메뉴 건너뛰기




Volumn 306, Issue 11, 2014, Pages

Coinjection of CCK and leptin reduces food intake via increased CART/TRH and reduced AMPK phosphorylation in the hypothalamus

Author keywords

Cholecystokinin; Food intake; Leptin; Midbrain transection

Indexed keywords

AGOUTI RELATED PROTEIN; CHOLECYSTOKININ; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN; PROTIRELIN; RECOMBINANT LEPTIN; STAT3 PROTEIN;

EID: 84901703541     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00664.2013     Document Type: Article
Times cited : (43)

References (56)
  • 3
    • 0030931678 scopus 로고    scopus 로고
    • Synergistic interaction between leptin and cholecystokinin to reduce short-term food intake in lean mice
    • Barrachina MD, Martinez V, Wang L, Wei JY, Tache Y. Synergistic interaction between leptin and cholecystokinin to reduce short-term food intake in lean mice. Proc Natl Acad Sci USA 94: 10455-10460, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10455-10460
    • Barrachina, M.D.1    Martinez, V.2    Wang, L.3    Wei, J.Y.4    Tache, Y.5
  • 4
    • 2342439732 scopus 로고    scopus 로고
    • Leptin signaling in the central nervous system and the periphery
    • Bjorbaek C, Kahn BB. Leptin signaling in the central nervous system and the periphery. Recent Prog Horm Res 59: 305-331, 2004.
    • (2004) Recent Prog Horm Res , vol.59 , pp. 305-331
    • Bjorbaek, C.1    Kahn, B.B.2
  • 5
    • 0033406160 scopus 로고    scopus 로고
    • Hypothalamic cocaine-and amphetamine-regulated transcript (CART) neurons: Histochemical relationship to thyrotropin-releasing hormone, melanin-concentrating hormone, orexin/hypocretin and neuropeptide Y
    • Broberger C. Hypothalamic cocaine-and amphetamine-regulated transcript (CART) neurons: histochemical relationship to thyrotropin-releasing hormone, melanin-concentrating hormone, orexin/hypocretin and neuropeptide Y. Brain Res 848: 101-113, 1999.
    • (1999) Brain Res , vol.848 , pp. 101-113
    • Broberger, C.1
  • 6
    • 0021740636 scopus 로고
    • Bilateral midbrain transections block the behavioral effects of cholecystokinin on feeding and exploration in rats
    • Crawley JN, Kiss JZ, Mezey E. Bilateral midbrain transections block the behavioral effects of cholecystokinin on feeding and exploration in rats. Brain Res 322: 316-321, 1984.
    • (1984) Brain Res , vol.322 , pp. 316-321
    • Crawley, J.N.1    Kiss, J.Z.2    Mezey, E.3
  • 8
    • 84863233973 scopus 로고    scopus 로고
    • Leptin resistance in vagal afferent neurons inhibits cholecystokinin signaling and satiation in diet induced obese rats
    • de Lartigue G, Barbier de la Serre C, Espero E, Lee J, Raybould HE. Leptin resistance in vagal afferent neurons inhibits cholecystokinin signaling and satiation in diet induced obese rats. PLoS One 7: e32967, 2012.
    • (2012) PLoS One , vol.7
    • de Lartigue, G.1    Barbier de la Serre, C.2    Espero, E.3    Lee, J.4    Raybould, H.E.5
  • 9
    • 77954934605 scopus 로고    scopus 로고
    • EGR1 Is a target for cooperative interactions between cholecystokinin and leptin, and inhibition by ghrelin, in vagal afferent neurons
    • de Lartigue G, Lur G, Dimaline R, Varro A, Raybould H, Dockray GJ. EGR1 Is a target for cooperative interactions between cholecystokinin and leptin, and inhibition by ghrelin, in vagal afferent neurons. Endocrinology 151: 3589-3599, 2010.
