메뉴 건너뛰기




Volumn 34, Issue 13, 2014, Pages 2382-2395

Mechanism of action of phenethylisothiocyanate and other reactive oxygen species-inducing anticancer agents

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; MICRORNA; PHENETHYL ISOTHIOCYANATE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; TRANSCRIPTION FACTOR SP4;

EID: 84901752401     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01602-13     Document Type: Article
Times cited : (102)

References (47)
  • 1
    • 70350433460 scopus 로고    scopus 로고
    • Attacking cancer at its foundation
    • Lydon N. 2009. Attacking cancer at its foundation. Nat. Med. 15:1153-1157. http://dx.doi.org/10.1038/nm1009-1153.
    • (2009) Nat. Med. , vol.15 , pp. 1153-1157
    • Lydon, N.1
  • 2
    • 33847349283 scopus 로고    scopus 로고
    • Reactive oxygen species: a breath of life or death?
    • Fruehauf JP, Meyskens FL, Jr. 2007. Reactive oxygen species: a breath of life or death? Clin. Cancer Res. 13:789-794. http://dx.doi.org/10.1158/1078-0432.CCR-06-2082.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 789-794
    • Fruehauf, J.P.1    Meyskens Jr., F.L.2
  • 3
    • 67650071137 scopus 로고    scopus 로고
    • Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
    • Trachootham D, Alexandre J, Huang P. 2009. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat. Rev. Drug Discov. 8:579-591. http://dx.doi.org/10.1038/nrd2803.
    • (2009) Nat. Rev. Drug Discov. , vol.8 , pp. 579-591
    • Trachootham, D.1    Alexandre, J.2    Huang, P.3
  • 4
    • 27744557065 scopus 로고    scopus 로고
    • Oxidative stress and apoptosis: a new treatment paradigm in cancer
    • Engel RH, Evens AM. 2006. Oxidative stress and apoptosis: a new treatment paradigm in cancer. Front. Biosci. 11:300-312. http://dx.doi.org/10.2741/1798.
    • (2006) Front. Biosci. , vol.11 , pp. 300-312
    • Engel, R.H.1    Evens, A.M.2
  • 5
    • 33748165596 scopus 로고    scopus 로고
    • Reactive oxygen species in cancer cells: live by the sword, die by the sword
    • Schumacker PT. 2006. Reactive oxygen species in cancer cells: live by the sword, die by the sword. Cancer Cell 10:175-176. http://dx.doi.org/10.1016/j.ccr.2006.08.015.
    • (2006) Cancer Cell , vol.10 , pp. 175-176
    • Schumacker, P.T.1
  • 6
    • 80052024865 scopus 로고    scopus 로고
    • Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasomedependent and-independent downregulation of specificity proteins (Sp) transcription factors
    • Chintharlapalli S, Papineni S, Lei P, Pathi S, Safe S. 2011. Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasomedependent and-independent downregulation of specificity proteins (Sp) transcription factors. BMC Cancer 11:371. http://dx.doi.org/10.1186/1471-2407-11-371.
    • (2011) BMC Cancer , vol.11 , pp. 371
    • Chintharlapalli, S.1    Papineni, S.2    Lei, P.3    Pathi, S.4    Safe, S.5
  • 7
    • 79951831653 scopus 로고    scopus 로고
    • GT-094, a NO-NSAID, inhibits colon cancer cell growth by activation of a reactive oxygen species-microRNA-27a: ZBTB10-specificity protein pathway
    • Pathi SS, Jutooru I, Chadalapaka G, Sreevalsan S, Anand S, Thatcher GR, Safe S. 2011. GT-094, a NO-NSAID, inhibits colon cancer cell growth by activation of a reactive oxygen species-microRNA-27a: ZBTB10-specificity protein pathway. Mol. Cancer Res. 9:195-202. http://dx.doi.org/10.1158/1541-7786.MCR-10-0363.
    • (2011) Mol. Cancer Res. , vol.9 , pp. 195-202
    • Pathi, S.S.1    Jutooru, I.2    Chadalapaka, G.3    Sreevalsan, S.4    Anand, S.5    Thatcher, G.R.6    Safe, S.7
  • 8
    • 77954934314 scopus 로고    scopus 로고
    • Methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of microRNA-27a
    • Jutooru I, Chadalapaka G, Abdelrahim M, Basha MR, Samudio I, Konopleva M, Andreeff M, Safe S. 2010. Methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of microRNA-27a. Mol. Pharmacol. 78:226-236. http://dx.doi.org/10.1124/mol.110.064451.
