-
1
-
-
0037260139
-
Cancer statistics, 2003
-
Jemal A, Murray T, Samuels A, Ghafoor A, Ward E, Thun MJ. Cancer statistics, 2003. CA Cancer J Clin 2003;53:5-26.
-
(2003)
CA Cancer J Clin
, vol.53
, pp. 5-26
-
-
Jemal, A.1
Murray, T.2
Samuels, A.3
Ghafoor, A.4
Ward, E.5
Thun, M.J.6
-
2
-
-
0034644473
-
Signaling to chromatin through histone modifications
-
Cheung P, Allis CD, Sassone-Corsi P. Signaling to chromatin through histone modifications. Cell 2000;103:263-71.
-
(2000)
Cell
, vol.103
, pp. 263-271
-
-
Cheung, P.1
Allis, C.D.2
Sassone-Corsi, P.3
-
3
-
-
0035839136
-
Translating the histone code
-
Jenuwein T, Allis CD. Translating the histone code. Science 2001;293:1074-80.
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
4
-
-
0030069082
-
Deviant nucleosomes: The functional specialization of chromatin
-
Wolffe AP, Pruss D. Deviant nucleosomes: the functional specialization of chromatin. Trends Genet 1996;12:58-62.
-
(1996)
Trends Genet
, vol.12
, pp. 58-62
-
-
Wolffe, A.P.1
Pruss, D.2
-
5
-
-
0033848849
-
Histone acetylation and an epigenetic code
-
Turner BM. Histone acetylation and an epigenetic code. Bioessays 2000;22:836-45.
-
(2000)
Bioessays
, vol.22
, pp. 836-845
-
-
Turner, B.M.1
-
6
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl BD, Allis CD. The language of covalent histone modifications. Nature 2000;403:41-5.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
7
-
-
0000481738
-
Chromatin organisation and human disease
-
Urnov FD, Wolffe AP. Chromatin organisation and human disease. Emerg Ther Targets 2000;4:665-85.
-
(2000)
Emerg Ther Targets
, vol.4
, pp. 665-685
-
-
Urnov, F.D.1
Wolffe, A.P.2
-
8
-
-
0034252183
-
Histone acetylation modifiers in the pathogenesis of malignant disease
-
Mahlknecht U, Hoelzer D. Histone acetylation modifiers in the pathogenesis of malignant disease. Mol Med 2000;6:623-44.
-
(2000)
Mol Med
, vol.6
, pp. 623-644
-
-
Mahlknecht, U.1
Hoelzer, D.2
-
9
-
-
0034045040
-
Histone deacetylases, transcriptional control, and cancer
-
Cress WD, Seto E. Histone deacetylases, transcriptional control, and cancer. J Cell Physiol 2000;184:1-16.
-
(2000)
J Cell Physiol
, vol.184
, pp. 1-16
-
-
Cress, W.D.1
Seto, E.2
-
10
-
-
0035755974
-
Histone deacetylases and cancer: Causes and therapies
-
Marks P, Rifkind RA, Richon VM, Breslow R, Miller T, Kelly WK. Histone deacetylases and cancer: causes and therapies. Nat Rev Cancer 2001;1:194-202.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 194-202
-
-
Marks, P.1
Rifkind, R.A.2
Richon, V.M.3
Breslow, R.4
Miller, T.5
Kelly, W.K.6
-
11
-
-
0034596309
-
Histone deacetylase inhibitors: Inducers of differentiation or apoptosis of transformed cells
-
Marks PA, Richon VM, Rifkind RA. Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells. J Natl Cancer Inst 2000;92:1210-6.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1210-1216
-
-
Marks, P.A.1
Richon, V.M.2
Rifkind, R.A.3
-
13
-
-
0035046529
-
Histone deacetylase inhibitors : Development of suberoylanilide hydroxamic acid (SAHA) for the treatment of cancers
-
Richon VM, Zhou X, Rifkind RA, Marks PA. Histone deacetylase inhibitors : development of suberoylanilide hydroxamic acid (SAHA) for the treatment of cancers. Blood Cells Mol Dis 2001;27:260-4.
