-
1
-
-
0016761686
-
Fatty liver: Biochemical and clinical considerations
-
Hoyumpa A. M. Jr, Greene H. L., Dunn G. D., Schenker S. Fatty liver: biochemical and clinical considerations. Am J Dig Dis: 1975; 20 12 1142 1170
-
(1975)
Am J Dig Dis
, vol.20
, Issue.12
, pp. 1142-1170
-
-
Hoyumpa Jr., A.M.1
Greene, H.L.2
Dunn, G.D.3
Schenker, S.4
-
2
-
-
20044374023
-
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
-
DOI 10.1002/hep.20701
-
Kleiner D. E., Brunt E. M., Van Natta M., et al. Nonalcoholic Steatohepatitis Clinical Research Network. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology: 2005; 41 6 1313 1321 (Pubitemid 40770284)
-
(2005)
Hepatology
, vol.41
, Issue.6
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
Behling, C.4
Contos, M.J.5
Cummings, O.W.6
Ferrell, L.D.7
Liu, Y.-C.8
Torbenson, M.S.9
Unalp-Arida, A.10
Yeh, M.11
McCullough, A.J.12
Sanyal, A.J.13
-
3
-
-
34548306754
-
Noninvasive diagnosis and monitoring of nonalcoholic steatohepatitis: Present and future
-
DOI 10.1002/hep.21768
-
Wieckowska A., McCullough A. J., Feldstein A. E. Noninvasive diagnosis and monitoring of nonalcoholic steatohepatitis: present and future. Hepatology: 2007; 46 2 582 589 (Pubitemid 47344794)
-
(2007)
Hepatology
, vol.46
, Issue.2
, pp. 582-589
-
-
Wieckowska, A.1
McCullough, A.J.2
Feldstein, A.E.3
-
4
-
-
0038644536
-
Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference
-
DOI 10.1053/jhep.2003.50193
-
Neuschwander-Tetri B. A., Caldwell S. H. Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference. Hepatology: 2003; 37 5 1202 1219 (Pubitemid 36538699)
-
(2003)
Hepatology
, vol.37
, Issue.5
, pp. 1202-1219
-
-
Neuschwander-Tetri, B.A.1
Caldwell, S.H.2
-
5
-
-
77951431191
-
Is oil red-O staining and digital image analysis the gold standard for quantifying steatosis in the liver
-
author reply 1859-1860
-
Levene A. P., Kudo H., Thursz M. R., Anstee Q. M., Goldin R. D. Is oil red-O staining and digital image analysis the gold standard for quantifying steatosis in the liver? Hepatology: 2010; 51 5 1859, author reply 1859-1860
-
(2010)
Hepatology
, vol.51
, Issue.5
, pp. 1859
-
-
Levene, A.P.1
Kudo, H.2
Thursz, M.R.3
Anstee, Q.M.4
Goldin, R.D.5
-
6
-
-
0033982172
-
Prevalence of and risk factors for hepatic steatosis in northern Italy
-
Bellentani S., Saccoccio G., Masutti F., et al. Prevalence of and risk factors for hepatic steatosis in Northern Italy. Ann Intern Med: 2000; 132 2 112 117 (Pubitemid 30044177)
-
(2000)
Annals of Internal Medicine
, vol.132
, Issue.2
, pp. 112-117
-
-
Bellentani, S.1
Saccoccio, G.2
Masutti, F.3
Croce, L.S.4
Brandi, G.5
Sasso, F.6
Cristanini, G.7
Tiribelli, C.8
-
7
-
-
4143100133
-
Non-alcoholic steatohepatitis in type 2 diabetes mellitus
-
DOI 10.1111/j.1440-1746.2004.03312.x
-
Gupte P., Amarapurkar D., Agal S., et al. Non-alcoholic steatohepatitis in type 2 diabetes mellitus. J Gastroenterol Hepatol: 2004; 19 8 854 858 (Pubitemid 39093200)
-
(2004)
Journal of Gastroenterology and Hepatology
, vol.19
, Issue.8
, pp. 854-858
-
-
Gupte, P.1
Amarapurkar, D.2
Agal, S.3
Baijal, R.4
Kulshrestha, P.5
Pramanik, S.6
Patel, N.7
Madan, A.8
Amarapurkar, A.9
Hafeezunnisa10
-
8
-
-
0019152816
-
Nonalcoholic steatohepatitis. Mayo Clinic experiences with a hitherto unnamed disease
-
Ludwig J., Viggiano T. R., McGill D. B., Oh B. J. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc: 1980; 55 7 434 438 (Pubitemid 10057164)
-
(1980)
Mayo Clinic Proceedings
, vol.55
, Issue.7
, pp. 434-438
-
-
Ludwig, J.1
Viggiano, T.R.2
McGill, D.B.3
Ott, B.J.4
-
9
-
-
0035083842
-
Nonalcoholic steatohepatitis: Definition and pathology
-
Brunt E. M. Nonalcoholic steatohepatitis: definition and pathology. Semin Liver Dis: 2001; 21 1 3 16 (Pubitemid 32240482)
-
(2001)
Seminars in Liver Disease
, vol.21
, Issue.1
, pp. 3-16
-
-
Brunt, E.M.1
-
10
-
-
84874115065
-
Hepatocyte senescence predicts progression in non-alcohol-related fatty liver disease
-
Aravinthan A., Scarpini C., Tachtatzis P., et al. Hepatocyte senescence predicts progression in non-alcohol-related fatty liver disease. J Hepatol: 2013; 58 3 549 556
