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Volumn 33, Issue 4, 2012, Pages 886-894

Celastrol decreases specificity proteins (Sp) and fibroblast growth factor receptor-3 (FGFR3) in bladder cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

CELASTROL; FIBROBLAST GROWTH FACTOR RECEPTOR 3; MICRORNA; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; TRANSCRIPTION FACTOR SP4;

EID: 84859572083     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgs102     Document Type: Article
Times cited : (56)

References (44)
  • 1
    • 77955635233 scopus 로고    scopus 로고
    • Cancer statistics, 2010
    • Jemal, A. et al. (2010) Cancer statistics, 2010. CA Cancer J. Clin., 60, 277-300.
    • (2010) CA Cancer J. Clin. , vol.60 , pp. 277-300
    • Jemal, A.1
  • 2
    • 66749102156 scopus 로고    scopus 로고
    • The development of multiple bladder tumour recurrences in relation to the FGFR3 mutation status of the primary tumour
    • Kompier, L. C. et al. (2009) The development of multiple bladder tumour recurrences in relation to the FGFR3 mutation status of the primary tumour. J. Pathol., 218, 104-112.
    • (2009) J. Pathol. , vol.218 , pp. 104-112
    • Kompier, L.C.1
  • 3
    • 0035495693 scopus 로고    scopus 로고
    • Locally advanced and metastatic bladder cancer
    • Dreicer, R. (2001) Locally advanced and metastatic bladder cancer. Curr. Treat. Options Oncol., 2, 431-436.
    • (2001) Curr. Treat. Options Oncol. , vol.2 , pp. 431-436
    • Dreicer, R.1
  • 4
    • 34147138418 scopus 로고    scopus 로고
    • Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in IFNalpha-sensitive and IFN-alpha-resistant human bladder cancer cells
    • Kamat, A. M. et al. (2007) Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in IFNalpha-sensitive and IFN-alpha-resistant human bladder cancer cells. Mol. Cancer Ther., 6, 1022-1030.
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 1022-1030
    • Kamat, A.M.1
  • 5
    • 0027051821 scopus 로고
    • Epidemiology of bladder cancer
    • Paneau, C. et al. (1992) [Epidemiology of bladder cancer]. Ann. Urol. (Paris), 26, 281-293.
    • (1992) Ann. Urol. (Paris) , vol.26 , pp. 281-293
    • Paneau, C.1
  • 6
    • 5144224183 scopus 로고    scopus 로고
    • Focus on bladder cancer
    • Dinney, C. P. et al. (2004) Focus on bladder cancer. Cancer Cell, 6, 111-116.
    • (2004) Cancer Cell , vol.6 , pp. 111-116
    • Dinney, C.P.1
  • 7
    • 31544464135 scopus 로고    scopus 로고
    • Inhibition of bladder tumor growth by 1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes: a new class of peroxisome proliferator-activated receptor gamma agonists
    • Kassouf, W. et al. (2006) Inhibition of bladder tumor growth by 1, 1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes: a new class of peroxisome proliferator-activated receptor gamma agonists. Cancer Res., 66, 412-418.
    • (2006) Cancer Res , vol.66 , pp. 412-418
    • Kassouf, W.1
  • 8
    • 48549085442 scopus 로고    scopus 로고
    • Curcumin decreases specificity protein expression in bladder cancer cells
    • Chadalapaka, G. et al. (2008) Curcumin decreases specificity protein expression in bladder cancer cells. Cancer Res., 68, 5345-5354.
    • (2008) Cancer Res , vol.68 , pp. 5345-5354
    • Chadalapaka, G.1
  • 9
    • 77952942731 scopus 로고    scopus 로고
    • Drugs that target specificity proteins downregulate epidermal growth factor receptor in bladder cancer cells
    • Chadalapaka, G. et al. (2010) Drugs that target specificity proteins downregulate epidermal growth factor receptor in bladder cancer cells. Mol. Cancer Res., 8, 739-750.
    • (2010) Mol. Cancer Res. , vol.8 , pp. 739-750
    • Chadalapaka, G.1
  • 10
    • 80054024030 scopus 로고    scopus 로고
    • Celastrol inhibits proliferation and induces chemosensitization through downregulation of NF-kappaB and STAT3 regulated gene products in multiple myeloma cells
    • Kannaiyan, R. et al. (2011) Celastrol inhibits proliferation and induces chemosensitization through downregulation of NF-kappaB and STAT3 regulated gene products in multiple myeloma cells. Br. J. Pharmacol., 164, 1506-1521.