    • (2010) Endocrinology , vol.151 , pp. 3589-3599
    • de Lartigue, G.1    Lur, G.2    Dimaline, R.3    Varro, A.4    Raybould, H.5    Dockray, G.J.6
  • 10
    • 0028947053 scopus 로고
    • PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine
    • Douglass J, McKinzie AA, Couceyro P. PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine. J Neurosci 15: 2471-2481, 1995.
    • (1995) J Neurosci , vol.15 , pp. 2471-2481
    • Douglass, J.1    McKinzie, A.A.2    Couceyro, P.3
  • 15
    • 0034671287 scopus 로고    scopus 로고
    • Association of cocaine-and amphetamine-regulated transcript-immunoreactive elements with thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and its role in the regulation of the hypothalamic-pituitary-thyroid axis during fasting
    • Fekete C, Mihaly E, Luo LG, Kelly J, Clausen JT, Mao Q, Rand WM, Moss LG, Kuhar M, Emerson CH, Jackson IM, Lechan RM. Association of cocaine-and amphetamine-regulated transcript-immunoreactive elements with thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and its role in the regulation of the hypothalamic-pituitary-thyroid axis during fasting. J Neurosci 20: 9224-9234, 2000.
    • (2000) J Neurosci , vol.20 , pp. 9224-9234
    • Fekete, C.1    Mihaly, E.2    Luo, L.G.3    Kelly, J.4    Clausen, J.T.5    Mao, Q.6    Rand, W.M.7    Moss, L.G.8    Kuhar, M.9    Emerson, C.H.10    Jackson, I.M.11    Lechan, R.M.12
  • 16
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature 395: 763-770, 1998.
    • (1998) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 18
    • 0024548301 scopus 로고
    • Reduction of food intake by central administration of cholecystokinin octapeptide in the rat is dependent upon inhibition of brain peptidases
    • Griesbacher T, Leighton GE, Hill RG, Hughes J. Reduction of food intake by central administration of cholecystokinin octapeptide in the rat is dependent upon inhibition of brain peptidases. Br J Pharmacol 96: 236-242, 1989.
    • (1989) Br J Pharmacol , vol.96 , pp. 236-242
    • Griesbacher, T.1    Leighton, G.E.2    Hill, R.G.3    Hughes, J.4
  • 20
    • 79953197601 scopus 로고    scopus 로고
    • Synergistic interaction between leptin and cholecystokinin in the rat nodose ganglia is mediated by PI3K and STAT3 signaling pathways: Implications for leptin as a regulator of short term satiety
    • Heldsinger A, Grabauskas G, Song I, Owyang C. Synergistic interaction between leptin and cholecystokinin in the rat nodose ganglia is mediated by PI3K and STAT3 signaling pathways: implications for leptin as a regulator of short term satiety. J Biol Chem 286: 11707-11715, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 11707-11715
    • Heldsinger, A.1    Grabauskas, G.2    Song, I.3    Owyang, C.4
  • 21
    • 20844451123 scopus 로고    scopus 로고
    • AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
    • Kahn BB, Alquier T, Carling D, Hardie DG. AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 1: 15-25, 2005.
    • (2005) Cell Metab , vol.1 , pp. 15-25
    • Kahn, B.B.1    Alquier, T.2    Carling, D.3    Hardie, D.G.4
  • 24
    • 0032472826 scopus 로고    scopus 로고
    • Cocaine-and amphetamine-regulated transcript peptide immunohistochemical localization in the rat brain
    • Koylu EO, Couceyro PR, Lambert PD, Kuhar MJ. Cocaine-and amphetamine-regulated transcript peptide immunohistochemical localization in the rat brain. J Comp Neurol 391: 115-132, 1998.
