Clinical utility of flumazenil-PET versus [18F]fluorodeoxyglucose-PET and MRI in refractory partial epilepsy. A prospective study in 100 patients

Brain

Volumn 121, Issue 11, 1998, Pages 2067-2081

  Ryvlin, P ^a,b   Bouvard, S ^a   Le Bars, D ^a   De Lamerie G ^a   Gregoire M C ^a   Kahane, P ^a   Froment, J C ^b   Mauguiere F ^a  

^a GRENOBLE UNIVERSITY HOSPITAL   (France)

^b HÔPITAL NEUROLOGIQUE   (France)

Author keywords

Benzodiazepine receptors; Epilepsy; Flumazenil; PET

Indexed keywords

FLUMAZENIL; FLUORODEOXYGLUCOSE F 18;

ARTICLE; CLINICAL TRIAL; ELECTROENCEPHALOGRAM; FEMALE; FOCAL EPILEPSY; FRONTAL LOBE EPILEPSY; GLUCOSE METABOLISM; HIPPOCAMPUS; HUMAN; IMAGING SYSTEM; MAJOR CLINICAL STUDY; MALE; META ANALYSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PHOTON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROSPECTIVE STUDY; SEIZURE; SURGICAL APPROACH; TECHNIQUE; TEMPORAL LOBE EPILEPSY;

EID: 0031768637     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/121.11.2067     Document Type: Article

References (33)

