Cellular functions of the dual-targeted catalytic subunit of telomerase, telomerase reverse transcriptase - Potential role in senescence and aging

Experimental Gerontology

Volumn 56, Issue , 2014, Pages 189-193

  Ale Agha, Niloofar ^b   Dyballa Rukes, Nadine ^b   Jakob, Sascha ^b   Altschmied, Joachim ^b   Haendeler, Judith ^a,b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b IUF LEIBNIZ RESEARCH INSTITUTE FOR ENVIRONMENTAL MEDICINE   (Germany)

Author keywords

Aging; Mitochondria; Nucleus; Senescence; Telomerase reverse transcriptase

Indexed keywords

MITOCHONDRIAL DNA; PROTEIN KINASE B; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; TERT PROTEIN, HUMAN;

AGING; APOPTOSIS; CELL FUNCTION; CELL NUCLEUS; CELL PROLIFERATION; CELL TYPE; DNA DAMAGE; ENZYME ACTIVITY; HUMAN; LIFESPAN; MITOCHONDRION; MITOSIS; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN TARGETING; PROTEIN TRANSPORT; REVIEW; SENESCENCE; ACTIVE TRANSPORT; AGE; ANIMAL; CELL AGING; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TELOMERE;

ACTIVE TRANSPORT, CELL NUCLEUS; AGE FACTORS; AGING; ANIMALS; CATALYTIC DOMAIN; CELL AGING; HUMANS; MITOCHONDRIA; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TELOMERASE; TELOMERE;

EID: 84901837487     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2014.02.011     Document Type: Review

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