Circulating microenvironment of CLL: Are nurse-like cells related to tumor-associated macrophages?

Blood Cells, Molecules, and Diseases

Volumn 50, Issue 4, 2013, Pages 263-270

  Filip, Agata A ^a   Ciseł, Bogumiła ^a   Koczkodaj, Dorota ^a   Wa̧sik Szczepanek, Ewa ^a   Piersiak, Tomasz ^a   Dmoszyńska, Anna ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

CLL; Gene expression profiling; Microenvironment; Nurse like cells; Tumor associated macrophages

Indexed keywords

BETA 2 MICROGLOBULIN; CD14 ANTIGEN; CELL ADHESION MOLECULE; CHEMOKINE; PROTEIN KINASE ZAP 70;

ADULT; AGED; APOPTOSIS; ARTICLE; B CELL LEUKEMIA; BONE MARROW; CANCER STAGING; CELL COUNT; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CHRONIC LYMPHATIC LEUKEMIA; DENDRITIC CELL; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; IN VITRO STUDY; LEUKEMIA CELL; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOLID TUMOR; T LYMPHOCYTE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT;

ADULT; AGED; AGED, 80 AND OVER; APOPTOSIS; CELL SURVIVAL; FEMALE; GENE EXPRESSION REGULATION, LEUKEMIC; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; LEUKOCYTE COUNT; MACROPHAGES; MALE; MIDDLE AGED; NEOPLASM STAGING; PHAGOCYTOSIS; PROGNOSIS; TRANSCRIPTOME; TUMOR MICROENVIRONMENT;

EID: 84875536950     PISSN: 10799796     EISSN: 10960961     Source Type: Journal    
DOI: 10.1016/j.bcmd.2012.12.003     Document Type: Article

References (31)

