메뉴 건너뛰기




Volumn 9, Issue 6, 2014, Pages 798-802

Reprogramming cancer cells to pluripotency: An experimental tool for exploring cancer epigenetics

Author keywords

Cancer; DNA methylation; Epigenetics; Glioblastoma; iPS cells; Neural stem cell; Polycomb; Reprogramming

Indexed keywords

ARTICLE; CANCER CELL; CARCINOGENICITY; DNA METHYLATION; DNA MODIFICATION; DNA REPLICATION; EPIGENETICS; GENE EXPRESSION; GENE SILENCING; GLIOBLASTOMA; HUMAN; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; STEM CELL TRANSPLANTATION; ANIMAL; BRAIN TUMOR; CANCER STEM CELL; CARCINOGENESIS; CELL LINEAGE; GENETIC EPIGENESIS; GENETICS; INDUCED PLURIPOTENT STEM CELL; METABOLISM; NEURAL STEM CELL; PATHOLOGY; TUMOR CELL LINE;

EID: 84901745408     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.28600     Document Type: Article
Times cited : (14)

References (49)
  • 1
    • 84863621527 scopus 로고    scopus 로고
    • Cancer epigenetics: From mechanism to therapy
    • PMID:22770212
    • Dawson MA, Kouzarides T. Cancer epigenetics: from mechanism to therapy. Cell 2012; 150:12-27; PMID:22770212; http://dx.doi.org/10.1016/j. cell.2012.06.013
    • (2012) Cell , vol.150 , pp. 12-27
    • Dawson, M.A.1    Kouzarides, T.2
  • 3
    • 76249133692 scopus 로고    scopus 로고
    • Defined factors induce reprogramming of gastrointestinal cancer cells
    • ed. 2010 Jan 5
    • Miyoshi N, Ishii H, Nagai K, Hoshino H, Mimori K, Tanaka F, et al. Defined factors induce reprogramming of gastrointestinal cancer cells. Proc Natl Acad Sci USA. 2009 ed. 2010 Jan 5;107(1):40-5.
    • (2009) Proc Natl Acad Sci USA. , vol.107 , Issue.1 , pp. 40-45
    • Miyoshi, N.1    Ishii, H.2    Nagai, K.3    Hoshino, H.4    Mimori, K.5    Tanaka, F.6
  • 4
    • 84875340771 scopus 로고    scopus 로고
    • Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner
    • PMID:23512659
    • Stricker SH, Feber A, Engström PG, Carén H, Kurian KM, Takashima Y, Watts C, Way M, Dirks P, Bertone P, et al. Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner. Genes Dev 2013; 27:654-69; PMID:23512659; http://dx.doi.org/10.1101/gad.212662.112
    • (2013) Genes Dev , vol.27 , pp. 654-669
    • Stricker, S.H.1    Feber, A.2    Engström, P.G.3    Carén, H.4    Kurian, K.M.5    Takashima, Y.6    Watts, C.7    Way, M.8    Dirks, P.9    Bertone, P.10
  • 5
    • 84882281368 scopus 로고    scopus 로고
    • Generation of iPS cells from normal and malignant hematopoietic cells
    • Kumano K, Arai S, Kurokawa M. Generation of iPS cells from normal and malignant hematopoietic cells. Int J Hematol. Springer Japan 2013; 98:145-52
    • (2013) Int J Hematol. Springer Japan , vol.98 , pp. 145-152
    • Kumano, K.1    Arai, S.2    Kurokawa, M.3
  • 6
    • 84879798872 scopus 로고    scopus 로고
    • An iPSC line from human pancreatic ductal adenocarcinoma undergoes early to invasive stages of pancreatic cancer progression
    • PMID:23791528
    • Kim J, Hoffman JP, Alpaugh RK, Rhim AD, Reichert M, Stanger BZ, Furth EE, Sepulveda AR, Yuan CX, Won KJ, et al. An iPSC line from human pancreatic ductal adenocarcinoma undergoes early to invasive stages of pancreatic cancer progression. Cell Rep 2013; 3:2088-99; PMID:23791528; http://dx.doi. org/10.1016/j.celrep.2013.05.036
    • (2013) Cell Rep , vol.3 , pp. 2088-2099
    • Kim, J.1    Hoffman, J.P.2    Alpaugh, R.K.3    Rhim, A.D.4    Reichert, M.5    Stanger, B.Z.6    Furth, E.E.7    Sepulveda, A.R.8    Yuan, C.X.9    Won, K.J.10
  • 8
    • 0020699979 scopus 로고
    • Hypomethylation distinguishes genes of some human cancers from their normal counterparts
