The vault complex

Cellular and Molecular Life Sciences

Volumn 60, Issue 9, 2003, Pages 1828-1837

  Van Zon, A ^a   Mossink, M H ^a   Scheper, R J ^b   Sonneveld, P ^a   Wiemer, E A C ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

MVP; TEP1; Vaults; VPARP; vRNA

Indexed keywords

DNA; LUNG RESISTANCE PROTEIN; RIBONUCLEOPROTEIN; TELOMERASE;

CELLULAR DISTRIBUTION; DNA REPLICATION; DNA SEQUENCE; DNA STRUCTURE; ENZYME ACTIVITY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOCATION; MOLECULAR CLONING; MOLECULAR WEIGHT; MULTIDRUG RESISTANCE; NONHUMAN; ORTHOLOGY; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; RNA BINDING; RNA DEGRADATION;

ANIMALS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CYTOSKELETON; DRUG RESISTANCE, MULTIPLE; HUMANS; POLY(ADP-RIBOSE) POLYMERASES; RNA; VAULT RIBONUCLEOPROTEIN PARTICLES;

EUKARYOTA;

EID: 0141526367     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-003-3030-y     Document Type: Review

References (73)

1. Kedersha N. L. and Rome L. H. (1986) Isolation and characterization of a novel ribonucleoprotein particle: large structures contain a single species of small RNA. J. Cell Biol. 103: 699-709
2. Kedersha N. L., Miquel M. C., Bittner D. and Rome L. H. (1990) Vaults. II. Ribonucleoprotein structures are highly conserved among higher and lower eukaryotes. J. Cell Biol. 110: 895-901
3. Kong L. B., Siva A. C., Rome L. H. and Stewart P. L. (1999) Structure of the vault, a ubiquitous cellular component. Structure Fold. Des. 7:371-379
4. Batey R. T., Rambo R. P., Lucast L., Rha B. and Doudna J. A. (2000) Crystal structure of the ribonucleoprotein core of the signal recognition particle. Science 287: 1232-1239
5. Rome L., Kedersha N. and Chugani D. (1991) Unlocking vaults: organelles in search of a function. Trends Cell Biol. 1: 47-50
6. Kickhoefer V. A., Vasu S. K. and Rome L. H. (1996) Vaults are the answer, what is the question? Trends Cell Biol. 6: 174-178
7. Kickhoefer V. A., Siva A. C., Kedersha N. L., Inman E. M., Ruland C., Streuli M. et al. (1999) The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase. J. Cell Biol. 146: 917-928
8. Kickhoefer V. A., Stephen A. G., Harrington L., Robinson M. O. and Rome L. H. (1999) Vaults and telomerase share a common subunit, TEP1. J. Biol. Chem. 274: 32712-32717
9. Kong L. B., Siva A. C., Kickhoefer V. A., Rome L. H. and Stewart P. L. (2000) RNA location and modeling of a WD40 repeat domain within the vault. RNA 6: 890-900
10. Kedersha N. L., Heuser J. E., Chugani D. C. and Rome L. H. (1991) Vaults. III. Vault ribonucleoprotein particles open into flower-like structures with octagonal symmetry. J. Cell Biol. 112: 225-235
11. Vasu S. K., Kedersha N. L. and Rome L. H. (1993) cDNA cloning and disruption of the major vault protein alpha gene (mvpA) in Dictyostelium discoideum. J. Biol. Chem. 268: 15356-15360
12. Kickhoefer V. A. and Rome L. H. (1994) The sequence of a cDNA encoding the major vault protein from Rattus norvegicus. Gene 151: 257-260
13. Vasu S. K. and Rome L. H. (1995) Dictyostelium vaults: disruption of the major proteins reveals growth and morphological defects and uncovers a new associated protein. J. Biol. Chem. 270: 16588-16594
14. Herrmann C., Zimmermann H. and Volknandt W. (1997) Analysis of a cDNA encoding the major vault protein from the electric ray Discopyge ommata. Gene 188: 85-90
15. Mossink M., van Zon A., Franzel-Luiten E., Schoester M., Scheffer G., Scheper R. et al. (2002) The genomic sequence of the murine major vault protein and its promoter. Gene 294: 225