1. Hallek M., Pflug N. Chronic lymphocytic leukemia. Ann. Oncol. 2010, 21(Suppl. 7):vii154-vii164.
2. Müller-Hermerink H.K., Montserrat E., Catovsky D., Campo E., Harris N.L., Stein H. Chronic lymphocytic leukaemia/small lymphocytic leukaemia. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues 2008, 180-182. IARC Press, Lyon, France. fourth edition. S.H. Swerdlow, E. Campo, N.L. Harris, E.S. Jaffe, S.A. Pileri, H. Stein, J. Thiele, J.W. Vardiman (Eds.).
3. Giné E., Martinez A., Villamor N., López-Guillermo A., Camos M., Martinez D., Esteve J., Calvo X., Muntañola A., Abrisqueta P., Rozman M., Rozman C., Bosch F., Campo E., Montserrat E. Expanded and highly active proliferation centers identify a histological subtype of chronic lymphocytic leukemia ("accelerated" chronic lymphocytic leukemia) with aggressive clinical behavior. Haematologica 2010, 95:1526-1533.
4. Dal-Bo M., Bertoni F., Forconi F., Zucchetto A., Bomben R., Marasca R., Deaglio S., Laurenti L., Efremov D.G., Gaidano G., Del Poeta G., Gattei V. Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance. J. Transl. Med. 2009, 7:76. 10.1186/1479-5876-7-76.
5. Deaglio S., Malavasi F. Chronic lymphocytic leukemia microenvironment: shifting the balance from apoptosis to proliferation. Haematologica 2009, 94:752-756.
6. Deaglio S., Aydin S., Grand M.M., Vaisitti T., Bergui L., D'Arena G., Chiorino G., Malavasi F. CD38/CD31 interactions activate genetic pathways leading to proliferation and migration in chronic lymphocytic leukemia cells. Mol. Med. 2010, 16:87-91.
7. Granziero L., Ghia P., Circosta P., Gottardi D., Strola G., Guena M., Montagna L., Piccoli P., Chilosi M., Caligaris-Cappio F. Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia. Blood 2001, 97:2777-2783.
8. Burger J.A., Quiroga M.P., Hartmann E., Bürkle A., Wierda W.G., Keating M.J., Rosenwald A. High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell co-cultures and after BCR stimulation. Blood 2009, 113:3050-3058.
9. Ghia P., Chiorazzi N., Stamatopoulos K. Microenvironmental influences in chronic lymphocytic leukemia: the role of antigen stimulation. J. Int. Med. 2008, 264:549-562.
10. Herishanu Y., Pérez-Galán P., Liu D., Biancotto A., Pittaluga S., Vire B., Gibellini F., Njuguna N., Lee E., Stennett L., Raghavachari N., Liu P., McCoy J.P., Raffeld M., Stetler-Stevenson M., Yuan C., Sherry R., Arthur D.C., Maric I., White T., Marti G.E., Munson P., Wilson W.H., Wiestner A. The lymph node microenvironment promotes B-cell receptor signaling, NF-(kappa)B activation, and tumor proliferation in chronic lymphocytic leukemia. Blood 2011, 117:563-574.
11. Burger J.A., Tsukada N., Burger M., Zvaifler N.J., Dell'Aquilla M., Kipps T.J. Blood derived nurse cells protect leukemia B cells from spontaneous apoptosis through stromal-cell derived factor-1. Blood 2000, 96:2655-2663.
12. Tsukada N., Burger A.J., Zvaifler N.J., Kipps T.J. Distinctive features of "nurselike" cells that differentiate in the context of chronic lymphocytic leukemia. Blood 2002, 99:1030-1037.
13. Sica A., Larghi P., Mancino A., Rubino L., Porta C., Totaro M.G., Rimoldi M., Biswas S.K., Allavena P., Mantovani A. Macrophage polarization in tumour progression. Semin. Cancer Biol. 2008, 18:349-355.
14. Mancino A., Lawerence T. Nuclear factor-κB and tumor associated macrophages. Clin. Cancer Res. 2010, 16:784-789.
15. Steidl C., Lee T., Shah S.P., Farinha P., Han G., Nayar T., Delaney A., Jones S.J., Iqbal J., Weisenburger D.D., Bast M.A., Rosenwald A., Muller-Hermelink H.K., Rimsza L.M., Campo E., Delabie J., Braziel R.M., Cook J.R., Tubbs R.R., Jaffe E.S., Lenz G., Connors J.M., Staudt L.M., Chan W.C., Gascoyne R.D. Tumor associated macrophages and survival in classic Hodgkin's lymphoma. N. Engl. J. Med. 2010, 362:875-885.
16. Filip A.A., Koczkodaj D., Kubiatowski T., Wasik-Szczepanek E., Dmoszynska A. The outgrowth of CLL nurselike cells in vitro, and its relation to clinical and hematological parameters. Blood 2009, 114:932.
17. Cortez-Retamozo V., Etzrodt M., Newton A., Rauch P.J., Chudnovskiy A., Berger C. Origins of tumor-associated macrophages and neutrophils. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:2491-2496.
18. Solinas G., Germano G., Mantovani A., Allavena P. Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation. J. Leukoc. Biol. 2009, 86:1065-1073.
19. Ysebaert L., Fournié J.J. Genomic and phenotypic characterization of nurse-like cells that promote drug resistance in chronic lymphocytic leukemia. Leuk. Lymphoma 2011, 52:1404-1406.
20. Nucera S., Biziato D., De Palma M. The interplay between macrophages and angiogenesis in development, tissue injury and regeneration. Int. J. Dev. Biol. 2011, 55:495-503.
21. Mitchell A.J., Pradel L.C., Chasson L., Van Rooijen N., Grau G.E., Hunt N.H., Chimini G. Technical advance: autofluorescence as a tool for myeloid cell analysis. J. Leukoc. Biol. 2010, 88:597-603.
22. Van Bockstaele F., Verhasselt B., Philippe J. Prognostic markers in chronic lymphocytic leukemia: a comprehensive review. Blood Rev. 2009, 23:25-47.
23. Burgess M., Cheung C., Chambers L., Ravindranath K., Minhas G., Knopp L., Mollee P., McMillan N.A., Gill D. CCL2 and CXCL2 enhance the survival of primary chronic lymphocytic leukaemia cells in vitro. Leuk. Lymphoma 2012, 53:1988-1998.
24. Nishio M., Endo T., Tsukada N., Ohata J., Kitada S., Reed J.C., Zvaifler N.J., Kipps T.J. Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1α. Blood 2005, 106:1012-1020.
25. Wierda W.G., Johnson M.M., Do K.-A., Manshouri T., Dey A., O'Brien S., Giles F.J., Kantarjian H., Thomas D., Faderl S., Lerner S., Keating M., Albitar M. Plasma interleukin 8 level predicts for survival in chronic lymphocytic leukaemia. Br. J. Haematol. 2003, 120:452-456.
26. Stamatopoulos B., Haibe-Kains B., Equeter C., Meuleman N., Soree A., De Bruyn C., Hanosset D., Bron D., Martiat P., Lagneaux L. Gene expression profiling reveals differences in microenvironment interaction between patients with chronic lymphocytic leukemia expressing high versus low ZAP70 mRNA. Haematologica 2009, 94:790-799.
27. Kang J.C., Chen J.S., Lee C.H., Chang J.J., Shieh Y.S. Intratumoral macrophage counts correlate with tumor progression in colorectal cancer. J. Surg. Oncol. 2010, 102:242-248.
28. Rigo A., Gottardi M., Zamò A., Mauri P., Bonifacio M., Krampera M., Damiani E., Pizzolo G., Vinante F. Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12. Mol. Cancer 2010, 9:273. 10.1186/1476-4598-9-273.
29. Campbell M.J., Tonlaar N.Y., Garwood E.R., Huo D., Moore D.H., Khramtsov A.I., Au A., Baehner F., Chen Y., Malaka D.O., Lin A., Adeyanju O.O., Li S., Gong C., McGrath M., Olopade O.I., Esserman L.J. Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome. Breast Cancer Res. Treat. 2011, 128:703-711.
30. Steidl C., Farinha P., Gascoyne R.D. Macrophages predict treatment outcome in Hodgkin's lymphoma. Haematologica 2011, 96:186-189.
31. Burger J.A. Nurture versus nature: the microenvironment in chronic lymphocytic leukemia. Hematology Am. Soc. Hematol. Educ. Program 2011, 2011:96-103.