Pyridoxal-5'-phosphate phosphatase/chronophin induces astroglial apoptosis via actin-depolymerizing factor/cofilin system in the rat brain following status epilepticus

GLIA

Volumn 58, Issue 16, 2010, Pages 1937-1948

  Kim, Ji Eun ^a   Ryu, Hea Jin ^a   Kim, Min Ju ^a   Kim, Dae Won ^a   Kwon, Oh Shin ^b   Choi, Soo Young ^a   Kang, Tae Cheon ^a  

^a Hallym University   (South Korea)

^b Kyungpook National University   (South Korea)

Author keywords

ADF colin; AIF; Apoptosis; Astro cytes; PLPP CIN; Status epilepticus

Indexed keywords

ACTIN DEPOLYMERIZING FACTOR; APOPTOSIS INDUCING FACTOR; CHRONOPHIN; COFILIN; PHOSPHATASE; PYRIDOXAL 5 PHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN; CELL DAMAGE; CELL DEATH; CONTROLLED STUDY; DENTATE GYRUS; EPILEPTIC STATE; MACROGLIA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION;

ACTIN DEPOLYMERIZING FACTORS; ANIMALS; APOPTOSIS; ASTROCYTES; CELL NUCLEUS; CYTOPLASM; DENTATE GYRUS; MALE; MITOCHONDRIA; PHOSPHORIC MONOESTER HYDROLASES; RATS; RATS, SPRAGUE-DAWLEY; STATUS EPILEPTICUS;

EID: 78649413031     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.21063     Document Type: Article

References (35)

