The risk of hydroquinone and sunscreen over-absorption via photodamaged skin is not greater in senescent skin as compared to young skin: Nude mouse as an animal model

International Journal of Pharmaceutics

Volumn 471, Issue 1-2, 2014, Pages 135-145

  Hung, Chi Feng ^a   Chen, Wei Yu ^b,c   Aljuffali, Ibrahim A ^d   Shih, Hui Chi ^e   Fang, Jia You ^e,f  

^a FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d KING SAUD UNIVERSITY   (Saudi Arabia)

^e CHANG GUNG UNIVERSITY   (Taiwan)

^f CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Hydroquinone; Intrinsic aging; Percutaneous absorption; Photoaging; Sunscreen; Tight junction

Indexed keywords

AVOBENZONE; CYCLOOXYGENASE 2; CYTOKERATIN; DNA NUCLEOTIDYLEXOTRANSFERASE; HEAT SHOCK PROTEIN; HYDROQUINONE; OXYBENZONE; RHODAMINE 123; SUNSCREEN; UVOMORULIN; ZINC OXIDE; CADHERIN; HYDROQUINONE DERIVATIVE; KERATIN; PTGS2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CUTANEOUS PARAMETERS; DEGRADATION; DERMOEPIDERMAL JUNCTION; HYDROPHILICITY; HYPERPLASIA; IMMUNOBLOTTING; IMMUNOHISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LIPOPHILICITY; MOUSE; NICK END LABELING; NONHUMAN; PHOTOAGING; PRIORITY JOURNAL; RADIATION EXPOSURE; SKIN ABSORPTION; SKIN DEFECT; SKIN PERMEABILITY; SKIN PHOTODAMAGE; SKIN WATER LOSS; TIGHT JUNCTION; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION; UPREGULATION; ANIMAL; DRUG EFFECTS; FEMALE; FLUORESCENCE MICROSCOPY; HAIR FOLLICLE; METABOLISM; NUDE MOUSE; RADIATION RESPONSE; SKIN; ULTRAVIOLET RADIATION;

ANIMALS; CADHERINS; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HAIR FOLLICLE; HEAT-SHOCK PROTEINS; HYDROQUINONES; KERATINS; MICE, NUDE; MICROSCOPY, FLUORESCENCE; SKIN; SKIN ABSORPTION; SKIN AGING; SUNSCREENING AGENTS; ULTRAVIOLET RAYS;

EID: 84901822813     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.05.034     Document Type: Article

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