    • (2010) Mol. Pharmacol. , vol.78 , pp. 226-236
    • Jutooru, I.1    Chadalapaka, G.2    Abdelrahim, M.3    Basha, M.R.4    Samudio, I.5    Konopleva, M.6    Andreeff, M.7    Safe, S.8
  • 9
    • 84859572083 scopus 로고    scopus 로고
    • Celastrol decreases specificity proteins (Sp) and fibroblast growth factor receptor-3 (FGFR3) in bladder cancer cells
    • Chadalapaka G, Jutooru I, Safe S. 2012. Celastrol decreases specificity proteins (Sp) and fibroblast growth factor receptor-3 (FGFR3) in bladder cancer cells. Carcinogenesis 33:886-894. http://dx.doi.org/10.1093/carcin/bgs102.
    • (2012) Carcinogenesis , vol.33 , pp. 886-894
    • Chadalapaka, G.1    Jutooru, I.2    Safe, S.3
  • 10
    • 77953812438 scopus 로고    scopus 로고
    • Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth
    • Jutooru I, Chadalapaka G, Sreevalsan S, Lei P, Barhoumi R, Burghardt R, Safe S. 2010. Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth. Exp. Cell Res. 316:2174-2188. http://dx.doi.org/10.1016/j.yexcr.2010.04.027.
    • (2010) Exp. Cell Res. , vol.316 , pp. 2174-2188
    • Jutooru, I.1    Chadalapaka, G.2    Sreevalsan, S.3    Lei, P.4    Barhoumi, R.5    Burghardt, R.6    Safe, S.7
  • 11
    • 77955506109 scopus 로고    scopus 로고
    • Inhibition of NFkappaB and pancreatic cancer cell and tumor growth by curcumin is dependent on specificity protein down-regulation
    • Jutooru I, Chadalapaka G, Lei P, Safe S. 2010. Inhibition of NFkappaB and pancreatic cancer cell and tumor growth by curcumin is dependent on specificity protein down-regulation. J. Biol. Chem. 285:25332-25344. http://dx.doi.org/10.1074/jbc.M109.095240.
    • (2010) J. Biol. Chem. , vol.285 , pp. 25332-25344
    • Jutooru, I.1    Chadalapaka, G.2    Lei, P.3    Safe, S.4
  • 12
    • 80053630206 scopus 로고    scopus 로고
    • Pharmacologic doses of ascorbic acid repress specificity protein (Sp) transcription factors and Sp-regulated genes in colon cancer cells
    • Pathi SS, Lei P, Sreevalsan S, Chadalapaka G, Jutooru I, Safe S. 2011. Pharmacologic doses of ascorbic acid repress specificity protein (Sp) transcription factors and Sp-regulated genes in colon cancer cells. Nutr. Cancer 63:1133-1142. http://dx.doi.org/10.1080/01635581.2011.605984.
    • (2011) Nutr. Cancer , vol.63 , pp. 1133-1142
    • Pathi, S.S.1    Lei, P.2    Sreevalsan, S.3    Chadalapaka, G.4    Jutooru, I.5    Safe, S.6
  • 13
    • 0035527472 scopus 로고    scopus 로고
    • Cruciferous vegetables and cancer prevention
    • Murillo G, Mehta RG. 2001. Cruciferous vegetables and cancer prevention. Nutr. Cancer 41:17-28. http://dx.doi.org/10.1080/01635581.2001.9680607.
    • (2001) Nutr. Cancer , vol.41 , pp. 17-28
    • Murillo, G.1    Mehta, R.G.2
  • 14
    • 0034606676 scopus 로고    scopus 로고
    • Fruit and vegetable intakes and prostate cancer risk
    • Cohen JH, Kristal AR, Stanford JL. 2000. Fruit and vegetable intakes and prostate cancer risk. J. Natl. Cancer Inst. 92:61-68. http://dx.doi.org/10.1093/jnci/92.1.61.
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 61-68
    • Cohen, J.H.1    Kristal, A.R.2    Stanford, J.L.3
  • 15
    • 59749104966 scopus 로고    scopus 로고
    • The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate
    • Sahu RP, Srivastava SK. 2009. The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate. J. Natl. Cancer Inst. 101:176-193. http://dx.doi.org/10.1093/jnci/djn470.
    • (2009) J. Natl. Cancer Inst. , vol.101 , pp. 176-193
    • Sahu, R.P.1    Srivastava, S.K.2
  • 16
    • 22744440329 scopus 로고    scopus 로고
    • Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells
    • Xu C, Shen G, Chen C, Gelinas C, Kong AN. 2005. Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells. Oncogene 24:4486-4495. http://dx.doi.org/10.1038/sj.onc.1208656.
