메뉴 건너뛰기




Volumn 123, Issue 23, 2014, Pages 3585-3595

C-Myc regulates expression of NKG2D ligands ULBP1/2/3 in AML and modulates their susceptibility to NK-mediated lysis

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CYTARABINE; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; NATURAL KILLER CELL RECEPTOR NKG2D; PROTEIN KINASE B; UL 16 BINDING PROTEIN 1; UL 16 BINDING PROTEIN 2; UL 16 BINDING PROTEIN 3; UNCLASSIFIED DRUG;

EID: 84902189225     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-11-536219     Document Type: Article
Times cited : (45)

References (53)
  • 1
    • 65549090436 scopus 로고    scopus 로고
    • Acute myelogenous leukemia
    • Shipley JL, Butera JN. Acute myelogenous leukemia. Exp Hematol. 2009;37(6):649-658.
    • (2009) Exp Hematol , vol.37 , Issue.6 , pp. 649-658
    • Shipley, J.L.1    Butera, J.N.2
  • 2
    • 0018741351 scopus 로고
    • Correlation between leukemic cell retention of 1-β-D- arabinofuranosylcytosine 5'-triphosphate and response to therapy
    • Rustum YM, Preisler HD. Correlation between leukemic cell retention of 1-beta-Darabinofuranosylcytosine 59-triphosphate and response to therapy. Cancer Res. 1979;39(1): 42-49. (Pubitemid 9090410)
    • (1979) Cancer Research , vol.39 , Issue.1 , pp. 42-49
    • Rustum, Y.M.1    Preisler, H.D.2
  • 3
    • 0030018203 scopus 로고    scopus 로고
    • Treatment of refractory AML
    • Estey E. Treatment of refractory AML. Leukemia. 1996;10(6):932-936. (Pubitemid 26235922)
    • (1996) Leukemia , vol.10 , Issue.6 , pp. 932-936
    • Estey, E.1
  • 4
    • 0030965033 scopus 로고    scopus 로고
    • A randomized phase II study on the effects of 5-Aza-29-deoxycytidine combined with either amsacrine or idarubicin in patients with relapsed acute leukemia: An EORTC Leukemia Cooperative Group phase II study 06893)
    • Willemze R, Suciu S, Archimbaud E, et al. A randomized phase II study on the effects of 5-Aza-29-deoxycytidine combined with either amsacrine or idarubicin in patients with relapsed acute leukemia: an EORTC Leukemia Cooperative Group phase II study (06893). Leukemia. 1997; 11(suppl 1):S24-S27.
    • (1997) Leukemia , vol.11 , Issue.SUPPL. 1
    • Willemze, R.1    Suciu, S.2    Archimbaud, E.3
  • 5
    • 84944369123 scopus 로고
    • Improved prospects for long-term survival in adults with acute myelogenous leukemia
    • DOI 10.1001/jama.248.19.2481
    • Keating MJ, McCredie KB, Bodey GP, Smith TL, Gehan E, Freireich EJ. Improved prospects for long-term survival in adults with acute myelogenous leukemia. JAMA. 1982;248(19): 2481-2486. (Pubitemid 13233970)
    • (1982) Journal of the American Medical Association , vol.248 , Issue.19 , pp. 2481-2486
    • Keating, M.J.1    McCredie, K.B.2    Bodey, G.P.3
  • 6
    • 84872087060 scopus 로고    scopus 로고
    • Sense and nonsense of high-dose cytarabine for acute myeloid leukemia
    • Löwenberg B. Sense and nonsense of high-dose cytarabine for acute myeloid leukemia. Blood. 2013;121(1):26-28.
    • (2013) Blood , vol.121 , Issue.1 , pp. 26-28
    • Löwenberg, B.1
  • 7
    • 0031156947 scopus 로고    scopus 로고
    • High-dose cytarabine and mitoxantrone as salvage therapy for refractory non-Hodgkin's lymphoma
    • Wang WS, Tzeng CH, Chiou TJ, et al. High-dose cytarabine and mitoxantrone as salvage therapy for refractory non-Hodgkin's lymphoma. Jpn J Clin Oncol. 1997;27(3):154-157.
