Synergistic interaction between leptin and cholecystokinin in the rat nodose ganglia is mediated by PI3K and STAT3 signaling pathways: Implications for leptin as a regulator of short term satiety

Journal of Biological Chemistry

Volumn 286, Issue 13, 2011, Pages 11707-11715

  Heldsinger, Andrea ^a   Grabauskas, Gintautas ^a   Song, Il ^a   Owyang, Chung ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EATING DISORDERS; IMMUNOBLOTS; INPUT RESISTANCE; INTRACELLULAR SIGNALING PATHWAYS; LEPTIN RECEPTORS; LIPOFECTAMINE; LY294002; MEMBRANE DEPOLARIZATION; NEURONAL FIRINGS; PATCH-CLAMP STUDIES; SHORT TERM; SIGNALING CASCADES; SIGNALING MOLECULES; SIGNALING PATHWAYS; SYNERGISTIC ACTION; SYNERGISTIC INTERACTION; WHOLE CELL PATCH CLAMP; WORTMANNIN;

DEPOLARIZATION; GENES; HORMONES; PHOSPHORYLATION;

SIGNALING;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; CHOLECYSTOKININ A RECEPTOR; CHOLECYSTOKININ OCTAPEPTIDE; EXOENZYME C3; LEPTIN; LEPTIN RECEPTOR; LIPOFECTAMINE; MITOGEN ACTIVATED PROTEIN KINASE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; POTASSIUM CHANNEL; PROTEIN TYROSINE KINASE; STAT3 PROTEIN; WORTMANNIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE RESISTANCE; CONTROLLED STUDY; GENE SILENCING; GENETIC TRANSFECTION; INTRACELLULAR RECORDING; MALE; MOLECULAR INTERACTION; NODOSE GANGLION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; SATIETY; SIGNAL TRANSDUCTION;

ANIMALS; GENE SILENCING; ION CHANNEL GATING; JANUS KINASE 2; LEPTIN; MALE; MEMBRANE POTENTIALS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NEURONS; NODOSE GANGLION; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; POTASSIUM CHANNELS; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CHOLECYSTOKININ; RECEPTORS, LEPTIN; SATIETY RESPONSE; SIGNAL TRANSDUCTION; SINCALIDE; STAT3 TRANSCRIPTION FACTOR; TIME FACTORS;

RATTUS;

EID: 79953197601     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.198945     Document Type: Article

References (36)

