicol, T.L.2    Udelsman, R.3
  • 16
    • 0031596670 scopus 로고    scopus 로고
    • Hurthle cell neoplasms of the thyroid:Are there factors predictive of malignancy?
    • Chen H, Nicol TL, Zeiger MA, et al. 1998b. Hurthle cell neoplasms of the thyroid:Are there factors predictive of malignancy? Ann Surg, 227:542-6.
    • (1998) Ann Surg , vol.227 , pp. 542-546
    • Chen, H.1    Nicol, T.L.2    Zeiger, M.A.3
  • 17
    • 0032469373 scopus 로고    scopus 로고
    • Effective long-term palliation of symptomatic, incurable metastatic medullary thyroid cancer by operative resection
    • Chen H, Roberts JR, Ball DW, et al. 1998c. Effective long-term palliation of symptomatic, incurable metastatic medullary thyroid cancer by operative resection. Ann Surg, 227:887-95.
    • (1998) Ann Surg , vol.227 , pp. 887-895
    • Chen, H.1    Roberts, J.R.2    Ball, D.W.3
  • 18
    • 0031750936 scopus 로고    scopus 로고
    • Papillary thyroid carcinoma: Justification for total thyroidectomy and management of lymph node metastases
    • Chen H, Udelsman R. 1998. Papillary thyroid carcinoma: Justification for total thyroidectomy and management of lymph node metastases. Surg Oncol Clin N Am, 7:645-64.
    • (1998) Surg Oncol Clin N Am , vol.7 , pp. 645-664
    • Chen, H.1    Udelsman, R.2
  • 19
    • 0016785499 scopus 로고
    • Medullary carcinoma of the thyroid gland
    • Chong GC, Beahrs OH, Sizemore GW, et al. 1975. Medullary carcinoma of the thyroid gland. Cancer, 35:695-704.
    • (1975) Cancer , vol.35 , pp. 695-704
    • Chong, G.C.1    Beahrs, O.H.2    Sizemore, G.W.3
  • 20
    • 0019871023 scopus 로고
    • TSH suppression of thyroid nodules and thyroid cancer
    • Clark OH. 1981. TSH suppression of thyroid nodules and thyroid cancer. World J Surg, 5:39-46.
    • (1981) World J Surg , vol.5 , pp. 39-46
    • Clark, O.H.1
  • 21
    • 0019988248 scopus 로고
    • Total thyroidectomy:The treatment of choice for patients with differentiated thyroid cancer
    • Clark OH. 1982. Total thyroidectomy:The treatment of choice for patients with differentiated thyroid cancer. Ann Surg, 196:361-70.
    • (1982) Ann Surg , vol.196 , pp. 361-370
    • Clark, O.H.1
  • 23
    • 0022385405 scopus 로고
    • Thyrotropin receptor-adenylate cyclase system in Hurthle cell neoplasms
    • Clark OH, Gerend PL. 1985b. Thyrotropin receptor-adenylate cyclase system in Hurthle cell neoplasms. J Clin Endocrinol Metab, 61:773-8.
    • (1985) J Clin Endocrinol Metab , vol.61 , pp. 773-778
    • Clark, O.H.1    Gerend, P.L.2
  • 25
    • 33749149458 scopus 로고    scopus 로고
    • Variation in relative survival of thyroid cancers in Europe: Results from the analysis on 21 countries over the period 1983-1994 (EUROCARE-3 study)
    • Colonna M, Grande E, Jónasson JG, et al. 2006. Variation in relative survival of thyroid cancers in Europe: Results from the analysis on 21 countries over the period 1983-1994 (EUROCARE-3 study). Eur J Cancer, 42:2598-608.
    • (2006) Eur J Cancer , vol.42 , pp. 2598-2608
    • Colonna, M.1    Grande, E.2    Jónasson, J.G.3
  • 26
    • 33645465719 scopus 로고    scopus 로고
    • Management guidelines for patients with thyroid nodules and differentiated thyroid cancer
    • Cooper DS, Doherty GM, Haugen BR, et al. 2006. Management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid, 16:109-42.
    • (2006) Thyroid , vol.16 , pp. 109-142
    • Cooper, D.S.1    Doherty, G.M.2    Haugen, B.R.3
  • 27
    • 0034080079 scopus 로고    scopus 로고
    • Prognostic indicators in differentiated thyroid carcinoma
    • Dean DS, Hay ID. 2000. Prognostic indicators in differentiated thyroid carcinoma. Cancer Control, 7:229-39.
    • (2000) Cancer Control , vol.7 , pp. 229-239
    • Dean, D.S.1    Hay, I.D.2
  • 28
    • 0025063417 scopus 로고
    • Natural history, treatment, and course of papillary thyroid cancer
    • DeGroot LJ, Kaplan EL, McCortick M, et al. 1990. Natural history, treatment, and course of papillary thyroid cancer. J Clin Endocrinol Metab, 71:414-24.
    • (1990) J Clin Endocrinol Metab , vol.71 , pp. 414-424
    • DeGroot, L.J.1    Kaplan, E.L.2    McCortick, M.3
  • 29
    • 0032814519 scopus 로고    scopus 로고
    • Value of stimulated serum thyroglobulin levels for detecting persistent or recurrent differentiated thyroid cancer in high- and low-risk patients
    • Duren M, Siperstein AE, Shen W, et al. 1999. Value of stimulated serum thyroglobulin levels for detecting persistent or recurrent differentiated thyroid cancer in high- and low-risk patients. Surgery, 126:13-9.
    • (1999) Surgery , vol.126 , pp. 13-19
    • Duren, M.1    Siperstein, A.E.2    Shen, W.3
  • 30
    • 0027421148 scopus 로고
    • Diagnosis, treatment, and outcome of follicular thyroid carcinoma
    • Emerick GT, Duh QY, Siperstein AE, et al. 1993. Diagnosis, treatment, and outcome of follicular thyroid carcinoma. Cancer, 72:3287-95.
    • (1993) Cancer , vol.72 , pp. 3287-3295
    • Emerick, G.T.1    Duh, Q.Y.2    Siperstein, A.E.3
  • 31
    • 84924826425 scopus 로고
    • Papillary thyroid carcinoma:pathologica] findsings in cases with and without clinical evidence of cervical node involvement
    • Frazell EL, Foote FW. 1955. Papillary thyroid carcinoma:pathologica] findsings in cases with and without clinical evidence of cervical node involvement. Cancer, 8:1164-70.
