Kinetic modelling of [11C]flumazenil using data-driven methods

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 36, Issue 4, 2009, Pages 659-670

  Miederer, Isabelle ^a   Ziegler, Sibylle I ^a   Liedtke, Christoph ^a   Spilker, Mary E ^b   Miederer, Matthias ^a   Sprenger, Till ^a   Wagner, Klaus J ^a   Drzezga, Alexander ^a   Boecker, Henning ^c  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b GE GLOBAL RESEARCH   (United States)

^c UNIVERSITY OF BONN   (Germany)

Author keywords

11C Flumazenil; Benzodiazepine receptors; Parametric images; PET; Pharmacokinetics 18F labelled; Reference tissue methods

Indexed keywords

FLUMAZENIL C 11; 4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE RECEPTOR AFFECTING AGENT; FLUMAZENIL; FLUORODEOXYGLUCOSE F 18; RADIOPHARMACEUTICAL AGENT;

ARTERIAL BLOOD; ARTICLE; BLOOD SAMPLING; BRAIN REGION; COMPARTMENT MODEL; CONTROLLED STUDY; DISTRIBUTION VOLUME; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; SPECTROSCOPY; BRAIN; CHEMISTRY; KINETICS; METHODOLOGY; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; SCINTISCANNING; TIME;

BRAIN; CHEMISTRY, PHARMACEUTICAL; FEMALE; FLUMAZENIL; FLUORODEOXYGLUCOSE F18; GABA MODULATORS; HUMANS; KINETICS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RECEPTORS, GABA-A; TIME FACTORS;

EID: 62149086304     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-008-0990-z     Document Type: Article

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