Glutathione supplementation potentiates hypoxic apoptosis by S-glutathionylation of p65-NFκB

Journal of Biological Chemistry

Volumn 282, Issue 25, 2007, Pages 18427-18436

  Qanungo, Suparna ^a   Starke, David W ^a   Pai, Harish V ^a   Mieyal, John J ^a   Nieminen, Anna Liisa ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b 3 134 Wolstein Research Bldg ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; DNA; PHARMACODYNAMICS; PROTEINS; SIGNAL TRANSDUCTION;

HYPOXIC APOPTOSIS; PHARMACOLOGICAL INHIBITION; SIGNALING PATHWAYS; SULFHYDRYL MODIFICATIONS;

FIBROBLASTS;

ACETYLCYSTEINE; ALKYLATING AGENT; DISULFIDE; DITHIOTHREITOL; DNA; GLUTAREDOXIN; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N ETHYLMALEIMIDE; REDUCING AGENT; THIOL DERIVATIVE; TRANSCRIPTION FACTOR RELA;

APOPTOSIS; ARTICLE; BINDING KINETICS; CANCER CHEMOTHERAPY; CATALYSIS; CELL HYPOXIA; CELL LYSATE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA BINDING; HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; REGULATORY MECHANISM; SUPPLEMENTATION;

ANOXIA; ANTINEOPLASTIC AGENTS; APOPTOSIS; CATALYSIS; CELL LINE, TUMOR; CELL NUCLEUS; CYTOPLASM; DNA; GLUTATHIONE; HUMANS; OXIDOREDUCTASES; OXYGEN; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR RELA; TRANSFECTION;

AGOUTI PACA; MURINAE;

EID: 34547128886     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M610934200     Document Type: Article

References (46)

