Protein components of the blood-brain barrier (BBB) in the brainstem area postrema-nucleus tractus solitarius region

Journal of Chemical Neuroanatomy

Volumn 37, Issue 3, 2009, Pages 182-195

  Maolood, Nasren ^a   Meister, Björn ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

CD11b; Claudin 5; EBA; GFAP; GLUT1; Transferrin receptor; ZO 1

Indexed keywords

ALPHA INTERMEDIN; ANTIGEN; ANTISERUM; CD11B ANTIGEN; CLAUDIN 5; CYCLIC AMP; CYCLIC AMP REGULATED PHOSPHOPROTEIN 32; DOPAMINE; ENDOTHELIAL BARRIER ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUCOSE TRANSPORTER 1; LAMININ; NEUROPEPTIDE Y; PHOSPHOPROTEIN; PROTEIN ZO1; PROTEOCHONDROITIN SULFATE; RAT ENDOTHELIAL CELL ANTIGEN 1; RECA PROTEIN; SMOOTH MUSCLE ACTIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA POSTREMA; ARTICLE; ASTROCYTE; BASEMENT MEMBRANE; BLOOD BRAIN BARRIER; BRAIN CIRCULATION; BRAIN STEM; CELLULAR DISTRIBUTION; ENDOTHELIUM CELL; ENERGY BALANCE; GLIA CELL; IMMUNOREACTIVITY; MALE; MICROGLIA; NONHUMAN; PERICYTE; PERIKARYON; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONTENT; RAT; REGULATORY MECHANISM; SOLITARY TRACT NUCLEUS; TANYCYTE; THALAMUS DORSOMEDIAL NUCLEUS; TIGHT JUNCTION; VASCULAR SMOOTH MUSCLE;

ANIMALS; AREA POSTREMA; BLOOD-BRAIN BARRIER; BODY WEIGHT; BRAIN STEM; EATING; ENERGY METABOLISM; MALE; MYOCYTES, SMOOTH MUSCLE; NERVE TISSUE PROTEINS; NEUROGLIA; RATS; RATS, SPRAGUE-DAWLEY; SOLITARY NUCLEUS; TIGHT JUNCTIONS;

EID: 60949091763     PISSN: 08910618     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchemneu.2008.12.007     Document Type: Article

References (56)