    • (1997) Jpn J Clin Oncol , vol.27 , Issue.3 , pp. 154-157
    • Wang, W.S.1    Tzeng, C.H.2    Chiou, T.J.3
  • 9
    • 0031756061 scopus 로고    scopus 로고
    • Treatment of resistant disease
    • Schiller GJ. Treatment of resistant disease. Leukemia. 1998;12(suppl 1):S20-S24. (Pubitemid 28478999)
    • (1998) Leukemia , vol.12 , Issue.SUPPL. 1
    • Schiller, G.J.1
  • 10
    • 0031024850 scopus 로고    scopus 로고
    • Fas/APO-1 (CD95)-mediated cytotoxicity is responsible for the apoptotic cell death of leukaemic cells induced by interleukin-2-activated T cells
    • Komada Y, Zhou YW, Zhang XL, et al. Fas/APO-1 (CD95)-mediated cytotoxicity is responsible for the apoptotic cell death of leukaemic cells induced by interleukin-2-activated T cells. Br J Haematol. 1997;96(1):147-157.
    • (1997) Br J Haematol , vol.96 , Issue.1 , pp. 147-157
    • Komada, Y.1    Zhou, Y.W.2    Zhang, X.L.3
  • 11
    • 0030980994 scopus 로고    scopus 로고
    • Cytotoxic drugs, programmed cell death, and the immune system: Defining new roles in an old play
    • Debatin KM. Cytotoxic drugs, programmed cell death, and the immune system: defining new roles in an old play. J Natl Cancer Inst. 1997; 89(11):750-751.
    • (1997) J Natl Cancer Inst , vol.89 , Issue.11 , pp. 750-751
    • Debatin, K.M.1
  • 13
    • 0031178835 scopus 로고    scopus 로고
    • Bcl-2 Expression in Target Cells Leads to Functional Inhibition of Caspase-3 Protease Family in Human NK and Lymphokine-Activated Killer Cell Granule-Mediated Apoptosis
    • Renvoizé C, Roger R, Moulian N, Bertoglio J, Bréard J. Bcl-2 expression in target cells leads to functional inhibition of caspase-3 protease family in human NK and lymphokine-activated killer cell granule-mediated apoptosis. J Immunol. 1997; 159(1):126-134. (Pubitemid 127493693)
    • (1997) Journal of Immunology , vol.159 , Issue.1 , pp. 126-134
    • Renvoize, C.1    Roger, R.2    Moulian, N.3    Bertoglio, J.4    Breard, J.5
  • 14
    • 0030656234 scopus 로고    scopus 로고
    • Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells
    • Friesen C, Fulda S, Debatin KM. Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells. Leukemia. 1997;11(11): 1833-1841. (Pubitemid 27485127)
    • (1997) Leukemia , vol.11 , Issue.11 , pp. 1833-1841
    • Friesen, C.1    Fulda, S.2    Debatin, K.-M.3
  • 15
    • 0033013231 scopus 로고    scopus 로고
    • Chemotherapeutic drugs sensitize pre-B ALL cells for CD95- and cytotoxic T-lymphocyte-mediated apoptosis
    • Posovszky C, Friesen C, Herr I, Debatin KM. Chemotherapeutic drugs sensitize pre-B ALL cells for CD95-and cytotoxic T-lymphocyte-mediatedapoptosis. Leukemia. 1999;13(3):400-409. (Pubitemid 29108079)
    • (1999) Leukemia , vol.13 , Issue.3 , pp. 400-409
    • Posovszky, C.1    Friesen, C.2    Herr, I.3    Debatin, K.-M.4
  • 16
    • 0033012524 scopus 로고    scopus 로고
    • Decreased sensitivity of drug-resistant cells towards T cell cytotoxicity
    • Classen CF, Fulda S, Friesen C, Debatin KM. Decreased sensitivity of drug-resistant cells towards T cell cytotoxicity. Leukemia. 1999;13(3): 410-418. (Pubitemid 29108080)
    • (1999) Leukemia , vol.13 , Issue.3 , pp. 410-418
    • Classen, C.F.1    Fulda, S.2    Friesen, C.3    Debatin, K.-M.4
  • 17
    • 0037762891 scopus 로고    scopus 로고
    • Natural killer resistance of a drug-resistant leukemia cell line, mediated by up-regulation of HLA class I expression
    • Classen CF, Falk CS, Friesen C, Fulda S, Herr I, Debatin KM. Natural killer resistance of a drugresistant leukemia cell line, mediated by upregulation of HLA class I expression. Haematologica. 2003;88(5):509-521. (Pubitemid 36648440)
    • (2003) Haematologica , vol.88 , Issue.5 , pp. 509-521
    • Classen, C.F.1    Falk, C.S.2    Friesen, C.3    Fulda, S.4    Herr, I.5    Debatin, K.-M.6
  • 18
    • 0345256397 scopus 로고    scopus 로고