    • (1998) J Comp Neurol , vol.391 , pp. 115-132
    • Koylu, E.O.1    Couceyro, P.R.2    Lambert, P.D.3    Kuhar, M.J.4
  • 26
    • 23044452846 scopus 로고    scopus 로고
    • Leptin enhances feeding suppression and neural activation produced by systemically administered bombesin
    • Ladenheim EE, Emond M, Moran TH. Leptin enhances feeding suppression and neural activation produced by systemically administered bombesin. Am J Physiol Regul Integr Comp Physiol 289: R473-R477, 2005.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.289
    • Ladenheim, E.E.1    Emond, M.2    Moran, T.H.3
  • 28
    • 0021905218 scopus 로고
    • Cholecystokinin bioactivity in human plasma. Molecular forms, responses to feeding, and relationship to gallbladder contraction
    • Liddle RA, Goldfine ID, Rosen MS, Taplitz RA, Williams JA. Cholecystokinin bioactivity in human plasma. Molecular forms, responses to feeding, and relationship to gallbladder contraction. J Clin Invest 75: 1144-1152, 1985.
    • (1985) J Clin Invest , vol.75 , pp. 1144-1152
    • Liddle, R.A.1    Goldfine, I.D.2    Rosen, M.S.3    Taplitz, R.A.4    Williams, J.A.5
  • 30
    • 60949091763 scopus 로고    scopus 로고
    • Protein components of the blood-brain barrier (BBB) in the brainstem area postrema-nucleus tractus solitarius region
    • Maolood N, Meister B. Protein components of the blood-brain barrier (BBB) in the brainstem area postrema-nucleus tractus solitarius region. J Chem Neuroanat 37: 182-195, 2009.
    • (2009) J Chem Neuroanat , vol.37 , pp. 182-195
    • Maolood, N.1    Meister, B.2
  • 32
    • 0029895233 scopus 로고    scopus 로고
    • Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization
    • Mercer JG, Hoggard N, Williams LM, Lawrence CB, Hannah LT, Trayhurn P. Localization of leptin receptor mRNA and the long form splice variant (Ob-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization. FEBS Lett 387: 113-116, 1996.
    • (1996) FEBS Lett , vol.387 , pp. 113-116
    • Mercer, J.G.1    Hoggard, N.2    Williams, L.M.3    Lawrence, C.B.4    Hannah, L.T.5    Trayhurn, P.6
  • 34
    • 17044441490 scopus 로고    scopus 로고
    • Peripheral administration of cholecystokinin activates c-fos expression in the locus coeruleus/subcoeruleus nucleus, dorsal vagal complex and paraventricular nucleus via capsaicinsensitive vagal afferents and CCK-A receptors in the rat
    • Monnikes H, Lauer G, Arnold R. Peripheral administration of cholecystokinin activates c-fos expression in the locus coeruleus/subcoeruleus nucleus, dorsal vagal complex and paraventricular nucleus via capsaicinsensitive vagal afferents and CCK-A receptors in the rat. Brain Res 770: 277-288, 1997.
    • (1997) Brain Res , vol.770 , pp. 277-288
    • Monnikes, H.1    Lauer, G.2    Arnold, R.3
  • 36
    • 58749086043 scopus 로고    scopus 로고
    • The geometry of leptin action in the brain: More complicated than a simple ARC
    • Myers MG Jr, Munzberg H, Leinninger GM, Leshan RL. The geometry of leptin action in the brain: more complicated than a simple ARC. Cell Metab 9: 117-123, 2009.
    • (2009) Cell Metab , vol.9 , pp. 117-123
    • Myers Jr., M.G.1    Munzberg, H.2    Leinninger, G.M.3    Leshan, R.L.4
  • 37
    • 0032708056 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors
    • Noble F, Wank SA, Crawley JN, Bradwejn J, Seroogy KB, Hamon M, Roques BP. International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors. Pharmacol Rev 51: 745-781, 1999.