-
(2013)
J Hepatol
, vol.58
, Issue.3
, pp. 549-556
-
-
Aravinthan, A.1
Scarpini, C.2
Tachtatzis, P.3
-
12
-
-
48649110854
-
The role of fatty acids in the development and progression of nonalcoholic fatty liver disease
-
Gentile C. L., Pagliassotti M. J. The role of fatty acids in the development and progression of nonalcoholic fatty liver disease. J Nutr Biochem: 2008; 19 9 567 576
-
(2008)
J Nutr Biochem
, vol.19
, Issue.9
, pp. 567-576
-
-
Gentile, C.L.1
Pagliassotti, M.J.2
-
13
-
-
84857539784
-
Effect of intracellular lipid accumulation in a new model of non-alcoholic fatty liver disease
-
Chavez-Tapia N. C., Rosso N., Tiribelli C. Effect of intracellular lipid accumulation in a new model of non-alcoholic fatty liver disease. BMC Gastroenterol: 2012; 12 20
-
(2012)
BMC Gastroenterol
, vol.12
, pp. 20
-
-
Chavez-Tapia, N.C.1
Rosso, N.2
Tiribelli, C.3
-
14
-
-
84872493396
-
Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis
-
Musso G., Gambino R., Cassader M. Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis. Prog Lipid Res: 2013; 52 1 175 191
-
(2013)
Prog Lipid Res
, vol.52
, Issue.1
, pp. 175-191
-
-
Musso, G.1
Gambino, R.2
Cassader, M.3
-
15
-
-
84876803994
-
Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis
-
Ioannou G. N., Haigh W. G., Thorning D., Savard C. Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis. J Lipid Res: 2013; 54 5 1326 1334
-
(2013)
J Lipid Res
, vol.54
, Issue.5
, pp. 1326-1334
-
-
Ioannou, G.N.1
Haigh, W.G.2
Thorning, D.3
Savard, C.4
-
16
-
-
79951633215
-
Does hepatic steatosis affect drug metabolizing enzymes in the liver
-
Buechler C., Weiss T. S. Does hepatic steatosis affect drug metabolizing enzymes in the liver? Curr Drug Metab: 2011; 12 1 24 34
-
(2011)
Curr Drug Metab
, vol.12
, Issue.1
, pp. 24-34
-
-
Buechler, C.1
Weiss, T.S.2
-
18
-
-
0028817865
-
Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B
-
McKenzie R., Fried M. W., Sallie R., et al. Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B. N Engl J Med: 1995; 333 17 1099 1105
-
(1995)
N Engl J Med
, vol.333
, Issue.17
, pp. 1099-1105
-
-
McKenzie, R.1
Fried, M.W.2
Sallie, R.3
-
19
-
-
0030997076
-
Histopathologic changes associated with fialuridine hepatotoxicity
-
Kleiner D. E., Gaffey M. J., Sallie R., et al. Histopathologic changes associated with fialuridine hepatotoxicity. Mod Pathol: 1997; 10 3 192 199 (Pubitemid 27130467)
-
(1997)
Modern Pathology
, vol.10
, Issue.3
, pp. 192-199
-
-
Kleiner, D.E.1
Gaffey, M.J.2
Sallie, R.3
Tsokos, M.4
Nichols, L.5
McKenzie, R.6
Straus, S.E.7
Hoofnagle, J.H.8
-
20
-
-
8544249855
-
Mitochondrial injury. Lessons from the fialuridine trial
-
Honkoop P., Scholte H. R., de Man R. A., Schalm S. W. Mitochondrial injury. Lessons from the fialuridine trial. Drug Saf: 1997; 17 1 1 7 (Pubitemid 27367719)
-
(1997)
Drug Safety
, vol.17
, Issue.1
, pp. 1-7
-
-
Honfcoop, P.1
Scholte, H.R.2
De Man, R.A.3
Schalm, S.W.4
-
21
-
-
1042301403
-
Mitochondrial Expression of the Human Equilibrative Nucleoside Transporter 1 (hENT1) Results in Enhanced Mitochondrial Toxicity of Antiviral Drugs
-
DOI 10.1074/jbc.M307938200
-
Lai Y., Tse C. M., Unadkat J. D. Mitochondrial expression of the human equilibrative nucleoside transporter 1 (hENT1) results in enhanced mitochondrial toxicity of antiviral drugs. J Biol Chem: 2004; 279 6 4490 4497 (Pubitemid 38199039)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.6
, pp. 4490-4497
-
-
Lai, Y.1
Tse, C.-M.2
Unadkat, J.D.3
-
22
-
-
70249107777
-
Cytometric analysis for drug-induced steatosis in HepG2 cells
-
Donato M. T., Martínez-Romero A., Jiménez N., et al. Cytometric analysis for drug-induced steatosis in HepG2 cells. Chem Biol Interact: 2009; 181 3 417 423
-
(2009)
Chem Biol Interact
, vol.181
, Issue.3
, pp. 417-423
-
-
Donato, M.T.1
Martínez-Romero, A.2
Jiménez, N.3
-
23
-
-
65649112138
-
In vitro assay for drug-induced hepatosteatosis using rat primary hepatocytes, a fluorescent lipid analog and gene expression analysis
-