1. Vaupel, P., and Mayer, A. (2005) Transfus. Clin. Biol. 12, 5-10
2. Guo, G., and Bhat, N. R. (2006) Antioxid. Redox. Signal. 8, 911-918
3. Qanungo, S., Wang, M., and Nieminen, A. L. (2004) J. Biol. Chem. 279, 50455-50464
4. Karin, M., and Lin, A. (2002) Nat. Immunol. 3, 221-227
5. Kabe, Y., Ando, K., Hirao, S., Yoshida, M., and Handa, H. (2005) Antioxid. Redox. Signal. 7, 395-403
6. Braun, T., Carvalho, G., Fabre, C., Grosjean, J., Fenaux, P., and Kroemer, G. (2006) Cell Death. Differ. 13, 748-758
7. Wang, C. Y., Guttridge, D. C., Mayo, M. W., and Baldwin, A. S., Jr. (1999) Mol. Cell. Biol. 19, 5923-5929
8. Huxford, T., Malek, S., and Ghosh, G. (1999) Cold Spring Harbor Symp. Quant. Biol. 64, 533-540
9. Ghosh, G., van Duyne, G., Ghosh, S., and Sigler, P. B. (1995) Nature 373, 303-310
10. Berkowitz, B., Huang, D. B., Chen-Park, F. E., Sigler, P. B., and Ghosh, G. (2002) J. Biol. Chem. 277, 24694-24700
11. Klatt, P., and Lamas, S. (2000) Eur. J. Biochem. 267, 4928-4944
12. Brar, S. S., Grigg, C., Wilson, K. S., Holder, W. D., Jr., Dreau, D., Austin, C., Foster, M., Ghio, A. J., Whorton, A. R., Stowell, G. W., Whittall, L. B., Whittle, R. R., White, D. P., and Kennedy, T. P. (2004) Mol. Cancer Ther. 3, 1049-1060
13. Huang, D. B., Phelps, C. B., Fusco, A. J., and Ghosh, G. (2005) J. Mol. Biol. 346, 147-160
14. Mieyal, J. J., Gravina, S. A., Mieyal, P. A., Srinivasan, U., and Starke, D. W. (1995) in Biothiols in Health and Disease (Packer, L., and Cadenas, E., eds) pp. 305-372, Marcel Dekker, Inc., New York
15. Klatt, P., Molina, E. P., De Lacoba, M. G., Padilla, C. A., Martinez-Galesteo, E., Barcena, J. A., and Lamas, S. (1999) FASEB J. 13, 1481-1490
16. Biswas, S., Chida, A. S., and Rahman, I. (2006) Biochem. Pharmacol. 71, 551-564
17. Shelton, M. D., Chock, P. B., and Mieyal, J. J. (2005) Antioxid. Redox. Signal. 7, 348-366
18. Ghezzi, P. (2005) Biochem. Soc. Trans. 33, 1378-1381
19. Gallogly, M. M., and Mieyal, J. J. (2007) Curr. Opin. Pharmacol., in press
20. Starke, D. W., Chock, P. B., and Mieyal, J. J. (2003) J. Biol. Chem. 278, 14607-14613
21. Yang, Y., Jao, S., Nanduri, S., Starke, D. W., Mieyal, J. J., and Qin, J. (1998) Biochemistry 37, 17145-17156
22. Srinivasan, U., Mieyal, P. A., and Mieyal, J. J. (1997) Biochemistry 36, 3199-3206
23. Gravina, S. A., and Mieyal, J. J. (1993) Biochemistry 32, 3368-3376
24. Wang, G. L., Jiang, B. H., and Semenza, G. L. (1995) Biochem. Biophys. Res. Commun. 212, 550-556
25. Chrestensen, C. A., Starke, D. W., and Mieyal, J. J. (2000) J. Biol. Chem. 275, 26556-26565
26. Jiang, B., and Brecher, P. (2000) Hypertension 35, 914-918
27. Qanungo, S., Basu, A., Das, M., and Haldar, S. (2002) Oncogene 21, 4149-4157
28. Shin, H. M., Kim, M. H., Kim, B. H., Jung, S. H., Kim, Y. S., Park, H. J., Hong, J. T., Min, K. R., and Kim, Y. (2004) FEBS Lett. 571, 50-54
29. Nulton-Persson, A. C., Starke, D. W., Mieyal, J. J., and Szweda, L. I. (2003) Biochemistry 42, 4235-4242
30. Cotgreave, I. A., Gerdes, R., Schuppe-Koistinen, I., and Lind, C. (2002) Methods Enzymol. 348, 175-182
31. Humphries, K. M., Juliano, C., and Taylor, S. S. (2002) J. Biol. Chem. 277, 43505-43511
32. Li, Y. Q., Zhang, Z. X., Xu, Y. J., Ni, W., Chen, S. X., Yang, Z., and Ma, D. (2006) Acta Pharmacol. Sin. 27, 339-346
33. Li, X., and Stark, G. R. (2002) Exp. Hematol. 30, 285-296
34. Jones, D. P., Maellaro, E., Jiang, S., Slater, A. F., and Orrenius, S. (1995) Immunol. Lett. 45, 205-209
35. Valko, M., Rhodes, C. J., Moncol, J., Izakovic, M., and Mazur, M. (2006) Chem. Biol. Interact. 160, 1-40
36. Shackelford, R. E., Heinloth, A. N., Heard, S. C., and Paules, R. S. (2005) Antioxid. Redox. Signal. 7, 940-950
37. Moodie, F. M., Marwick, J. A., Anderson, C. S., Szulakowski, P., Biswas, S. K., Bauter, M. R., Kilty, I., and Rahman, I. (2004) FASEB J. 18, 1897-1899
38. Sarkar, A., Sreenivasan, Y., Ramesh, G. T., and Manna, S. K. (2004) J. Biol. Chem. 279, 33768-33781
39. Biaglow, J. E., Ayene, I. S., Tuttle, S. W., Koch, C. J., Donahue, J., and Mieyal, J. J. (2006) Radiat. Res. 165, 307-317
40. Gilbert, H. F. (1995) Methods Enzymol. 251, 8-28
41. Cotgreave, I. A., and Gerdes, R. G. (1998) Biochem. Biophys. Res. Commun. 242, 1-9
42. Thomas, J. A., Chai, Y. C., and Jung, C. H. (1994) Methods Enzymol. 233, 385-395
43. Zhu, S., Manuel, M., Tanaka, S., Choe, N., Kagan, E., and Matalon, S. (1998) Environ. Health Perspect. 106, Suppl. 5, 1157-1163
44. Chiueh, C. C. (1999) Ann. N. Y. Acad. Sci. 890, 301-311
45. Lundberg, M., Johansson, C., Chandra, J., Enoksson, M., Jacobsson, G., Ljung, J., Johansson, M., and Holmgren, A. (2001) J. Biol. Chem. 276, 26269-26275
46. Reynaert, N. L., van der Vliet, A., Guala, A. S., McGovern, T., Hristova, M., Pantano, C., Heintz, N. H., Heim, J., Ho, Y. S., Matthews, D. E., Wouters, E. F., and Janssen-Heininger, Y. M. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 13086-13091