    • PMID:6185846
    • Feinberg AP, Vogelstein B. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 1983; 301:89-92; PMID:6185846; http://dx.doi. org/10.1038/301089a0
    • (1983) Nature , vol.301 , pp. 89-92
    • Feinberg, A.P.1    Vogelstein, B.2
  • 9
    • 1042278765 scopus 로고    scopus 로고
    • The history of cancer epigenetics
    • PMID:14732866
    • Feinberg AP, Tycko B. The history of cancer epigenetics. Nat Rev Cancer 2004; 4:143-53; PMID:14732866; http://dx.doi.org/10.1038/ nrc1279
    • (2004) Nat Rev Cancer , vol.4 , pp. 143-153
    • Feinberg, A.P.1    Tycko, B.2
  • 10
    • 80755187797 scopus 로고    scopus 로고
    • Genomic imprinting: A mammalian epigenetic discovery model
    • PMID:21942369
    • Barlow DP. Genomic imprinting: a mammalian epigenetic discovery model. Annu Rev Genet 2011; 45:379-403; PMID:21942369; http://dx.doi. org/10.1146/annurev-genet-110410-132459
    • (2011) Annu Rev Genet , vol.45 , pp. 379-403
    • Barlow, D.P.1
  • 12
    • 0032901199 scopus 로고    scopus 로고
    • Cytosine methylation and mammalian development
    • PMID:9887097
    • Walsh CP, Bestor TH. Cytosine methylation and mammalian development. Genes Dev 1999; 13:26-34; PMID:9887097; http://dx.doi.org/10.1101/ gad.13.1.26
    • (1999) Genes Dev , vol.13 , pp. 26-34
    • Walsh, C.P.1    Bestor, T.H.2
  • 13
    • 36849004469 scopus 로고    scopus 로고
    • Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing
    • PMID:18056424
    • Linhart HG, Lin H, Yamada Y, Moran E, Steine EJ, Gokhale S, Lo G, Cantu E, Ehrich M, He T, et al. Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing. Genes Dev 2007; 21:3110-22; PMID:18056424; http://dx.doi.org/10.1101/gad.1594007
    • (2007) Genes Dev , vol.21 , pp. 3110-3122
    • Linhart, H.G.1    Lin, H.2    Yamada, Y.3    Moran, E.4    Steine, E.J.5    Gokhale, S.6    Lo, G.7    Cantu, E.8    Ehrich, M.9    He, T.10
  • 15
    • 42649089780 scopus 로고    scopus 로고
    • The methylome: Approaches for global DNA methylation profiling
    • PMID:18325624
    • Beck S, Rakyan VK. The methylome: approaches for global DNA methylation profiling. Trends Genet 2008; 24:231-7; PMID:18325624; http://dx.doi. org/10.1016/j.tig.2008.01.006
    • (2008) Trends Genet , vol.24 , pp. 231-237
    • Beck, S.1    Rakyan, V.K.2
  • 16
    • 77249137168 scopus 로고    scopus 로고
    • Principles and challenges of genome-wide DNA methylation analysis
    • Laird PW. Principles and challenges of genome-wide DNA methylation analysis. Nat Rev Genet. 2010; 11:191-203
    • (2010) Nat Rev Genet. , vol.11 , pp. 191-203
    • Laird, P.W.1
  • 17
    • 77957970498 scopus 로고    scopus 로고
    • Epigenetic modifications in pluripotent and differentiated cells
    • PMID:20944600
    • Meissner A. Epigenetic modifications in pluripotent and differentiated cells. Nat Biotechnol 2010; 28:1079-88; PMID:20944600; http://dx.doi. org/10.1038/nbt.1684
    • (2010) Nat Biotechnol , vol.28 , pp. 1079-1088
    • Meissner, A.1
  • 19
    • 0037355506 scopus 로고    scopus 로고
    • Unanswered questions about the role of promoter methylation in carcinogenesis
    • PMID:12724209
    • Bestor TH. Unanswered questions about the role of promoter methylation in carcinogenesis. Ann N Y Acad Sci 2003; 983:22-7; PMID:12724209; http:// dx.doi.org/10.1111/j.1749-6632.2003.tb05959.x
    • (2003) Ann N Y Acad Sci , vol.983 , pp. 22-27
    • Bestor, T.H.1
  • 20
    • 33846569960 scopus 로고    scopus 로고
    • A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
    • PMID:17211412
    • Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, Mohammad HP, Chen W, Daniel VC, Yu W, et al. A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet 2007; 39:237-42; PMID:17211412; http://dx.doi. org/10.1038/ng1972
    • (2007) Nat Genet , vol.39 , pp. 237-242
    • Ohm, J.E.1    McGarvey, K.M.2    Yu, X.3    Cheng, L.4    Schuebel, K.E.5    Cope, L.6    Mohammad, H.P.7    Chen, W.8    Daniel, V.C.9    Yu, W.10
  • 22
    • 29244469466 scopus 로고    scopus 로고
    • The epigenetic progenitor origin of human cancer
    • PMID:16369569
    • Feinberg AP, Ohlsson R, Henikoff S. The epigenetic progenitor origin of human cancer. Nat Rev Genet 2006; 7:21-33; PMID:16369569; http://dx.doi. org/10.1038/nrg1748
    • (2006) Nat Rev Genet , vol.7 , pp. 21-33
    • Feinberg, A.P.1    Ohlsson, R.2    Henikoff, S.3
  • 23
    • 84881086323 scopus 로고    scopus 로고
    • Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host
    • PMID:23760024
    • Timp W, Feinberg AP. Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host. Nat Rev Cancer 2013; 13:497-510; PMID:23760024; http://dx.doi.org/10.1038/ nrc3486
    • (2013) Nat Rev Cancer , vol.13 , pp. 497-510
    • Timp, W.1    Feinberg, A.P.2
  • 24
    • 84875745673 scopus 로고    scopus 로고
    • Interplay between the cancer genome and epigenome
    • PMID:23540689
    • Shen H, Laird PW. Interplay between the cancer genome and epigenome. Cell 2013; 153:38-55; PMID:23540689; http://dx.doi.org/10.1016/j. cell.2013.03.008
    • (2013) Cell , vol.153 , pp. 38-55
    • Shen, H.1    Laird, P.W.2
  • 25
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • PMID:21376230
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144:646-74; PMID:21376230; http://dx.doi.org/10.1016/j. cell.2011.02.013
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 27
    • 77953466536 scopus 로고    scopus 로고
    • Nuclear reprogramming to a pluripotent state by three approaches
    • PMID:20535199
    • Yamanaka S, Blau HM. Nuclear reprogramming to a pluripotent state by three approaches. Nature 2010; 465:704-12; PMID:20535199; http://dx.doi. org/10.1038/nature09229
    • (2010) Nature , vol.465 , pp. 704-712
    • Yamanaka, S.1    Blau, H.M.2
  • 28
    • 64249157351 scopus 로고    scopus 로고
    • Epigenetic reprogramming and induced pluripotency
    • PMID:19168672
    • Hochedlinger K, Plath K. Epigenetic reprogramming and induced pluripotency. Development 2009; 136:509-23; PMID:19168672; http://dx.doi. org/10.1242/dev.020867
    • (2009) Development , vol.136 , pp. 509-523
    • Hochedlinger, K.1    Plath, K.2
  • 30
    • 33646358694 scopus 로고    scopus 로고
    • Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
    • PMID:16697959
    • Lee J, Kotliarova S, Kotliarov Y, Li A, Su Q, Donin NM, Pastorino S, Purow BW, Christopher N, Zhang W, et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 2006; 9:391-403; PMID:16697959; http://dx.doi.org/10.1016/j. ccr.2006.03.030
    • (2006) Cancer Cell , vol.9 , pp. 391-403
    • Lee, J.1    Kotliarova, S.2    Kotliarov, Y.3    Li, A.4    Su, Q.5    Donin, N.M.6    Pastorino, S.7    Purow, B.W.8    Christopher, N.9    Zhang, W.10
  • 31
    • 66049085403 scopus 로고    scopus 로고
    • Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens
    • PMID:19497285
    • Pollard SM, Yoshikawa K, Clarke ID, Danovi D, Stricker S, Russell R, Bayani J, Head R, Lee M, Bernstein M, et al. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. Cell Stem Cell 2009; 4:568-80; PMID:19497285; http:// dx.doi.org/10.1016/j.stem.2009.03.014
    • (2009) Cell Stem Cell , vol.4 , pp. 568-580