-
(2001)
Blood Cells Mol Dis
, vol.27
, pp. 260-264
-
-
Richon, V.M.1
Zhou, X.2
Rifkind, R.A.3
Marks, P.A.4
-
14
-
-
0032539890
-
A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases
-
Richon VM, Emiliani S, Verdin E, et al. A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases. Proc Natl Acad Sci U S A 1998;95:3003-7.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 3003-3007
-
-
Richon, V.M.1
Emiliani, S.2
Verdin, E.3
-
15
-
-
0036301281
-
Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms
-
Sandor V, Bakke S, Robey RW, et al. Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms. Clin Cancer Res 2002;8:718-28.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 718-728
-
-
Sandor, V.1
Bakke, S.2
Robey, R.W.3
-
16
-
-
0033199896
-
Hybrid polar histone deacetylase inhibitor induces apoptosis and CD95/CD95 ligand expression in human neuroblastoma
-
Glick RD, Swendeman SL, Coffey DC, et al. Hybrid polar histone deacetylase inhibitor induces apoptosis and CD95/CD95 ligand expression in human neuroblastoma. Cancer Res 1999;59:4392-9.
-
(1999)
Cancer Res
, vol.59
, pp. 4392-4399
-
-
Glick, R.D.1
Swendeman, S.L.2
Coffey, D.C.3
-
17
-
-
0034665124
-
Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo
-
Butler LM, Agus DB, Scher HI, et al. Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo. Cancer Res 2000;60:5165-70.
-
(2000)
Cancer Res
, vol.60
, pp. 5165-5170
-
-
Butler, L.M.1
Agus, D.B.2
Scher, H.I.3
-
18
-
-
0033539092
-
Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors
-
Finnin MS, Donigian JR, Cohen A, et al. Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors. Nature 1999;401:188-93.
-
(1999)
Nature
, vol.401
, pp. 188-193
-
-
Finnin, M.S.1
Donigian, J.R.2
Cohen, A.3
-
20
-
-
0034706893
-
WAF1/CIP1 promoter independent of p53 by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through the Sp1 sites
-
WAF1/CIP1 promoter independent of p53 by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through the Sp1 sites. Oncogene 2000;19:5712-9.
-
(2000)
Oncogene
, vol.19
, pp. 5712-5719
-
-
Huang, L.1
Sowa, Y.2
Sakai, T.3
Pardee, A.B.4
-
22
-
-
12444321545
-
Phase I clinical trial of histone deacetylase inhibitor: Suberoylanilide hydroxamic acid administered intravenously
-
Kelly WK, Richon VM, O'Connor O, et al. Phase I clinical trial of histone deacetylase inhibitor: suberoylanilide hydroxamic acid administered intravenously. Clin Cancer Res 2003;9:3578-88.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 3578-3588
-
-
Kelly, W.K.1
Richon, V.M.2
O'Connor, O.3
-
23
-
-
12444310200
-
Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), orally administered has good bioavailability and biologic activity
-
Kelly WK, Richon VM, Curley T, et al. Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), orally administered has good bioavailability and biologic activity. In: American Society of Clinical Oncology Annual Meeting Proceedings; 2002. p. 6b.
-
(2002)
American Society of Clinical Oncology Annual Meeting Proceedings
-
-
Kelly, W.K.1
Richon, V.M.2
Curley, T.3
-
25
-
-
0030984102
-
Identification of rapid turnover transcripts overexpressed in thyroid tumors and thyroid cancer cell lines: Use of a targeted differential RNA display method to select for mRNA subsets
-
Gonsky R, Knauf JA, Elisei R, Wang JW, Su S, Fagin JA. Identification of rapid turnover transcripts overexpressed in thyroid tumors and thyroid cancer cell lines: use of a targeted differential RNA display method to select for mRNA subsets. Nucleic Acids Res 1997;25:3823-31.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 3823-3831
-
-
Gonsky, R.1
Knauf, J.A.2
Elisei, R.3
Wang, J.W.4
Su, S.5
Fagin, J.A.6
-
26
-
-
0027455042
-
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
-
Fagin JA, Matsuo K, Karmakar A, Chen DL, Tang SH, Koeffler HP. High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas. J Clin Invest 1993;91:179-84.