Fujimura H., Murakami N., Kurabe M., Toriumi W. In vitro assay for drug-induced hepatosteatosis using rat primary hepatocytes, a fluorescent lipid analog and gene expression analysis. J Appl Toxicol: 2009; 29 4 356 363
-
(2009)
J Appl Toxicol
, vol.29
, Issue.4
, pp. 356-363
-
-
Fujimura, H.1
Murakami, N.2
Kurabe, M.3
Toriumi, W.4
-
24
-
-
85033532182
-
Tetracycline-induced steatosis in primary canine hepatocyte cultures
-
Amacher D. E., Martin B. A. Tetracycline-induced steatosis in primary canine hepatocyte cultures. Fundam Appl Toxicol: 1997; 40 2 256 263
-
(1997)
Fundam Appl Toxicol
, vol.40
, Issue.2
, pp. 256-263
-
-
Amacher, D.E.1
Martin, B.A.2
-
25
-
-
84863682662
-
Phospholipogenic pharmaceuticals are associated with a higher incidence of histological findings than nonphospholipogenic pharmaceuticals in preclinical toxicology studies
-
Article ID 308594
-
Barone L. R., Boyer S., Damewood J. R. Jr, Fikes J., Ciaccio P. J. Phospholipogenic pharmaceuticals are associated with a higher incidence of histological findings than nonphospholipogenic pharmaceuticals in preclinical toxicology studies. J Toxicol: 2012; 2012: Article ID 308594
-
(2012)
J Toxicol
, Issue.2012
-
-
Barone, L.R.1
Boyer, S.2
Damewood Jr., J.R.3
Fikes, J.4
Ciaccio, P.J.5
-
26
-
-
77951212394
-
Phospholipidosis as a function of basicity, lipophilicity, and volume of distribution of compounds
-
Hanumegowda U. M., Wenke G., Regueiro-Ren A., Yordanova R., Corradi J. P., Adams S. P. Phospholipidosis as a function of basicity, lipophilicity, and volume of distribution of compounds. Chem Res Toxicol: 2010; 23 4 749 755
-
(2010)
Chem Res Toxicol
, vol.23
, Issue.4
, pp. 749-755
-
-
Hanumegowda, U.M.1
Wenke, G.2
Regueiro-Ren, A.3
Yordanova, R.4
Corradi, J.P.5
Adams, S.P.6
-
27
-
-
33749128073
-
Drug-induced phospholipidosis: Issues and future directions
-
DOI 10.1517/14740338.5.4.567
-
Reasor M. J., Hastings K. L., Ulrich R. G. Drug-induced phospholipidosis: issues and future directions. Expert Opin Drug Saf: 2006; 5 4 567 583 (Pubitemid 44468453)
-
(2006)
Expert Opinion on Drug Safety
, vol.5
, Issue.4
, pp. 567-583
-
-
Reasor, M.J.1
Hastings, K.L.2
Ulrich, R.G.3
-
28
-
-
0025572278
-
Cationic amphiphilic drugs and phospholipid storage disorder
-
Kodavanti U. P., Mehendale H. M. Cationic amphiphilic drugs and phospholipid storage disorder. Pharmacol Rev: 1990; 42 4 327 354
-
(1990)
Pharmacol Rev
, vol.42
, Issue.4
, pp. 327-354
-
-
Kodavanti, U.P.1
Mehendale, H.M.2
-
29
-
-
84868105756
-
Identification of drugs inducing phospholipidosis by novel in vitro data
-
Muehlbacher M., Tripal P., Roas F., Kornhuber J. Identification of drugs inducing phospholipidosis by novel in vitro data. ChemMedChem: 2012; 7 11 1925 1934
-
(2012)
ChemMedChem
, vol.7
, Issue.11
, pp. 1925-1934
-
-
Muehlbacher, M.1
Tripal, P.2
Roas, F.3
Kornhuber, J.4
-
30
-
-
84876725644
-
In silico modeling to predict drug-induced phospholipidosis
-
Choi S. S., Kim J. S., Valerio L. G. Jr, Sadrieh N. In silico modeling to predict drug-induced phospholipidosis. Toxicol Appl Pharmacol: 2013; 269 2 195 204
-
(2013)
Toxicol Appl Pharmacol
, vol.269
, Issue.2
, pp. 195-204
-
-
Choi, S.S.1
Kim, J.S.2
Valerio Jr., L.G.3
Sadrieh, N.4
-
31
-
-
0035082455
-
Peroxisomal beta-oxidation and steatohepatitis
-
Rao M. S., Reddy J. K. Peroxisomal beta-oxidation and steatohepatitis. Semin Liver Dis: 2001; 21 1 43 55
-
(2001)
Semin Liver Dis
, vol.21
, Issue.1
, pp. 43-55
-
-
Rao, M.S.1
Reddy, J.K.2
-
32
-
-
85027952816
-
Role of lipid droplet proteins in liver steatosis
-
Okumura T. Role of lipid droplet proteins in liver steatosis. J Physiol Biochem: 2011; 67 4 629 636
-
(2011)
J Physiol Biochem
, vol.67
, Issue.4
, pp. 629-636
-
-
Okumura, T.1
-
33
-
-
46249097997
-
Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis
-
DOI 10.1002/hep.22268
-
Straub B. K., Stoeffel P., Heid H., Zimbelmann R., Schirmacher P. Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis. Hepatology: 2008; 47 6 1936 1946 (Pubitemid 351945561)
-
(2008)
Hepatology
, vol.47
, Issue.6
, pp. 1936-1946
-
-
Straub, B.K.1
Stoeffel, P.2
Heid, H.3
Zimbelmann, R.4
