Linoleate appears to protect against palmitate-induced inflammation in Huh7 cells

Lipids in Health and Disease

Volumn 13, Issue 1, 2014, Pages

  Maruyama, Hitoshi ^a   Takahashi, Masanori ^a   Sekimoto, Tadashi ^a   Shimada, Taro ^a   Yokosuka, Osamu ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

Hepatocyte; Interleukin 8; Linoleate; Nonalcoholic steatohepatitis; Palmitate; Proinflammatory cytokine

Indexed keywords

CASPASE 3; INTERLEUKIN 8; LINOLEIC ACID; MESSENGER RNA; OMEGA 6 FATTY ACID; PALMITIC ACID; STRESS ACTIVATED PROTEIN KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PALMITIC ACID DERIVATIVE;

ARTICLE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; HEPG2 CELL LINE; HUMAN; HUMAN CELL; INFLAMMATION; LIPID STORAGE; LIVER CELL; OUTCOME ASSESSMENT; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; QUANTITATIVE STUDY; TREATMENT DURATION; CELL LINE; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; TOXICITY;

CELL LINE; HEP G2 CELLS; HEPATOCYTES; HUMANS; INFLAMMATION; INTERLEUKIN-8; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LINOLEIC ACID; NF-KAPPA B; PALMITATES;

EID: 84901761961     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-13-78     Document Type: Article

References (38)

