Adaptive, model-based control by the Open-Loop-Feedback-Optimal (OLFO) controller for the effective fed-batch cultivation of hybridoma cells

Biotechnology Progress

Volumn 18, Issue 5, 2002, Pages 1095-1103

  Frahm, Björn ^a   Lane, Paul ^b   Atzert, Hendrik ^a   Munack, Axel ^a   Hoffmann, Martin ^a   Hass, Volker C ^a   Pörtner, Ralf ^a  

^a HAMBURG UNIVERSITY OF TECHNOLOGY   (Germany)

^b INSTITUTE FOR EPIDEMIOLOGY AND PATHOGEN DIAGNOSTICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MODEL-BASED CONTROL;

CULTIVATION; DRUG PRODUCTS; METABOLISM; OPTIMIZATION; PROCESS CONTROL;

CELL CULTURE;

ALGORITHMS; ANIMALS; BIOREACTORS; CELL LINE; CELL SURVIVAL; COMPUTER SIMULATION; CULTURE MEDIA; EQUIPMENT DESIGN; FEASIBILITY STUDIES; FEEDBACK; GLUCOSE; GLUTAMINE; HYBRIDOMAS; LINEAR MODELS; MICE; MODELS, BIOLOGICAL; QUALITY CONTROL; SENSITIVITY AND SPECIFICITY;

ANIMALIA;

EID: 0036752465     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp020035y     Document Type: Article

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