Glutathione-S-transferase P protects against endothelial dysfunction induced by exposure to tobacco smoke

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 296, Issue 5, 2009, Pages

  Conklin, Daniel J ^a   Haberzettl, Petra ^a   Prough, Russell A ^b   Bhatnagar, Aruni ^a,b  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

Acrolein; Aldehydes; Environmental cardiology; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; ACROLEIN; ELECTROPHILE; GLUTATHIONE TRANSFERASE P1;

ANIMAL TISSUE; ARTICLE; CATALYSIS; CIGARETTE SMOKING; CONTROLLED STUDY; DISEASE EXACERBATION; ENDOTHELIAL DYSFUNCTION; LUNG PARENCHYMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; VASCULAR RING;

ACETYLCHOLINE; ACETYLCYSTEINE; ACROLEIN; ANIMALS; ANTIOXIDANTS; AORTA, THORACIC; BLOOD PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; GLUTATHIONE S-TRANSFERASE PI; INHALATION EXPOSURE; LUNG; MALE; MICE; MICE, KNOCKOUT; NITROPRUSSIDE; OXIDATIVE STRESS; SMOKE; TOBACCO; VASODILATION; VASODILATOR AGENTS;

EID: 66149146163     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00867.2008     Document Type: Article

References (48)

1. Awasthi YC, Sharma R, Singhal SS. Human glutathione S-transferases. Int J Biochem 26: 295-308, 1994. (Pubitemid 24118583)
2. Awasthi YC, Yang Y, Tiwari NK, Patrick B, Sharma A, Li J, Awasthi S. Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases. Free Radic Biol Med 37: 607-619, 2004. (Pubitemid 38993509)
3. Aynacioglu AS, Nacak M, Filiz A, Ekinci E, Roots I. Protective role of glutathione S-transferase P1 (GSTP1) Val105Val genotype in patients with bronchial asthma. Br J Clin Pharmacol 57: 213-217, 2004. (Pubitemid 38223534)
4. Barnoya J, Glantz SA. Cardiovascular effects of secondhand smoke: nearly as large as smoking. Circulation 111: 2684-2698, 2005. (Pubitemid 40740869)
5. Barua RS, Ambrose JA, Eales-Reynolds LJ, DeVoe MC, Zervas JG, Saha DC. Dysfunctional endothelial nitric oxide biosynthesis in healthy smokers with impaired endothelium-dependent vasodilatation. Circulation 104: 1905-1910, 2001.
6. Barua RS, Ambrose JA, Srivastava S, DeVoe MC, Eales-Reynolds LJ. Reactive oxygen species are involved in smoking-induced dysfunction of nitric oxide biosynthesis and upregulation of endothelial nitric oxide synthase: an in vitro demonstration in human coronary artery endothelial cells. Circulation 107: 2342-2347, 2003. (Pubitemid 36578506)
7. Beauchamp RO Jr, Andjelkovich DA, Kligerman AD, Morgan KT, Heck HD. A critical review of the literature on acrolein toxicity. Crit Rev Toxicol 14: 309-380, 1985.
8. Berhane K, Widersten M, Engstrom A, Kozarich JW, Mannervik B. Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases. Proc Natl Acad Sci USA 91: 1480-1484, 1994. (Pubitemid 24059036)
9. Bhatnagar A. Cardiovascular pathophysiology of environmental pollutants. Am J Physiol Heart Circ Physiol 286: H479-H485, 2004. (Pubitemid 38140326)
10. Bylock A, Bondjers G, Jansson I, Hansson HA. Surface ultrastructure of human arteries with special reference to the effects of smoking. Acta Pathol Microbiol Scand A 87A: 201-209, 1979. (Pubitemid 9174791)
11. Cao W, Cai L, Rao JY, Pantuck A, Lu ML, Dalbagni G, Reuter V, Scher H, Cordon-Cardo C, Figlin RA, Belldegrun A, Zhang ZF. Tobacco smoking, GSTP1 polymorphism, and bladder carcinoma. Cancer 104: 2400-2408, 2005. (Pubitemid 41691561)
12. Carmella SG, Chen M, Zhang Y, Zhang S, Hatsukami DK, Hecht SS. Quantitation of acrolein-derived (3-hydroxypropyl)mercapturic acid in human urine by liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry: effects of cigarette smoking. Chem Res Toxicol 20: 986-990, 2007. (Pubitemid 47204811)