    • (1955) Cancer , vol.8 , pp. 1164-1170
    • Frazell, E.L.1    Foote, F.W.2
  • 32
    • 0024595967 scopus 로고
    • Recurrence of thyroid nodules after removal in patients irradiated in childhood for benign conditions
    • Fogelfeld L, Wiviott MB, Shove-Freedman E, et al. 1989. Recurrence of thyroid nodules after removal in patients irradiated in childhood for benign conditions. N Engl J Med, 320:835-40.
    • (1989) N Engl J Med , vol.320 , pp. 835-840
    • Fogelfeld, L.1    Wiviott, M.B.2    Shove-Freedman, E.3
  • 33
    • 0031926082 scopus 로고    scopus 로고
    • Determinative factors of biochemical cure after primary and reoperative surgery for sporadic medullary thyroid carcinoma
    • Gimm, O, Ukkat J, Dralle H. 1999. Determinative factors of biochemical cure after primary and reoperative surgery for sporadic medullary thyroid carcinoma. World J Surg, 22:562-7.
    • (1999) World J Surg , vol.22 , pp. 562-567
    • Gimm, O.1    Ukkat, J.2    Dralle, H.3
  • 34
    • 0030028104 scopus 로고    scopus 로고
    • Thyroid cancer nodal metastases:biologic significance and therapeutic considerations
    • Grebe SK, Hay ID. 1996. Thyroid cancer nodal metastases:biologic significance and therapeutic considerations. Surg Oncol Clin N Am, 5:43-63.
    • (1996) Surg Oncol Clin N Am , vol.5 , pp. 43-63
    • Grebe, S.K.1    Hay, I.D.2
  • 35
    • 34249672300 scopus 로고    scopus 로고
    • Initial lymph node dissection increases cure rates in patients with medullary thyroid cancer
    • Greenblatt DY, Elson D, Mack E, et al. 2007. Initial lymph node dissection increases cure rates in patients with medullary thyroid cancer. Asian J Surg, 30:108-12.
    • (2007) Asian J Surg , vol.30 , pp. 108-112
    • Greenblatt, D.Y.1    Elson, D.2    Mack, E.3
  • 36
    • 56749109161 scopus 로고    scopus 로고
    • Thyroid Malignancies
    • Townsend CM, Beauchamp RD, Evers BM, et al, eds, 17th ed. Philadelphia: Saunders. p
    • Hanks JB. 2004. Thyroid Malignancies. In Townsend CM, Beauchamp RD, Evers BM, et al. (eds). Sabiston Textbook of Surgery. 17th ed. Philadelphia: Saunders. p. 965-73.
    • (2004) Sabiston Textbook of Surgery , pp. 965-973
    • Hanks, J.B.1
  • 37
    • 0037205315 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β:a novel regulator of cardiac hypertrophy and development
    • Hardt SE, Sadoshima J. 2002. Glycogen synthase kinase-3β:a novel regulator of cardiac hypertrophy and development. Circ Res, 90:1055-63.
    • (2002) Circ Res , vol.90 , pp. 1055-1063
    • Hardt, S.E.1    Sadoshima, J.2
  • 38
    • 0028870305 scopus 로고
    • Glycogen synthase kinase 3 regulates cell fate in Dictyostelium
    • Harwood AJ, Plyte SE, Woodgett J, et al. 1995. Glycogen synthase kinase 3 regulates cell fate in Dictyostelium Cell, 80:139-48.
    • (1995) Cell , vol.80 , pp. 139-148
    • Harwood, A.J.1    Plyte, S.E.2    Woodgett, J.3
  • 39
    • 0031723678 scopus 로고    scopus 로고
    • Management of the patient with progressive radio-iodine non-responsive disease
    • Haugen BR. 1999. Management of the patient with progressive radio-iodine non-responsive disease. Semin Surg Oncol, 16:34-41.
    • (1999) Semin Surg Oncol , vol.16 , pp. 34-41
    • Haugen, B.R.1
  • 40
    • 0027135424 scopus 로고
    • Predicting outcome in papillary thyroid cancer: Development of a reliable prognostic scoring system in a cohort of 1779 patients surgically treated at one institution during 1940 through 1989
    • Hay ID, Bergstralh EJ, Goellner JR, et al. 1993. Predicting outcome in papillary thyroid cancer: development of a reliable prognostic scoring system in a cohort of 1779 patients surgically treated at one institution during 1940 through 1989. Surgery, 114:1050-8.
    • (1993) Surgery , vol.114 , pp. 1050-1058
    • Hay, I.D.1    Bergstralh, E.J.2    Goellner, J.R.3
  • 41
    • 0031762998 scopus 로고    scopus 로고
    • Unilateral total lobectomy: Is it sufficient surgical treatment for patients with AMES low-risk papillary thyroid carcinoma?
    • Hay ID, Grant CS, Bergstralh EJ, et al. 1998. Unilateral total lobectomy: Is it sufficient surgical treatment for patients with AMES low-risk papillary thyroid carcinoma? Surgery, 124:958-66.
    • (1998) Surgery , vol.124 , pp. 958-966
    • Hay, I.D.1    Grant, C.S.2    Bergstralh, E.J.3
  • 42
    • 0002049474 scopus 로고
    • Histologic typing of thyroid tumors
    • Hedinger C, Williams ED, Sobin LH, eds, Geneva: World Health Organization;
    • Hedinger C, Williams ED, Sobin LH, eds. 1988. Histologic typing of thyroid tumors. In: International Histological Classification of Tumors, No.11. Geneva: World Health Organization; 1-18.
    • (1988) International Histological Classification of Tumors , Issue.11 , pp. 1-18
  • 43
    • 22844439856 scopus 로고    scopus 로고
    • Hip bone mineral density, bone turnover and risk of fracture in patients on long-term suppressive L-thyroxine therapy for differentiated thyroid carcinoma
    • Heijckmann AC, Huijberts MS, Guesens P, et al. 2005. Hip bone mineral density, bone turnover and risk of fracture in patients on long-term suppressive L-thyroxine therapy for differentiated thyroid carcinoma. Fur J Endocrinol, 153:23-9.