    • (2005) Oncogene , vol.24 , pp. 4486-4495
    • Xu, C.1    Shen, G.2    Chen, C.3    Gelinas, C.4    Kong, A.N.5
  • 18
    • 33644869673 scopus 로고    scopus 로고
    • Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with beta-phenylethyl isothiocyanate and curcumin
    • Kim JH, Xu C, Keum YS, Reddy B, Conney A, Kong AN. 2006. Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with beta-phenylethyl isothiocyanate and curcumin. Carcinogenesis 27:475-482. http://dx.doi.org/10.1093/carcin/bgi272.
    • (2006) Carcinogenesis , vol.27 , pp. 475-482
    • Kim, J.H.1    Xu, C.2    Keum, Y.S.3    Reddy, B.4    Conney, A.5    Kong, A.N.6
  • 19
    • 77955072957 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways
    • Yang MD, Lai KC, Lai TY, Hsu SC, Kuo CL, Yu CS, Lin ML, Yang JS, Kuo HM, Wu SH, Chung JG. 2010. Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways. Anticancer Res. 30: 2135-2143.
    • (2010) Anticancer Res. , vol.30 , pp. 2135-2143
    • Yang, M.D.1    Lai, K.C.2    Lai, T.Y.3    Hsu, S.C.4    Kuo, C.L.5    Yu, C.S.6    Lin, M.L.7    Yang, J.S.8    Kuo, H.M.9    Wu, S.H.10    Chung, J.G.11
  • 20
    • 77949351356 scopus 로고    scopus 로고
    • Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway
    • Lai KC, Huang AC, Hsu SC, Kuo CL, Yang JS, Wu SH, Chung JG. 2010. Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway. J. Agric. Food Chem. 58:2935-2942. http://dx.doi.org/10.1021/jf9036694.
    • (2010) J. Agric. Food Chem. , vol.58 , pp. 2935-2942
    • Lai, K.C.1    Huang, A.C.2    Hsu, S.C.3    Kuo, C.L.4    Yang, J.S.5    Wu, S.H.6    Chung, J.G.7
  • 21
    • 0142185392 scopus 로고    scopus 로고
    • Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits growth of PC-3 human prostate cancer xenografts in vivo
    • Srivastava SK, Xiao D, Lew KL, Hershberger P, Kokkinakis DM, Johnson CS, Trump DL, Singh SV. 2003. Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits growth of PC-3 human prostate cancer xenografts in vivo. Carcinogenesis 24:1665-1670. http://dx.doi.org/10.1093/carcin/bgg123.
    • (2003) Carcinogenesis , vol.24 , pp. 1665-1670
    • Srivastava, S.K.1    Xiao, D.2    Lew, K.L.3    Hershberger, P.4    Kokkinakis, D.M.5    Johnson, C.S.6    Trump, D.L.7    Singh, S.V.8
  • 22
    • 33845221445 scopus 로고    scopus 로고
    • Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak
    • Xiao D, Vogel V, Singh SV. 2006. Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak. Mol. Cancer Ther. 5:2931-2945. http://dx.doi.org/10.1158/1535-7163.MCT-06-0396.
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 2931-2945
    • Xiao, D.1    Vogel, V.2    Singh, S.V.3
  • 23
    • 79952300263 scopus 로고    scopus 로고
    • Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3
    • Kim SH, Nagalingam A, Saxena NK, Singh SV, Sharma D. 2011. Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3. Carcinogenesis 32:359-367. http://dx.doi.org/10.1093/carcin/bgq267.
    • (2011) Carcinogenesis , vol.32 , pp. 359-367
    • Kim, S.H.1    Nagalingam, A.2    Saxena, N.K.3    Singh, S.V.4    Sharma, D.5
  • 24
    • 77952942731 scopus 로고    scopus 로고
    • Drugs that target specificity proteins downregulate epidermal growth factor receptor in bladder cancer cells
    • Chadalapaka G, Jutooru I, Burghardt R, Safe S. 2010. Drugs that target specificity proteins downregulate epidermal growth factor receptor in bladder cancer cells. Mol. Cancer Res. 8:739-750. http://dx.doi.org/10.1158/1541-7786.MCR-09-0493.
    • (2010) Mol. Cancer Res. , vol.8 , pp. 739-750
    • Chadalapaka, G.1    Jutooru, I.2    Burghardt, R.3    Safe, S.4
  • 26
    • 77956218104 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells
    • Xiao D, Powolny AA, Moura MB, Kelley EE, Bommareddy A, Kim SH, Hahm ER, Normolle D, Van Houten B, Singh SV. 2010. Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells. J. Biol. Chem. 285:26558-26569. http://dx.doi.org/10.1074/jbc.M109.063255.
