Chronic lymphocytic leukemia nurse-like cells express hepatocyte growth factor receptor (c-MET) and indoleamine 2,3-dioxygenase and display features of immunosuppressive type 2 skewed macrophages

Haematologica

Volumn 99, Issue 6, 2014, Pages 1078-1087

  Giannoni, Paolo ^a   Pietra, Gabriella ^a   Travaini, Giorgia ^b   Quarto, Rodolfo ^a   Shyti, Genti ^a   Benelli, Roberto ^b   Ottaggio, Laura ^b   Mingari, Maria Cristina ^a,b   Zupo, Simona ^b   Cutrona, Giovanna ^b   Pierri, Ivana ^a   Balleari, Enrico ^b   Pattarozzi, Alessandra ^c   Calvaruso, Marco ^d   Tripodo, Claudio ^d   Ferrarini, Manlio ^b   de Totero, Daniela ^b  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c Section of Pharmacology and Toxicology   (Italy)

^d Pathological Anatomy Tumor Immunology Unit Dept of Science for Health Promotion and Maternal Infantile 'G D'Alessandro'   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CD163 ANTIGEN; CD19 ANTIGEN; CD68 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 10; SCATTER FACTOR RECEPTOR; STAT3 PROTEIN; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTION FACTOR FOXP3; VIMENTIN; SCATTER FACTOR;

APOPTOSIS; ARTICLE; BONE MARROW BIOPSY; CD4+ CD25+ T LYMPHOCYTE; CELL EXPANSION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TYPE 2 MACROPHAGE; LEUKEMIA CELL; LYMPH NODE BIOPSY; MACROPHAGE; MONOCYTE; NURSE LIKE CELL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; WESTERN BLOTTING; CELL CULTURE; COCULTURE; DRUG EFFECTS; GENE EXPRESSION; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY; PHOSPHORYLATION; T LYMPHOCYTE SUBPOPULATION;

CELLS, CULTURED; COCULTURE TECHNIQUES; GENE EXPRESSION; HEPATOCYTE GROWTH FACTOR; HUMANS; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INTERLEUKIN-10; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MACROPHAGES; MONOCYTES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-MET; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTE SUBSETS;

EID: 84901725844     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2013.091405     Document Type: Article

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