    • (2005) Fur J Endocrinol , vol.153 , pp. 23-29
    • Heijckmann, A.C.1    Huijberts, M.S.2    Guesens, P.3
  • 44
    • 0027965686 scopus 로고
    • Epidermal growth factor enhances proliferation, migration, and invasion of follicular and papillary thyroid cancer in vitro and in vivo
    • Hoelting T, Siperstein AE, Clark OH, et al. 1994. Epidermal growth factor enhances proliferation, migration, and invasion of follicular and papillary thyroid cancer in vitro and in vivo. J Clin Endocrinol Metab, 79:401-8.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 401-408
    • Hoelting, T.1    Siperstein, A.E.2    Clark, O.H.3
  • 45
    • 23844544081 scopus 로고    scopus 로고
    • Clinical evaluation of ZD6474, an orally active inhibitor of VEGF and EGF receptor signaling, in patients with solid, malignant tumors
    • Holden SN, Eckhardt SG, Basser R, et al. 2005. Clinical evaluation of ZD6474, an orally active inhibitor of VEGF and EGF receptor signaling, in patients with solid, malignant tumors. Ann Oncol, 16:1391-7.
    • (2005) Ann Oncol , vol.16 , pp. 1391-1397
    • Holden, S.N.1    Eckhardt, S.G.2    Basser, R.3
  • 46
    • 0032535770 scopus 로고    scopus 로고
    • A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the US, 1985-1995
    • Hundahl SA, Fleming ID, Fremgen AM, et al. 1998. A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the US, 1985-1995. Cancer, 83:2638-48.
    • (1998) Cancer , vol.83 , pp. 2638-2648
    • Hundahl, S.A.1    Fleming, I.D.2    Fremgen, A.M.3
  • 47
    • 40949115590 scopus 로고    scopus 로고
    • Appropriate treatment for asymptomatic papillary microcarcinoma of the thyroid
    • Ito Y, Miyauchi A. 2007. Appropriate treatment for asymptomatic papillary microcarcinoma of the thyroid. Expert Opin Pharmacother, 8:3205-15.
    • (2007) Expert Opin Pharmacother , vol.8 , pp. 3205-3215
    • Ito, Y.1    Miyauchi, A.2
  • 48
    • 0038702077 scopus 로고    scopus 로고
    • An observation trial without surgical treatment in patients with papillary microcarcinoma of the thyroid
    • Ito Y, Uruno T, Nakanao K, et al. 2003. An observation trial without surgical treatment in patients with papillary microcarcinoma of the thyroid. Thyroid, 13(4):381-7.
    • (2003) Thyroid , vol.13 , Issue.4 , pp. 381-387
    • Ito, Y.1    Uruno, T.2    Nakanao, K.3
  • 49
    • 5444247778 scopus 로고    scopus 로고
    • Notch signaling: The demise of elegant simplicity
    • Kadesch T. 2004. Notch signaling: The demise of elegant simplicity. Curr Opin Genet Dev, 14:506-12.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 506-512
    • Kadesch, T.1
  • 50
    • 0026756086 scopus 로고
    • Multiple thyroid involvement (intraglandular metastases) in papillary thyroid carcinoma. A clinicopathologic study of 105 consecutive patients
    • Katoh R, Sasaki J, Kurihara H, et al. 1992. Multiple thyroid involvement (intraglandular metastases) in papillary thyroid carcinoma. A clinicopathologic study of 105 consecutive patients. Cancer, 70:1585-90.
    • (1992) Cancer , vol.70 , pp. 1585-1590
    • Katoh, R.1    Sasaki, J.2    Kurihara, H.3
  • 52
    • 34548192281 scopus 로고    scopus 로고
    • The prevalence and prognostic value of BRAF mutation in thyroid cancer
    • Kebebew E, Weng J, Bauer J, et al. 2007. The prevalence and prognostic value of BRAF mutation in thyroid cancer. Ann Surg, 246:466-71.
    • (2007) Ann Surg , vol.246 , pp. 466-471
    • Kebebew, E.1    Weng, J.2    Bauer, J.3
  • 53
    • 0037382237 scopus 로고    scopus 로고
    • Guidelines for the management of thyroid cancer
    • Guidelines Working Group
    • Kendall-Taylor P, Guidelines Working Group. 2003. Guidelines for the management of thyroid cancer. Clin Endocrinol (Oxf), 58:400-2.
    • (2003) Clin Endocrinol (Oxf) , vol.58 , pp. 400-402
    • Kendall-Taylor, P.1
  • 54
    • 33749544080 scopus 로고    scopus 로고
    • An orally administered multitarget tyrosine kinase inhibitor, SU11248, is a novel potent inhibitor of thyroid oncogenic RET/papillary thyroid cancer kinases
    • Kim DW, Jo YS, Jung HS, et al. 2006. An orally administered multitarget tyrosine kinase inhibitor, SU11248, is a novel potent inhibitor of thyroid oncogenic RET/papillary thyroid cancer kinases. J Clin Endocrinol Metab, 91:4070-6.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 4070-4076
    • Kim, D.W.1    Jo, Y.S.2    Jung, H.S.3
  • 55
    • 34250704834 scopus 로고    scopus 로고
    • Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice
    • Kim S, Yazici TD, Calzada G, et al. 2007. Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice. Mol Cancer Ther, 6:1785-92.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1785-1792
    • Kim, S.1    Yazici, T.D.2    Calzada, G.3
  • 56
    • 0037379904 scopus 로고    scopus 로고
    • High prevalence of BRAF mutations in thyroid cancer:genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma
    • Kimura ET, Nikiforova MN, Zhu Z, et al. 2003. High prevalence of BRAF mutations in thyroid cancer:genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma. Cancer Res, 63:1454-7.
    • (2003) Cancer Res , vol.63 , pp. 1454-1457
    • Kimura, E.T.1    Nikiforova, M.N.2    Zhu, Z.3
  • 57
    • 0017626123 scopus 로고
    • 131 therapy in the management of thyroid cancer. A prospective study
    • 131 therapy in the management of thyroid cancer. A prospective study. Cancer, 40:195-202.