1. Maffei, M., Halaas, J., Ravussin, E., Pratley, R. E., Lee, G. H., Zhang, Y., Fei, H., Kim, S., Lallone, R., and Ranganathan, S. (1995) Nat. Med. 1, 1155-1161
2. Loftus, T. M. (1999) Semin. Cell Dev. Biol. 10, 11-18
3. Pan, W., and Kastin, A. J. (2001) Life Sci. 68, 2705-2714
4. Lee, G. H., Proenca, R., Montez, J. M., Carroll, K. M., Darvishzadeh, J. G., Lee, J. I., and Friedman, J. M. (1996) Nature 379, 632-635
5. Fei, H., Okano, H. J., Li, C., Lee, G. H., Zhao, C., Darnell, R., and Friedman, J. M. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 7001-7005
6. Masuzaki, H., Ogawa, Y., Sagawa, N., Hosoda, K., Matsumoto, T., Mise, H., Nishimura, H., Yoshimasa, Y., Tanaka, I., Mori, T., and Nakao, K. (1997) Nat. Med. 3, 1029-1033
7. Sobhani, I., Bado, A., Vissuzaine, C., Buyse, M., Kermorgant, S., Laigneau, J. P., Attoub, S., Lehy, T., Henin, D., Mignon, M., and Lewin, M. J. (2000) Gut 47, 178-183
8. Bado, A., Levasseur, S., Attoub, S., Kermorgant, S., Laigneau, J. P., Bortoluzzi, M. N., Moizo, L., Lehy, T., Guerre-Millo, M., Le Marchand-Brustel, Y., and Lewin, M. J. (1998) Nature 394, 790-793
9. Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., and Friedman, J. M. (1994) Nature 372, 425-432
10. Björnholm, M., Münzberg, H., Leshan, R. L., Villanueva, E. C., Bates, S. H., Louis, G. W., Jones, J. C., Ishida-Takahashi, R., Bjørbaek, C., and Myers, M. G., Jr. (2007) J. Clin. Invest. 117, 1354-1360
11. Montague, C. T., Farooqi, I. S., Whitehead, J. P., Soos, M. A., Rau, H., Wareham, N. J., Sewter, C. P., Digby, J. E., Mohammed, S. N., Hurst, J. A., Cheetham, C. H., Earley, A. R., Barnett, A. H., Prins, J. B., and O'Rahilly, S. (1997) Nature 387, 903-908
12. White, D. W., Kuropatwinski, K. K., Devos, R., Baumann, H., and Tartaglia, L. A. (1997) J. Biol. Chem. 272, 4065-4071
13. Banks, A. S., Davis, S. M., Bates, S. H., and Myers, M. G., Jr. (2000) J. Biol. Chem. 275, 14563-14572
14. Jiang, L., Li, Z., and Rui, L. (2008) J. Biol. Chem. 283, 28066-28073
15. Crawley, J. N., and Corwin, R. L. (1994) Peptides 15, 731-755
16. Weatherford, S. C., Laughton, W. B., Salabarria, J., Danho, W., Tilley, J. W., Netterville, L. A., Schwartz, G. J., and Moran, T. H. (1993) Am. J. Physiol. Regul. Integr. Comp. Physiol. 264, R244-249
17. Baldwin, B. A., Parrott, R. F., and Ebenezer, I. S. (1998) Prog. Neurobiol. 55, 477-507
18. Passaro, E., Jr., Debas, H., Oldendorf, W., and Yamada, T. (1982) Brain Res. 241, 335-340
19. Moran, T. H., Ameglio, P. J., Schwartz, G. J., and McHugh, P. R. (1992) Am. J. Physiol. Regul. Integr. Comp. Physiol. 262, R46-R50
20. Ritter, R. C., Covasa, M., and Matson, C. A. (1999) Neuropeptides 33, 387-399
21. Burdyga, G., Spiller, D., Morris, R., Lal, S., Thompson, D. G., Saeed, S., Dimaline, R., Varro, A., and Dockray, G. J. (2002) Neuroscience 109, 339-347
22. Zarbin, M. A., Wamsley, J. K., Innis, R. B., and Kuhar, M. J. (1981) Life Sci. 29, 697-705
23. Barrachina, M. D., Martínez, V., Wang, L., Wei, J. Y., and Taché, Y. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 10455-10460
24. Peters, J. H., Karpiel, A. B., Ritter, R. C., and Simasko, S. M. (2004) Endocrinology 145, 3652-3657
25. Williams, D. L., Baskin, D. G., and Schwartz, M. W. (2009) Am. J. Physiol. Regul. Integr. Comp. Physiol. 297, R1238-1246
26. Owyang, C., Hao, Y., and Li, Y. (2008) Gastroenterology 134, Suppl. 1, A-96-A-97 (abstr.)
27. Tsunoda, Y., Yoshida, H., Africa, L., Steil, G. J., and Owyang, C. (1996) Biochem. Biophys. Res. Commun. 227, 876-884
28. Nozu, F., Owyang, C., and Tsunoda, Y. (2000) Eur. J. Cell Biol. 79, 803-809
29. Peters, J. H., Ritter, R. C., and Simasko, S. M. (2006) Am. J. Physiol. Cell Physiol. 290, C427-432
30. Frontini, A., Bertolotti, P., Tonello, C., Valerio, A., Nisoli, E., Cinti, S., and Giordano, A. (2008) Brain Res. 1215, 105-115
31. Ruiter, M., Duffy, P., Simasko, S., and Ritter, R. C. (2010) Endocrinology 151, 1509-1519
32. Sutton, G. M., Patterson, L. M., and Berthoud, H. R. (2004) J. Neurosci. 24, 10240-10247
33. Zhang, X., Wrzeszczynska, M. H., Horvath, C. M., and Darnell, J. E., Jr. (1999) Mol. Cell. Biol. 19, 7138-7146
34. Wang, Y. H., Taché, Y., Sheibel, A. B., Go, V. L., and Wei, J. Y. (1997) Am. J. Physiol. Regul. Integr. Comp. Physiol. 273, R833-837
35. Grill, H. J. (2010) Front. Neuroendocrinol. 31, 61-78
36. de Lartigue, G., Lur, G., Dimaline, R., Varro, A., Raybould, H., and Dockray, G. J. (2010) Endocrinology 151, 3589-3599