1. Arruda F, Cendes F, Andermann F, Dubeau F, Villemure JG, Jones-Gotman M, et al. Mesial atrophy and outcome after amygdalohippocampectomy or temporal lobe removal. Ann Neurol 1996; 40: 446-50.
2. Bancaud J, Chauvel P. Commentary: acute and chronic intracranial recording and stimulation with depth electrodes. In: Engel J Jr, editor. Surgical treatment of the epilepsies. New York: Raven Press; 1987. p. 289-96.
3. Ben Attia M, N'Gouemo P, Belaidi M, Rondouin G, Chicheportiche R. Kindling and electrode effects on the benzodiazepine receptors density of olfactory bulb and hippocampus after olfactory bulb kindling. Neurosci Lett 1992; 143: 74-8.
4. Burdette DE, Sakurai SY, Henry TR, Ross DA, Pennell PB, Frey KA, et al. Temporal lobe central benzodiazepine binding in unilateral mesial temporal lobe epilepsy. Neurology 1995; 45: 934-41.
5. Cinotti L, Froment JC, Peyron R, Ryvlin P, Le Bars D, Mauguière F. Optimisation des images hippocampiques de captation glucidique par tomographie D'émission de positons dans L'épilepsie du lobe temporal. Méd Nucl 1996; 20: 70-6.
6. 123I-iomazenil SPECT in presurgical evaluation of temporal lobe epilepsy? J Neurol Neurosurg Psychiatry 1997; 62: 141-50.
7. Henry TR, Frey KA, Sackellares JC, Oilman S, Koeppe RA, Brunberg JA, et al. In vivo cerebral metabolism and central benzodiazepine-receptor binding in temporal lobe epilepsy. Neurology 1993; 43: 1998-2006.
8. Koepp MJ, Richardson MP, Brooks DJ, Poline JB, Van Paesschen W, Friston KJ, et al. Cerebral benzodiazepine receptors in hippocampal sclerosis: an objective in vivo analysis. Brain 1996; 119: 1677-87.
9. Koepp MJ, Richardson MP, Labbé C, Brooks DJ, Cunningham VJ, Ashburner J, et al. 11C-flumazenil PET, volumetric MRI, and quantitative pathology in mesial temporal lobe epilepsy. Neurology 1997; 49: 764-73.
10. Loring DW, Lee GP, Meador KJ, Flanigin HF, Smith JR, Figueroa RE. The intracarotid amobarbital procedure as a predictor of memory failure following unilateral temporal lobectomy. Neurology 1990; 40: 605-10.
11. McNamara JO, Peper AM, Patrone V. Repeated seizures induce long-term increase in hippocampal benzodiazepine receptors. Proc Natl Acad Sci USA 1980; 77: 3029-32.
12. Millet P, Delforge J, Mauguiere F, Pappata S, Cinotti L, Frouin V, et al. Parameter and index images of benzodiazepine receptor concentration in the brain. J Nucl Med 1995; 36: 1462-71.
13. Munari C, Bancaud J. The role of stereo-electroencephalography (SEEG) in the evaluation of partial epileptic seizures. In: Porter RJ, Morselli PL, editors. The epilepsies. London: Butterworths; 1985. p. 267-306.
14. Musolino A, Tournoux P, Missir O, Talairach J. Methodology of 'in vivo' anatomical study and stereo-electroencephalographic exploration in brain surgery for epilepsy. J Neuroradiol 1990; 17: 67-102.
15. Nobrega JN, Kish SJ, Burnham WM. Autoradiographic analysis of benzodiazepine binding in entorhinal-kindled rat brains. Brain Res 1989; 498: 315-22.
16. Richardson MP, Koepp MJ, Brooks DJ, Fish DR, Duncan JS. Benzodiazepine receptors in focal epilepsy with cortical dysgenesis: an 11C-flumazenil PET study. Ann Neurol 1996; 40: 188-98.
17. Ryvlin P, Cinotti L, Froment JC, Le Bars D, Landais P, Chaze M, et al. Metabolic patterns associated with non-specific magnetic resonance imaging abnormalities in temporal lobe epilepsy. Brain 1991; 114: 2363-83.
18. Ryvlin P, Philippon B, Cinotti L, Froment JC, Le Bars D, Mauguière F. Functional neuroimaging strategy in temporal lobe epilepsy: a comparative study of 18FDG-PET and 99mTc-HMPAO-SPECT. Ann Neurol 1992; 31: 650-6.
19. Ryvlin P, Mauguière F, Sindou M, Froment JC, Cinotti L. Interictal cerebral metabolism and epilepsy in cavernous angiomas. Brain 1995; 118: 677-87.
20. Ryvlin P, Veyre L, Le Bars D, Comar D, Lavenne F, Mauguière F. False lateralization of 11C-flumazenil PET findings in temporal lobe epilepsy [abstract]. Epilepsia 1996; 37 Suppl 5: 207.
21. Ryvlin P, Guénot M, Isnard J, Sindou M, Comar D, Froment JC, et al. The role of the temporopolar cortex in temporal lobe epilepsy [abstract]. Stereotact Funct Neurosurg 1997; 67: 143.
22. Savic I, Persson A, Roland P, Pauli S, Sedvall G, Widen L. In-vivo demonstration of reduced benzodiazepine receptor binding in human epileptic foci. Lancet 1988; 2: 863-6.
23. Savic I, Ingvar M, Stone-Elander S. Comparison of [11C]flumazenil and [18F]FDG as PET markers of epileptic foci. J Neurol Neurosurg Psychiatry 1993; 56: 615-21.
24. Savic I, Thorell JO, Roland P. [11C]flumazenil positron emission tomography visualizes frontal epileptogenic regions. Epilepsia 1995; 36: 1225-32.
25. Savic I, Svanborg E, Thorell JO. Cortical benzodiazepine receptor changes are related to frequency of partial seizures: a positron emission tomography study. Epilepsia 1996; 37: 236-44.
26. 11C]flumazenil binding after epilepsy surgery. Acta Neurol Scand 1998; 97: 279-86.
27. Semah F, Baulac M, Hasboun D, Frouin V, Mangin JF, Papageorgiou S, et al. Is interictal temporal hypo metabolism related to mesial temporal sclerosis? A positron emission tomography/magnetic resonance imaging confrontation. Epilepsia 1995; 36: 447-56.
28. Shin C, Pedersen HB, McNamara JO. Gamma-aminobutyric acid and benzodiazepine receptors in the kindling model of epilepsy: a quantitative radiohistochemical study. J Neurosci 1985; 5: 2696-701.
29. Swartz BW, Khonsari A, Brown C, Mandelkern M, Simpkins F, Krisdakumtorn T. Improved sensitivity of (18)FDG-positron emission tomography scans in frontal and 'frontal plus' epilepsy. Epilepsia 1995; 36: 388-95.
30. Szelies B, Weber-Luxenburger G, Pawlik G, Kessler J, Holthoff V, Mielke R, et al. MRI-guided flumazenil- and FDG-PET in temporal lobe epilepsy. Neuroimage 1996; 3: 109-18.
31. Talairach J, Bancaud J, Szikla G, Bonis A, Geier S, Vedrenne C. Approche nouvelle de la neurochirurgie de l'épilepsie. Méthodologie stéréotaxique et résultats thérapeutiques. I. Introduction et historique. Neurochirurgie 1974; 20: 1-240.
32. Valdes F, Dasheiff RM, Birmingham F, Crutcher KA, McNamara JO. Benzodiazepine receptor increases after repeated seizures: Evidence for localization to dentate granule cells. Proc Natl Acad Sci USA 1982; 79: 193-7.
33. Wieser HG, Moser S. Improved multipolar foramen ovale electrode monitoring. J Epilepsy 1988; 1: 13-22.