    • (2010) J. Biol. Chem. , vol.285 , pp. 26558-26569
    • Xiao, D.1    Powolny, A.A.2    Moura, M.B.3    Kelley, E.E.4    Bommareddy, A.5    Kim, S.H.6    Hahm, E.R.7    Normolle, D.8    Van Houten, B.9    Singh, S.V.10
  • 27
    • 78651312053 scopus 로고    scopus 로고
    • Differential response of normal (PrEC) and cancerous human prostate cells (PC-3) to phenethyl isothiocyanatemediated changes in expression of antioxidant defense genes
    • Powolny AA, Singh SV. 2010. Differential response of normal (PrEC) and cancerous human prostate cells (PC-3) to phenethyl isothiocyanatemediated changes in expression of antioxidant defense genes. Pharm. Res. 27:2766-2775. http://dx.doi.org/10.1007/s11095-010-0278-4.
    • (2010) Pharm. Res. , vol.27 , pp. 2766-2775
    • Powolny, A.A.1    Singh, S.V.2
  • 28
    • 70349989502 scopus 로고    scopus 로고
    • Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells
    • Sahu RP, Zhang R, Batra S, Shi Y, Srivastava SK. 2009. Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells. Carcinogenesis 30:1744-1753. http://dx.doi.org/10.1093/carcin/bgp157.
    • (2009) Carcinogenesis , vol.30 , pp. 1744-1753
    • Sahu, R.P.1    Zhang, R.2    Batra, S.3    Shi, Y.4    Srivastava, S.K.5
  • 29
    • 23844505236 scopus 로고    scopus 로고
    • Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells
    • Tang L, Zhang Y. 2005. Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells. Mol. Cancer Ther. 4:1250-1259. http://dx.doi.org/10.1158/1535-7163.MCT-05-0041.
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 1250-1259
    • Tang, L.1    Zhang, Y.2
  • 30
    • 36349001297 scopus 로고    scopus 로고
    • The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells
    • Mertens-Talcott SU, Chintharlapalli S, Li X, Safe S. 2007. The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. Cancer Res. 67:11001-11011. http://dx.doi.org/10.1158/0008-5472.CAN-07-2416.
    • (2007) Cancer Res. , vol.67 , pp. 11001-11011
    • Mertens-Talcott, S.U.1    Chintharlapalli, S.2    Li, X.3    Safe, S.4
  • 32
    • 84875890253 scopus 로고    scopus 로고
    • HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer
    • Kim K, Jutooru I, Chadalapaka G, Johnson G, Frank J, Burghardt R, Kim S, Safe S. 2013. HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer. Oncogene 32:1616-1625. http://dx.doi.org/10.1038/onc.2012.193.
    • (2013) Oncogene , vol.32 , pp. 1616-1625
    • Kim, K.1    Jutooru, I.2    Chadalapaka, G.3    Johnson, G.4    Frank, J.5    Burghardt, R.6    Kim, S.7    Safe, S.8
  • 35
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • Lee Y, Kim M, Han J, Yeom KH, Lee S, Baek SH, Kim VN. 2004. MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 23: 4051-4060. http://dx.doi.org/10.1038/sj.emboj.7600385.
    • (2004) EMBO J. , vol.23 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3    Yeom, K.H.4    Lee, S.5    Baek, S.H.6    Kim, V.N.7
  • 36
    • 34047264639 scopus 로고    scopus 로고
    • Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
    • Woods K, Thomson JM, Hammond SM. 2007. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J. Biol. Chem. 282:2130-2134. http://dx.doi.org/10.1074/jbc.C600252200.
    • (2007) J. Biol. Chem. , vol.282 , pp. 2130-2134
    • Woods, K.1    Thomson, J.M.2    Hammond, S.M.3
  • 37
    • 73549124785 scopus 로고    scopus 로고
    • Tumorigenicity of the miR-17-92 cluster distilled
    • van Haaften G, Agami R. 2010. Tumorigenicity of the miR-17-92 cluster distilled. Genes Dev. 24:1-4. http://dx.doi.org/10.1101/gad.1887110.
    • (2010) Genes Dev. , vol.24 , pp. 1-4
    • van Haaften, G.1    Agami, R.2
  • 38
    • 0035933832 scopus 로고    scopus 로고
    • Cloning and characterization of the 5'-flanking region of the human transcription factor Sp1 gene
    • Nicolas M, Noe V, Jensen KB, Ciudad CJ. 2001. Cloning and characterization of the 5'-flanking region of the human transcription factor Sp1 gene. J. Biol. Chem. 276:22126-22132. http://dx.doi.org/10.1074/jbc.M010740200.