13. Celermajer DS, Adams MR, Clarkson P, Robinson J, McCredie R, Donald A, Deanfield JE. Passive smoking and impaired endothelium-dependent arterial dilatation in healthy young adults. N Engl J Med 334: 150-154, 1996. (Pubitemid 26017952)
14. Celermajer DS, Sorensen KE, Georgakopoulos D, Bull C, Thomas O, Robinson J, Deanfield JE. Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults. Circulation 88: 2149-2155, 1993. (Pubitemid 23326094)
15. Dong JZ, Moldoveanu SC. Gas chromatography-mass spectrometry of carbonyl compounds in cigarette mainstream smoke after derivatization with 2,4-dinitrophenylhydrazine. J Chromatogr A 1027: 25-35, 2004.
16. Engel LS, Taioli E, Pfeiffer R, Garcia-Closas M, Marcus PM, Lan Q, Boffetta P, Vineis P, Autrup H, Bell DA, Branch RA, Brockmoller J, Daly AK, Heckbert SR, Kalina I, Kang D, Katoh T, Lafuente A, Lin HJ, Romkes M, Taylor JA, Rothman N. Pooled analysis and meta-analysis of glutathione S-transferase M1 and bladder cancer: a HuGE review. Am J Epidemiol 156: 95-109, 2002. (Pubitemid 34759966)
17. Ezzati M, Lopez AD. Estimates of global mortality attributable to smoking in 2000. Lancet 362: 847-852, 2003. (Pubitemid 37130092)
18. Ghilarducci DP, Tjeerdema RS. Fate and effects of acrolein. Rev Environ Contam Toxicol 144: 95-146, 1995.
19. Green N, Weech M, Walters E. Localization and characterization of glutathione-s-transferase isozymes alpha, mu, and pi within the mouse vomeronasal organ. Neurosci Lett 375: 198-202, 2005. (Pubitemid 40202952)
20. Guo X, Oldham MJ, Kleinman MT, Phalen RF, Kassab GS. Effect of cigarette smoking on nitric oxide, structural, and mechanical properties of mouse arteries. Am J Physiol Heart Circ Physiol 291: H2354-H2361, 2006.
21. Habig WH, Pabst MJ, Jakoby Glutathione Stransferases WB. The first enzymatic step in mercapturic acid formation. J Biol Chem 249: 7130-7139, 1974.
22. Harries LW, Stubbins MJ, Forman D, Howard GC, Wolf CR. Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer. Carcinogenesis 18: 641-644, 1997. (Pubitemid 28132446)
23. Hayes JD, Pulford DJ. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol 30: 445-600, 1995.
24. Henderson CJ, Smith AG, Ure J, Brown K, Bacon EJ, Wolf CR. Increased skin tumorigenesis in mice lacking pi class glutathione S-transferases. Proc Natl Acad Sci USA 95: 5275-5280, 1998. (Pubitemid 28208588)
25. Howard G, Wagenknecht LE, Burke GL, ez-Roux A, Evans GW, McGovern P, Nieto FJ, Tell GS. Cigarette smoking and progression of atherosclerosis: the Atherosclerosis Risk in Communities (ARIC) Study. JAMA 279: 119-124, 1998.
26. Hu X, Herzog C, Zimniak P, Singh SV. Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase. Cancer Res 59: 2358-2362, 1999. (Pubitemid 29242283)
27. Hu X, Ji X, Srivastava SK, Xia H, Awasthi S, Nanduri B, Awasthi YC, Zimniak P, Singh SV. Mechanism of differential catalytic efficiency of two polymorphic forms of human glutathione S-transferase P1-1 in the glutathione conjugation of carcinogenic diol epoxide of chrysene. Arch Biochem Biophys 345: 32-38, 1997. (Pubitemid 27374205)
28. Huang J, Tan PH, Tan BK, Bay BH. GST-pi expression correlates with oxidative stress and apoptosis in breast cancer. Oncol Rep 12: 921-925, 2004.
29. Hutchison SJ, Glantz SA, Zhu BQ, Sun YP, Chou TM, Chatterjee K, Deedwania PC, Parmley WW, Sudhir K. In-utero and neonatal exposure to secondhand smoke causes vascular dysfunction in newborn rats. J Am Coll Cardiol 32: 1463-1467, 1998. (Pubitemid 28522411)
30. Hutchison SJ, Sievers RE, Zhu BQ, Sun YP, Stewart DJ, Parmley WW, Chatterjee K. Secondhand tobacco smoke impairs rabbit pulmonary artery endothelium-dependent relaxation. Chest 120: 2004-2012, 2001.
31. Lee YL, Lin YC, Lee YC, Wang JY, Hsiue TR, Guo YL. Glutathione S-transferase P1 gene polymorphism and air pollution as interactive risk factors for childhood asthma. Clin Exp Allergy 34: 1707-1713, 2004.
