Genetic structure of the purebred domestic domestic dog

Science

Volumn 304, Issue 5674, 2004, Pages 1160-1164

  Parker, Heidi G ^a,b   Kim, Lisa V ^a,b   Sutter, Nathan B ^a   Carlson, Scott ^a   Lorentzen, Travis D ^a   Malek, Tiffany B ^a,b   Johnson, Gary S ^c   DeFrance, Hawkins B ^a   Ostrander, Elaine A ^a,b   Kruglyak, Leonid ^a,b,d  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF MISSOURI   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMARKERS; BIOTECHNOLOGY; GENES; LIVING SYSTEMS STUDIES; MUTAGENESIS;

BREEDS; GENOTYPES;

GENETIC ENGINEERING;

MITOCHONDRIAL DNA;

GENETICS;

ARTICLE; BREED; DOG; DOMESTIC ANIMAL; GENETIC VARIABILITY; GENOTYPE; NONHUMAN; PHYLOGENY; POPULATION GENETICS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ALGORITHMS; ANIMALS; BAYES THEOREM; BREEDING; COMPUTATIONAL BIOLOGY; DOG DISEASES; DOGS; EVOLUTION; GENOME; GENOTYPE; MICROSATELLITE REPEATS; PHENOTYPE; PHYLOGENY; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA; SOFTWARE; VARIATION (GENETICS);

ANIMALIA; CANIS FAMILIARIS; CANIS LUPUS; MAMMALIA;

EID: 2442653898     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1097406     Document Type: Article

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31. Supported by the Burroughs Wellcome Innovation Award (E.A.O. and L.K.), grants from the AKC-Canine Health Foundation (G.S.J.), NIH training grant T32 HG00035 (H.G.P.), and a postdoctoral fellowship from the Waltham Foundation (N.B.S.). E.A.0. also acknowledges support from K05 CA90754. L.K. is a James S. HcDonnell Centennial Fellow. We thank the many dog owners, researchers, and breeders who provided DNA samples for this work, especially G. Brewer, C. Gaiser, and K. Murphy; D. Lynch, A. Ziska, C. Ramirez, M. Langiols, and D. Akey for assistance with sample collection; M. Stephens for advice and assistance with the program structure; K. Markianos and J. Akey for helpful discussions: M. Eberle for computing assistance; H. Coller, E. Giniger, R. Wayne, and three anonymous reviewers for comments on the manuscript; and the AKC and C. Jierski for use of the canine artwork included in Fig. 3.