    • (1999) Pharmacol Rev , vol.51 , pp. 745-781
    • Noble, F.1    Wank, S.A.2    Crawley, J.N.3    Bradwejn, J.4    Seroogy, K.B.5    Hamon, M.6    Roques, B.P.7
  • 39
    • 3843117676 scopus 로고    scopus 로고
    • Cooperative activation of cultured vagal afferent neurons by leptin and cholecystokinin
    • Peters JH, Karpiel AB, Ritter RC, Simasko SM. Cooperative activation of cultured vagal afferent neurons by leptin and cholecystokinin. Endocrinology 145: 3652-3657, 2004.
    • (2004) Endocrinology , vol.145 , pp. 3652-3657
    • Peters, J.H.1    Karpiel, A.B.2    Ritter, R.C.3    Simasko, S.M.4
  • 40
    • 33750300106 scopus 로고    scopus 로고
    • Modulation of vagal afferent excitation and reduction of food intake by leptin and cholecystokinin
    • Peters JH, Simasko SM, Ritter RC. Modulation of vagal afferent excitation and reduction of food intake by leptin and cholecystokinin. Physiol Behav 89: 477-485, 2006.
    • (2006) Physiol Behav , vol.89 , pp. 477-485
    • Peters, J.H.1    Simasko, S.M.2    Ritter, R.C.3
  • 41
    • 84859104548 scopus 로고    scopus 로고
    • Possible involvement of melanocortin-4-receptor and AMP-activated protein kinase in the interaction of glucagon-like peptide-1 and leptin on feeding in rats
    • Poleni PE, Akieda-Asai S, Koda S, Sakurai M, Bae CR, Senba K, Cha YS, Furuya M, Date Y. Possible involvement of melanocortin-4-receptor and AMP-activated protein kinase in the interaction of glucagon-like peptide-1 and leptin on feeding in rats. Biochem Biophys Res Commun 420: 36-41, 2012.
    • (2012) Biochem Biophys Res Commun , vol.420 , pp. 36-41
    • Poleni, P.E.1    Akieda-Asai, S.2    Koda, S.3    Sakurai, M.4    Bae, C.R.5    Senba, K.6    Cha, Y.S.7    Furuya, M.8    Date, Y.9
  • 42
    • 40449138261 scopus 로고    scopus 로고
    • The area postrema: A brain monitor and integrator of systemic autonomic state
    • Price CJ, Hoyda TD, Ferguson AV. The area postrema: a brain monitor and integrator of systemic autonomic state. Neuroscientist 14: 182-194, 2008.
    • (2008) Neuroscientist , vol.14 , pp. 182-194
    • Price, C.J.1    Hoyda, T.D.2    Ferguson, A.V.3
  • 43
    • 33745199458 scopus 로고    scopus 로고
    • Developing a head for energy sensing: AMP-activated protein kinase as a multifunctional metabolic sensor in the brain
    • Ramamurthy S, Ronnett GV. Developing a head for energy sensing: AMP-activated protein kinase as a multifunctional metabolic sensor in the brain. J Physiol 574: 85-93, 2006.
    • (2006) J Physiol , vol.574 , pp. 85-93
    • Ramamurthy, S.1    Ronnett, G.V.2
  • 44
    • 36549061906 scopus 로고    scopus 로고
    • Mechanisms of CCK signaling from gut to brain
    • Raybould HE. Mechanisms of CCK signaling from gut to brain. Curr Opin Pharmacol 7: 570-574, 2007.
    • (2007) Curr Opin Pharmacol , vol.7 , pp. 570-574
    • Raybould, H.E.1
  • 45
    • 0242694943 scopus 로고    scopus 로고
    • Hindbrain noradrenergic lesions attenuate anorexia and alter central cFos expression in rats after gastric viscerosensory stimulation
    • Rinaman L. Hindbrain noradrenergic lesions attenuate anorexia and alter central cFos expression in rats after gastric viscerosensory stimulation. J Neurosci 23: 10084-10092, 2003.
