Application of thermoresponsive PNIPAAM-b-PAMPTMA diblock copolymers in siRNA delivery

Molecular Pharmaceutics

Volumn 11, Issue 3, 2014, Pages 819-827

  Cardoso, Ana M ^a,b   Calejo, M Teresa ^c   Morais, Catarina M ^a,b   Cardoso, Ana L ^a   Cruz, Rita ^b   Zhu, Kaizheng ^d   Pedroso De Lima, Maria C ^a,b   Jurado, Amália S ^a,b   Nyström, Bo ^d  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^d UNIVERSITY OF OSLO   (Norway)

Author keywords

cancer gene therapy; cloud point; nonviral vector; polyplex; siRNA delivery; thermoresponsive copolymer

Indexed keywords

COPOLYMER; NUCLEIC ACID; POLY(N ISOPROPYLACRYLAMIDE)N BLOCK POLY[(3 ACRYLAMIDOPROPYL)TRIMETHYLAMMONIUM CHLORIDE]M; POLYMER; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CETUXIMAB; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR; LUTETIUM; MONOCLONAL ANTIBODY; PANITUMUMAB;

ARTICLE; CANCER CELL CULTURE; CONFOCAL FLUORESCENCE; CONTROLLED STUDY; CYTOTOXICITY; DISSOCIATION; FIBROSARCOMA CELL LINE; FLUORESCENCE; GENE DELIVERY SYSTEM; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; INTERNALIZATION; PRECIPITATION; PRIORITY JOURNAL; SERUM; SOLUBILIZATION; TRANSITION TEMPERATURE; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; DRUG EFFECTS; DRUG SCREENING; FEMALE; HEAD AND NECK NEOPLASMS; IMMUNOLOGY; METABOLISM; MOUSE; RADIATION RESPONSE; RADIOIMMUNOTHERAPY; SCINTISCANNING; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TISSUE DISTRIBUTION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; LUTETIUM; MICE; MICE, INBRED BALB C; RADIOIMMUNOTHERAPY; RECEPTOR, EPIDERMAL GROWTH FACTOR; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84901742907     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400510a     Document Type: Article

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