Genome-wide mRNA sequencing of a single canine cerebellar cortical degeneration case leads to the identification of a disease associated SPTBN2 mutation

BMC Genetics

Volumn 13, Issue , 2012, Pages

  Forman, Oliver P ^a   De Risio, Luisa ^a   Stewart, Jennifer ^a   Mellersh, Cathryn S ^a   Beltran, Elsa ^a  

^a ANIMAL HEALTH TRUST   (United Kingdom)

Author keywords

Beagle dogs; Beta III spectrin; Canine; Cerebellar cortical degeneration; Cerebellum; Genome wide mRNA sequencing; MRNA seq; Next generation sequencing; Spinocerebellar ataxia type 5; Sptbn2

Indexed keywords

MESSENGER RNA; RNA; SPECTRIN; SPECTRIN BETA III; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CADAVER; CELL DAMAGE; CELL LOSS; CEREBELLAR ATAXIA; CEREBELLUM CORTEX; CLINICAL FEATURE; EUTHANASIA; EXCITOTOXICITY; EXPERIMENTAL DOG; GENE; GENE DELETION; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC VARIABILITY; GENOTYPE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PURKINJE CELL; SPTBN2 GENE; ANIMAL; ANIMAL DISEASE; DNA SEQUENCE; DOG; DOG DISEASE; GENETICS; MUTATION; SPINOCEREBELLAR DEGENERATION;

CANIS FAMILIARIS;

ANIMALS; DOG DISEASES; DOGS; MUTATION; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SPECTRIN; SPINOCEREBELLAR ATAXIAS;

EID: 84863601420     PISSN: None     EISSN: 14712156     Source Type: Journal    
DOI: 10.1186/1471-2156-13-55     Document Type: Article

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