    • Altered conjugate formation and altered apoptosis of multidrug-resistant human leukemia cell line affects susceptibility to killing by activated natural killer (NK) cells
    • DOI 10.1002/ijc.11555
    • Treichel RS, Bunuan M, Hahn N, Wee K. Altered conjugate formation and altered apoptosis of multidrug-resistant human leukemia cell lineaffects susceptibility to killing by activated natural killer (NK) cells. Int J Cancer. 2004;108(1):78-85. (Pubitemid 37444447)
    • (2004) International Journal of Cancer , vol.108 , Issue.1 , pp. 78-85
    • Treichel, R.S.1    Bunuan, M.2    Hahn, N.3    Wee, K.4
  • 19
    • 79959826132 scopus 로고    scopus 로고
    • Prophylactic transfer of BCR-ABL-PR1-and WT1-reactive donor T cells after T cell-depleted allogeneic hematopoietic cell transplantation inpatients with chronic myeloid leukemia
    • Bornhäuser M, Thiede C, Platzbecker U, et al.Prophylactic transfer of BCR-ABL-, PR1-, and WT1-reactive donor T cells after T cell-depleted allogeneic hematopoietic cell transplantation inpatients with chronic myeloid leukemia. Blood. 2011;117(26):7174-7184.
    • (2011) Blood , vol.117 , Issue.26 , pp. 7174-7184
    • Bornhäuser, M.1    Thiede, C.2    Al Et, P.U.3
  • 20
    • 77949898005 scopus 로고    scopus 로고
    • NKAML: A pilot study to determine the safety and feasibility of haploidentical natural killer cell transplantation in childhood acute myeloid leukemia
    • Rubnitz JE, Inaba H, Ribeiro RC, et al. NKAML: a pilot study to determine the safety and feasibility of haploidentical natural killer cell transplantation in childhood acute myeloid leukemia. J Clin Oncol. 2010;28(6):955-959.
    • (2010) J Clin Oncol , vol.28 , Issue.6 , pp. 955-959
    • Rubnitz, J.E.1    Inaba, H.2    Ribeiro, R.C.3
  • 21
    • 20144388509 scopus 로고    scopus 로고
    • Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer
    • Miller JS, Soignier Y, Panoskaltsis-Mortari A, et al. Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer. Blood. 2005;105(8): 3051-3057.
    • (2005) Blood , vol.105 , Issue.8 , pp. 3051-3057
    • Miller, J.S.1    Soignier, Y.2    Panoskaltsis-Mortari, A.3
  • 23
    • 33748987908 scopus 로고    scopus 로고
    • Cancer despite immunosurveillance: Immunoselection and immunosubversion
    • DOI 10.1038/nri1936, PII NRI1936
    • Zitvogel L, Tesniere A, Kroemer G. Cancer despite immunosurveillance: immunoselection and immunosubversion. Nat Rev Immunol. 2006; 6(10):715-727. (Pubitemid 44453458)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.10 , pp. 715-727
    • Zitvogel, L.1    Tesniere, A.2    Kroemer, G.3
  • 24
    • 46949088469 scopus 로고    scopus 로고
    • Antiviral NK cell responses in HIV infection: I. NK cell receptor genes as determinants of HIV resistance and progression to AIDS
    • DOI 10.1189/jlb.0907650
    • Iannello A, Debbeche O, Samarani S, Ahmad A. Antiviral NK cell responses in HIV infection: I. NKcell receptor genes as determinants of HIVresistance and progression to AIDS. J Leukoc Biol. 2008;84(1):1-26. (Pubitemid 351960277)
    • (2008) Journal of Leukocyte Biology , vol.84 , Issue.1 , pp. 1-26
    • Iannello, A.1    Debbeche, O.2    Samarani, S.3    Ahmad, A.4
  • 26
    • 0031754827 scopus 로고    scopus 로고
    • Natural killer cells and their role in graft rejection
    • DOI 10.1016/S0952-7915(98)80219-7
    • Manilay JO, Sykes M. Natural killer cells and their role in graft rejection. Curr Opin Immunol. 1998; 10(5):532-538. (Pubitemid 28479184)
    • (1998) Current Opinion in Immunology , vol.10 , Issue.5 , pp. 532-538
    • Manilay, J.O.1    Sykes, M.2
  • 27
    • 67649995733 scopus 로고    scopus 로고
    • The innate natural killer cells in transplant rejection and tolerance induction
    • Kroemer A, Edtinger K, Li XC. The innate natural killer cells in transplant rejection and tolerance induction. Curr Opin Organ Transplant. 2008; 13(4):339-343.