    • (2011) Br. J. Pharmacol. , vol.164 , pp. 1506-1521
    • Kannaiyan, R.1
  • 11
    • 34548279788 scopus 로고    scopus 로고
    • Molecular understanding and modern application of traditional medicines: triumphs and trials
    • Corson, T. W. et al. (2007) Molecular understanding and modern application of traditional medicines: triumphs and trials. Cell, 130, 769-774.
    • (2007) Cell , vol.130 , pp. 769-774
    • Corson, T.W.1
  • 12
    • 78650733125 scopus 로고    scopus 로고
    • Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB
    • Dai, Y. et al. (2010) Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB. PLoS One, 5, e14153.
    • (2010) PLoS One , vol.5
    • Dai, Y.1
  • 13
    • 0032570693 scopus 로고    scopus 로고
    • Regulation of the fibroblast growth factor receptor 3 promoter and intron I enhancer by Sp1 family transcription factors
    • McEwen, D. G. et al. (1998) Regulation of the fibroblast growth factor receptor 3 promoter and intron I enhancer by Sp1 family transcription factors. J. Biol. Chem., 273, 5349-5357.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5349-5357
    • McEwen, D.G.1
  • 14
    • 42649088411 scopus 로고    scopus 로고
    • Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression
    • Huang, Y. et al. (2008) Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression. Cancer Lett., 264, 101-106.
    • (2008) Cancer Lett , vol.264 , pp. 101-106
    • Huang, Y.1
  • 15
    • 78549293218 scopus 로고    scopus 로고
    • Celastrol inhibits the growth of estrogen positive human breast cancer cells through modulation of estrogen receptor alpha
    • Jang, S. Y. et al. (2011) Celastrol inhibits the growth of estrogen positive human breast cancer cells through modulation of estrogen receptor alpha. Cancer Lett., 300, 57-65.
    • (2011) Cancer Lett. , vol.300 , pp. 57-65
    • Jang, S.Y.1
  • 16
    • 36749077060 scopus 로고    scopus 로고
    • Preclinical studies of celastrol and acetyl isogambogic acid in melanoma
    • Abbas, S. et al. (2007) Preclinical studies of celastrol and acetyl isogambogic acid in melanoma. Clin. Cancer Res., 13, 6769-6778.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 6769-6778
    • Abbas, S.1
  • 17
    • 77950234271 scopus 로고    scopus 로고
    • Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway
    • Pang, X. et al. (2010) Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway. Cancer Res., 70, 1951-1959.
    • (2010) Cancer Res. , vol.70 , pp. 1951-1959
    • Pang, X.1
  • 18
    • 77950818403 scopus 로고    scopus 로고
    • HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way
    • Peng, B. et al. (2010) HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way. Mol. Cancer, 9, 79.
    • (2010) Mol. Cancer , vol.9 , pp. 79
    • Peng, B.1
  • 19
    • 79955855304 scopus 로고    scopus 로고
    • Celastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells
    • Chen, G. et al. (2011) Celastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells. BMC Cancer, 11, 170.
    • (2011) BMC Cancer , vol.11 , pp. 170
    • Chen, G.1
  • 20
    • 33646406554 scopus 로고    scopus 로고
    • Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine" is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice
    • Yang, H. et al. (2006) Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine, " is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice. Cancer Res., 66, 4758-4765.
    • (2006) Cancer Res. , vol.66 , pp. 4758-4765
    • Yang, H.1
  • 21
    • 77954917015 scopus 로고    scopus 로고
    • Celastrol acts as a potent antimetastatic agent targeting beta1 integrin and inhibiting cell-extracellular matrix adhesion, in part via the p38 mitogen-activated protein kinase pathway
    • Zhu, H. et al. (2010) Celastrol acts as a potent antimetastatic agent targeting beta1 integrin and inhibiting cell-extracellular matrix adhesion, in part via the p38 mitogen-activated protein kinase pathway. J. Pharmacol. Exp. Ther., 334, 489-499.
