Rapid Evolution of PARP Genes Suggests a Broad Role for ADP-Ribosylation in Host-Virus Conflicts

PLoS Genetics

Volumn 10, Issue 5, 2014, Pages

  Daugherty, Matthew D ^a   Young, Janet M ^a   Kerns, Julie A ^a,b   Malik, Harmit S ^a,c  

^a USA   (United States)

^b INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP15 PROTEIN, HUMAN; POLY(ADP-RIBOSE) POLYMERASE FAMILY MEMBER 14, HUMAN;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ARTICLE; EVOLUTION; GENE; GENE LOSS; GENETIC GAIN; GENETIC SELECTION; NUCLEOTIDE SEQUENCE; PARP GENE; PARP14 GENE; PARP15 GENE; PARP4 GENE; PARP9 GENE; POSITIVE SELECTION; VIRUS CELL INTERACTION; GENETICS; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MOLECULAR EVOLUTION; PATHOGENICITY; PROTEIN PROCESSING; VIRUS;

ADENOSINE DIPHOSPHATE RIBOSE; ADP RIBOSE TRANSFERASES; EVOLUTION, MOLECULAR; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; VIRUSES;

EID: 84901594799     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004403     Document Type: Article

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