1. Abbott J.N., Rönnbäck L., and Hansson E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat. Rev. 7 (2006) 41-53
2. Adipudi V., and Simansky K.J. Lesions of area postrema attenuate but do not prevent anorectic action of peripheral serotonin in rats. Am. J. Physiol. 269 (1995) R1314-R1320
3. Banks W.A. The blood-brain barrier as a regulatory interface in the gut-brain axes. Physiol. Behav. 30 (2006) 472-476
4. Banks W.A. Blood-brain barrier and energy balance. Obesity 5 (2006) 234S-237S
5. Berthoud H.R. Neural control of appetite: cross-talk between homeostatic and non-homeostatic systems. Appetite 43 (2004) 315-317
6. Boado R.J., and Pardridge W.M. The brain-type glucose transporter mRNA is specifically expressed at the blood-brain barrier. Biochem. Biophys. Res. Commun. 166 (1990) 174-179
7. Borison H.L., Borison R., and McCarthy L.E. Brain stem penetration by horseradish peroxidase from the cerebrospinal fluid spaces in the cat. Exp. Neurol. 69 (1980) 271-289
8. Borison H.L., Borison R., and McCarthy L.E. Role of the area postrema in vomiting and related functions. Fed. Proc. 43 (1984) 2955-2958
9. Broadwell R.D., and Brightman M.W. Entry of peroxidase into neurons of the cerebral and peripheral nervous systems from extracerebral and cerebral blood. J. Comp. Neurol. 166 (1976) 257-284
10. Broadwell R.D., Balin B.J., Salcman M., and Kaplan R.S. Brain-blood barrier? Yes and no. Proc. Natl. Acad. Sci. USA 80 (1983) 7352-7356
11. Cassella J.P., Lawrenson J.G., Lawrence L., and Firth J.A. Differential distribution of an endothelial barrier antigen between the pial and cortical microvessels of the rat. Brain Res. 744 (1997) 335-338
12. Ciriello J., Hrycyshyn A.W., and Calaresu F.R. Glossopharyngeal and vagal afferent projections to the brain stem of the cat: a horseradish peroxidase study. J. Auton. Nerv. Syst. 4 (1981) 63-79
13. Davies R.O., and Kalia M. Carotid sinus nerve projections to the brain stem in the cat. Brain Res. Bull. 6 (1981) 531-541
14. Ehrlich P. Über die methylenblaureaktion der lebenden Nervensubstans. In: Himmelweit F. (Ed). The Collected Papers of Paul Ehrlich (1956), Pergamon Press, London 500-508
15. Ellacott K.L., Halatchev I.G., and Cone R.D. Characterization of leptin-responsive neurons in the caudal brainstem. Endocrinology 147 (2006) 3190-3195
16. Faouzi M., Leshan R., Björnholm M., Hennessey T., Jones J., and Münzberg H. Differential accessibility of circulating leptin to individual hypothalamic sites. Endocrinology 148 (2007) 5414-5423
17. Fry M., Hoyda T.D., and Ferguson A.V. Making sense of it: roles of the sensory circumventricular organs in feeding and regulation of energy homeostasis. Exp. Biol. Med. 232 (2007) 14-26
18. Gerhart D.Z., LeVasseur R.J., Broderius M.A., and Drewes L.R. Glucose transporter localization in brain using light and electron immunocytochemistry. J. Neurosci. Res. 22 (1989) 464-472
19. Grill H.J. Distributed neural control of energy balance: contributions from hindbrain and hypothalamus. Obesity 5 (2006) 216S-221S
20. Gross P.M., Wall K.M., Pang J.J., Shaver S.W., and Wainman D.S. Microvascular specializations promoting rapid interstitial solute dispersion in nucleus tractus solitarius. Am. J. Physiol. 259 (1990) 1131-1138
21. Harik S.I., Kalaria R.N., Andersson L., Lundahl P., and Perry G. Immunocytochemical localization of the erythroid glucose transporter: abundance in tissues with barrier functions. J. Neurosci. 12 (1990) 3862-3872
22. Harik S.I., and Roessmann U. The erythrocyte-type glucose transporter in blood vessels of primary and metastatic brain tumors. Ann. Neurol. 29 (1991) 487-491
23. Harik S.I., Hall A.K., Richey P., Andersson L., Lundahl P., and Perry G. Ontogeny of the erythroid/HepG2-type glucose transporter (GLUT-1) in the rat nervous system. Brain. Res. Dev. 72 (1993) 41-49
24. Hofman, Hoyng P., van der Werf F., Vrensen G.F., and Schlingemann R.O. Lack of blood-brain barrier properties in microvessels of the prelaminar optic nerve head. Invest. Ophthalmol. Vis. Sci. 42 (2001) 895-901
25. Holash J.A., Harik S.I., Perry G., and Stewart P.A. Barrier properties of testis microvessels. Proc. Natl. Acad. Sci. USA 90 (1993) 11069-11073
26. Hurwitz A.A., Berman J.W., Rashbaum W.K., and Lyman W.D. Human fetal astrocytes induce the expression of blood-brain barrier specific proteins by autologous endothelial cells. Brain Res. 625 (1993) 238-243
27. Jefferies W.A., Brandon M.R., Hunt S.V., Williams A.F., Gatters K.C., and Mason D.Y. Transferrin receptor on endothelium of brain capillaries. Nature 312 (1984) 162-163
28. Kalia M., and Mesulam M.M. Brain stem projections of sensory and motor components of the vagus complex in the cat: II. Laryngeal, tracheobronchial, pulmonary, cardiac, and gastrointestinal branches. J. Comp. Neurol. 193 (1980) 467-508
29. Leslie R.A. Comparative aspects of the area postrema: fine-structural considerations help to determine its function. Cell Mol. Neurobiol. 6 (1986) 95-120
