CEP-1, the Caenorhabditis elegans p53 Homolog, Mediates Opposing Longevity Outcomes in Mitochondrial Electron Transport Chain Mutants

PLoS Genetics

Volumn 10, Issue 2, 2014, Pages

  Baruah, Aiswarya ^a   Chang, Hsinwen ^a   Hall, Mathew ^b   Yuan, Jie ^a   Gordon, Sarah ^a   Johnson, Erik ^a   Shtessel, Ludmila L ^a   Yee, Callista ^c   Hekimi, Siegfried ^c   Derry, W Brent ^b   Lee, Siu Sylvia ^a  

^a Department of Obstetrics Gynecology   (United States)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FERRITIN; PROTEIN P53; REACTIVE OXYGEN METABOLITE; CAENORHABDITIS ELEGANS PROTEIN; CEP-1 PROTEIN, C ELEGANS; MULTIENZYME COMPLEX; TP53 PROTEIN, HUMAN; TRANSCRIPTOME;

APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; GENE MUTATION; GENE ONTOLOGY; GENE TARGETING; GENETIC ASSOCIATION; LIFESPAN; LONGEVITY; METABOLIC STRESS; MITOCHONDRIAL ELECTRON TRANSPORT CHAIN; MUTANT; NONHUMAN; RESPIRATORY CHAIN; SEQUENCE HOMOLOGY; AGING; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION PROFILING; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MITOCHONDRION; MUTATION; PATHOLOGY;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; GENE EXPRESSION PROFILING; LONGEVITY; MITOCHONDRIA; MUTATION; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTOME; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84901731023     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004097     Document Type: Article

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