    • (2008) Curr Opin Organ Transplant , vol.13 , Issue.4 , pp. 339-343
    • Kroemer, A.1    Edtinger, K.2    Li, X.C.3
  • 28
    • 34247595404 scopus 로고    scopus 로고
    • Prospects for theuse of NK cells in immunotherapy of human cancer
    • Ljunggren HG, Malmberg KJ. Prospects for theuse of NK cells in immunotherapy of human cancer. Nat Rev Immunol. 2007;7(5):329-339.
    • (2007) Nat Rev Immunol , vol.7 , Issue.5 , pp. 329-339
    • Ljunggren, H.G.1    Malmberg, K.J.2
  • 29
    • 33745567831 scopus 로고    scopus 로고
    • Self-tolerance of natural killer cells
    • DOI 10.1038/nri1863, PII N1863
    • Raulet DH, Vance RE. Self-tolerance of natural killer cells. Nat Rev Immunol. 2006;6(7):520-531. (Pubitemid 43980524)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.7 , pp. 520-531
    • Raulet, D.H.1    Vance, R.E.2
  • 30
    • 33646877669 scopus 로고    scopus 로고
    • Human natural killer cell development and biology
    • DOI 10.1016/j.blre.2005.10.001, PII S0268960X0500055X
    • Farag SS, Caligiuri MA. Human natural killer cell development and biology. Blood Rev. 2006;20(3): 123-137. (Pubitemid 43786166)
    • (2006) Blood Reviews , vol.20 , Issue.3 , pp. 123-137
    • Farag, S.S.1    Caligiuri, M.A.2
  • 31
    • 0033618504 scopus 로고    scopus 로고
    • Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
    • Bauer S, Groh V, Wu J, et al. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science. 1999;285(5428): 727-729.
    • (1999) Science , vol.285 , Issue.5428 , pp. 727-729
    • Bauer, S.1    Groh, V.2    Wu, J.3
  • 33
    • 1842526956 scopus 로고    scopus 로고
    • + T cells
    • DOI 10.1182/blood-2003-06-2125
    • Verneris MR, Karami M, Baker J, Jayaswal A, Negrin RS. Role of NKG2D signaling in the cytotoxicity of activated and expanded CD81 T cells. Blood. 2004;103(8):3065-3072. (Pubitemid 38451682)
    • (2004) Blood , vol.103 , Issue.8 , pp. 3065-3072
    • Verneris, M.R.1    Karami, M.2    Baker, J.3    Jayaswal, A.4    Negrin, R.S.5
  • 34
    • 53449094978 scopus 로고    scopus 로고
    • Activating NK cell receptor ligands are differentially expressed during progression to cervical cancer
    • Textor S, Dürst M, Jansen L, et al. Activating NK cell receptor ligands are differentially expressed during progression to cervical cancer. Int J Cancer. 2008;123(10):2343-2353.
    • (2008) Int J Cancer , vol.123 , Issue.10 , pp. 2343-2353
    • Textor, S.1    Dürst, M.2    Jansen, L.3
  • 35
    • 0036829733 scopus 로고    scopus 로고
    • Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: Analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity
    • Pende D, Rivera P, Marcenaro S, et al. Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity. Cancer Res. 2002;62(21): 6178-6186. (Pubitemid 35244469)
    • (2002) Cancer Research , vol.62 , Issue.21 , pp. 6178-6186
    • Pende, D.1    Rivera, P.2    Marcenaro, S.3    Chang, C.-C.4    Biassoni, R.5    Conte, R.6    Kubin, M.7    Cosman, D.8    Ferrone, S.9    Moretta, L.10    Moretta, A.11
  • 36
    • 0035054469 scopus 로고    scopus 로고
    • Role of NKG2D in tumor cell lysis mediated by human NK cells: Cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin
    • Pende D, Cantoni C, Rivera P, et al. Role of NKG2D in tumor cell lysis mediated by human NK cells: cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin. Eur J Immunol. 2001;31(4): 1076-1086.