    • (1977) Cancer , vol.40 , pp. 195-202
    • Krishnamurthy, G.T.1    Blahd, W.H.2
  • 58
    • 34147103403 scopus 로고    scopus 로고
    • Treatment for microcarcinoma of the thyroid - clinical experience
    • Küçük NO, Tari P, Tokmak E, et al. 2007. Treatment for microcarcinoma of the thyroid - clinical experience. Clin Nucl Med, 32:279-81.
    • (2007) Clin Nucl Med , vol.32 , pp. 279-281
    • Küçük, N.O.1    Tari, P.2    Tokmak, E.3
  • 59
    • 33646248388 scopus 로고    scopus 로고
    • The Raf-1 pathway:a molecular target for treatment of select neuroendocrine tumors?
    • Kunnimalaiyaan M, Chen H. 2006. The Raf-1 pathway:a molecular target for treatment of select neuroendocrine tumors? Anticancer Drugs, 17:139-42.
    • (2006) Anticancer Drugs , vol.17 , pp. 139-142
    • Kunnimalaiyaan, M.1    Chen, H.2
  • 60
    • 34548452775 scopus 로고    scopus 로고
    • Tumor suppressor role of Notch-1 signaling in neuroendocrine tumors
    • Kunnimalaiyaan M, Chen H. 2007. Tumor suppressor role of Notch-1 signaling in neuroendocrine tumors. Oncologist, 12:535-42.
    • (2007) Oncologist , vol.12 , pp. 535-542
    • Kunnimalaiyaan, M.1    Chen, H.2
  • 61
    • 56749145596 scopus 로고    scopus 로고
    • Tumor suppressor role of Notch1 and Raf-1 signaling in medullary thyroid cancer cells
    • Kunnimalaiyaan M, Haymart M, Chen H. 2007a. Tumor suppressor role of Notch1 and Raf-1 signaling in medullary thyroid cancer cells. Translational Oncogenomics, 2:43-7.
    • (2007) Translational Oncogenomics , vol.2 , pp. 43-47
    • Kunnimalaiyaan, M.1    Haymart, M.2    Chen, H.3
  • 62
    • 33845987566 scopus 로고    scopus 로고
    • Overexpression of the NOTCH1 intracellular domain inhibits cell proliferation and alters the neuroendocrine phenotype of medullary thyroid cancer cells
    • Kunnimalaiyaan M, Vaccaro AM, Ndiaye M, et al. 2006. Overexpression of the NOTCH1 intracellular domain inhibits cell proliferation and alters the neuroendocrine phenotype of medullary thyroid cancer cells. J Biol Chem, 281:39819-30.
    • (2006) J Biol Chem , vol.281 , pp. 39819-39830
    • Kunnimalaiyaan, M.1    Vaccaro, A.M.2    Ndiaye, M.3
  • 63
    • 34147168760 scopus 로고    scopus 로고
    • Inactivation of glycogen synthase kinase-3β, a downstream target of the raf-1 pathway, is associated with growth suppression in medullary thyroid cancer cells
    • Kunnimalaiyaan M, Vaccaro AM, Ndiaye MA, et al. 2007b. Inactivation of glycogen synthase kinase-3β, a downstream target of the raf-1 pathway, is associated with growth suppression in medullary thyroid cancer cells. Mol Cancer Ther, 6:1151-8.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1151-1158
    • Kunnimalaiyaan, M.1    Vaccaro, A.M.2    Ndiaye, M.A.3
  • 64
    • 0034011887 scopus 로고    scopus 로고
    • Insular and anaplastic carcinoma of the thyroid:A 45-year comparative study at a single institution and a review of the significance of p53 and p21
    • Lam KY, Lo CY, Chan KW, et al. 2000. Insular and anaplastic carcinoma of the thyroid:A 45-year comparative study at a single institution and a review of the significance of p53 and p21. Ann Surg, 231:329-38.
    • (2000) Ann Surg , vol.231 , pp. 329-338
    • Lam, K.Y.1    Lo, C.Y.2    Chan, K.W.3
  • 65
    • 34248203755 scopus 로고    scopus 로고
    • Surgical options in undifferentiated thyroid carcinoma
    • Lang BH, Lo CY. 2007. Surgical options in undifferentiated thyroid carcinoma. World J Surg, 31:969-77.
    • (2007) World J Surg , vol.31 , pp. 969-977
    • Lang, B.H.1    Lo, C.Y.2
  • 66
    • 31544480126 scopus 로고    scopus 로고
    • Clincally significant prognostic factors for differentiated thyroid carcinoma:a population-based, nested case-control study
    • Lundgren CI, Hall P, Dickman PW, et al. 2006. Clincally significant prognostic factors for differentiated thyroid carcinoma:a population-based, nested case-control study. Cancer, 106:524-31.
    • (2006) Cancer , vol.106 , pp. 524-531
    • Lundgren, C.I.1    Hall, P.2    Dickman, P.W.3
  • 67
    • 0346368237 scopus 로고    scopus 로고
    • Skip metastases in thyroid cancer leaping the central lymph node compartment
    • Machens A, Holzhausen HJ, Dralle H. 2004. Skip metastases in thyroid cancer leaping the central lymph node compartment. Arch Surg, 139:43-5.
    • (2004) Arch Surg , vol.139 , pp. 43-45
    • Machens, A.1    Holzhausen, H.J.2    Dralle, H.3
  • 68
    • 34548688232 scopus 로고    scopus 로고
    • Increased risk of lymph node metastasis in multifocal hereditary and sporadic medullary thyroid cancer
    • Machens A, Hauptmann S, Dralle H. 2007. Increased risk of lymph node metastasis in multifocal hereditary and sporadic medullary thyroid cancer. World J Surg, 31:1960-5.
    • (2007) World J Surg , vol.31 , pp. 1960-1965
    • Machens, A.1    Hauptmann, S.2    Dralle, H.3
  • 69
    • 0042286558 scopus 로고    scopus 로고
    • Notch and cancer:Best to avoid the ups and downs
    • Maillard I, Pear WS. 2003. Notch and cancer:Best to avoid the ups and downs. Cancer Cell, 3:203-5.
    • (2003) Cancer Cell , vol.3 , pp. 203-205
    • Maillard, I.1    Pear, W.S.2
  • 71
    • 0035479144 scopus 로고    scopus 로고
    • The RET receptor:function in development and dysfunction in congenital malformation
    • Manie S, Santoro M, Fusco A, et al. 2001. The RET receptor:function in development and dysfunction in congenital malformation. Trends Genet, 17:580-9.
