Insulin/IGF-1 and hypoxia signaling act in concert to regulate iron homeostasis in Caenorhabditis elegans

PLoS Genetics

Volumn 8, Issue 3, 2012, Pages

  Ackerman, Daniel ^a   Gems, David ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; ADA 2 PROTEIN; AHA 1 PROTEIN; DAF 16 PROTEIN; DAF 2 PROTEIN; EGL 9 PROTEIN; FERRITIN; FTN 1 PROTEIN; H FERRITIN; HEAT SHOCK PROTEIN; HIF 1 PROTEIN; INSULIN; INSULIN RECEPTOR; IRON; MDL 1 PROTEIN; OXYGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; REGULATOR PROTEIN; REPRESSOR PROTEIN; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TRANSCRIPTION FACTOR FOXO; UNCLASSIFIED DRUG; VHL 1 PROTEIN; APOFERRITIN; CAENORHABDITIS ELEGANS PROTEIN; CULLIN; DAF 16 PROTEIN, C ELEGANS; DAF-16 PROTEIN, C ELEGANS; HEAT SHOCK FACTOR 1, C ELEGANS; HEAT SHOCK FACTOR-1, C ELEGANS; HIF 1 PROTEIN, C ELEGANS; HIF-1 PROTEIN, C ELEGANS; HISTONE ACETYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR; VHL 1 PROTEIN, C ELEGANS; VHL-1 PROTEIN, C ELEGANS;

ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; FTN 1 GENE; GENE ACTIVATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; HYPOXIA; IRON HOMEOSTASIS; IRON METABOLISM; METABOLIC REGULATION; MOLECULAR EVOLUTION; NONHUMAN; ANIMAL; ANOXIA; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUTATION; PHYSIOLOGICAL STRESS; SIGNAL TRANSDUCTION;

CAENORHABDITIS ELEGANS;

ANIMALS; ANOXIA; APOFERRITINS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CULLIN PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HISTONE ACETYLTRANSFERASES; INSULIN; INSULIN-LIKE GROWTH FACTOR I; IRON; MUTATION; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS;

EID: 84859233768     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002498     Document Type: Article

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