Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells

Carcinogenesis

Volumn 30, Issue 10, 2009, Pages 1744-1753

  Sahu, Ravi P ^a   Zhang, Ruifen ^a   Batra, Sanjay ^a   Shi, Yan ^a   Srivastava, Sanjay K ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; BENZYL ISOTHIOCYANATE; GLUTATHIONE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; THREONINE; TIRON; TYROSINE;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; ENZYME ACTIVATION; G2 PHASE; GLUTATHIONE; HUMANS; ISOTHIOCYANATES; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PANCREATIC NEOPLASMS; REACTIVE OXYGEN SPECIES; RNA, NEOPLASM; TRANSFECTION;

EID: 70349989502     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgp157     Document Type: Article

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