    • (2001) Trends Genet , vol.17 , pp. 580-589
    • Manie, S.1    Santoro, M.2    Fusco, A.3
  • 72
    • 0023408270 scopus 로고
    • Papillary thyroid carcinoma:factors influencing prognosis and current therapy
    • Mazzaferri E. 1988. Papillary thyroid carcinoma:factors influencing prognosis and current therapy. Semin Oncol, 14:315-32.
    • (1988) Semin Oncol , vol.14 , pp. 315-332
    • Mazzaferri, E.1
  • 73
    • 0000698642 scopus 로고    scopus 로고
    • NCCN thyroid carcinoma practice guidelines
    • Mazzaferri EL. 1999. NCCN thyroid carcinoma practice guidelines. Oncology, 13:391-42.
    • (1999) Oncology , vol.13 , pp. 391-442
    • Mazzaferri, E.L.1
  • 74
    • 35148819235 scopus 로고    scopus 로고
    • Management of low-risk differentiated thyroid cancer
    • Mazzaferri EL. 2007. Management of low-risk differentiated thyroid cancer. Endocr Pr, 13:498-512.
    • (2007) Endocr Pr , vol.13 , pp. 498-512
    • Mazzaferri, E.L.1
  • 75
    • 0027943619 scopus 로고
    • Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer
    • Mazzaferri EL, Jhiang SM. 1994. Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer. Am J Med, 97:418-28.
    • (1994) Am J Med , vol.97 , pp. 418-428
    • Mazzaferri, E.L.1    Jhiang, S.M.2
  • 76
    • 0017693511 scopus 로고
    • Papillary thyroid carcinoma: The impact of therapy in 576 patients
    • Mazzaferri E, Young RL, Oertel JE, et al. 1977. Papillary thyroid carcinoma: The impact of therapy in 576 patients. Medicine, 56:171-96.
    • (1977) Medicine , vol.56 , pp. 171-196
    • Mazzaferri, E.1    Young, R.L.2    Oertel, J.E.3
  • 77
    • 56749113901 scopus 로고
    • Papillary thyroid carcinoma:A 10 year follow-up report of the impact of therapy in 576 patients
    • Mazzaferri E, Young RL. 1981. Papillary thyroid carcinoma:A 10 year follow-up report of the impact of therapy in 576 patients. Am J Med, 70:551-558.
    • (1981) Am J Med , vol.70 , pp. 551-558
    • Mazzaferri, E.1    Young, R.L.2
  • 78
    • 33748741639 scopus 로고    scopus 로고
    • Epidermal growth factor receptor as a therapeutic target in human thyroid carcinoma:mutational and functional analysis
    • Mitsiades CS, Kotoula V, Poulaki V, et al. 2006. Epidermal growth factor receptor as a therapeutic target in human thyroid carcinoma:mutational and functional analysis. J Clin Endocrinol Metab, 91:3662-6.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 3662-3666
    • Mitsiades, C.S.1    Kotoula, V.2    Poulaki, V.3
  • 79
    • 0031050368 scopus 로고    scopus 로고
    • p53 re-expression inhibits proliferation and restores differentiation of human thyroid anaplastic carcinoma cells
    • Moretti F, Farsetti A, Soddu S, et al. 1997. p53 re-expression inhibits proliferation and restores differentiation of human thyroid anaplastic carcinoma cells. Oncogene, 14:729-40.
    • (1997) Oncogene , vol.14 , pp. 729-740
    • Moretti, F.1    Farsetti, A.2    Soddu, S.3
  • 80
    • 84871399634 scopus 로고    scopus 로고
    • National Cancer Institute Surveillance Epidemiology and End Results Database, URL:, accessed March 28, 2008
    • [NCI] National Cancer Institute Surveillance Epidemiology and End Results Database, US National Institutes of Health. URL: http://seer.cancer.gov/statfacts/html/thyro.html; accessed March 28, 2008.
    • US National Institutes of Health
  • 81
    • 0036258111 scopus 로고    scopus 로고
    • The IARC TP53 database: New online mutation analysis and recommendations to users
    • Olivier M, Eeles R, Hollstein M, et al. 2002. The IARC TP53 database: new online mutation analysis and recommendations to users. Hum Mutat, 19:607-14.
    • (2002) Hum Mutat , vol.19 , pp. 607-614
    • Olivier, M.1    Eeles, R.2    Hollstein, M.3
  • 82
    • 0028333953 scopus 로고
    • Serum thyroglobulin in the follow-up of patients with treated differentiated thyroid cancer
    • Ozata M, Suzuki S, Miyamoto T, et al. 1994. Serum thyroglobulin in the follow-up of patients with treated differentiated thyroid cancer. J Clin Endocrinol Metab, 79:98-105.
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 98-105
    • Ozata, M.1    Suzuki, S.2    Miyamoto, T.3
  • 83
    • 0031721605 scopus 로고    scopus 로고
    • Guidelines for the use of radioiodine, thyroid hormone, and treatment of metastatic disease in patients with differentiated thyroid cancer
    • Paloyan E, Walker RP, Lawrence AM. 1998. Guidelines for the use of radioiodine, thyroid hormone, and treatment of metastatic disease in patients with differentiated thyroid cancer. Surg Oncol Clin N Am, 7:665-80.
    • (1998) Surg Oncol Clin N Am , vol.7 , pp. 665-680
    • Paloyan, E.1    Walker, R.P.2    Lawrence, A.M.3
  • 84
    • 0037221065 scopus 로고    scopus 로고
    • The ras/raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway
    • Park JI, Strock CJ, Ball DW, et al. 2003. The ras/raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway. Mol Cell Biol, 23:543-54.
    • (2003) Mol Cell Biol , vol.23 , pp. 543-554
    • Park, J.I.1    Strock, C.J.2    Ball, D.W.3
  • 85
    • 34548176606 scopus 로고    scopus 로고
    • Introduction to the updated guidelines on the management of thyroid cancer
    • Thyroid Cancer Guidelines Update Group
    • Perros P, Thyroid Cancer Guidelines Update Group. 2007. Introduction to the updated guidelines on the management of thyroid cancer. Clin Med, 7:321-2.