16. Slovak M. L., Ho J. P., Cole S. P., Deeley R. G., Greenberger L., de Vries E. G. et al. (1995) The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: evidence that chromosome breakage plays a key role in MRP or LRP gene amplification. Cancer Res. 55: 4214-4219
17. Lange C., Walther W., Schwabe H. and Stein U. (2000) Cloning and initial analysis of the human multidrug resistance-related MVP/LRP gene promoter. Biochem. Biophys. Res. Commun. 278: 125-133
18. Holzmann K, Ambrosch I, Elbling L., Micksche M., Berger W. (2001) A small upstream open reading frame causes inhibition of human major vault protein expression from a ubiquitous mRNA splice variant. FEBS Lett. 494: 99-104
19. Herrmann C., Kellner R. and Volknandt W. (1998) Major vault protein of electric ray is a phosphoprotein. Neurochem. Res. 23: 39-46
20. van Zon A., Mossink M. H., Schoester M, Scheffer G. L., Scheper R. J., Sonneveld P. et al. (2002) Structural domains of vault proteins: a role for the coiled coil domain in vault assembly. Biochem. Biophys. Res. Commun. 291: 535-541
21. Moncrief N. D., Kretsinger R. H. and Goodman M. (1990) Evolution of EF-hand calcium-modulated proteins. I. Relationships based on amino acid sequences. J. Mol. Evol. 30: 522-562
22. Yu Z., Fotouhi-Aroakani N., Wu L., Maoui M, Wang S., Banville D. et al. (2002) PTEN Associates with the vault particles in Hela cells. J. Biol. Chem. 11: 11
23. Schroeijers A. B., Siva A. C., Scheffer G. L., de Jong M. C., Bolick S. C., Dukers D. F. et al. (2000) The Mr 193,000 vault protein is up-regulated in multidrug-resistant cancer cell lines. Cancer Res. 60: 1104-1110
24. Still I. H., Vince P. and Cowell J. K. (1999) Identification of a novel gene (ADPRTL1) encoding a potential Poly(ADP-ribosyl)transferase protein. Genomics 62: 533-536
25. Jean L., Risler J. L., Nagase T., Coulouarn C., Nomura N. and Salier J. P. (1999) The nuclear protein PH5P of the inter-alpha-inhibitor superfamily: a missing link between poly(ADP-ribose)polymerase and the inter-alpha-inhibitor family and a novel actor of DNA repair? FEBS Lett. 446: 6-8
26. Smith S. (2001) The world according to PARP. Trends Biochem. Sci. 26: 174-179
27. Shall S. (2002) Poly (ADP-ribosylation) - a common control process? Bioessays 24: 197-201
28. de Murcia G. and Menissier de Murcia J. (1994) Poly(ADP-ribose) polymerase: a molecular nick-sensor. Trends Biochem. Sci. 19: 172-176
29. D'Amours D., Desnoyers S., D'Silva I. and Poirier G. G. (1999) Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem. J. 342:249-268
30. Callebaut I. and Mornon J. P. (1997) From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair. FEBS Lett. 400: 25-30
31. Koonin E. V., Altschul S. F. and Bork P. (1996) BRCA1 protein products ⋯ Functional motifs ⋯ [letter]. Nat. Genet. 13: 266-268
32. Bork P., Hofmann K., Bucher P., Neuwald A. F., Altschul S. F. and Koonin E. V. (1997) A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins. FASEB J. 11: 68-76
33. Zhang X., Morera S., Bates P. A., Whitehead P. C., Coffer A. I., Hainbucher K. et al. (1998) Structure of an XRCC1 BRCT domain: a new protein-protein interaction module. EMBO J. 17: 6404-6411
34. Salier J. P., Rouet P., Raguenez G. and Daveau M. (1996) The inter-alpha-inhibitor family: from structure to regulation. Biochem. J. 315: 1-9
35. Bork P. and Rohde K. (1991) More von Willebrand factor type A domains? Sequence similarities with malaria thrombospondin-related anonymous protein, dihydropyridine- sensitive calcium channel and inter-alpha-trypsin inhibitor. Biochem. J. 279: 908-910
36. Harrington L., McPhail T., Mar V., Zhou W., Oulton R., Bass M. B. et al. (1997) A mammalian telomerase-associated protein [see comments]. Science 275: 973-977
