In vivo measurement of hippocampal GABAa/cBZR density with [18F]-flumazenil PET for the study of disease progression in an animal model of temporal lobe epilepsy

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Vivash, Lucy ^a   Gregoire, Marie Claude ^b   Bouilleret, Viviane ^a   Berard, Alexis ^b   Wimberley, Catriona ^b   Binns, David ^c   Roselt, Peter ^c   Katsifis, Andrew ^b   Myers, Damian E ^a   Hicks, Rodney J ^c   O'Brien, Terence J ^a   Dedeurwaerdere, Stefanie ^a,d  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

^c PETER MACCALLUM CANCER CENTRE   (Australia)

^d UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE RECEPTOR; FLUMAZENIL; FLUMAZENIL F 18; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BLOOD SAMPLING; BRAIN SIZE; CELL LOSS; CONTROLLED STUDY; DISEASE COURSE; ELECTROENCEPHALOGRAM; EPILEPTIC STATE; GABAERGIC TRANSMISSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; HISTOPATHOLOGY; IMAGE ANALYSIS; IN VIVO STUDY; MALE; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; RECEPTOR BINDING; TEMPORAL LOBE EPILEPSY;

ANIMALS; DISEASE PROGRESSION; EPILEPSY, TEMPORAL LOBE; FLUMAZENIL; HIPPOCAMPUS; MALE; MODELS, ANIMAL; RATS; RATS, WISTAR; RECEPTORS, GABA-A; SYNAPTIC TRANSMISSION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 84901665976     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086722     Document Type: Article

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