30. Lawrenson J.G., Ghabriel M.N., Reid A.R., Gajree T.N., and Allt G. Differential expression of an endothelial barrier antigen between the CNS and the PNS. J. Anat. 186 (1995) 217-221
31. Lutz T.A., Mollet A., and Rushing P.A. The anorectic effect of a chronic peripheral infusion of amylin is abolished in area postrema/nucleus of the solitary tract (AP/NTS) lesioned rats. Int. J. Obes. Relat. Metab. Disord. 25 (2001) 005-1011
32. McKinley M.J., McAllen R.M., Davern P., Giles M.E., Penschow J., Sunn N., Uschakov A., and Oldfield B.J. The sensory circumventricular organs of the mammalian brain. Adv. Anat. Embryol. Cell Biol. 172 (2003) 1-122
33. Miller A.D., and Nonaka S. Mechanisms of vomiting induced by serotonin-3 receptor agonists in the cat: effect of vagotomy, splanchnicectomy or area postrema lesion. J. Pharmacol. Exp. Ther. 260 (1992) 509-517
34. Miller A.D., and Leslie R.A. The area postrema and vomiting. Front Neuroendocrinol. 15 (1994) 301-320
35. Norsted E., Gömüç B., and Meister B. Protein components of the blood-brain barrier (BBB) in the mediobasal hypothalamus. J. Chem. Neuroanat. 36 (2008) 107-112
36. Orte J.G., Lawrenson T.M., Finn A.R.R., and Allt G. A comparison of blood-brain barrier and blood-nerve barrier endothelial cell markers. Anat. Embryol. (Berl). 199 (1999) 509-517
37. Pan W., and Kastin A.J. Adipokines and the blood-brain barrier. Peptides 28 (2007) 1317-1330
38. Pardridge W.M., Boado R.J., and Farrell C.R. Brain-type glucose transporter (GLUT-1) is selectively localized to the blood-brain barrier. J. Biol. Chem. 265 (1990) 18035-18040
39. Price C.J., Hoyda T.D., and Ferguson A.V. The area postrema: a brain monitor and integrator of systemic autonomic state. Neuroscientist 14 (2008) 182-194
40. Rennels M.L., Gregory T.F., Blaumanis O.R., Fujimoto K., and Grady P.A. Evidence for a 'paravascular' fluid circulation in the mammalian central nervous system, provided by the rapid distribution of tracer protein throughout the brain from the subarachnoid space. Brain Res. 326 (1985) 47-63
41. Rosenstein J.M., Krum J.M., Sternberger L.A., Pulley M.T., and Sternberger N.H. Immunocytochemical expression of the endothelial barrier antigen (EBA) during brain angiogenesis. Brain Res. Dev. 66 (1992) 47-54
42. Saito R., Takano Y., and Kamiya H.O. Roles of substance P and NK(1) receptor in the brainstem in the development of emesis. J. Pharmacol. Sci. 91 (2003) 87-94
43. Shapiro R.E., and Miselis R.R. The central neural connections of the area postrema of the rat. J. Comp. Neurol. 15 (1985) 344-364
44. Schwartz M.W., Baskin D.G., Bukowski T.R., Kuijper J.L., Foster D., Lasser G., Prunkard D.E., Porte Jr. D., Woods S.C., Seeley R.J., and Weigle D.S. Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes 45 (1996) 531-535
45. Schwartz M.W., Woods S.C., Porte Jr. D., Seeley R.J., and Baskin D.G. Central nervous system control of food intake. Nature 404 (2000) 661-671
46. Stephens T.W., Basinski M., Bristow P.K., Bue-Valleskey J.M., Burgett S.G., Craft L., Hale J., Hoffmann J., Hsiung H.M., Kriauciunas A., Mackellar Q., Rosteck Jr. P.R., Schoner B., Smith D., Tinsley F.C., Zhang X.-Y., and Heiman M. The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 377 (1995) 530-532
47. Sternberger N.H., Sternberger L.A., Kies M.W., and Shear C.R. Cell surface endothelial proteins altered in experimental allergic encephalomyelitis. J. Neuroimmunol. 21 (1989) 241-248
48. Sternberger N.H., and Sternberger L.A. Blood-brain barrier protein recognized by monoclonal antibody. Proc. Natl. Acad. Sci. USA 84 (1987) 8169-8173
49. Takata K., Kasahara T., Kasahara M., Ezaki O., and Hirano H. Erythrocyte/HepG2-type glucose transporter is concentrated in cells of blood-tissue barriers. Biochem. Biophys. Res. Commun. 173 (1990) 67-73
50. Vigier D., and Portalier P. Efferent projections of the area postrema demonstrated by autoradiography. Arch. Ital. Biol. 117 (1979) 308-324
51. Wang Q.P., Guan J.L., Pan W., Kastin A.J., and Shioda S. A diffusion barrier between the area postrema and nucleus tractus solitarius. Neurochem. Res. 33 (2008) 2035-2043
52. Willis C.L., Garwood C.J., and Ray D.E. A size selective vascular barrier in the rat area postrema formed by perivascular macrophages and the extracellular matrix. Neuroscience 150 (2007) 498-509
53. Willesen M.G., Kristensen P., and Romer J. Co-localization of growth hormone secretagogue receptor and NPY mRNA in the arcuate nucleus of the rat. Neuroendocrinology 70 (1999) 306-316
54. Young J.K., and Wang C. Glucose transporter immunoreactivity in the hypothalamus and the area postrema. Brain Res. Bull. 24 (1990) 525-528
55. Zeller K., Rahner-Welsch S., and Kuschinsky W. Distribution of Glut1 glucose transporters in different brain structures compared to glucose utilization and capillary density of adult rat brains. J. Cereb. Blood Flow Metab. 17 (1997) 204-209
56. Zigman J.M., Jones J.E., Lee C.E., Saper C.B., and Elmquist J.K. Expression of ghrelin receptor mRNA in the rat and the mouse brain. J. Comp. Neurol. 494 (2006) 528-548