-
(1993)
J Clin Invest
, vol.91
, pp. 179-184
-
-
Fagin, J.A.1
Matsuo, K.2
Karmakar, A.3
Chen, D.L.4
Tang, S.H.5
Koeffler, H.P.6
-
27
-
-
0024996768
-
Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A
-
Yoshida M, Kijima M, Akita M, Beppu T. Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A. J Biol Chem 1990;265:17174-9.
-
(1990)
J Biol Chem
, vol.265
, pp. 17174-17179
-
-
Yoshida, M.1
Kijima, M.2
Akita, M.3
Beppu, T.4
-
28
-
-
0035437171
-
TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: Therapeutic applications
-
Mitsiades CS, Treon SP, Mitsiades N, et al. TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applications. Blood 2001;98:795-804.
-
(2001)
Blood
, vol.98
, pp. 795-804
-
-
Mitsiades, C.S.1
Treon, S.P.2
Mitsiades, N.3
-
29
-
-
0035266139
-
Induction of ETS-1 and ETS-2 transcription factors is required for thyroid cell transformation
-
de Nigris F, Mega T, Berger N, et al. Induction of ETS-1 and ETS-2 transcription factors is required for thyroid cell transformation. Cancer Res 2001;61:2267-75.
-
(2001)
Cancer Res
, vol.61
, pp. 2267-2275
-
-
De Nigris, F.1
Mega, T.2
Berger, N.3
-
30
-
-
0034523818
-
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
-
Korsmeyer SJ, Wei MC, Saito M, Weiler S, Oh KJ, Schlesinger PH. Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. Cell Death Differ 2000;7:1166-73.
-
(2000)
Cell Death Differ
, vol.7
, pp. 1166-1173
-
-
Korsmeyer, S.J.1
Wei, M.C.2
Saito, M.3
Weiler, S.4
Oh, K.J.5
Schlesinger, P.H.6
-
31
-
-
0036776260
-
A histone deacetylase inhibitor enhances killing of undifferentiated thyroid carcinoma cells by p53 gene therapy
-
Imanishi R, Ohtsuru A, Iwamatsu M, et al. A histone deacetylase inhibitor enhances killing of undifferentiated thyroid carcinoma cells by p53 gene therapy. J Clin Endocrinol Metab 2002;87:4821-4.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 4821-4824
-
-
Imanishi, R.1
Ohtsuru, A.2
Iwamatsu, M.3
-
32
-
-
0034913856
-
Low concentrations of the histone deacetylase inhibitor, depsipeptide (FR901228), increase expression of the Na(+)/l(-) symporter and iodine accumulation in poorly differentiated thyroid carcinoma cells
-
Kitazono M, Robey R, Zhan Z, et al. Low concentrations of the histone deacetylase inhibitor, depsipeptide (FR901228), increase expression of the Na(+)/l(-) symporter and iodine accumulation in poorly differentiated thyroid carcinoma cells. J Clin Endocrinol Metab 2001;86:3430-5.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 3430-3435
-
-
Kitazono, M.1
Robey, R.2
Zhan, Z.3
-
33
-
-
0035023260
-
Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in anaplastic thyroid cancer cells
-
Greenberg VL, Williams JM, Cogswell JP, Mendenhall M, Zimmer SG. Histone deacetylase inhibitors promote apoptosis and differential cell cycle arrest in anaplastic thyroid cancer cells.Thyroid 2001;11:315-25.
