-
1
-
-
0001102239
-
Pedigree demonstrating a sex-linked recessive condition characterized by draining ears, eczematoid dermatitis and bloody diarrhea
-
Aldrich, R. A., Steinberg, A. G. and Campbell, D. C. 1954. Pedigree demonstrating a sex-linked recessive condition characterized by draining ears, eczematoid dermatitis and bloody diarrhea. Pediatrics 13:133.
-
(1954)
Pediatrics
, vol.13
, pp. 133
-
-
Aldrich, R.A.1
Steinberg, A.G.2
Campbell, D.C.3
-
2
-
-
0027937223
-
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
-
Derry, J. M., Ochs, H. D. and Francke, U. 1994. Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. Cell 78:635.
-
(1994)
Cell
, vol.78
, pp. 635
-
-
Derry, J.M.1
Ochs, H.D.2
Francke, U.3
-
3
-
-
0029982620
-
Studies of the expression of the Wiskott-Aldrich syndrome protein
-
Stewart, D. M., Treiber-Held, S., Kurman, C. C., Facchetti, F., Notarangelo, L. D. and Nelson, D. L. 1996. Studies of the expression of the Wiskott-Aldrich syndrome protein. J. Clin. Invest. 97:2627.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2627
-
-
Stewart, D.M.1
Treiber-Held, S.2
Kurman, C.C.3
Facchetti, F.4
Notarangelo, L.D.5
Nelson, D.L.6
-
4
-
-
33749343053
-
Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia
-
Ancliff, P. J., Blundell, M. P., Cory, G. O. et al. 2006. Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia. Blood 108:2182.
-
(2006)
Blood
, vol.108
, pp. 2182
-
-
Ancliff, P.J.1
Blundell, M.P.2
Cory, G.O.3
-
5
-
-
0035093787
-
Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia
-
Devriendt, K., Kim, A. S., Mathijs, G. et al. 2001. Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia. Nat. Genet. 27:313.
-
(2001)
Nat. Genet.
, vol.27
, pp. 313
-
-
Devriendt, K.1
Kim, A.S.2
Mathijs, G.3
-
6
-
-
77649153819
-
WASP: a key immunological multitasker
-
Thrasher, A. J. and Burns, S. O. 2010. WASP: a key immunological multitasker. Nat. Rev. Immunol. 10:182.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 182
-
-
Thrasher, A.J.1
Burns, S.O.2
-
7
-
-
0242558357
-
The verprolin-like central (vc) region of Wiskott-Aldrich syndrome protein induces Arp2/3 complexdependent actin nucleation
-
Hüfner, K., Higgs, H. N., Pollard, T. D., Jacobi, C., Aepfelbacher, M. and Linder, S. 2001. The verprolin-like central (vc) region of Wiskott-Aldrich syndrome protein induces Arp2/3 complexdependent actin nucleation. J. Biol. Chem. 276:35761.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35761
-
-
Hüfner, K.1
Higgs, H.N.2
Pollard, T.D.3
Jacobi, C.4
Aepfelbacher, M.5
Linder, S.6
-
8
-
-
0033576288
-
Influence of the C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp2/3 complex on actin polymerization
-
Higgs, H. N., Blanchoin, L. and Pollard, T. D. 1999. Influence of the C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp2/3 complex on actin polymerization. Biochemistry 38:15212.
-
(1999)
Biochemistry
, vol.38
, pp. 15212
-
-
Higgs, H.N.1
Blanchoin, L.2
Pollard, T.D.3
-
9
-
-
9444221962
-
Mechanisms of WASp-mediated hematologic and immunologic disease
-
Burns, S., Cory, G. O., Vainchenker, W. and Thrasher, A. J. 2004. Mechanisms of WASp-mediated hematologic and immunologic disease. Blood 104:3454.
-
(2004)
Blood
, vol.104
, pp. 3454
-
-
Burns, S.1
Cory, G.O.2
Vainchenker, W.3
Thrasher, A.J.4
-
10
-
-
39649094147
-
Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells
-
Bouma, G., Burns, S. and Thrasher, A. J. 2007. Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells. Blood 110:4278.
-
(2007)
Blood
, vol.110
, pp. 4278
-
-
Bouma, G.1
Burns, S.2
Thrasher, A.J.3
-
11
-
-
31544454208
-
WIP and WASP play complementary roles in T cell homing and chemotaxis to SDF-1alpha
-
Gallego, M. D., de la Fuente, M. A., Anton, I. M., Snapper, S., Fuhlbrigge, R. and Geha, R. S. 2006. WIP and WASP play complementary roles in T cell homing and chemotaxis to SDF-1alpha. Int. Immunol. 18:221.
-
(2006)
Int. Immunol.
, vol.18
, pp. 221
-
-
Gallego, M.D.1
de la Fuente, M.A.2
Anton, I.M.3
Snapper, S.4
Fuhlbrigge, R.5
Geha, R.S.6
-
12
-
-
0030816363
-
Defective actin reorganization and polymerization of Wiskott-Aldrich T cells in response to CD3-mediated stimulation
-
Gallego, M. D., Santamaría, M., Peña, J. and Molina, I. J. 1997. Defective actin reorganization and polymerization of Wiskott-Aldrich T cells in response to CD3-mediated stimulation. Blood 90:3089.
