The glutaredoxin/S-glutathionylation axis regulates interleukin-17A-induced proinflammatory responses in lung epithelial cells in association with S-glutathionylation of nuclear factor κb family proteins

Free Radical Biology and Medicine

Volumn 73, Issue , 2014, Pages 143-153

  Nolin, James D ^a   Tully, Jane E ^a   Hoffman, Sidra M ^a   Guala, Amy S ^a   Van Der Velden, Jos L ^a   Poynter, Matthew E ^a   Van Der Vliet, Albert ^a   Anathy, Vikas ^a   Janssen Heininger, Yvonne M W ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

Free radicals; Glutaredoxin 1; Inhibitory B kinase ; Interleukin 17A; Nuclear factor B; Protein S glutathionylation; Redox

Indexed keywords

I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 17; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; SMALL INTERFERING RNA; SULFENIC ACID DERIVATIVE; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR RELB; CCL20 PROTEIN, MOUSE; CHUK PROTEIN, MOUSE; GLRX PROTEIN, MOUSE; GLUTAREDOXIN; GLUTATHIONE; I KAPPA B KINASE; IL17A PROTEIN, MOUSE; RELA PROTEIN, MOUSE; RELB PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RESPONSE; EPITHELIUM CELL; GENE; GENE EXPRESSION; GENE INDUCTION; GLUTAREDOXIN 1 GENE; LUNG ALVEOLUS EPITHELIUM; MOUSE; NONHUMAN; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN S GLUTATHIONYLATION; TRACHEAL EPITHELIAL CELL; TRANSCRIPTION INITIATION; WILD TYPE; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; LUNG; LUNG DISEASE; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY; PROTEIN PROCESSING; RESPIRATORY TRACT MUCOSA; RNA INTERFERENCE; TRACHEA;

ANIMALS; CELLS, CULTURED; CHEMOKINE CCL20; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; GLUTAREDOXINS; GLUTATHIONE; I-KAPPA B KINASE; INFLAMMATION; INTERLEUKIN-17; INTERLEUKIN-6; LUNG; LUNG DISEASES; MICE; MICE, KNOCKOUT; OXIDATION-REDUCTION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RESPIRATORY MUCOSA; RNA INTERFERENCE; RNA, SMALL INTERFERING; SULFENIC ACIDS; TRACHEA; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR RELB;

EID: 84902164473     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.04.028     Document Type: Article

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