    • Pollard, S.M.1    Yoshikawa, K.2    Clarke, I.D.3    Danovi, D.4    Stricker, S.5    Russell, R.6    Bayani, J.7    Head, R.8    Lee, M.9    Bernstein, M.10
  • 32
    • 84867125364 scopus 로고    scopus 로고
    • Digital transcriptome profiling of normal and glioblastoma-derived neural stem cells identifies genes associated with patient survival
    • PMID:23046790
    • Engström PG, Tommei D, Stricker SH, Ender C, Pollard SM, Bertone P. Digital transcriptome profiling of normal and glioblastoma-derived neural stem cells identifies genes associated with patient survival. Genome Med 2012; 4:76; PMID:23046790; http:// dx.doi.org/10.1186/gm377
    • (2012) Genome Med , vol.4 , pp. 76
    • Engström, P.G.1    Tommei, D.2    Stricker, S.H.3    Ender, C.4    Pollard, S.M.5    Bertone, P.6
  • 39
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev A, et al. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 2008; 40:499-507.
    • (2008) Nat Genet , vol.40 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3    Ge, R.4    Bell, G.W.5    Regev, A.6
  • 40
    • 77957757417 scopus 로고    scopus 로고
    • A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs
    • Kim J, Woo AJ, Chu J, Snow JW, Fujiwara Y, Kim CG, et al. A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs. Cell 2010; 143:313-24.
    • (2010) Cell , vol.143 , pp. 313-324
    • Kim, J.1    Woo, A.J.2    Chu, J.3    Snow, J.W.4    Fujiwara, Y.5    Kim, C.G.6
  • 41
    • 33645751058 scopus 로고    scopus 로고
    • Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state
    • PMID:16585178
    • McGarvey KM, Fahrner JA, Greene E, Martens J, Jenuwein T, Baylin SB. Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state. Cancer Res 2006; 66:3541-9; PMID:16585178; http:// dx.doi.org/10.1158/0008-5472.CAN-05-2481
    • (2006) Cancer Res , vol.66 , pp. 3541-3549
    • McGarvey, K.M.1    Fahrner, J.A.2    Greene, E.3    Martens, J.4    Jenuwein, T.5    Baylin, S.B.6
  • 42
    • 79952716583 scopus 로고    scopus 로고
    • Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer
    • PMID:21368160
    • Sproul D, Nestor C, Culley J, Dickson JH, Dixon JM, Harrison DJ, Meehan RR, Sims AH, Ramsahoye BH. Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer. Proc Natl Acad Sci U S A 2011; 108:4364-9; PMID:21368160; http://dx.doi. org/10.1073/pnas.1013224108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 4364-4369
    • Sproul, D.1    Nestor, C.2    Culley, J.3    Dickson, J.H.4    Dixon, J.M.5    Harrison, D.J.6    Meehan, R.R.7    Sims, A.H.8    Ramsahoye, B.H.9
  • 45
    • 84862777410 scopus 로고    scopus 로고
    • St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
    • PMID:22286216
    • Wu G, Broniscer A, McEachron TA, Lu C, Paugh BS, Becksfort J, Qu C, Ding L, Huether R, Parker M, et al.; St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat Genet 2012; 44:251-3; PMID:22286216; http://dx.doi.org/10.1038/ ng.1102
    • (2012) Nat Genet , vol.44 , pp. 251-253
    • Wu, G.1    Broniscer, A.2    McEachron, T.A.3    Lu, C.4    Paugh, B.S.5    Becksfort, J.6    Qu, C.7    Ding, L.8    Huether, R.9    Parker, M.10
  • 47
    • 70350500219 scopus 로고    scopus 로고
    • Polycomb group proteins: Navigators of lineage pathways led astray in cancer
    • PMID:19851313
    • Bracken AP, Helin K. Polycomb group proteins: navigators of lineage pathways led astray in cancer. Nat Rev Cancer 2009; 9:773-84; PMID:19851313; http:// dx.doi.org/10.1038/nrc2736.
    • (2009) Nat Rev Cancer , vol.9 , pp. 773-784
    • Bracken, A.P.1    Helin, K.2
  • 48


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.