Schirmacher, P.5
-
34
-
-
55949124005
-
Drug-induced liver injury through mitochondrial dysfunction: Mechanisms and detection during preclinical safety studies
-
Labbe G., Pessayre D., Fromenty B. Drug-induced liver injury through mitochondrial dysfunction: mechanisms and detection during preclinical safety studies. Fundam Clin Pharmacol: 2008; 22 4 335 353
-
(2008)
Fundam Clin Pharmacol
, vol.22
, Issue.4
, pp. 335-353
-
-
Labbe, G.1
Pessayre, D.2
Fromenty, B.3
-
35
-
-
77958196146
-
Activation of the aryl hydrocarbon receptor induces hepatic steatosis via the upregulation of fatty acid transport
-
Kawano Y., Nishiumi S., Tanaka S., et al. Activation of the aryl hydrocarbon receptor induces hepatic steatosis via the upregulation of fatty acid transport. Arch Biochem Biophys: 2010; 504 2 221 227
-
(2010)
Arch Biochem Biophys
, vol.504
, Issue.2
, pp. 221-227
-
-
Kawano, Y.1
Nishiumi, S.2
Tanaka, S.3
-
36
-
-
4043077961
-
Molecular mediators of hepatic steatosis and liver injury
-
DOI 10.1172/JCI200422422
-
Browning J. D., Horton J. D. Molecular mediators of hepatic steatosis and liver injury. J Clin Invest: 2004; 114 2 147 152 (Pubitemid 39071617)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.2
, pp. 147-152
-
-
Browning, J.D.1
Horton, J.D.2
-
37
-
-
79952702137
-
Drug-induced toxicity on mitochondria and lipid metabolism: Mechanistic diversity and deleterious consequences for the liver
-
Begriche K., Massart J., Robin M. A., Borgne-Sanchez A., Fromenty B. Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver. J Hepatol: 2011; 54 4 773 794
-
(2011)
J Hepatol
, vol.54
, Issue.4
, pp. 773-794
-
-
Begriche, K.1
Massart, J.2
Robin, M.A.3
Borgne-Sanchez, A.4
Fromenty, B.5
-
39
-
-
0026065267
-
Alcoholic liver disease: Pathologic, pathogenetic and clinical aspects
-
Ishak K. G., Zimmerman H. J., Ray M. B. Alcoholic liver disease: pathologic, pathogenetic and clinical aspects. Alcohol Clin Exp Res: 1991; 15 1 45 66
-
(1991)
Alcohol Clin Exp Res
, vol.15
, Issue.1
, pp. 45-66
-
-
Ishak, K.G.1
Zimmerman, H.J.2
Ray, M.B.3
-
40
-
-
0036163759
-
Mechanisms of hepatotoxicity
-
DOI 10.1093/toxsci/65.2.166
-
Jaeschke H., Gores G. J., Cederbaum A. I., Hinson J. A., Pessayre D., Lemasters J. J. Mechanisms of hepatotoxicity. Toxicol Sci: 2002; 65 2 166 176 (Pubitemid 34121108)
-
(2002)
Toxicological Sciences
, vol.65
, Issue.2
, pp. 166-176
-
-
Jaeschke, H.1
Gores, G.J.2
Cederbaum, A.I.3
Hinson, J.A.4
Pessayre, D.5
Lemasters, J.J.6
-
41
-
-
3342896519
-
Microvesicular steatosis induced by a short chain fatty acid: Effects on mitochondrial function and correlation with gene expression
-
DOI 10.1080/01926230490451699
-
Jolly R. A., Ciurlionis R., Morfitt D., et al. Microvesicular steatosis induced by a short chain fatty acid: effects on mitochondrial function and correlation with gene expression. Toxicol Pathol: 2004; 32 02 19 25 (Pubitemid 38993912)
-
(2004)
Toxicologic Pathology
, vol.32
, Issue.SUPPL. 2
, pp. 19-25
-
-
Jolly, R.A.1
Ciurlionis, R.2
Morfitt, D.3
Helgren, M.4
Patterson, R.5
Ulrich, R.G.6
Waring, J.F.7
-
42
-
-
25844445911
-
Fatty liver and drugs
-
Grieco A., Forgione A., Miele L., et al. Fatty liver and drugs. Eur Rev Med Pharmacol Sci: 2005; 9 5 261 263 (Pubitemid 41387388)
-
(2005)
European Review for Medical and Pharmacological Sciences
, vol.9
, Issue.5
, pp. 261-263
-
-
Grieco, A.1
Forgione, A.2
Miele, L.3
Vero, V.4
Greco, A.V.5
Gasbarrini, A.6
Gasbarrini, G.7
-
43
-
-
74949105745
-
Amiodarone hepatotoxicity in the context of the metabolic syndrome and right-sided heart failure
-
Mattar W., Juliar B., Gradus-Pizlo I., Kwo P. Y. Amiodarone hepatotoxicity in the context of the metabolic syndrome and right-sided heart failure. J Gastrointestin Liver Dis: 2009; 18 4 419 423
-
(2009)
J Gastrointestin Liver Dis
, vol.18
, Issue.4
, pp. 419-423
-
-
Mattar, W.1
Juliar, B.2
Gradus-Pizlo, I.3
Kwo, P.Y.4
-
45
-
-
0037364074
-
Tamoxifen: A most unlikely pioneering medicine
-
DOI 10.1038/nrd1031
-
Jordan V. C. Tamoxifen: a most unlikely pioneering medicine. Nat Rev Drug Discov: 2003; 2 3 205 213 (Pubitemid 37361665)