    • (2007) Clin Med , vol.7 , pp. 321-322
    • Perros, P.1
  • 86
    • 0029827464 scopus 로고    scopus 로고
    • Degree of thyrotropin suppression as a prognostic determinant in differentiated thyroid cancer
    • Pujol P, Daures JP, Nsakala N, et al. Degree of thyrotropin suppression as a prognostic determinant in differentiated thyroid cancer. J Clin Endocrinol Metab, 81:4318-23.
    • J Clin Endocrinol Metab , vol.81 , pp. 4318-4323
    • Pujol, P.1    Daures, J.P.2    Nsakala, N.3
  • 87
    • 0036119585 scopus 로고    scopus 로고
    • Distribution of lymph node micrometastases in pN0 well-differentiated thyroid carcinoma
    • Qubain SW, Nakano S, Baba M, et al. 2002. Distribution of lymph node micrometastases in pN0 well-differentiated thyroid carcinoma. Surgery, 131:249-56.
    • (2002) Surgery , vol.131 , pp. 249-256
    • Qubain, S.W.1    Nakano, S.2    Baba, M.3
  • 88
    • 0033113378 scopus 로고    scopus 로고
    • Raf-1 causes growth suppression and alteration of neuroendocrine markers in DMS53 human small cell lung cancer cells
    • Ravi RK, Thiagalingam A, Weber E, et al. 1999. Raf-1 causes growth suppression and alteration of neuroendocrine markers in DMS53 human small cell lung cancer cells. Am J Respir Cell Mol Biol, 20:543-9.
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 543-549
    • Ravi, R.K.1    Thiagalingam, A.2    Weber, E.3
  • 89
    • 0031985094 scopus 로고    scopus 로고
    • Activated raf-1 causes growth arrest in human small cell lung cancers
    • Ravi RK, Weber E, McMahon, et al. 1998. Activated raf-1 causes growth arrest in human small cell lung cancers. J Clin Invest, 101:153-9.
    • (1998) J Clin Invest , vol.101 , pp. 153-159
    • Ravi, R.K.1    Weber, E.2    McMahon3
  • 91
    • 0021746211 scopus 로고
    • Medullary carcinoma of the thyroid:a study of the clinical features and prognostic factors in 161 patients
    • Saad MF, Ordonez NG, Rashid RK, et al. 1984. Medullary carcinoma of the thyroid:a study of the clinical features and prognostic factors in 161 patients. Medicine (Baltimore), 63:319-342.
    • (1984) Medicine (Baltimore) , vol.63 , pp. 319-342
    • Saad, M.F.1    Ordonez, N.G.2    Rashid, R.K.3
  • 92
    • 33845565405 scopus 로고    scopus 로고
    • Patterns of expression of cell cycle/apoptosis genes along the spectmm of thyroid carcinoma progression
    • Saltman B, Singh B, Hedvat CV, et al. 2006. Patterns of expression of cell cycle/apoptosis genes along the spectmm of thyroid carcinoma progression. Surgery, 140:899-906.
    • (2006) Surgery , vol.140 , pp. 899-906
    • Saltman, B.1    Singh, B.2    Hedvat, C.V.3
  • 93
    • 33645069923 scopus 로고    scopus 로고
    • BRAF is a therapeutic target in aggressive thyroid carcinoma
    • Salvatore G, De Falco V, Salerno P, et al. 2006. BRAF is a therapeutic target in aggressive thyroid carcinoma. Clin Cancer Res, 12:1623-9.
    • (2006) Clin Cancer Res , vol.12 , pp. 1623-1629
    • Salvatore, G.1    De Falco, V.2    Salerno, P.3
  • 94
    • 0031943356 scopus 로고    scopus 로고
    • Differentiated thyroid cancer:Reexamination of risk groups and outcome of treatment
    • Sanders LE, Cady B. 1998. Differentiated thyroid cancer:Reexamination of risk groups and outcome of treatment. Arch Surg, 133:419-25.
    • (1998) Arch Surg , vol.133 , pp. 419-425
    • Sanders, L.E.1    Cady, B.2
  • 95
    • 40749087651 scopus 로고    scopus 로고
    • A systematic review of the gonadal effects of therapeutic radioactive iodine in male thyroid cancer survivors
    • Sawka AM, Lakra DC, Lea J, et al. 2008a. A systematic review of the gonadal effects of therapeutic radioactive iodine in male thyroid cancer survivors. Clin Endocrinol, 68:610-7.
    • (2008) Clin Endocrinol , vol.68 , pp. 610-617
    • Sawka, A.M.1    Lakra, D.C.2    Lea, J.3
  • 96
    • 49649125886 scopus 로고    scopus 로고
    • A systematic review examining the effects of therapeutic radioactive iodine on ovarian function and future pregnancy in female thyroid cancer survivors
    • Feb 13
    • Sawka AM, Lakra DC, Lea J, et al. 2008b. A systematic review examining the effects of therapeutic radioactive iodine on ovarian function and future pregnancy in female thyroid cancer survivors. Clin Endocrinol, Feb 13.
    • (2008) Clin Endocrinol
    • Sawka, A.M.1    Lakra, D.C.2    Lea, J.3
  • 97
    • 0018090493 scopus 로고
    • Incidence, prevalence, and characteristics of radiation-induced thyroid tumors
    • Schneider AB, Favus MJ, Stachoura ME, et al. 1978. Incidence, prevalence, and characteristics of radiation-induced thyroid tumors. Am J Med, 64:243-52.
    • (1978) Am J Med , vol.64 , pp. 243-252
    • Schneider, A.B.1    Favus, M.J.2    Stachoura, M.E.3
  • 98
    • 0038369070 scopus 로고    scopus 로고
    • Rationale for central and bilateral lymph node dissection in sporadic and hereditary medullary thyroid cancer
    • Scollo C, Baudin E, Travalgi JP, et al. 2003. Rationale for central and bilateral lymph node dissection in sporadic and hereditary medullary thyroid cancer. J Clin Endocrinol Metab, 88:2070-5.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2070-2075
    • Scollo, C.1    Baudin, E.2    Travalgi, J.P.3
  • 99
    • 0031738882 scopus 로고    scopus 로고
    • Management of the neck in thyroid cancer
    • Shaha AR. 1998. Management of the neck in thyroid cancer. Otolaryngol Clin North Am, 31:823-31.
