Canine Hereditary Ataxia in Old English Sheepdogs and Gordon Setters Is Associated with a Defect in the Autophagy Gene Encoding RAB24

PLoS Genetics

Volumn 10, Issue 2, 2014, Pages

  Agler, Caryline ^a   Nielsen, Dahlia M ^a   Urkasemsin, Ganokon ^a   Singleton, Andrew ^b   Tonomura, Noriko ^c,d   Sigurdsson, Snaevar ^c   Tang, Ruqi ^c   Linder, Keith ^a   Arepalli, Sampath ^b   Hernandez, Dena ^b   Lindblad Toh, Kerstin ^c,e   van de Leemput, Joyce ^b   Motsinger Reif, Alison ^a   O'Brien, Dennis P ^f   Bell, Jerold ^d   Harris, Tonya ^a   Steinberg, Steven ^g   Olby, Natasha J ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d TUFTS UNIVERSITY   (United States)

^e UPPSALA UNIVERSITY   (Sweden)

^f UNIVERSITY OF MISSOURI   (United States)

^g VCA Veterinary Referral Associates   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; CFA4 GENE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE; GENE EXPRESSION REGULATION; GENE LOCATION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; HEREDITARY ATAXIA; HISTOPATHOLOGY; HOMOZYGOSITY; IMMUNOHISTOCHEMISTRY; LINKAGE ANALYSIS; MALE; MUTATIONAL ANALYSIS; NEXT GENERATION SEQUENCING; NONHUMAN; PHENOTYPIC VARIATION; PURKINJE CELL; QUANTITATIVE ANALYSIS; RAB24 GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; SEGREGATION ANALYSIS; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; ANIMAL; AUTOPHAGY; CEREBELLUM CORTEX; CHROMOSOME MAP; DOG; DOG DISEASE; GENETICS; HIGH THROUGHPUT SEQUENCING; HUMAN; MOUSE; MUTATION; PATHOLOGY; SPINOCEREBELLAR DEGENERATIONS;

RAB PROTEIN; RAB24 PROTEIN, HUMAN;

ANIMALS; AUTOPHAGY; CEREBELLAR CORTEX; CHROMOSOME MAPPING; DOG DISEASES; DOGS; GENOME-WIDE ASSOCIATION STUDY; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MICE; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; RAB GTP-BINDING PROTEINS; SPINOCEREBELLAR DEGENERATIONS;

EID: 84901741490     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003991     Document Type: Article

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