-
(2003)
Nature Reviews Drug Discovery
, vol.2
, Issue.3
, pp. 205-213
-
-
Jordan, V.C.1
-
46
-
-
68549109590
-
The association of nonalcoholic steatohepatitis and tamoxifen in patients with breast cancer
-
Saphner T., Triest-Robertson S., Li H., Holzman P. The association of nonalcoholic steatohepatitis and tamoxifen in patients with breast cancer. Cancer: 2009; 115 14 3189 3195
-
(2009)
Cancer
, vol.115
, Issue.14
, pp. 3189-3195
-
-
Saphner, T.1
Triest-Robertson, S.2
Li, H.3
Holzman, P.4
-
47
-
-
0035131855
-
Relationships between tamoxifen use, liver fat and body fat distribution in women with breast cancer
-
Nguyen M. C., Stewart R. B., Banerji M. A., Gordon D. H., Kral J. G. Relationships between tamoxifen use, liver fat and body fat distribution in women with breast cancer. Int J Obes Relat Metab Disord: 2001; 25 2 296 298
-
(2001)
Int J Obes Relat Metab Disord
, vol.25
, Issue.2
, pp. 296-298
-
-
Nguyen, M.C.1
Stewart, R.B.2
Banerji, M.A.3
Gordon, D.H.4
Kral, J.G.5
-
48
-
-
20244370881
-
Incidence and risk factors for non-alcoholic steatohepatitis: Prospective study of 5408 women enrolled in Italian tamoxifen chemoprevention trial
-
Bruno S., Maisonneuve P., Castellana P., et al. Incidence and risk factors for non-alcoholic steatohepatitis: prospective study of 5408 women enrolled in Italian tamoxifen chemoprevention trial. BMJ: 2005; 330 7497 932
-
(2005)
BMJ
, vol.330
, Issue.7497
, pp. 932
-
-
Bruno, S.1
Maisonneuve, P.2
Castellana, P.3
-
49
-
-
34247203727
-
Tamoxifen inhibits topoisomerases, depletes mitochondrial DNA, and triggers steatosis in mouse liver
-
DOI 10.1124/jpet.106.114546
-
Larosche I., Lettéron P., Fromenty B., et al. Tamoxifen inhibits topoisomerases, depletes mitochondrial DNA, and triggers steatosis in mouse liver. J Pharmacol Exp Ther: 2007; 321 2 526 535 (Pubitemid 46624526)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.321
, Issue.2
, pp. 526-535
-
-
Larosche, I.1
Letteron, P.2
Fromenty, B.3
Vadrot, N.4
Abbey-Toby, A.5
Feldmann, G.6
Pessayre, D.7
Mansouri, A.8
-
50
-
-
21744460524
-
Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis
-
DOI 10.1096/fj.04-3196com
-
Lelliott C. J., López M., Curtis R. K., et al. Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis. FASEB J: 2005; 19 9 1108 1119 (Pubitemid 40946436)
-
(2005)
FASEB Journal
, vol.19
, Issue.9
, pp. 1108-1119
-
-
Lelliott, C.J.1
Lopez, M.2
Curtis, R.K.3
Parker, N.4
Laudes, M.5
Yeo, G.6
Jimenez-Linan, M.7
Grosse, J.8
Saha, A.K.9
Wiggins, D.10
Hauton, D.11
Brand, M.D.12
O'Rahilly, S.13
Griffin, J.L.14
Gibbons, G.F.15
Vidal-Puig, A.16
-
51
-
-
29144466581
-
CYP17 polymorphism and tamoxifen-induced hepatic steatosis
-
DOI 10.1016/j.hepres.2005.09.030, PII S1386634605003177
-
Ohnishi T., Ogawa Y., Saibara T., et al. CYP17 polymorphism and tamoxifen-induced hepatic steatosis. Hepatol Res: 2005; 33 2 178 180 (Pubitemid 41799800)
-
(2005)
Hepatology Research
, vol.33
, Issue.2
, pp. 178-180
-
-
Ohnishi, T.1
Ogawa, Y.2
Saibara, T.3
Nishioka, A.4
Kariya, S.5
Fukumoto, M.6
Onishi, S.7
Yoshida, S.8
-
52
-
-
45749109394
-
Psoriatic arthritis, methotrexate and the liver - Are rheumatologists putting their patients at risk?
-
DOI 10.1093/rheumatology/ken158
-
Lindsay K., Gough A. Psoriatic arthritis, methotrexate and the liver-are rheumatologists putting their patients at risk? Rheumatology (Oxford): 2008; 47 7 939 941 (Pubitemid 351865911)
-
(2008)
Rheumatology
, vol.47
, Issue.7
, pp. 939-941
-
-
Lindsay, K.1
Gough, A.2
-
53
-
-
0035698162
-
Role of non-alcoholic steatohepatitis in methotrexate-induced liver injury
-
DOI 10.1046/j.1440-1746.2001.02644.x
-
Langman G., Hall P. M., Todd G. Role of non-alcoholic steatohepatitis in methotrexate-induced liver injury. J Gastroenterol Hepatol: 2001; 16 12 1395 1401 (Pubitemid 34107409)
-
(2001)
Journal of Gastroenterology and Hepatology
, vol.16
, Issue.12
, pp. 1395-1401
-
-
Langman, G.1
Hall, P.D.L.M.2
Todd, G.3
-
54
-
-
1542359496
-
Monitoring methotrexate-induced hepatic fibrosis in patients with psoriasis: Are serial liver biopsies justified?