-
(2001)
Thyroid
, vol.11
, pp. 315-325
-
-
Greenberg, V.L.1
Williams, J.M.2
Cogswell, J.P.3
Mendenhall, M.4
Zimmer, S.G.5
-
34
-
-
0035328528
-
The histone deacetylase inhibitor, CBHA, inhibits growth of human neuroblastoma xenografts in vivo, alone and synergistically with all-trans retinoic acid
-
Coffey DC, Kutko MC, Glick RD, et al. The histone deacetylase inhibitor, CBHA, inhibits growth of human neuroblastoma xenografts in vivo, alone and synergistically with all-trans retinoic acid. Cancer Res 2001;61:3591-4.
-
(2001)
Cancer Res
, vol.61
, pp. 3591-3594
-
-
Coffey, D.C.1
Kutko, M.C.2
Glick, R.D.3
-
35
-
-
0026792908
-
Role of p53 mutations in endocrine tumorigenesis: Mutation detection by polymerase chain reaction-single strand conformation polymorphism
-
Yoshimoto K, Iwahana H, Fukuda A, Sano T, Saito S, Itakura M. Role of p53 mutations in endocrine tumorigenesis: mutation detection by polymerase chain reaction-single strand conformation polymorphism. Cancer Res 1992;52:5061-4.
-
(1992)
Cancer Res
, vol.52
, pp. 5061-5064
-
-
Yoshimoto, K.1
Iwahana, H.2
Fukuda, A.3
Sano, T.4
Saito, S.5
Itakura, M.6
-
36
-
-
0033604457
-
L, c-Jun, and p21CIP1, but independent of p53
-
L, c-Jun, and p21CIP1, but independent of p53. Oncogene 1999;18:7016-25.
-
(1999)
Oncogene
, vol.18
, pp. 7016-7025
-
-
Vrana, J.A.1
Decker, R.H.2
Johnson, C.R.3
-
37
-
-
0037589018
-
Molecular sequelae of histone deacetylase inhibition in human malignant B cells
-
Mitsiades N, Mitsiades CS, Richardson PG, et al. Molecular sequelae of histone deacetylase inhibition in human malignant B cells. Blood 2003;101:4055-62.
-
(2003)
Blood
, vol.101
, pp. 4055-4062
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Richardson, P.G.3
-
38
-
-
0035845541
-
The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species
-
Ruefli AA, Ausserlechner MJ, Bernhard D, et al. The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species. Proc Natl Acad Sci U S A 2001;98:10833-8.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10833-10838
-
-
Ruefli, A.A.1
Ausserlechner, M.J.2
Bernhard, D.3
-
39
-
-
0038485588
-
Role of caspases, bid and p53 in the apoptotic response triggered by histone deacetylase inhibitors TSA and SAHA
-
Henderson C, Mizzau M, Paroni G, Maestro R, Schneider C, Brancolini C. Role of caspases, bid and p53 in the apoptotic response triggered by histone deacetylase inhibitors TSA and SAHA. J Biol Chem 2003;278:12579-89.
-
(2003)
J Biol Chem
, vol.278
, pp. 12579-12589
-
-
Henderson, C.1
Mizzau, M.2
Paroni, G.3
Maestro, R.4
Schneider, C.5
Brancolini, C.6
-
40
-
-
0034297220
-
Suberoylanilide hydroxamic acid as a potential therapeutic agent for human breast cancer treatment
-
Huang L, Pardee AB. Suberoylanilide hydroxamic acid as a potential therapeutic agent for human breast cancer treatment. Mol Med 2000;6:849-66.
-
(2000)
Mol Med
, vol.6
, pp. 849-866
-
-
Huang, L.1
Pardee, A.B.2
-
41
-
-
9144220841
-
Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications
-
Mitsiades CS, Mitsiades NS, McMullan CJ, et al. Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications. Proc Natl Acad Sci U S A 2004;101:540-5.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 540-545
-
-
Mitsiades, C.S.1
Mitsiades, N.S.2
McMullan, C.J.3
-
42
-
-
0032910169
-
Apoptosis control by death and decoy receptors
-
Ashkenazi A, Dixit VM. Apoptosis control by death and decoy receptors. Curr Opin Cell Biol 1999;11:255-60.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 255-260
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
43
-
-
0032526268
-
Apoptosis signaling by death receptors
-
Schulze-Osthoff K, Ferrari D, Los M, Wesselborg S, Peter ME. Apoptosis signaling by death receptors. Eur J Biochem 1998;254:439-59.