    • (2001) Eur J Immunol , vol.31 , Issue.4 , pp. 1076-1086
    • Pende, D.1    Cantoni, C.2    Rivera, P.3
  • 37
    • 0142197631 scopus 로고    scopus 로고
    • Roles of the NKG2D immunoreceptor and its ligands
    • Raulet DH. Roles of the NKG2D immunoreceptor and its ligands. Nat Rev Immunol. 2003;3(10): 781-790. (Pubitemid 37328656)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.10 , pp. 781-790
    • Raulet, D.H.1
  • 38
    • 57349101681 scopus 로고    scopus 로고
    • Resistance to cytarabine induces the up-regulation of NKG2D ligands and enhances natural killer cell lysis of leukemic cells
    • Ogbomo H, Michaelis M, Klassert D, Doerr HW, Cinatl J Jr. Resistance to cytarabine induces the up-regulation of NKG2D ligands and enhances natural killer cell lysis of leukemic cells. Neoplasia. 2008;10(12):1402-1410.
    • (2008) Neoplasia , vol.10 , Issue.12 , pp. 1402-1410
    • Ogbomo, H.1    Michaelis, M.2    Klassert, D.3    Doerr, H.W.4    Cinatl Jr., J.5
  • 39
    • 65349131915 scopus 로고    scopus 로고
    • ATM-ATRdependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype
    • Soriani A, Zingoni A, Cerboni C, et al. ATM-ATRdependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype. Blood. 2009;113(15):3503-3511.
    • (2009) Blood , vol.113 , Issue.15 , pp. 3503-3511
    • Soriani, A.1    Zingoni, A.2    Cerboni, C.3
  • 41
    • 34447104224 scopus 로고    scopus 로고
    • Antigen-activated human T lymphocytes express cell-surface NKG2D ligands via an ATM/ATR-dependent mechanism and become susceptible to autologous NK-cell lysis
    • DOI 10.1182/blood-2006-10-052720
    • Cerboni C, Zingoni A, Cippitelli M, Piccoli M, Frati L, Santoni A. Antigen-activated human T lymphocytes express cell-surface NKG2D ligands via an ATM/ATR-dependent mechanism and become susceptible to autologous NK-cell lysis. Blood. 2007;110(2):606-615. (Pubitemid 47105399)
    • (2007) Blood , vol.110 , Issue.2 , pp. 606-615
    • Cerboni, C.1    Zingoni, A.2    Cippitelli, M.3    Piccoli, M.4    Frati, L.5    Santoni, A.6
  • 43
    • 84871566579 scopus 로고    scopus 로고
    • Valproic acid upregulates NKG2D ligand expression through an ERK-dependent mechanism and potentially enhances NK cell-mediated lysis of myeloma
    • Wu X, Tao Y, Hou J, Meng X, Shi J. Valproic acid upregulates NKG2D ligand expression through an ERK-dependent mechanism and potentially enhances NK cell-mediated lysis of myeloma. Neoplasia. 2012;14(12):1178-1189.
    • (2012) Neoplasia , vol.14 , Issue.12 , pp. 1178-1189
    • Wu, X.1    Tao, Y.2    Hou, J.3    Meng, X.4    Shi, J.5
  • 44
    • 80052793188 scopus 로고    scopus 로고
    • Human NK cells are alerted to induction of p53 in cancer cells by upregulation of the NKG2D ligands ULBP1 and ULBP2
    • Textor S, Fiegler N, Arnold A, Porgador A, Hofmann TG, Cerwenka A. Human NK cells are alerted to induction of p53 in cancer cells by upregulation of the NKG2D ligands ULBP1 and ULBP2. Cancer Res. 2011;71(18):5998-6009.
