LIM kinase-2 induces programmed necrotic neuronal death via dysfunction of DRP1-mediated mitochondrial fission

Cell Death and Differentiation

Volumn 21, Issue 7, 2014, Pages 1036-1049

  Kim, J E ^a   Ryu, H J ^a   Kim, M J ^a   Kang, T C ^a  

^a Hallym University   (South Korea)

Author keywords

cyclin D1 cyclin dependent kinase 4; dynamic related protein 1; LIM kinase 2; necrotic neuronal death; seizure

Indexed keywords

CASPASE 3; COFILIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; DYNAMIC RELATED PROTEIN 1; LIM KINASE; PROTEIN; PROTEIN P27; RHO KINASE; UNCLASSIFIED DRUG; CCND1 PROTEIN, RAT; CDKN1B PROTEIN, RAT; CYCLIN DEPENDENT KINASE INHIBITOR 1B; DRP1 PROTEIN, RAT; DYNAMIN; LIMK2 PROTEIN, RAT; PROTEIN SERINE THREONINE KINASE; RIP1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; EPILEPTIC STATE; MALE; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL FISSION; MITOCHONDRION; NERVE CELL; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; ANIMAL; ENZYMOLOGY; GENE EXPRESSION; HIPPOCAMPAL CA1 REGION; METABOLISM; NECROSIS; PATHOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; CA1 REGION, HIPPOCAMPAL; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DYNAMINS; GENE EXPRESSION; LIM KINASES; MALE; MITOCHONDRIAL DYNAMICS; NECROSIS; PROTEIN-SERINE-THREONINE KINASES; RATS, SPRAGUE-DAWLEY; RHO-ASSOCIATED KINASES; STATUS EPILEPTICUS;

EID: 84902280177     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2014.17     Document Type: Article

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