-
DOI 10.1046/j.1365-2036.2004.01819.x
-
Aithal G. P., Haugk B., Das S., Card T., Burt A. D., Record C. O. Monitoring methotrexate-induced hepatic fibrosis in patients with psoriasis: are serial liver biopsies justified? Aliment Pharmacol Ther: 2004; 19 4 391 399 (Pubitemid 38297107)
-
(2004)
Alimentary Pharmacology and Therapeutics
, vol.19
, Issue.4
, pp. 391-399
-
-
Aithal, G.P.1
Haugk, B.2
Das, S.3
Card, T.4
Burt, A.D.5
Record, C.O.6
-
55
-
-
2142714501
-
Valproate Therapy and Nonalcoholic Fatty Liver Disease
-
DOI 10.1002/ana.20074
-
Luef G. J., Waldmann M., Sturm W., et al. Valproate therapy and nonalcoholic fatty liver disease. Ann Neurol: 2004; 55 5 729 732 (Pubitemid 38544334)
-
(2004)
Annals of Neurology
, vol.55
, Issue.5
, pp. 729-732
-
-
Luef, G.J.1
Waldmann, M.2
Sturm, W.3
Naser, A.4
Trinka, E.5
Unterberger, I.6
Bauer, G.7
Lechleitner, M.8
-
56
-
-
68749098182
-
Non-alcoholic fatty liver disease (NAFLD), insulin resistance and lipid profile in antiepileptic drug treatment
-
Luef G., Rauchenzauner M., Waldmann M., et al. Non-alcoholic fatty liver disease (NAFLD), insulin resistance and lipid profile in antiepileptic drug treatment. Epilepsy Res: 2009; 86 1 42 47
-
(2009)
Epilepsy Res
, vol.86
, Issue.1
, pp. 42-47
-
-
Luef, G.1
Rauchenzauner, M.2
Waldmann, M.3
-
57
-
-
0024256069
-
Clinical pharmacokinetics of valproic acid-1988
-
Zaccara G., Messori A., Moroni F. Clinical pharmacokinetics of valproic acid-1988. Clin Pharmacokinet: 1988; 15 6 367 389
-
(1988)
Clin Pharmacokinet
, vol.15
, Issue.6
, pp. 367-389
-
-
Zaccara, G.1
Messori, A.2
Moroni, F.3
-
58
-
-
38749126396
-
Toxicity of valproic acid in mice with decreased plasma and tissue carnitine stores
-
DOI 10.1124/jpet.107.131185
-
Knapp A. C., Todesco L., Beier K., et al. Toxicity of valproic acid in mice with decreased plasma and tissue carnitine stores. J Pharmacol Exp Ther: 2008; 324 2 568 575 (Pubitemid 351185875)
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.324
, Issue.2
, pp. 568-575
-
-
Knapp, A.C.1
Todesco, L.2
Beier, K.3
Terracciano, L.4
Sagesser, H.5
Reichen, J.6
Krahenbuhl, S.7
-
59
-
-
72149113307
-
Inhibition of hepatic carnitine palmitoyl-transferase i (CPT IA) by valproyl-CoA as a possible mechanism of valproate-induced steatosis
-
Aires C. C., Ijlst L., Stet F., et al. Inhibition of hepatic carnitine palmitoyl-transferase I (CPT IA) by valproyl-CoA as a possible mechanism of valproate-induced steatosis. Biochem Pharmacol: 2010; 79 5 792 799
-
(2010)
Biochem Pharmacol
, vol.79
, Issue.5
, pp. 792-799
-
-
Aires, C.C.1
Ijlst, L.2
Stet, F.3
-
60
-
-
33846151732
-
Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia
-
DOI 10.1056/NEJMoa061189
-
Cuchel M., Bloedon L. T., Szapary P. O., et al. Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia. N Engl J Med: 2007; 356 2 148 156 (Pubitemid 46089675)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 148-156
-
-
Cuchel, M.1
Bloedon, L.T.2
Szapary, P.O.3
Kolansky, D.M.4
Wolfe, M.L.5
Sarkis, A.6
Millar, J.S.7
Ikewaki, K.8
Siegelman, E.S.9
Gregg, R.E.10
Rader, D.J.11
-
61
-
-
84875406000
-
Mipomersen and other therapies for the treatment of severe familial hypercholesterolemia
-
Bell D. A., Hooper A. J., Watts G. F., Burnett J. R. Mipomersen and other therapies for the treatment of severe familial hypercholesterolemia. Vasc Health Risk Manag: 2012; 8 651 659
-
(2012)
Vasc Health Risk Manag
, vol.8
, pp. 651-659
-
-
Bell, D.A.1
Hooper, A.J.2
Watts, G.F.3
Burnett, J.R.4
-
62
-
-
84864239186
-
Therapeutic potential of mipomersen in the management of familial hypercholesterolaemia
-
Gelsinger C., Steinhagen-Thiessen E., Kassner U. Therapeutic potential of mipomersen in the management of familial hypercholesterolaemia. Drugs: 2012; 72 11 1445 1455
-
(2012)
Drugs
, vol.72
, Issue.11
, pp. 1445-1455
-
-
Gelsinger, C.1
Steinhagen-Thiessen, E.2
Kassner, U.3
-
63
-
-
84869039132
-
Randomized, placebo-controlled trial of mipomersen in patients with severe hypercholesterolemia receiving maximally tolerated lipid-lowering therapy
-
McGowan M. P., Tardif J. C., Ceska R., et al. Randomized, placebo-controlled trial of mipomersen in patients with severe hypercholesterolemia receiving maximally tolerated lipid-lowering therapy. PLoS ONE: 2012; 7 11 e49006
-
(2012)
PLoS ONE
, vol.7
, Issue.11
-
-
McGowan, M.P.1
Tardif, J.C.2
Ceska, R.3
-
64
-
-
84860615159
-
Mipomersen, an apolipoprotein B synthesis inhibitor, lowers low-density lipoprotein cholesterol in high-risk statin-intolerant patients: A randomized, double-blind, placebo-controlled trial
-
Visser M. E., Wagener G., Baker B. F., et al. Mipomersen, an apolipoprotein B synthesis inhibitor, lowers low-density lipoprotein cholesterol in high-risk statin-intolerant patients: a randomized, double-blind, placebo-controlled trial. Eur Heart J: 2012; 33 9 1142 1149
-
(2012)
Eur Heart J
, vol.33
, Issue.9
, pp. 1142-1149
-
-
Visser, M.E.1
Wagener, G.2
Baker, B.F.3
-
65
-
-
84882927131
-
New LDL-cholesterol lowering therapies: Pharmacology, clinical trials, and relevance to acute coronary syndromes
-
Sahebkar A., Watts G. F. New LDL-cholesterol lowering therapies: pharmacology, clinical trials, and relevance to acute coronary syndromes. Clin Ther: 2013; 35 8 1082 1098
-
(2013)
Clin Ther
, vol.35
, Issue.8
, pp. 1082-1098
-
-
Sahebkar, A.1
Watts, G.F.2
-
66
-
-
84871945617
-
Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: A single-arm, open-label, phase 3 study
-
Phase 3 HoFH Lomitapide Study investigators.
