Mutually exclusive mutations of KIT and RAS are associated with KIT mRNA expression and chromosomal instability in primary intracranial pure germinomas

Acta Neuropathologica

Volumn 127, Issue 6, 2014, Pages 911-925

  Fukushima, Shintaro ^a   Otsuka, Ayaka ^a   Suzuki, Tomonari ^b   Yanagisawa, Takaaki ^b   Mishima, Kazuhiko ^b   Mukasa, Akitake ^c   Saito, Nobuhito ^c   Kumabe, Toshihiro ^e   Kanamori, Masayuki ^d   Tominaga, Teiji ^d   Narita, Yoshitaka ^f   Shibui, Soichiro ^f   Kato, Mamoru ^a   Shibata, Tatsuhiro ^a   Matsutani, Masao ^b   Nishikawa, Ryo ^b   Ichimura, Koichi ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b SAITAMA MEDICAL UNIVERSITY INTERNATIONAL MEDICAL CENTER   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e KITASATO UNIVERSITY   (Japan)

^f NATIONAL CANCER CENTER HOSPITAL   (Japan)

Author keywords

Chromosomal instability; Intracranial germ cell tumors; KIT mRNA expression; KIT mutation; RAS mutation

Indexed keywords

MESSENGER RNA;

ADOLESCENT; ADULT; ARTICLE; CHILD; CHORIOCARCINOMA; CHROMOSOMAL INSTABILITY; COMPARATIVE GENOMIC HYBRIDIZATION; FEMALE; GERM CELL TUMOR; HUMAN; HUMAN TISSUE; INFANT; INTRACRANIAL TUMOR; MAJOR CLINICAL STUDY; MALE; ONCOGENE; ONCOGENE KIT; ONCOGENE RAS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOMATIC MUTATION; TERATOMA; YOLK SAC TUMOR;

EID: 84901650709     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-014-1247-5     Document Type: Article

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