    • (1998) Otolaryngol Clin North Am , vol.31 , pp. 823-831
    • Shaha, A.R.1
  • 100
    • 0037425748 scopus 로고    scopus 로고
    • Thyroid carcinoma
    • Sherman SI. 2003. Thyroid carcinoma. Lancet, 361:501-11.
    • (2003) Lancet , vol.361 , pp. 501-511
    • Sherman, S.I.1
  • 101
    • 0024845652 scopus 로고
    • The effect of thyroid hormone on the growth of thyroid cancer [Japanese]
    • Shiba E, Miyauchi K, Kobayashi T, et al. 1989. The effect of thyroid hormone on the growth of thyroid cancer [Japanese]. Gan To Kagaku Ryoho, 16:3678-84.
    • (1989) Gan To Kagaku Ryoho , vol.16 , pp. 3678-3684
    • Shiba, E.1    Miyauchi, K.2    Kobayashi, T.3
  • 102
    • 0014774333 scopus 로고
    • Fatal carcinoma of the thyroid: Histology, metastases, and causes of death
    • Silverberg SG, Hutter RVP, Foote FW Jr. 1970. Fatal carcinoma of the thyroid: histology, metastases, and causes of death. Cancer, 25:792-802.
    • (1970) Cancer , vol.25 , pp. 792-802
    • Silverberg, S.G.1    Hutter, R.V.P.2    Foote Jr., F.W.3
  • 103
    • 0029808326 scopus 로고    scopus 로고
    • Incidence of regional recurrence guiding radicality in differentiated thyroid carcinoma
    • Simon D, Goretzki PE, Witte J, et al. 1996. Incidence of regional recurrence guiding radicality in differentiated thyroid carcinoma. World J Surg, 20:860-6.
    • (1996) World J Surg , vol.20 , pp. 860-866
    • Simon, D.1    Goretzki, P.E.2    Witte, J.3
  • 104
    • 0346887056 scopus 로고    scopus 로고
    • The role of human achaete-scute homolog-1 in medullary thyroid cancer cells
    • Sippel RS, Carpenter JE, Kunnimalaiyaan M, et al. 2003. The role of human achaete-scute homolog-1 in medullary thyroid cancer cells. Surgery, 134:866-71.
    • (2003) Surgery , vol.134 , pp. 866-871
    • Sippel, R.S.1    Carpenter, J.E.2    Kunnimalaiyaan, M.3
  • 105
    • 0034999034 scopus 로고    scopus 로고
    • Salivary and lacrimal gland dysfunction (sicca syndrome) after radioiodine therapy
    • Solans R, Bosch JA, Galofré P, et al. 2001. Salivary and lacrimal gland dysfunction (sicca syndrome) after radioiodine therapy. J Nucl Med, 42:738-43.
    • (2001) J Nucl Med , vol.42 , pp. 738-743
    • Solans, R.1    Bosch, J.A.2    Galofré, P.3
  • 106
    • 0036121511 scopus 로고    scopus 로고
    • The important role of operations in the management of anaplastic carcinoma
    • Sugino K, Ito K, Mimura T, et al. 2002. The important role of operations in the management of anaplastic carcinoma. Surgery, 131:245-8.
    • (2002) Surgery , vol.131 , pp. 245-248
    • Sugino, K.1    Ito, K.2    Mimura, T.3
  • 107
    • 33845591066 scopus 로고    scopus 로고
    • Routine ipsilateral level VI lymphadenopathy reduces postoperative thyroglobulin levels in papillary thyroid cancer
    • Sywak M, Cornford L, Roach P, et al. 2006. Routine ipsilateral level VI lymphadenopathy reduces postoperative thyroglobulin levels in papillary thyroid cancer. Surgery, 140:1000-7.
    • (2006) Surgery , vol.140 , pp. 1000-1007
    • Sywak, M.1    Cornford, L.2    Roach, P.3
  • 108
    • 33846844387 scopus 로고    scopus 로고
    • A Phase I dose-escalation study of ZD6474 in Japanese patients with solid, malignant tumors
    • Tamura T, Minami H, Yamada Y, et al. 2006. A Phase I dose-escalation study of ZD6474 in Japanese patients with solid, malignant tumors. J Thorac Oncol, 1:1002-9.
    • (2006) J Thorac Oncol , vol.1 , pp. 1002-1009
    • Tamura, T.1    Minami, H.2    Yamada, Y.3
  • 109
    • 0034986658 scopus 로고    scopus 로고
    • AACE/AAES medical/surgical guidelines for clinical practice:Management of thyroid carcinoma
    • Task Force TC
    • Task Force TC. 2001. AACE/AAES medical/surgical guidelines for clinical practice:Management of thyroid carcinoma. Endocr Pr, 7:203-20.
    • (2001) Endocr Pr , vol.7 , pp. 203-220
  • 110
    • 15644367081 scopus 로고
    • Outcome after treatment of high-risk papillary and non- Hürthle-cell follicular thyroid carcinoma
    • Taylor T, Specker B, Robbins J, et al. 1989. Outcome after treatment of high-risk papillary and non- Hürthle-cell follicular thyroid carcinoma. Ann Int Med, 129:622-7.
    • (1989) Ann Int Med , vol.129 , pp. 622-627
    • Taylor, T.1    Specker, B.2    Robbins, J.3
  • 111
    • 0027964357 scopus 로고
    • Combined doxorubicin, hyperfractionated radiotherapy, and surgery in anaplastic thyroid carcinoma
    • Tennvall J, Lundell G, Hallquist A, et al. 1994. Combined doxorubicin, hyperfractionated radiotherapy, and surgery in anaplastic thyroid carcinoma. Cancer, 74:1348-54.
    • (1994) Cancer , vol.74 , pp. 1348-1354
    • Tennvall, J.1    Lundell, G.2    Hallquist, A.3
  • 112
    • 0034986658 scopus 로고    scopus 로고
    • AACE/AAES medical/surgical guidelines for clinical practice:management of thyroid carcinoma. American Association of Clinical Endocrinologists. American College of Endocrinology
    • Thyroid Carcinoma Task Force
    • Thyroid Carcinoma Task Force. 2001. AACE/AAES medical/surgical guidelines for clinical practice:management of thyroid carcinoma. American Association of Clinical Endocrinologists. American College of Endocrinology. Endocr Pract, 7:202-20.