    • (2010) J. Pharmacol. Exp. Ther. , vol.334 , pp. 489-499
    • Zhu, H.1
  • 22
    • 65549157628 scopus 로고    scopus 로고
    • Celastrol binds to ERK and inhibits FcepsilonRI signaling to exert an anti-allergic effect
    • Kim, Y. et al. (2009) Celastrol binds to ERK and inhibits FcepsilonRI signaling to exert an anti-allergic effect. Eur. J. Pharmacol., 612, 131-142.
    • (2009) Eur. J. Pharmacol. , vol.612 , pp. 131-142
    • Kim, Y.1
  • 23
    • 66349135677 scopus 로고    scopus 로고
    • Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice
    • Qing, J. et al. (2009) Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice. J. Clin. Invest., 119, 1216-1229.
    • (2009) J. Clin. Invest. , vol.119 , pp. 1216-1229
    • Qing, J.1
  • 24
    • 33745226490 scopus 로고    scopus 로고
    • Tolfenamic acid and pancreatic cancer growth, angiogenesis, and Sp protein degradation
    • Abdelrahim, M. et al. (2006) Tolfenamic acid and pancreatic cancer growth, angiogenesis, and Sp protein degradation. J. Natl. Cancer Inst., 98, 855-868.
    • (2006) J. Natl. Cancer Inst. , vol.98 , pp. 855-868
    • Abdelrahim, M.1
  • 25
    • 77954934314 scopus 로고    scopus 로고
    • Methyl 2-cyano-3, 12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of microRNA-27a
    • Jutooru, I. et al. (2010) Methyl 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of microRNA-27a. Mol. Pharmacol., 78, 226-236.
    • (2010) Mol. Pharmacol. , vol.78 , pp. 226-236
    • Jutooru, I.1
  • 26
    • 79951831653 scopus 로고    scopus 로고
    • GT-094, a NO-NSAID, inhibits colon cancer cell growth by activation of a reactive oxygen species-microRNA-27a: ZBTB10-specificity protein pathway
    • Pathi, S. S. et al. (2011) GT-094, a NO-NSAID, inhibits colon cancer cell growth by activation of a reactive oxygen species-microRNA-27a: ZBTB10-specificity protein pathway. Mol. Cancer Res., 9, 195-202.
    • (2011) Mol. Cancer Res. , vol.9 , pp. 195-202
    • Pathi, S.S.1
  • 27
    • 84857355139 scopus 로고    scopus 로고
    • Identification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancer
    • Kim, K. et al. (2012) Identification of oncogenic microRNA-17-92/ZBTB4/specificity protein axis in breast cancer. Oncogene., 31, 1034-1044.
    • (2012) Oncogene. , vol.31 , pp. 1034-1044
    • Kim, K.1
  • 28
    • 36349001297 scopus 로고    scopus 로고
    • The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells
    • Mertens-Talcott, S. U. et al. (2007) The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. Cancer Res., 67, 11001-11011.
    • (2007) Cancer Res , vol.67 , pp. 11001-11011
    • Mertens-Talcott, S.U.1
  • 29
    • 77953812438 scopus 로고    scopus 로고
    • Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth
    • Jutooru, I. et al. (2010) Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth. Exp. Cell Res., 316, 2174-2188.
    • (2010) Exp. Cell Res. , vol.316 , pp. 2174-2188
    • Jutooru, I.1
  • 30
    • 79951853010 scopus 로고    scopus 로고
    • Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer
    • Kannaiyan, R. et al. (2011) Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer. Cancer Lett., 303, 9-20.
    • (2011) Cancer Lett. , vol.303 , pp. 9-20
    • Kannaiyan, R.1
  • 31
    • 33749433916 scopus 로고    scopus 로고
    • Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators
    • Hieronymus, H. et al. (2006) Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators. Cancer Cell, 10, 321-330.
    • (2006) Cancer Cell , vol.10 , pp. 321-330
    • Hieronymus, H.1
  • 32
    • 38349153572 scopus 로고    scopus 로고
    • A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells
    • Zhang, T. et al. (2008) A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells. Mol. Cancer Ther., 7, 162-170.
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 162-170
    • Zhang, T.1
  • 33
    • 72149125851 scopus 로고    scopus 로고
    • Characterization of celastrol to inhibit hsp90 and cdc37 interaction
    • Zhang, T. et al. (2009) Characterization of celastrol to inhibit hsp90 and cdc37 interaction. J. Biol. Chem., 284, 35381-35389.