1. Non-alcoholic steatohepatitis (NASH): a disease of emerging identify and importance. James OFW, Day CP, J Hepatol 1998 29 495 501 10.1016/S0168-8278(98) 80073-1 9765002
2. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Browning JD, Szczepaniak LS, Dobbins R, Nuremberg P, Horton JD, Cohen JC, Grundy SM, Hobbs HH, Hepatology 2004 40 1387 1395 10.1002/hep.20466 15565570
3. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormailties. Sanyal AJ, Campbell-Sargent C, Mirshahi F, Rizzo WB, Contos MJ, Sterling RK, Luketic VA, Shiffman ML, Clore JN, Gastroenterology 2001 120 1183 1192 10.1053/gast.2001.23256 11266382
4. Non-alcoholic steatohepatitis: from cell biology to clinical practice. Cortez-Pinto H, de Moura MC, Day CP, J Hepatol 2006 44 197 208 10.1016/j.jhep.2005.09.002 16274837
5. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the american gastroenterological association, American Association for the study of liver diseases, and American College of Gastroenterology. Chalasani N, Younossi Z, Lavine JE, Diehl AM, Brunt EM, Cusi K, Charlton M, Sanyal AJ, American Gastroenterological Association; American Association for the Study of Liver Diseases, Gastroenterology 2012 142 1592 1609 10.1053/j.gastro.2012.04.001 22656328
6. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Farrell GC, Larter CZ, Hepatology 2006 43 Suppl 99 S112 16447287
7. Nonalcoholic steatohepatitis: summary of an AASLD single topic conference. Neuschwander-Tetri BA, Caldwell SH, Hepatology 2003 37 1202 1219 10.1053/jhep.2003.50193 12717402
8. Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alfa expression via a lysosomal pathway. Feldstein AE, Werneburg NW, Canbay A, Guicciardi ME, Bronk SF, Rydzewski R, Burgart LJ, Gores GJ, Hepatology 2004 40 185 194 10.1002/hep.20283 15239102
9. Nutritional assessment and hepatic fatty acid composition in non-alcoholic fatty liver disease (NAFLD): a cross-sectional study. Allard JP, Aghdassi E, Mohammed S, Raman M, Avand G, Arendt BM, Jalali P, Kandasamy T, Prayitno N, Sherman M, Guindi M, Ma DW, Heathcote JE, J Hepatol 2008 48 300 307 10.1016/j.jhep.2007.09.009 18086506
10. The plasma lipidomic signature of nonalcoholic steatohepatitis. Puri P, Wiest MM, Cheung O, Mirshahi F, Sargeant C, Min HK, Contos MJ, Sterling RK, Fuchs M, Zhou H, Watkins SM, Sanyal AJ, Hepatology 2009 50 1827 1838 10.1002/hep.23229 19937697
11. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ, J Clin Invest 2005 115 1343 1351 10.1172/JCI23621 15864352
12. Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis. Malhi H, Bronk SF, Werneburg NW, Gores GJ, J Biol Chem 2006 281 12093 12101 10.1074/jbc.M510660200 16505490
13. Saturated fat intake and insulin resistance in men with coronary artery disease. the stanford coronary risk intervention project investigators and staff. Maron DJ, Fair JM, Haskell WL, Circulation 1991 84 2020 2027 10.1161/01.CIR.84.5.2020 1934376
14. Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: the role of toll-like receptors 2 and 4. Szabo G, Velayudham A, Romics L Jr, Mandrekar P, Alcohol Clin Exp Res 2005 29 11 Suppl 140S 145S 16344599
15. Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells. Csak T, Ganz M, Pespisa J, Kodys K, Dolganiuc A, Szabo G, Hepatology 2011 54 133 144 10.1002/hep.24341 21488066
16. Palmitic acid induces production of proinflammatory cytokine interleukin-8 from hepatocytes. Joshi-Barve S, Barve SS, Amancheria K, Gobejishvili L, Hill D, Cave M, Hote P, McClain CJ, Hepatology 2007 46 823 830 10.1002/hep.21752 17680645
17. Cytokine-induced gene extpression of a neutrophil chemotactic factor/IL-8 in human hepatocytes. Thornton AJ, Strieter RM, Lindley I, Baggiolini M, Kunkel SL, J Immunol 1990 144 2609 2613 2156928
18. Expression of cytokine signaling genes in morbidly obese patients with non-alcoholic steatohepatitis and hepatic fibrosis. Estep JM, Baranova A, Hossain N, Elariny H, Ankrah K, Afendy A, Chandhoke V, Younossi ZM, Obes Surg 2009 19 617 624 10.1007/s11695-009-9814-x 19280268
19. Palmitate activates the NF-κB Transcription Factor and Induces IL-6 and TNF expression in 3 T3-L1 adipocytes. Ajuwon KM, Spurlock ME, J Nutr 2005 135 1841 1846 16046706
20. Poluunsaturated fatty acid regulation of gene transcription: a molecular mechanism to improve the metabolic syndrome. Clarke SD, J Nutr 2001 131 1129 1132 11285313
21. Trial Investigators: n-3 Fatty Acids and Cardiovascular Outcomes in Patients with Dysglycemia. The ORIGIN, N Engl J Med 2012 367 309 318 22686415
22. Clinical aspects of essential fatty acid metabolism: Jonathan Rhoads Lecture. Bistrian BR, J Parenter Enteral Nutr 2003 27 168 175 10.1177/0148607103027003168
23. Commentary on a trial comparing krill oil versus fish oil. Nichols PD, Kitessa SM, Abeywardena M, Lipids Health Dis 2014 13 2 10.1186/1476-511X-13-2 24383554
24. Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells. Wei Y, Wang D, Gentile CL, Pagliassotti MJ, Mol Cell Biochem 2009 331 31 40 10.1007/s11010-009-0142-1 19444596
25. Differential effect of oleic and palmitic acid on lipid accumulation and apoptosis in cultured hepatocytes. Ricchi M, Odoardi MR, Carulli L, Anzivino C, Ballestri S, Pinetti A, Fantoni LI, Marra F, Bertolotti M, Banni S, Lonardo A, Carulli N, Loria P, J Gastroenterol Hepatol 2009 24 830 840 10.1111/j.1440-1746. 2008.05733.x 19207680
26. Palmitate induces insulin resistance without significant intracellular triglyceride accumulation in HepG2 cells. Lee JY, Cho HK, Kwon YH, Metabolism 2010 59 927 934 10.1016/j.metabol.2009.10.012 20006364
27. Steatohepatitis: a tale of two "hits"? Day CP, James OF, Gastroenterology 1998 114 842 845 10.1016/S0016-5085(98)70599-2 9547102
28. Unsaturated fatty acids prevent activation of NLRP3 inflammasome in human monocytes/macrophages. L'homme L, Esser N, Riva L, Scheen A, Paquot N, Piette J, Legrand-Poels S, J Lipid Res 2013 54 2998 3008 10.1194/jlr.M037861 24006511
29. The fatty acid composition of skeletal muscle membrane phospholipid: its relationship with the type of feeding and plasma glucose levels in young children. Baur LA, O'Connor J, Pan DA, Kriketos AD, Storlien LH, Metabolism 1998 47 106 112 10.1016/S0026-0495(98)90202-5 9440487
30. Potency of polyunsaturated and saturated fats as short-term inhibitors of hepatic lipogenesis in rats. Wilson MD, Blake WL, Salati LM, Clarke SD, J Nutr 1990 120 544 552 2352029
31. Sterol regulatory element binding protein-1 expression is suppressed by dietary polyunsaturated fatty acids. Xu J, Nakamura MT, Cho HP, Clarke SD, J Biol Chem 1999 274 23577 23583 10.1074/jbc.274.33.23577 10438539
32. Omega 3-Omega 6: what is right for the liver? El-Badry AM, Graf R, Clavien PA, J Hepatol 2007 47 718 725 10.1016/j.jhep.2007.08.005 17869370
33. Palmitic and linoleic acids induce ER stress and apoptosis in hepatoma cells. Zhang Y, Xue R, Zhang Z, Yang X, Shi H, Lipids Health Dis 2012 11 1 10.1186/1476-511X-11-1 22221411
34. ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). Reiner Z, Catapano AL, De Backer G, Graham I, Taskinen MR, Wiklund O, Agewall S, Alegria E, Chapman MJ, Durrington P, Erdine S, Halcox J, Hobbs R, Kjekshus J, Filardi PP, Riccardi G, Storey RF, Wood D, Eur Heart J 2011 32 1769 1818 21712404
35. Dietary fish as a major component of a weight-loss diet: effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects. Mori TA, Bao DQ, Burke V, Pudey IB, Watts GF, Beilin LJ, Am J Clin Nutr 1999 70 817 825 10539741
36. Dietary intake of alpha-linolenic acid and risk of fatal ischemic heart disease among women. Hu FB, Stampfer MJ, Manson JE, Rimm EB, Wolk A, Colditz GA, Hennekens CH, Willett WC, Am J Clin Nutr 1999 69 890 897 10232627
37. Omega-6 fatty acids and risk for cardiovascular disease: a science advisory from the American Heart Association Nutrition Subcommittee of the Council on Nutrition, Physical Activity, and Metabolism; Council on Cardiovascular Nursing; and Council on Epidemiology and Prevention. Harris WS, Mozaffarian D, Rimm E, Kris-Etherton P, Rudel LL, Appel LJ, Engler MM, Engler MB, Sacks F, Circulation 2009 119 902 907 10.1161/CIRCULATIONAHA.108.191627 19171857
38. Importance of the ratio of omega-6/omega-3 essential fatty acids: evolutionary aspects. Simopoulos AP, World Rev Nutr Diet 2003 92 1 22 14579680