-
(1998)
Eur J Biochem
, vol.254
, pp. 439-459
-
-
Schulze-Osthoff, K.1
Ferrari, D.2
Los, M.3
Wesselborg, S.4
Peter, M.E.5
-
44
-
-
0032575752
-
Mitochondria and apoptosis
-
Green DR, Reed JC. Mitochondria and apoptosis. Science 1998;281:1309-12.
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
45
-
-
9344222195
-
Bcl-2 interrupts the ceramide-mediated pathway of cell death
-
Zhang J, Alter N, Reed JC, Borner C, Obeid LM, Hannun YA. Bcl-2 interrupts the ceramide-mediated pathway of cell death. Proc Natl Acad Sci U S A 1996;93:5325-8.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5325-5328
-
-
Zhang, J.1
Alter, N.2
Reed, J.C.3
Borner, C.4
Obeid, L.M.5
Hannun, Y.A.6
-
46
-
-
0027318190
-
Bcl-2 inhibits death of central neural cells induced by multiple agents
-
Zhong LT, Sarafian T, Kane DJ, et al. Bcl-2 inhibits death of central neural cells induced by multiple agents. Proc Natl Acad Sci U S A 1993;90:4533-7.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 4533-4537
-
-
Zhong, L.T.1
Sarafian, T.2
Kane, D.J.3
-
47
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
Scaffidi C, Fulda S, Srinivasan A, et al. Two CD95 (APO-1/Fas) signaling pathways. EMBO J 1998;17:1675-87.
-
(1998)
EMBO J
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
-
48
-
-
0042855004
-
The role of apoptosis-inducing receptors of the tumor necrosis factor family in thyroid cancer
-
Mitsiades CS, Poulaki V, Mitsiades N. The role of apoptosis-inducing receptors of the tumor necrosis factor family in thyroid cancer. J Endocrinol 2003;178:205-16.
-
(2003)
J Endocrinol
, vol.178
, pp. 205-216
-
-
Mitsiades, C.S.1
Poulaki, V.2
Mitsiades, N.3
-
49
-
-
0029444443
-
The immune response to papillary thyroid cancer
-
Baker JR Jr. The immune response to papillary thyroid cancer. J Clin Endocrinol Metab 1995;80:3419-20.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 3419-3420
-
-
Baker Jr., J.R.1
-
50
-
-
0033883775
-
Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand
-
Mitsiades N, Poulaki V, Tseleni-Balafouta S, Koutras DA, Stamenkovic I. Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand. Cancer Res 2000;60:4122-9.
-
(2000)
Cancer Res
, vol.60
, pp. 4122-4129
-
-
Mitsiades, N.1
Poulaki, V.2
Tseleni-Balafouta, S.3
Koutras, D.A.4
Stamenkovic, I.5
-
51
-
-
0036966429
-
Regulation of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in thyroid carcinoma cells
-
Poulaki V, Mitsiades CS, Kotoula V, et al. Regulation of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in thyroid carcinoma cells. Am J Pathol 2002;161:643-54.
-
(2002)
Am J Pathol
, vol.161
, pp. 643-654
-
-
Poulaki, V.1
Mitsiades, C.S.2
Kotoula, V.3
-
52
-
-
0037905957
-
A phase I clinical trial of an oral formulation of the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA)
-
Kelly W, O'Connor O, Richon VM, et al. A phase I clinical trial of an oral formulation of the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA). Eur J Cancer 2002;38:88.
-
(2002)
Eur J Cancer
, vol.38
, pp. 88
-
-
Kelly, W.1
O'Connor, O.2
Richon, V.M.3
|