    • (2009) J. Biol. Chem. , vol.284 , pp. 35381-35389
    • Zhang, T.1
  • 34
    • 79957593454 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 (FGFR3) is a strong heat shock protein 90 (Hsp90) client: implications for therapeutic manipulation
    • Laederich, M. B. et al. (2011) Fibroblast growth factor receptor 3 (FGFR3) is a strong heat shock protein 90 (Hsp90) client: implications for therapeutic manipulation. J. Biol. Chem., 286, 19597-19604.
    • (2011) J. Biol. Chem. , vol.286 , pp. 19597-19604
    • Laederich, M.B.1
  • 35
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • Lee, Y. et al. (2004) MicroRNA genes are transcribed by RNA polymerase II. EMBO J., 23, 4051-4060.
    • (2004) EMBO J , vol.23 , pp. 4051-4060
    • Lee, Y.1
  • 36
    • 34047264639 scopus 로고    scopus 로고
    • Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
    • Woods, K. et al. (2007) Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J. Biol. Chem., 282, 2130-2134.
    • (2007) J. Biol. Chem. , vol.282 , pp. 2130-2134
    • Woods, K.1
  • 37
    • 52649153465 scopus 로고    scopus 로고
    • Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism
    • Trachootham, D. et al. (2008) Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism. Blood, 112, 1912-1922.
    • (2008) Blood , vol.112 , pp. 1912-1922
    • Trachootham, D.1
  • 38
    • 2842616065 scopus 로고    scopus 로고
    • Apoptosis induction in HL-60 cells and inhibition of topoisomerase II by triterpene celastrol
    • Nagase, M. et al. (2003) Apoptosis induction in HL-60 cells and inhibition of topoisomerase II by triterpene celastrol. Biosci. Biotechnol. Biochem., 67, 1883-1887.
    • (2003) Biosci. Biotechnol. Biochem. , vol.67 , pp. 1883-1887
    • Nagase, M.1
  • 39
    • 19944426549 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 is overexpressed in urinary tract carcinomas and modulates the neoplastic cell growth
    • Gomez-Roman, J. J. et al. (2005) Fibroblast growth factor receptor 3 is overexpressed in urinary tract carcinomas and modulates the neoplastic cell growth. Clin. Cancer Res., 11, 459-465.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 459-465
    • Gomez-Roman, J.J.1
  • 40
    • 34548407864 scopus 로고    scopus 로고
    • FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer
    • Tomlinson, D. C. et al. (2007) FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer. J. Pathol., 213, 91-98.
    • (2007) J. Pathol. , vol.213 , pp. 91-98
    • Tomlinson, D.C.1
  • 41
    • 0035866380 scopus 로고    scopus 로고
    • The fibroblast growth factor receptor 3 (FGFR3) mutation is a strong indicator of superficial bladder cancer with low recurrence rate
    • van Rhijn, B. W. et al. (2001) The fibroblast growth factor receptor 3 (FGFR3) mutation is a strong indicator of superficial bladder cancer with low recurrence rate. Cancer Res., 61, 1265-1268.
    • (2001) Cancer Res , vol.61 , pp. 1265-1268
    • van Rhijn, B.W.1
  • 42
    • 0036772919 scopus 로고    scopus 로고
    • Frequent FGFR3 mutations in urothelial papilloma
    • van Rhijn, B. W. et al. (2002) Frequent FGFR3 mutations in urothelial papilloma. J. Pathol., 198, 245-251.
    • (2002) J. Pathol. , vol.198 , pp. 245-251
    • van Rhijn, B.W.1
  • 43
    • 34047261665 scopus 로고    scopus 로고
    • Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors
    • Chintharlapalli, S. et al. (2007) Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors. Cancer Res., 67, 2816-2823.
    • (2007) Cancer Res , vol.67 , pp. 2816-2823
    • Chintharlapalli, S.1
  • 44
    • 0033583182 scopus 로고    scopus 로고
    • RIN ZF, a novel zinc finger gene, encodes proteins that bind to the CACC element of the gastrin promoter
    • Tillotson, L. G. (1999) RIN ZF, a novel zinc finger gene, encodes proteins that bind to the CACC element of the gastrin promoter. J. Biol. Chem., 274, 8123-8128.
    • (1999) J. Biol. Chem. , vol.274 , pp. 8123-8128
    • Tillotson, L.G.1


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