37. Nakayama J., Saito M., Nakamura H., Matsuura A. and Ishikawa F. (1997) TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family. Cell 88: 875-884
38. Beattie T. L., Zhou W., Robinson M. O. and Harrington L. (2000) Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding. Mol. Biol. Cell. 11: 3329-3340
39. Weinrich S. L., Pruzan R., Ma L., Ouellette M., Tesmer V. M., Holt S. E. et al. (1997) Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT. Nat. Genet. 17: 498-502
40. Koyanagi Y., Kobayashi D., Yajima T., Asanuma K., Kimura T., Sato T. et al. (2000) Telomerase activity is down regulated via decreases in hTERT mRNA but not TEP1 mRNA or hTERC during the differentiation of leukemic cells. Anticancer Res. 20: 773-778
41. Liu Y., Snow B. E., Hande M. P., Baerlocher G., Kickhoefer V. A., Yeung D. et al. (2000) Telomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivo. Mol. Cell. Biol. 20: 8178-8184
42. Saito T, Matsuda Y., Suzuki T., Hayashi A. Yuan X., Saito M. et al. (1997) Comparative gene mapping of the human and mouse TEP1 genes, which encode one protein component of telomerases. Genomics 46: 46-50
43. Neer E. J., Schmidt C. J., Nambudripad R. and Smith T. F. (1994) The ancient regulatory-protein family of WD-repeat proteins [published erratum appears in Nature 1994 Oct 27;371(6500):812]. Nature 371: 297-300
44. Smith T. F., Gaitatzes C., Saxena K. and Neer E. J. (1999) The WD repeat: a common architecture for diverse functions. Trends Biochem. Sci. 24: 181-185
45. Kickhoefer V. A., Searles R. P., Kedersha N. L., Garber M. E., Johnson D. L. and Rome L. H. (1993) Vault ribonucleoprotein particles from rat and bullfrog contain a related small RNA that is transcribed by RNA polymerase III. J. Biol. Chem. 268: 7868-7873
46. van Zon A., Mossink M. H., Schoester M., Scheffer G. L., Scheper R. J., Sonneveld P. et al. (2001) Multiple human vault RNAs. Expression and association with the vault complex. J. Biol. Chem. 276: 37715-37721
47. Stewart P. L., Chiu C. Y., Haley D. A., Kong L. B. and Schlessman J. L. (1999) Review: resolution issues in single-particle reconstruction. J. Struct. Biol. 128: 58-64
48. Kickhoefer V. A., Liu Y, Kong L. B., Snow B. E., Stewart P. L., Harrington L. et al. (2001) The telomerase/vault-associated protein TEP1 is required for vault RNA stability and its association with the vault particle. J. Cell Biol. 152: 157-164
49. Stephen A. G., Raval-Fernandes S., Huynh T., Torres M., Kickhoefer V. A. and Rome L. H. (2001) Assembly of vault-like particles in insect cells expressing only the major vault protein. J. Biol. Chem. 276: 23217-23220
50. Kickhoefer V. A., Rajavel K. S., Scheffer G. L., Dalton W. S., Scheper R. J. and Rome L. H. (1998) Vaults are up-regulated in multidrug-resistant cancer cell lines. J. Biol. Chem. 273: 8971-8974
51. Kedersha N. L. and Rome L. H. (1990) Vaults: large cytoplasmic RNP's that associate with cytoskeletal elements. Mol. Biol. Rep. 14: 121-122
52. Herrmann C., Golkaramnay E., Inman E., Rome L. and Volknandt W. (1999) Recombinant major vault protein is targeted to neuritic tips of PC12 cells. J. Cell Biol. 144: 1163-1172
53. Hamill D. R. and Suprenant K. A. (1997) Characterization of the sea urchin major vault protein: a possible role for vault ribonucleoprotein particles in nucleocytoplasmic transport. Dev. Biol. 190: 117-128
54. Berger W., Elbling L. and Micksche M. (2000) Expression of the major vault protein LRP in human non-small-cell lung cancer cells: activation by short-term exposure to antineoplastic drugs. Int. J. Cancer. 88: 293-300
55. Chugani D. C., Rome L. H. and Kedersha N. L. (1993) Evidence that vault ribonucleoprotein particles localize to the nuclear pore complex. J. Cell Sci. 106: 23-29
