Systematic development of predictive mathematical models for animal cell cultures

Computers and Chemical Engineering

Volumn 34, Issue 8, 2010, Pages 1192-1198

  Kontoravdi, Cleo ^a   Pistikopoulos, Efstratios N ^a   Mantalaris, Athanasios ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Global sensitivity analysis; Mammalian cell culture; Mathematical modelling

Indexed keywords

ANTIBODY-SECRETING HYBRIDOMAS; BATCH CULTURE; COMPUTATIONAL DEMANDS; FED BATCHES; FED-BATCH CULTURES; GLOBAL SENSITIVITY ANALYSIS; INDEPENDENT SET; INITIAL VALUES; MAMMALIAN CELL CULTURE; MATHEMATICAL MODELLING; MODEL DEVELOPMENT; MODEL PARAMETERS; MODEL RELIABILITY; MODEL-BASED CONTROL; MODEL-BASED TOOLS; OPTIMAL EXPERIMENTAL DESIGNS; OPTIMISATIONS; PREDICTIVE CAPABILITIES; PREDICTIVE MODELS; SYSTEMATIC FRAMEWORK;

ANIMAL CELL CULTURE; BATCH CELL CULTURE; CELL CULTURE; MAMMALS; MODEL CHECKING; MODEL PREDICTIVE CONTROL; MONOCLONAL ANTIBODIES; OPTIMIZATION; PARAMETER ESTIMATION; PRODUCTIVITY; SENSITIVITY ANALYSIS;

MATHEMATICAL MODELS;

EID: 77955549294     PISSN: 00981354     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.compchemeng.2010.03.012     Document Type: Article

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