-
Cuchel M., Meagher E. A., du Toit Theron H., et al. Phase 3 HoFH Lomitapide Study investigators. Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study. Lancet: 2013; 381 9860 40 46
-
(2013)
Lancet
, vol.381
, Issue.9860
, pp. 40-46
-
-
Cuchel, M.1
Meagher, E.A.2
Du Toit Theron, H.3
-
67
-
-
1642578228
-
Adverse effects of antiretroviral therapy for HIV infection
-
Montessori V., Press N., Harris M., Akagi L., Montaner J. S. Adverse effects of antiretroviral therapy for HIV infection. CMAJ: 2004; 170 2 229 238 (Pubitemid 38134804)
-
(2004)
Canadian Medical Association Journal
, vol.170
, Issue.2
, pp. 229-238
-
-
Montessori, V.1
Press, N.2
Harris, M.3
Akagi, L.4
Montaner, J.S.G.5
-
68
-
-
17444409275
-
Hepatic steatosis and antiretroviral drug use among adults coinfected with HIV and hepatitis C virus
-
Sulkowski M. S., Mehta S. H., Torbenson M., et al. Hepatic steatosis and antiretroviral drug use among adults coinfected with HIV and hepatitis C virus. AIDS: 2005; 19 6 585 592 (Pubitemid 40543981)
-
(2005)
AIDS
, vol.19
, Issue.6
, pp. 585-592
-
-
Sulkowski, M.S.1
Mehta, S.H.2
Torbenson, M.3
Afdhal, N.H.4
Mirel, L.5
Moore, R.D.6
Thomas, D.L.7
-
69
-
-
0032897185
-
Zidovudine-induced mitochondrial disorder with massive liver steatosis, myopathy, lactic acidosis, and mitochondrial DNA depletion
-
DOI 10.1016/S0168-8278(99)80020-8
-
Chariot P., Drogou I., de Lacroix-Szmania I., et al. Zidovudine-induced mitochondrial disorder with massive liver steatosis, myopathy, lactic acidosis, and mitochondrial DNA depletion. J Hepatol: 1999; 30 1 156 160 (Pubitemid 29023665)
-
(1999)
Journal of Hepatology
, vol.30
, Issue.1
, pp. 156-160
-
-
Chariot, P.1
Drogou, I.2
Lacroix-Szmania, I.D.3
Eliezer-Vanerot, M.-C.4
Chazaud, B.5
Lombes, A.6
Schaeffer, A.7
Zafrani, E.S.8
-
70
-
-
84885397513
-
Zidovudine (AZT) and hepatic lipid accumulation: Implication of inflammation, oxidative and endoplasmic reticulum stress mediators
-
Banerjee A., Abdelmegeed M. A., Jang S., Song B. J. Zidovudine (AZT) and hepatic lipid accumulation: implication of inflammation, oxidative and endoplasmic reticulum stress mediators. PLoS ONE: 2013; 8 10 e76850
-
(2013)
PLoS ONE
, vol.8
, Issue.10
-
-
Banerjee, A.1
Abdelmegeed, M.A.2
Jang, S.3
Song, B.J.4
-
71
-
-
34247373546
-
Hepatic steatosis has no impact on the outcome of treatment in patients with chronic hepatitis B infection
-
DOI 10.1097/01.mcg.0000225586.78330.60, PII 0000483620070500000016
-
Cindoruk M., Karakan T., Unal S. Hepatic steatosis has no impact on the outcome of treatment in patients with chronic hepatitis B infection. J Clin Gastroenterol: 2007; 41 5 513 517 (Pubitemid 46642541)
-
(2007)
Journal of Clinical Gastroenterology
, vol.41
, Issue.5
, pp. 513-517
-
-
Cindoruk, M.1
Karakan, T.2
Unal, S.3
-
72
-
-
33645421568
-
Hepatic steatosis in HIV-HCV coinfected patients: Analysis of risk factors
-
DOI 10.1097/01.aids.0000210606.63138.f5, PII 0000203020060228000005
-
Bani-Sadr F., Carrat F., Bedossa P., et al. ANRS HC02 - Ribavic Study team. Hepatic steatosis in HIV-HCV coinfected patients: analysis of risk factors. AIDS: 2006; 20 4 525 531 (Pubitemid 43731596)
-
(2006)
AIDS
, vol.20
, Issue.4
, pp. 525-531
-
-
Bani-Sadr, F.1
Carrat, F.2
Bedossa, P.3
Piroth, L.4
Cacoub, P.5
Perronne, C.6
Degott, C.7
Pol, S.8
-
73
-
-
84879506210
-
Absence of liver steatosis in HIV-HCV co-infected patients receiving regimens containing tenofovir or abacavir
-
Borghi V., Bisi L., Manzini L., Cossarizza A., Mussini C. Absence of liver steatosis in HIV-HCV co-infected patients receiving regimens containing tenofovir or abacavir. Infection: 2013; 41 2 425 429
-
(2013)
Infection
, vol.41
, Issue.2
, pp. 425-429
-
-
Borghi, V.1
Bisi, L.2
Manzini, L.3
Cossarizza, A.4
Mussini, C.5
-
74
-
-
84862169241
-
Hepatic steatosis in HIV-HCV coinfected patients receiving antiretroviral therapy is associated with HCV-related factors but not antiretrovirals
-
Martinez V., Ta T. D., Mokhtari Z., et al. Hepatic steatosis in HIV-HCV coinfected patients receiving antiretroviral therapy is associated with HCV-related factors but not antiretrovirals. BMC Res Notes: 2012; 5 180