    • (2011) Cancer Res , vol.71 , Issue.18 , pp. 5998-6009
    • Textor, S.1    Fiegler, N.2    Arnold, A.3    Porgador, A.4    Hofmann, T.G.5    Cerwenka, A.6
  • 45
    • 79955761733 scopus 로고    scopus 로고
    • Post-transcriptional regulation of ULBP1 ligand for the activating immunoreceptor NKG2D involves 39 untranslated region
    • Himmelreich H, Mathys A, Wodnar-Filipowicz A, Kalberer CP. Post-transcriptional regulation of ULBP1 ligand for the activating immunoreceptor NKG2D involves 39 untranslated region. Hum Immunol. 2011;72(6):470-478.
    • (2011) Hum Immunol , vol.72 , Issue.6 , pp. 470-478
    • Himmelreich, H.1    Mathys, A.2    Wodnar-Filipowicz, A.3    Kalberer, C.P.4
  • 46
    • 24144443517 scopus 로고    scopus 로고
    • The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
    • DOI 10.1038/nature03884
    • Gasser S, Orsulic S, Brown EJ, Raulet DH. The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature. 2005;436(7054):1186-1190. (Pubitemid 41232299)
    • (2005) Nature , vol.436 , Issue.7054 , pp. 1186-1190
    • Gasser, S.1    Orsulic, S.2    Brown, E.J.3    Raulet, D.H.4
  • 48
    • 79952207466 scopus 로고    scopus 로고
    • Novel role for STAT3 in transcriptional regulation of NK immune cell targeting receptor MICA on cancer cells
    • Bedel R, Thiery-Vuillemin A, Grandclement C, et al. Novel role for STAT3 in transcriptional regulation of NK immune cell targeting receptor MICA on cancer cells. Cancer Res. 2011;71(5): 1615-1626.
    • (2011) Cancer Res , vol.71 , Issue.5 , pp. 1615-1626
    • Bedel, R.1    Thiery-Vuillemin, A.2    Grandclement, C.3
  • 49
    • 65449154326 scopus 로고    scopus 로고
    • The cooperative induction of hypoxia-inducible factor-1 alpha and STAT3 during hypoxia induced an impairment of tumor susceptibility to CTL-mediated cell lysis
    • Noman MZ, Buart S, Van Pelt J, et al. The cooperative induction of hypoxia-inducible factor-1 alpha and STAT3 during hypoxia induced an impairment of tumor susceptibility to CTL-mediated cell lysis. J Immunol. 2009;182(6): 3510-3521.
    • (2009) J Immunol , vol.182 , Issue.6 , pp. 3510-3521
    • Noman, M.Z.1    Buart, S.2    Van Pelt, J.3
  • 50
    • 17144387901 scopus 로고    scopus 로고
    • PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-κB, MAPkinase and p53 pathways
    • DOI 10.1038/sj.leu.2403653
    • Grandage VL, Gale RE, Linch DC, Khwaja A. PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways. Leukemia. 2005;19(4): 586-594. (Pubitemid 40521164)
    • (2005) Leukemia , vol.19 , Issue.4 , pp. 586-594
    • Grandage, V.L.1    Gale, R.E.2    Lich, D.C.3    Khwaja, A.4
  • 51
    • 33644974752 scopus 로고    scopus 로고
    • Nfl gene inactivation in acute myeloid leukemia cells confers cytarabine resistance through MAPK and mTOR pathways
    • Yin B, Morgan K, Hasz DE, Mao Z, Largaespada DA. Nfl gene inactivation in acute myeloid leukemia cells confers cytarabine resistance through MAPK and mTOR pathways. Leukemia. 2006;20(1):151-154.
    • (2006) Leukemia , vol.20 , Issue.1 , pp. 151-154
    • Yin, B.1    Morgan, K.2    Hasz, D.E.3    Mao, Z.4    Largaespada, D.A.5
  • 53
    • 84858150371 scopus 로고    scopus 로고
    • Resistance of leukemic stem-like cells in AML cell line KG1a to natural killer cell-mediated cytotoxicity
    • She M, Niu X, Chen X, et al. Resistance of leukemic stem-like cells in AML cell line KG1a to natural killer cell-mediated cytotoxicity. Cancer Lett. 2012;318(2):173-179.
    • (2012) Cancer Lett , vol.318 , Issue.2 , pp. 173-179
    • She, M.1    Niu, X.2    Chen, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.