Antidepressant activity of astilbin: Involvement of monoaminergic neurotransmitters and BDNF signal pathway

Biological and Pharmaceutical Bulletin

Volumn 37, Issue 6, 2014, Pages 987-995

  Lv, Qiong Qiong ^a   Wu, Wen Jie ^b   Guo, Xiao Liang ^b   Liu, Rui Li ^a   Yang, Yu Ping ^a   Zhou, Du Shuang ^a   Zhang, Ji Xia ^a   Liu, Ju Yuan ^a  

^a School of Pharmacy   (China)

^b XINXIANG MEDICAL UNIVERSITY   (China)

Author keywords

Astilbin; Brain derived neurotrophic factor; Chronic unpredictable mild stress; Depression; Dopamine; Serotonin

Indexed keywords

ASTILBIN; BRAIN DERIVED NEUROTROPHIC FACTOR; DOPAMINE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE B; SEROTONIN; ANTIDEPRESSANT AGENT; BIOGENIC AMINE; FLAVONOL DERIVATIVE;

ADULT; ANHEDONIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG EFFICACY; DRUG SAFETY; ENZYME ACTIVITY; FORCED SWIM TEST; FRONTAL CORTEX; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LINEAR REGRESSION ANALYSIS; LOCOMOTION; MALE; MONOAMINERGIC SYSTEM; MOUSE; NEUROTRANSMISSION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STRESS; SUCROSE PREFERENCE TEST; TAIL SUSPENSION TEST; UPREGULATION; WESTERN BLOTTING; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; CHRONIC DISEASE; DISEASE MODEL; DRUG EFFECTS; DRUG THERAPY; FOOD PREFERENCE; MENTAL STRESS; METABOLISM; MOTOR ACTIVITY; PSYCHOLOGY; SWIMMING;

ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; BIOGENIC MONOAMINES; BRAIN-DERIVED NEUROTROPHIC FACTOR; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; DOPAMINE; FLAVONOLS; FOOD PREFERENCES; MALE; MICE, INBRED C57BL; MOTOR ACTIVITY; SEROTONIN; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL; SWIMMING;

EID: 84901835759     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b13-00968     Document Type: Article

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