Stromal interaction molecule 1 (STIM1) is involved in the regulation of mitochondrial shape and bioenergetics and plays a role in oxidative stress

Journal of Biological Chemistry

Volumn 287, Issue 50, 2012, Pages 42042-42052

  Henke, Nadine ^a   Albrecht, Philipp ^a   Pfeiffer, Annika ^a   Toutzaris, Diamandis ^a   Zanger, Klaus ^a   Methner, Axel ^a,b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITIONAL STRESS; APOPTOSIS-INDUCING FACTORS; CALCIUM IONS; CELLULAR FUNCTION; ENDOPLASMIC RETICULUM; GLUTATHIONES; INITIATION FACTORS; INTRACELLULAR CA; KNOCK OUTS; MITOCHONDRIAL ENERGY; MOUSE EMBRYONIC FIBROBLASTS; NUCLEAR TRANSLOCATIONS; OVER-EXPRESSION; WILD TYPES;

CALCIUM; CELL CULTURE; CELL DEATH; CELL MEMBRANES; MITOCHONDRIA; PHOSPHORYLATION; TRANSCRIPTION; TRANSCRIPTION FACTORS;

OXIDATIVE STRESS;

CALCIUM ION; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; ENDOPLASMIC RETICULUM KINASE PERK; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE S TRANSFERASE OMEGA 1; HEME OXYGENASE 1; INITIATION FACTOR 2ALPHA; PEROXIREDOXIN 1; PROTEIN KINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); STROMAL INTERACTION MOLECULE 1; SUPEROXIDE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOENERGY; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1 DEFICIENCY; CELL DEATH; CELL TRANSPORT; CELLULAR PARAMETERS; CONTROLLED STUDY; EMBRYO; GCL GENE; GENE OVEREXPRESSION; GPX1 GENE; GSTO1 GENE; HO 1 GENE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL SHAPE; MITOCHONDRION; MOUSE; NONHUMAN; NQO1 GENE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PRX1 GENE; STROMAL INTERACTION MOLECULE 1 DEFICIENCY; UPREGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; APOPTOSIS; CALCIUM; CALCIUM CHANNELS; CELLS, CULTURED; EIF-2 KINASE; EMBRYO, MAMMALIAN; ENERGY METABOLISM; EUKARYOTIC INITIATION FACTOR-2; FIBROBLASTS; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; OXIDATIVE STRESS; PHOSPHORYLATION;

EID: 84871311580     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.417212     Document Type: Article

References (38)