    • (2001) J. Biol. Chem. , vol.276 , pp. 22126-22132
    • Nicolas, M.1    Noe, V.2    Jensen, K.B.3    Ciudad, C.J.4
  • 39
    • 0348223971 scopus 로고    scopus 로고
    • Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer
    • Wang L, Wei D, Huang S, Peng Z, Le X, Wu TT, Yao J, Ajani J, Xie K. 2003. Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer. Clin. Cancer Res. 9:6371-6380.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 6371-6380
    • Wang, L.1    Wei, D.2    Huang, S.3    Peng, Z.4    Le, X.5    Wu, T.T.6    Yao, J.7    Ajani, J.8    Xie, K.9
  • 40
    • 3042570272 scopus 로고    scopus 로고
    • Association between expression of transcription factor Sp1 and increased vascular endothelial growth factor expression, advanced stage, and poor survival in patients with resected gastric cancer
    • Yao JC, Wang L, Wei D, Gong W, Hassan M, Wu TT, Mansfield P, Ajani J, Xie K. 2004. Association between expression of transcription factor Sp1 and increased vascular endothelial growth factor expression, advanced stage, and poor survival in patients with resected gastric cancer. Clin. Cancer Res. 10:4109-4117. http://dx.doi.org/10.1158/1078-0432.CCR-03-0628.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 4109-4117
    • Yao, J.C.1    Wang, L.2    Wei, D.3    Gong, W.4    Hassan, M.5    Wu, T.T.6    Mansfield, P.7    Ajani, J.8    Xie, K.9
  • 41
    • 53549129746 scopus 로고    scopus 로고
    • Sp1, a new biomarker that identifies a subset of aggressive pancreatic ductal adenocarcinoma
    • Jiang NY, Woda BA, Banner BF, Whalen GF, Dresser KA, Lu D. 2008. Sp1, a new biomarker that identifies a subset of aggressive pancreatic ductal adenocarcinoma. Cancer Epidemiol. Biomarkers Prev. 17:1648-1652. http://dx.doi.org/10.1158/1055-9965.EPI-07-2791.
    • (2008) Cancer Epidemiol. Biomarkers Prev. , vol.17 , pp. 1648-1652
    • Jiang, N.Y.1    Woda, B.A.2    Banner, B.F.3    Whalen, G.F.4    Dresser, K.A.5    Lu, D.6
  • 42
    • 13444267281 scopus 로고    scopus 로고
    • Down-regulation of overexpressed sp1 protein in human fibrosarcoma cell lines inhibits tumor formation
    • Lou Z, O'Reilly S, Liang H, Maher VM, Sleight SD, McCormick JJ. 2005. Down-regulation of overexpressed sp1 protein in human fibrosarcoma cell lines inhibits tumor formation. Cancer Res. 65:1007-1017.
    • (2005) Cancer Res. , vol.65 , pp. 1007-1017
    • Lou, Z.1    O'Reilly, S.2    Liang, H.3    Maher, V.M.4    Sleight, S.D.5    McCormick, J.J.6
  • 44
    • 3042752956 scopus 로고    scopus 로고
    • Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation?
    • Chiefari E, Brunetti A, Arturi F, Bidart JM, Russo D, Schlumberger M, Filetti S. 2002. Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation? BMC Cancer 2:35. http://dx.doi.org/10.1186/1471-2407-2-35.
    • (2002) BMC Cancer , vol.2 , pp. 35
    • Chiefari, E.1    Brunetti, A.2    Arturi, F.3    Bidart, J.M.4    Russo, D.5    Schlumberger, M.6    Filetti, S.7
  • 47
    • 84883460825 scopus 로고    scopus 로고
    • The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis
    • Noratto GD, Jutooru I, Safe S, Angel-Morales G, Mertens-Talcott SU. 2013. The drug resistance suppression induced by curcuminoids in colon cancer SW-480 cells is mediated by reactive oxygen species-induced disruption of the microRNA-27a-ZBTB10-Sp axis. Mol. Nutr. Food Res. 57:1638-1648. http://dx.doi.org/10.1002/mnfr.201200609.
    • (2013) Mol. Nutr. Food Res. , vol.57 , pp. 1638-1648
    • Noratto, G.D.1    Jutooru, I.2    Safe, S.3    Angel-Morales, G.4    Mertens-Talcott, S.U.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.