    • (2001) Endocr Pract , vol.7 , pp. 202-220
  • 113
    • 33745136727 scopus 로고    scopus 로고
    • B-RAF mutations in the etiopathogenesis, diagnosis, and prognosis of thyroid carcinomas
    • Trovisco V, Soares P, Sobrinho-Simoes M. 2006. B-RAF mutations in the etiopathogenesis, diagnosis, and prognosis of thyroid carcinomas. Hum Pathol, 37:781-6.
    • (2006) Hum Pathol , vol.37 , pp. 781-786
    • Trovisco, V.1    Soares, P.2    Sobrinho-Simoes, M.3
  • 114
    • 0032622434 scopus 로고    scopus 로고
    • The current management of thyroid cancer
    • Udelsman R, Chen H. 1999. The current management of thyroid cancer. Adv Surg, 33:1-27.
    • (1999) Adv Surg , vol.33 , pp. 1-27
    • Udelsman, R.1    Chen, H.2
  • 115
    • 33748132208 scopus 로고    scopus 로고
    • In-vivo activation of Raf-1 inhibits tumor growth and development in a xenograft model of human medullary thyroid cancer
    • Vaccaro A, Chen H, Kunnimalaiyaan M, et al. 2006. In-vivo activation of Raf-1 inhibits tumor growth and development in a xenograft model of human medullary thyroid cancer. Anticancer Drugs, 17:849-53.
    • (2006) Anticancer Drugs , vol.17 , pp. 849-853
    • Vaccaro, A.1    Chen, H.2    Kunnimalaiyaan, M.3
  • 116
    • 18144392678 scopus 로고    scopus 로고
    • ZD6474 suppresses oncogenic RET isoforms in a Drosphila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma
    • Vidal M, Wells S, Ryan A. 2005. ZD6474 suppresses oncogenic RET isoforms in a Drosphila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma. Cancer Res, 65:3538-41.
    • (2005) Cancer Res , vol.65 , pp. 3538-3541
    • Vidal, M.1    Wells, S.2    Ryan, A.3
  • 117
    • 0037102369 scopus 로고    scopus 로고
    • ZD6474 inhibits vascular endothelial growth factor signaling, angiongenesis, and tumor growth following oral administration
    • Wedge SR, Ogilvie DJ, Dukes M, et al. 2002. ZD6474 inhibits vascular endothelial growth factor signaling, angiongenesis, and tumor growth following oral administration. Cancer Res, 62:4645-55.
    • (2002) Cancer Res , vol.62 , pp. 4645-4655
    • Wedge, S.R.1    Ogilvie, D.J.2    Dukes, M.3
  • 118
    • 40849118632 scopus 로고    scopus 로고
    • Vandetanib in metastatic hereditary medullary thyroid cancer:follow-up results of an open-label phase II trial [abstract]
    • Abst 6018
    • Wells S, Gosnell J, Gagel RF, et al. 2007. Vandetanib in metastatic hereditary medullary thyroid cancer:follow-up results of an open-label phase II trial [abstract]. Proc Am Soc Clin Oncol. Abst 6018.
    • (2007) Proc Am Soc Clin Oncol
    • Wells, S.1    Gosnell, J.2    Gagel, R.F.3
  • 119
    • 34248202225 scopus 로고    scopus 로고
    • Central lymph node dissection in differentiated thyroid cancer
    • White ML, Gauger PG, Doherty G. 2007. Central lymph node dissection in differentiated thyroid cancer. World J Surg, 31:895-904.
    • (2007) World J Surg , vol.31 , pp. 895-904
    • White, M.L.1    Gauger, P.G.2    Doherty, G.3
  • 120
    • 0025091281 scopus 로고
    • Ablative radioactive iodine therapy for apparently localized thyroid carcinoma:a decision analytic perspective
    • Wong JB, Kaplan MM, Meyer KB, et al. 1990. Ablative radioactive iodine therapy for apparently localized thyroid carcinoma:a decision analytic perspective. Endocrinol Metab Clin North Am, 19:741-60.
    • (1990) Endocrinol Metab Clin North Am , vol.19 , pp. 741-760
    • Wong, J.B.1    Kaplan, M.M.2    Meyer, K.B.3
  • 121
    • 21244457181 scopus 로고    scopus 로고
    • BRAF mutation in thyroid cancer
    • Xing M. 2005. BRAF mutation in thyroid cancer. Endocr-Relat Cancer, 12:245-62.
    • (2005) Endocr-Relat Cancer , vol.12 , pp. 245-262
    • Xing, M.1
  • 122
    • 33846849604 scopus 로고    scopus 로고
    • Differentiated thyroid cancer cell invasion is regulated through epidermal growth factor receptor-dependent activation of matrix metalloproteinase (MMP)-2/ gelatinase A
    • Yeh MW, Rougier JP, Park JW, et al. 2006. Differentiated thyroid cancer cell invasion is regulated through epidermal growth factor receptor-dependent activation of matrix metalloproteinase (MMP)-2/ gelatinase A. Endocr-Relat Cancer, 13:1173-83.
    • (2006) Endocr-Relat Cancer , vol.13 , pp. 1173-1183
    • Yeh, M.W.1    Rougier, J.P.2    Park, J.W.3
  • 123
    • 22844440114 scopus 로고    scopus 로고
    • Notch signaling in the mammalian central nervous system:Insights from mouse mutants
    • Yoon K, Gaiano N. 2005. Notch signaling in the mammalian central nervous system:Insights from mouse mutants. Nat Neurosci, 8:709-15.
    • (2005) Nat Neurosci , vol.8 , pp. 709-715
    • Yoon, K.1    Gaiano, N.2
  • 124
    • 0018951214 scopus 로고
    • Pure follicular thyroid carcinoma:impact of therapy in 214 patients
    • Young RL, Mazzaferri EL, Rahe AJ, et al. 1980. Pure follicular thyroid carcinoma:impact of therapy in 214 patients. J Nuclear Med, 21:733-7.
    • (1980) J Nuclear Med , vol.21 , pp. 733-737
    • Young, R.L.1    Mazzaferri, E.L.2    Rahe, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.