1. Takemura, H., and Putney, J. W. (1989) Capacitative calcium entry in parotid acinar cells. Biochem. J. 258, 409-412 (Pubitemid 19075512)
2. Takemura, H., Hughes, A. R., Thastrup, O., and Putney, J. W. (1989) Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. Evidence that an intracellular calcium pool and not an inositol phosphate regulates calcium fluxes at the plasma membrane. J. Biol. Chem. 264, 12266-12271 (Pubitemid 19191112)
3. 2+ store refilling. J. Biol. Chem. 278, 44769-44779
4. Frieden, M., Arnaudeau, S., Castelbou, C., and Demaurex, N. (2005) Subplasmalemmal mitochondria modulate the activity of plasma membrane Ca2+-ATPases. J. Biol. Chem. 280, 43198-43208 (Pubitemid 43049286)
5. 2+ ATPases (SERCA) pumps silently refill the endoplasmic reticulum. J. Biol. Chem. 282, 11456-11464
6. Jouaville, L. S., Pinton, P., Bastianutto, C., Rutter, G. A., and Rizzuto, R. (1999) Regulation of mitochondrial ATP synthesis by calcium. Evidence for a long-term metabolic priming. Proc. Natl. Acad. Sci. U.S.A. 96, 13807-13812
7. Roos, J., DiGregorio, P. J., Yeromin, A. V., Ohlsen, K., Lioudyno, M., Zhang, S., Safrina, O., Kozak, J. A., Wagner, S. L., Cahalan, M. D., Veliçelebi, G., and Stauderman, K. A. (2005) STIM1, an essential and conserved component of store-operated Ca2+ channel function. J. Cell Biol. 169, 435-445 (Pubitemid 40686694)
8. 2+ influx. Curr. Biol. 15, 1235-1241
9. 2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane. J. Cell Biol. 174, 803-813
10. 2+ channel activity. Proc. Natl. Acad. Sci. U.S.A. 103, 9357-9362
11. Prakriya, M., Feske, S., Gwack, Y., Srikanth, S., Rao, A., and Hogan, P. G. (2006) Orai1 is an essential pore subunit of the CRAC channel. Nature 443, 230-233 (Pubitemid 44387613)
12. Mignen, O., Thompson, J. L., and Shuttleworth, T. J. (2008) Orai1 subunit stoichiometry of the mammalian CRAC channel pore. J. Physiol. 586, 419-425
13. 2+ store to the plasma membrane. Nature 437, 902-905
14. Mercer, J. C., Dehaven, W. I., Smyth, J. T., Wedel, B., Boyles, R. R., Bird, G. S., and Putney, J. W. (2006) Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1. J. Biol. Chem. 281, 24979-24990 (Pubitemid 44274268)
15. Soboloff, J., Spassova, M. A., Tang, X. D., Hewavitharana, T., Xu, W., and Gill, D. L. (2006) Orai1 and STIM reconstitute store-operated calcium channel function. J. Biol. Chem. 281, 20661-20665 (Pubitemid 44115407)
16. 2+ ATPase (SERCA) is the third element in capacitative calcium entry. Cell Calcium 47, 412-418
17. Zhivotovsky, B., and Orrenius, S. (2011) Calcium and cell death mechanisms. A perspective from the cell death community. Cell Calcium 50, 211-221
18. Sabbioni, S., Barbanti-Brodano, G., Croce, C. M., and Negrini, M. (1997) GOK. A gene at 11p15 involved in rhabdomyosarcoma and rhabdoid tumor development. Cancer Res. 57, 4493-4497 (Pubitemid 27441051)
19. 2+ channels that lead to normal epithelial cell apoptosis. Mol. Biol. Cell 19, 2220-2230
20. 2+-signaling sustains constitutive activation of protein kinase B/Akt and augments survival of malignant melanoma cells. Cell Calcium 47, 525-537
21. Liu, H., Hughes, J. D., Rollins, S., Chen, B., and Perkins, E. (2011) Calcium entry via ORAI1 regulates glioblastoma cell proliferation and apoptosis. Exp. Mol. Pathol. 91, 753-760
22. Hawkins, B. J., Irrinki, K. M., Mallilankaraman, K., Lien, Y.-C., Wang, Y., Bhanumathy, C. D., Subbiah, R., Ritchie, M. F., Soboloff, J., Baba, Y., Kurosaki, T., Joseph, S. K., Gill, D. L., and Madesh, M. (2010) S-Glutathionylation activates STIM1 and alters mitochondrial homeostasis. J. Cell Biol. 190, 391-405
23. - as a neuroprotective drug target. CNS Neurol. Disord. Drug Targets 9, 373-382
24. Itoh, K., Wakabayashi, N., Katoh, Y., Ishii, T., Igarashi, K., Engel, J. D., and Yamamoto, M. (1999) Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 13, 76-86 (Pubitemid 29045117)
25. Yamamoto, T., Suzuki, T., Kobayashi, A., Wakabayashi, J., Maher, J., Motohashi, H., and Yamamoto, M. (2008) Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity. Mol. Cell. Biol. 28, 2758-2770 (Pubitemid 351542373)
26. Cullinan, S. B., Zhang, D., Hannink, M., Arvisais, E., Kaufman, R. J., and Diehl, J. A. (2003) Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol. Cell. Biol. 23, 7198-7209 (Pubitemid 37211002)
27. Lewerenz, J., and Maher, P. (2009) Basal levels of eIF2α phosphorylation determine cellular antioxidant status by regulating ATF4 and xCT expression. J. Biol. Chem. 284, 1106-1115
28. 2+ to the endoplasmic reticulum and prevent the depletion of neighboring endoplasmic reticulum regions. J. Biol. Chem. 276, 29430-29439
29. Westermann, B. (2010) Mitochondrial fusion and fission in cell life and death. Nat. Rev. Mol. Cell Biol. 11, 872-884
30. Grohm, J., Plesnila, N., and Culmsee, C. (2010) Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death. Brain Behav Immun. 24, 831-838
31. Landshamer, S., Hoehn, M., Barth, N., Duvezin-Caubet, S., Schwake, G., Tobaben, S., Kazhdan, I., Becattini, B., Zahler, S., Vollmar, A., Pellecchia, M., Reichert, A., Plesnila, N., Wagner, E., and Culmsee, C. (2008) Bid-induced release of AIF from mitochondria causes immediate neuronal cell death. Cell Death Differ. 15, 1553-1563
32. Cao, G., Xing, J., Xiao, X., Liou, A. K., Gao, Y., Yin, X.-M., Clark, R. S., Graham, S. H., and Chen, J. (2007) Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury. J. Neurosci. 27, 9278-9293 (Pubitemid 47358221)
33. Brandman, O., Liou, J., Park, W. S., and Meyer, T. (2007) STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels. Cell 131, 1327-1339 (Pubitemid 350297421)
34. Sampieri, A., Zepeda, A., Asanov, A., and Vaca, L. (2009) Visualizing the store-operated channel complex assembly in real time. Identification of SERCA2 as a new member. Cell Calcium 45, 439-446
35. 2+ depletion in cardiac myocytes. Free Radic. Biol. Med. 48, 1182-1187
36. 2+-dependent redox modulation of SERCA 2b by ERp57. J. Cell Biol. 164, 35-46
37. 2+ entry by the endoplasmic reticulum luminal oxidoreductase ERp57. EMBO Rep. 12, 1182-1188
38. Zhang, D. D., Lo, S.-C., Cross, J. V., Templeton, D. J., and Hannink, M. (2004) Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Mol. Cell. Biol. 24, 10941-10953 (Pubitemid 39603148)