32. Mapp CE, Fryer AA, De MN, Pozzato V, Padoan M, Boschetto P, Strange RC, Hemmingsen A, Spiteri MA. Glutathione S-transferase GSTP1 is a susceptibility gene for occupational asthma induced by isocyanates. J Allergy Clin Immunol 109: 867-872, 2002. (Pubitemid 34499523)
33. Masetti S, Botto N, Manfredi S, Colombo MG, Rizza A, Vassalle C, Clerico A, Biagini A, Andreassi MG. Interactive effect of the glutathione S-transferase genes and cigarette smoking on occurrence and severity of coronary artery risk. J Mol Med 81: 488-494, 2003. (Pubitemid 37070201)
34. McIlwain CC, Townsend DM, Tew KD. Glutathione S-transferase polymorphisms: cancer incidence and therapy. Oncogene 25: 1639-1648, 2006.
35. Pal A, Hu X, Zimniak P, Singh SV. Catalytic efficiencies of allelic variants of human glutathione S-transferase Pi in the glutathione conjugation of alpha, beta-unsaturated aldehydes. Cancer Lett 154: 39-43, 2000. (Pubitemid 30229907)
36. Raij L, DeMaster EG, Jaimes EA. Cigarette smoke-induced endothelium dysfunction: role of superoxide anion. J Hypertens 19: 891-897, 2001. (Pubitemid 32436953)
37. Rangasamy T, Cho CY, Thimmulappa RK, Zhen L, Srisuma SS, Kensler TW, Yamamoto M, Petrache I, Tuder RM, Biswal S. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest 114: 1248-1259, 2004. (Pubitemid 40385296)
38. Reszka E, Wasowicz W. Significance of genetic polymorphisms in glutathione S-transferase multigene family and lung cancer risk. Int J Occup Med Environ Health 14: 99-113, 2001. (Pubitemid 32642853)
39. Smith CJ, Fischer TH. Particulate and vapor phase constituents of cigarette mainstream smoke and risk of myocardial infarction. Atherosclerosis 158: 257-267, 2001.
40. Spiteri MA, Bianco A, Strange RC, Fryer AA. Polymorphisms at the glutathione S-transferase, GSTP1 locus: a novel mechanism for susceptibility and development of atopic airway inflammation. Allergy 55, Suppl 61: 15-20, 2000. (Pubitemid 30430373)
41. Srivastava S, Harter TM, Chandra A, Bhatnagar A, Srivastava SK, Petrash JM. Kinetic studies of FR-1, a growth factor-inducible aldo-keto reductase. Biochemistry 37: 12909-12917, 1998. (Pubitemid 28433524)
42. Steinkellner H, Hoelzl C, Uhl M, Cavin C, Haidinger G, Gsur A, Schmid R, Kundi M, Bichler J, Knasmuller S. Coffee consumption induces GSTP in plasma and protects lymphocytes against (+/-)-antibenzo[a]pyrene-7,8-dihydrodiol-9,10- epoxide induced DNA-damage: results of controlled human intervention trials. Mutat Res 591: 264-275, 2005. (Pubitemid 41654854)
43. Stevens JF, Maier CS. Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease. Mol Nutr Food Res 52: 7-25, 2008.
44. 't Hoen PA, Rooseboom M, Bijsterbosch MK, van Berkel TJ, Vermeulen NP, Commandeur JN. Induction of glutathione-S-transferase mRNA levels by chemopreventive selenocysteine Se-conjugates. Biochem Pharmacol 63: 1843-1849, 2002.
45. Tsai CW, Yang JJ, Chen HW, Sheen LY, Lii CK. Garlic organosulfur compounds upregulate the expression of the pi class of glutathione S-transferase in rat primary hepatocytes. J Nutr 135: 2560-2565, 2005.
46. Watson MA, Stewart RK, Smith GB, Massey TE, Bell DA. Human glutathione S-transferase P1 polymorphisms: relationship to lung tissue enzyme activity and population frequency distribution. Carcinogenesis 19: 275-280, 1998.
47. Wilson MH, Grant PJ, Hardie LJ, Wild CP. Glutathione S-transferase M1 null genotype is associated with a decreased risk of myocardial infarction. FASEB J 14: 791-796, 2000.
48. Zimniak P, Singh SP. Families of glutathione transferases. In: Toxicology of Glutathione Transferases, edited by Awasthi YC. Boca Raton, FL: CRC, 2006, p. 11-26.