-
(2012)
BMC Res Notes
, vol.5
, pp. 180
-
-
Martinez, V.1
Ta, T.D.2
Mokhtari, Z.3
-
75
-
-
20344398892
-
Effects of oral 5-fluorouracil drugs on hepatic fat content in patients with colon cancer
-
DOI 10.1016/j.acra.2005.02.010, PII S1076633205001182
-
Miyake K., Hayakawa K., Nishino M., Morimoto T., Mukaihara S. Effects of oral 5-fluorouracil drugs on hepatic fat content in patients with colon cancer. Acad Radiol: 2005; 12 6 722 727 (Pubitemid 40791088)
-
(2005)
Academic Radiology
, vol.12
, Issue.6
, pp. 722-727
-
-
Miyake, K.1
Hayakawa, K.2
Nishino, M.3
Morimoto, T.4
Mukaihara, S.5
-
76
-
-
33750957147
-
Liver histology and surgical outcomes after preoperative chemotherapy with fluorouracil plus oxaliplatin in colorectal cancer liver metastases
-
DOI 10.1200/JCO.2006.05.8156
-
Aloia T., Sebagh M., Plasse M., et al. Liver histology and surgical outcomes after preoperative chemotherapy with fluorouracil plus oxaliplatin in colorectal cancer liver metastases. J Clin Oncol: 2006; 24 31 4983 4990 (Pubitemid 46631400)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.31
, pp. 4983-4990
-
-
Aloia, T.1
Sebagh, M.2
Plasse, M.3
Karam, V.4
Levi, F.5
Giacchetti, S.6
Azoulay, D.7
Bismuth, H.8
Castaing, D.9
Adam, R.10
-
77
-
-
84871241124
-
Preoperative chemotherapy and the risk of hepatotoxicity and morbidity after liver resection for metastatic colorectal cancer: A single institution experience
-
Wolf P. S., Park J. O., Bao F., et al. Preoperative chemotherapy and the risk of hepatotoxicity and morbidity after liver resection for metastatic colorectal cancer: a single institution experience. J Am Coll Surg: 2013; 216 1 41 49
-
(2013)
J Am Coll Surg
, vol.216
, Issue.1
, pp. 41-49
-
-
Wolf, P.S.1
Park, J.O.2
Bao, F.3
-
78
-
-
84859702946
-
Correlations between histopathological diagnosis of chemotherapy-induced hepatic injury, clinical features, and perioperative morbidity
-
Pilgrim C. H., Satgunaseelan L., Pham A., et al. Correlations between histopathological diagnosis of chemotherapy-induced hepatic injury, clinical features, and perioperative morbidity. HPB (Oxford): 2012; 14 5 333 340
-
(2012)
HPB (Oxford)
, vol.14
, Issue.5
, pp. 333-340
-
-
Pilgrim, C.H.1
Satgunaseelan, L.2
Pham, A.3
-
79
-
-
33745283424
-
Non alcoholic fatty liver disease: A clinical approach and review
-
Raman M., Allard J. Non alcoholic fatty liver disease: a clinical approach and review. Can J Gastroenterol: 2006; 20 5 345 349
-
(2006)
Can J Gastroenterol
, vol.20
, Issue.5
, pp. 345-349
-
-
Raman, M.1
Allard, J.2
-
80
-
-
79957474305
-
Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in HepaRG cells
-
Anthérieu S., Rogue A., Fromenty B., Guillouzo A., Robin M. A. Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in HepaRG cells. Hepatology: 2011; 53 6 1895 1905
-
(2011)
Hepatology
, vol.53
, Issue.6
, pp. 1895-1905
-
-
Anthérieu, S.1
Rogue, A.2
Fromenty, B.3
Guillouzo, A.4
Robin, M.A.5
-
81
-
-
63649142566
-
Patterns of chemotherapy-induced hepatic injury and their implications for patients undergoing liver resection for colorectal liver metastases
-
Khan A. Z., Morris-Stiff G., Makuuchi M. Patterns of chemotherapy-induced hepatic injury and their implications for patients undergoing liver resection for colorectal liver metastases. J Hepatobiliary Pancreat Surg: 2009; 16 2 137 144
-
(2009)
J Hepatobiliary Pancreat Surg
, vol.16
, Issue.2
, pp. 137-144
-
-
Khan, A.Z.1
Morris-Stiff, G.2
Makuuchi, M.3
-
82
-
-
84901808704
-
Liver injury induced by anticancer chemotherapy and radiation therapy
-
2013: Article ID 815105
-
Maor Y., Malnick S. Liver injury induced by anticancer chemotherapy and radiation therapy. Int J Hepatol: 2013;: 2013;: Article ID 815105
-
(2013)
Int J Hepatol
-
-
Maor, Y.1
Malnick, S.2
-
83
-
-
67649221506
-
Histological patterns in drug-induced liver disease
-
Ramachandran R., Kakar S. Histological patterns in drug-induced liver disease. J Clin Pathol: 2009; 62 6 481 492
-
(2009)
J Clin Pathol
, vol.62
, Issue.6
, pp. 481-492
-
-
Ramachandran, R.1
Kakar, S.2
|