1. Amano T, Tanabe K, Eto T, Narumiya S, Mizuno K. 2001. LIM-kinase 2 induces formation of stress fibers, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505. Biochem J 354:149-159.
2. Arber S, Barbayannis FA, Hanser H, Schneider C, Stanyon CA, Bernard O, Caroni P. 1998. Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase. Nature 393:805-809.
3. Bamburg JR. 1999. Proteins of the ADF/cofilin family: Essential regulators of actin dynamics. Annu Rev Cell Dev Biol 15:185-230.
4. Bamburg JR, McGough A, Ono S. 1999. Putting a new twist on actin: ADF/cofilins modulate actin dynamics. Trends Cell Biol 9:364-370.
5. Candé C, Cecconi F, Dessen P, Kroemer G. 2002. Apoptosis-inducing factor (AIF): Key to the conserved caspase-independent pathways of cell death? J Cell Sci 115:4727-4734.
6. Candé C, Vahsen N, Kouranti I, Schmitt E, Daugas E, Spahr C, Luban J, Kroemer RT, Giordanetto F, Garrido C, Penninger JM, Kroemer G. 2004. AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis. Oncogne 23:1514-1521.
7. Cao G, Clark RS, Pei W, Yin W, Zhang F, Sun FY, Graham SH, Chen J. 2003. Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation. J Cereb Blood Flow Metab 23:1137-1150.
8. Chinta SJ, Rane A, Yadava N, Andersen JK, Nicholls DG, Polster BM. 2009. Reactive oxygen species regulation by AIF-and complex Idepleted brain mitochondria. Free Radic Biol Med 46:939-947.
9. Chua BT, Volbracht C, Tan KO, Li R, Yu VC, Li P. 2003. Mitochondrial translocation of cofilin is an early step in apoptosis induction. Nat Cell Biol 5:1083-1089.
10. Cregan SP, Dawson VI, Slack RS. 2004. Role of AIF in caspase-dependent and caspase-independent cell death. Oncogene 23:2785-2796.
11. Eguchi Y, Srinivasan A, Tomaselli KJ, Shimizu S, Tsujimoto Y. 1999. ATP dependent steps in apoptotic signal transduction. Cancer Res 59: 2174-2181.
12. García-Cáceres C, Lechuga-Sancho A, Argente J, Frago LM, Chowen JA. 2008. Death of hypothalamic astrocytes in poorly controlled diabetic rats is associated with nuclear translocation of apoptosis inducing factor. J Neuroendocrinol 20:1348-1360.
13. Gohla A, Birkenfeld J, Bokoch GM. 2005. Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics. Nat Cell Biol 7:21-29.
14. Gürer G, Gursoy-Ozdemir Y, Erdemli E, Can A, Dalkara T. 2009. Astrocytes are more resistant to focal cerebral ischemia than neurons and die by a delayed necrosis. Brain Pathol 19:630-641.
15. Jang YM, Kim DW, Kang TC, Won MH, Baek NI, Moon BJ, Choi SY, Kwon OS. 2003. Human pyridoxal phosphatase. Molecular cloning, functional expression, and tissue distribution. J Biol Chem 278: 50040-50046.
16. Joza N, Susin SA, Daugas E, Stanford WL, Cho SK, Li CY, Sasaki T, Elia AJ, Cheng HY, Ravagnan L, Ferri KF, Zamzami N, Wakeham A, Hakem R, Yoshida H, Kong YY, Mak TW, Zúñiga-Pflücker JC, Kroemer G, Penninger JM. 2001. Essential role of the mitochondrial apoptosisinducing factor in programmed cell death. Nature 410:549-554.
17. Kang TC, Kim DS, Kwak SE, Kim JE, Won MH, Kim DW, Choi SY, Kwon OS. 2006. Epileptogenic roles of astroglial death and regeneration in the dentate gyrus of experimental temporal lobe epilepsy. Glia 54:258-271.
18. Kim DS, Kim JE, Kwak SE, Choi KC, Kim DW, Kwon OS, Choi SY, Kang TC. 2008a. Spatiotemporal characteristics of astroglial death in the rat hippocampo-entorhinal complex following pilocarpine-induced status epilepticus. J Comp Neurol 511:581-598.
19. Kim JE, Kim DW, Kwak SE, Kwon OS, Choi SY, Kang TC. 2008b. Potential role of pyridoxal-5'-phosphate phosphatase/chronopin in epilepsy. Exp Neurol 211:128-140.
20. Kim JE, Kim DW, Kwak SE, Ryu HJ, Yeo SI, Kwon OS, Choi SY, Kang TC. 2009a. Pyridoxal-5'-phosphate phosphatase/chronophin inhibits long-term potentiation induction in the rat dentate gyrus. Hippocampus 19:1078-1089.
21. Kim JE, Kwak SE, Kang TC. 2009b. Upregulated TWIK-related acid-sensitive K1 channel-2 in neurons and perivascular astrocytes in the hippocampus of experimental temporal lobe epilepsy. Epilepsia 50:654-663.
22. Nare B, Allocco JJ, Kuningas R, Galuska S, Myers RW, Bednarek MA, Schmatz DM. 1999. Development of a scintillation proximity assay for histone deacetylase using a biotinylated peptide derived from histone-H4. Anal Biochem 267:390-396.
23. Oh YK, Shin KS, Kang SJ. 2006. AIF translocates to the nucleus in the spinal motor neurons in a mouse model of ALS. Neurosci Lett 406: 205-210.
24. Otera H, Ohsakaya S, Nagaura Z, Ishihara N, Mihara K. 2005. Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space. EMBO J 24:1375-1386.
25. Park J, Ryu J, Kim KA, Lee HJ, Bahn JH, Han K, Choi EY, Lee KS, Kwon HY, Choi SY. 2002. Mutational analysis of a human immunodeficiency virus type 1 Tat protein transduction domain which is required for delivery of an exogenous protein into mammalian cells. J Gen Virol 83:1173-1181.
26. Pendleton A, Pope B, Weeds A, Koffer A. 2003. Latrunculin B or ATP depletion induces cofilin-dependent translocation of actin into nuclei of mast cells. J Biol Chem 278:14394-14400.
27. Polster BM, Basanez G, Etxebarria A, Hardwick JM, Nicholls DG. 2005. Calpine I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria. J Biol Chem 280:6447-6454.
28. Qu Y, Mao M, Zhao F, Zhang L, Mu D. 2009. Proapoptotic role of human growth and transformation-dependent protein in the developing rat brain after hypoxia-ischemia. Stroke 40:2843-2848.
29. Susin SA, Lorenzo HK, Zamzami N, Marzo I, Snow BE, Brothers GM, Mangion J, Jacotot E, Costantini P, Loeffler M, Larochette N, Goodlett DR, Aebersold R, Siderovski DP, Penninger JM, Kroemer G. 1999. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397:441-446.
30. Theriot JA. 1997. Accelerating on a treadmill: ADF/cofilin promotes rapid actin filament turnover in the dynamic cytoskeleton. J Cell Biol 136:1165-1168.
31. Vander Heiden MG, Thompson CB. 1999. Bcl-2 proteins: Regulators of apoptosis or of mitochondrial homeostasis? Nat Cell Biol 1:E209-E216.
32. Wang G, Achim CL, Hamilton RL, Wiley CA, Soontornniyomkij V. 1999. Tyramide signal amplification method in multiple-label immunofluorescence confocal microscopy. Methods 18:459-464.
33. Yang N, Higuchi O, Ohashi K, Nagata K, Wada A, Kangawa K, Nishida E, Mizuno K. 1998. Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature 393:809-812.
34. Yuste VJ, Moubarak RS, Delettre C, Bras M, Sancho P, Robert N, d'Alayer J, Susin SA. 2005. Cysteine protease inhibition prevents mitochondrial apoptosis-inducing factor (AIF) release. Cell Death Differ 12:1445-1448.
35. Zhang X, Chen J, Graham SH, Du L, Kochanek PM, Draviam R, Guo F, Nathaniel PD, Szabó C, Watkins SC, Clark RS. 2002. Intranuclear localization of apoptosis-inducing factor (AIF) and large-scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite. J Neurochem 82:181-191