56. Abbondanza C., Rossi V., Roscigno A., Gallo L., Belsito A., Piluso G. et al. (1998) Interaction of vault particles with estrogen receptor in the MCF-7 breast cancer cell. J. Cell Biol. 141: 1301-1310
57. Li J. Y., Volknandt W., Dahlstrom A., Herrmann C., Blasi J., Das B. and Zimmermann H. (1999) Axonal transport of ribonucle-oprotein particles (vaults). Neuroscience 91: 1055-1065
58. Herrmann C., Volknandt W., Wittich B., Kellner R. and Zimmermann H. (1996) The major vault protein (MVP100) is contained in cholinergic nerve terminals of electric ray electric organ. J. Biol. Chem. 271: 13908-13915
59. Stoffler D., Fahrenkrog B. and Aebi U. (1999) The nuclear pore complex: from molecular architecture to functional dynamics. Curr. Opin. Cell Biol. 11: 391-401
60. Scheffer G. L., Wijngaard P. L., Flens M. J., Izquierdo M. A., Slovak M. L., Pinedo H. M. et al. (1995) The drug resistance-related protein LRP is the human major vault protein. Nat. Med. 1: 578-582
61. Scheper R. J., Broxterman H. J., Scheffer G. L., Kaaijk P., Dalton W. S., van Heijningen T. H. et al. (1993) Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance. Cancer Res. 53: 1475-1479
62. Siva A. C., Raval-Fernandes S., Stephen A. G., LaFemina M. J., Scheper R. J., Kickhoefer V. A. et al. (2001) Up-regulation of vaults may be necessary but not sufficient for multidrug resistance. Int. J. Cancer 92: 195-202
63. Izquierdo M. A., Scheffer G. L., Flens M. J., Giaccone G., Broxterman H. J., Meijer C. J. et al. (1996) Broad distribution of the multidrug resistance-related vault lung resistance protein in normal human tissues and tumors. Am. J. Pathol. 148: 877-887
64. Izquierdo M. A., Shoemaker R. H., Flens M. J., Scheffer G. L., Wu L., Prather T. R. et al. (1996) Overlapping phenotypes of multidrug resistance among panels of human cancer-cell lines. Int. J. Cancer 65: 230-237
65. Scheffer G. L., Schroeijers A. B., Izquierdo M. A., Wiemer E. A. and Scheper R. J. (2000) Lung resistance-related protein/major vault protein and vaults in multidrug-resistant cancer. Curr. Opin. Oncol. 12: 550-556
66. Ohno N., Tani A., Uozumi K., Hanada S., Furukawa T., Akiba S. et al. (2001) Expression of functional lung resistance - related protein predicts poor outcome in adult T-cell leukemia. Blood 98: 1160-1165
67. Kitazono M., Okumura H., Ikeda R., Sumizawa T., Furukawa T., Nagayama S. et al. (2001) Reversal of LRP-associated drug resistance in colon carcinoma SW-620 cells. Int. J. Cancer 91: 126-131
68. Kitazono M., Sumizawa T., Takebayashi Y., Chen Z. S., Furukawa T., Nagayama S. et al. (1999) Multidrug resistance and the lung resistance-related protein in human colon carcinoma SW-620 cells [see comments]. J. Natl. Cancer Inst. 91: 1647-1653
69. Mossink M. H., Van Zon A., Franzel-Luiten E., Schoester M., Kickhoefer V. A., Scheffer G. L. et al. (2002) Disruption of the murine major vault protein (MVP/LRP) gene does not induce hypersensitivity to cytostatics. Cancer Res. 62: 7298-7304
70. Schroeijers A. B., Reurs A. W., Scheffer G. L., Stam A. G., de Jong M. C., Rustemeyer T. et al. (2002) Up-regulation of drug resistance-related vaults during dendritic cell development. J. Immunol. 168: 1572-1578
71. Suprenant K. A. (2002) Vault ribonucleoprotein particles: sarcophagi, gondolas or safety deposit boxes? Biochemistry 41: 14447-14454
72. Kickhoefer V. A., Poderycki M. J., Chan E. K. and Rome L. H. (2002) The La RNA binding protein interacts with the vault RNA and is a vault-associated protein. J. Biol. Chem. 23: 23
73. Di Cristofano A., Pesce B., Cordon-Cardo C. and Pandolfi P. P. (1998) Pten is essential for embryonic development and tumour suppression. Nat. Genet. 19: 348-355