    • (2003) J Neurosci , vol.23 , pp. 10084-10092
    • Rinaman, L.1
  • 46
    • 0034984796 scopus 로고    scopus 로고
    • Leptin and tumor necrosis factor-alpha induce the tyrosine phosphorylation of signal transducer and activator of transcription proteins in the hypothalamus of normal rats in vivo
    • Rizk NM, Stammsen D, Preibisch G, Eckel J. Leptin and tumor necrosis factor-alpha induce the tyrosine phosphorylation of signal transducer and activator of transcription proteins in the hypothalamus of normal rats in vivo. Endocrinology 142: 3027-3032, 2001.
    • (2001) Endocrinology , vol.142 , pp. 3027-3032
    • Rizk, N.M.1    Stammsen, D.2    Preibisch, G.3    Eckel, J.4
  • 48
    • 0019890231 scopus 로고
    • Abdominal vagotomy blocks the satiety effect of cholecystokinin in the rat
    • Smith GP, Jerome C, Cushin BJ, Eterno R, Simansky KJ. Abdominal vagotomy blocks the satiety effect of cholecystokinin in the rat. Science 213: 1036-1037, 1981.
    • (1981) Science , vol.213 , pp. 1036-1037
    • Smith, G.P.1    Jerome, C.2    Cushin, B.J.3    Eterno, R.4    Simansky, K.J.5
  • 49
    • 0022149006 scopus 로고
    • Afferent axons in abdominal vagus mediate satiety effect of cholecystokinin in rats
    • Smith GP, Jerome C, Norgren R. Afferent axons in abdominal vagus mediate satiety effect of cholecystokinin in rats. Am J Physiol Regul Integr Comp Physiol 249: R638-R641, 1985.
    • (1985) Am J Physiol Regul Integr Comp Physiol , vol.249
    • Smith, G.P.1    Jerome, C.2    Norgren, R.3
  • 50
    • 0024162579 scopus 로고
    • Capsaicin application to central or peripheral vagal fibers attenuates CCK satiety
    • South EH, Ritter RC. Capsaicin application to central or peripheral vagal fibers attenuates CCK satiety. Peptides 9: 601-612, 1988.
    • (1988) Peptides , vol.9 , pp. 601-612
    • South, E.H.1    Ritter, R.C.2
  • 53
    • 0034464038 scopus 로고    scopus 로고
    • Central administration of cocaine-amphetamine-regulated transcript activates hypothalamic neuroendocrine neurons in the rat
    • Vrang N, Larsen PJ, Kristensen P, Tang-Christensen M. Central administration of cocaine-amphetamine-regulated transcript activates hypothalamic neuroendocrine neurons in the rat. Endocrinology 141: 794-801, 2000.
    • (2000) Endocrinology , vol.141 , pp. 794-801
    • Vrang, N.1    Larsen, P.J.2    Kristensen, P.3    Tang-Christensen, M.4
  • 54
    • 0034714049 scopus 로고    scopus 로고
    • Synergistic interaction between CCK and leptin to regulate food intake
    • Wang L, Barachina MD, Martinez V, Wei JY, Tache Y. Synergistic interaction between CCK and leptin to regulate food intake. Regul Pept 92: 79-85, 2000.
    • (2000) Regul Pept , vol.92 , pp. 79-85
    • Wang, L.1    Barachina, M.D.2    Martinez, V.3    Wei, J.Y.4    Tache, Y.5
  • 55
    • 0021433344 scopus 로고
    • Cholecystokinin persistently suppresses meal size but not food intake in free-feeding rats
    • West DB, Fey D, Woods SC. Cholecystokinin persistently suppresses meal size but not food intake in free-feeding rats. Am J Physiol Regul Integr Comp Physiol 246: R776-R787, 1984.
    • (1984) Am J Physiol Regul Integr Comp Physiol , vol.246
    • West, D.B.1    Fey, D.2    Woods, S.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.