-
(1997)
Blood
, vol.90
, pp. 3089
-
-
Gallego, M.D.1
Santamaría, M.2
Peña, J.3
Molina, I.J.4
-
13
-
-
0032118427
-
Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation
-
Snapper, S. B., Rosen, F. S., Mizoguchi, E. et al. 1998. Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation. Immunity 9:81.
-
(1998)
Immunity
, vol.9
, pp. 81
-
-
Snapper, S.B.1
Rosen, F.S.2
Mizoguchi, E.3
-
14
-
-
0033230229
-
Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes
-
Zhang, J., Shehabeldin, A., da Cruz, L. A. et al. 1999. Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes. J. Exp. Med. 190:1329.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1329
-
-
Zhang, J.1
Shehabeldin, A.2
da Cruz, L.A.3
-
15
-
-
0034192223
-
Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosis
-
Lorenzi, R., Brickell, P. M., Katz, D. R., Kinnon, C. and Thrasher, A. J. 2000. Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosis. Blood 95:2943.
-
(2000)
Blood
, vol.95
, pp. 2943
-
-
Lorenzi, R.1
Brickell, P.M.2
Katz, D.R.3
Kinnon, C.4
Thrasher, A.J.5
-
16
-
-
77953497134
-
Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes
-
Westerberg, L. S., Meelu, P., Baptista, M. et al. 2010. Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes. J. Exp. Med. 207:1145.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1145
-
-
Westerberg, L.S.1
Meelu, P.2
Baptista, M.3
-
17
-
-
0034624753
-
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
-
Kim, A. S., Kakalis, L. T., Abdul-Manan, N., Liu, G. A. and Rosen, M. K. 2000. Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein. Nature 404:151.
-
(2000)
Nature
, vol.404
, pp. 151
-
-
Kim, A.S.1
Kakalis, L.T.2
Abdul-Manan, N.3
Liu, G.A.4
Rosen, M.K.5
-
18
-
-
0347915637
-
Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation
-
Badour, K., Zhang, J., Shi, F., Leng, Y., Collins, M. and Siminovitch, K. A. 2004. Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation. J. Exp. Med. 199:99.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 99
-
-
Badour, K.1
Zhang, J.2
Shi, F.3
Leng, Y.4
Collins, M.5
Siminovitch, K.A.6
-
19
-
-
0038392871
-
Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP
-
Torres, E. and Rosen, M. K. 2003. Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP. Mol. Cell 11:1215.
-
(2003)
Mol. Cell
, vol.11
, pp. 1215
-
-
Torres, E.1
Rosen, M.K.2
-
20
-
-
33645643086
-
Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP
-
Torres, E. and Rosen, M. K. 2006. Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP. J. Biol. Chem. 281:3513.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 3513
-
-
Torres, E.1
Rosen, M.K.2
-
21
-
-
1542304700
-
Focal adhesion kinase regulation of N-WASP subcellular localization and function
-
Wu, X., Suetsugu, S., Cooper, L. A., Takenawa, T. and Guan, J. L. 2004. Focal adhesion kinase regulation of N-WASP subcellular localization and function. J. Biol. Chem. 279:9565.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 9565
-
-
Wu, X.1
Suetsugu, S.2
Cooper, L.A.3
Takenawa, T.4
Guan, J.L.5
-
22
-
-
0034282711
-
Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold
-
Westphal, R. S., Soderling, S. H., Alto, N. M., Langeberg, L. K. and Scott, J. D. 2000. Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold. EMBO J. 19:4589.
-
(2000)
EMBO J.
, vol.19
, pp. 4589
-
-
Westphal, R.S.1
Soderling, S.H.2
Alto, N.M.3
Langeberg, L.K.4
Scott, J.D.5
-
23
-
-
0029815611
-
N-WASP, a novel actindepolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases
-
Miki, H., Miura, K. and Takenawa, T. 1996. N-WASP, a novel actindepolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases. EMBO J. 15:5326.
-
(1996)
EMBO J.
, vol.15
, pp. 5326
-
-
Miki, H.1
Miura, K.2
Takenawa, T.3
-
24
-
-
33745762947
-
Regulation of RNA-polymerase-II-dependent transcription by N-WASP and its nuclear-binding partners
-
Wu, X., Yoo, Y., Okuhama, N. N., Tucker, P. W., Liu, G. and Guan, J. L. 2006. Regulation of RNA-polymerase-II-dependent transcription by N-WASP and its nuclear-binding partners. Nat. Cell Biol. 8:756.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 756
-
-
Wu, X.1
Yoo, Y.2
Okuhama, N.N.3
Tucker, P.W.4
Liu, G.5
Guan, J.L.6
-
25
-
-
77955600265
-
Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome
-
Taylor, M. D., Sadhukhan, S., Kottangada, P. et al. 2010. Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome. Sci. Transl. Med. 2:37ra44.
-
(2010)
Sci. Transl. Med.
, vol.2
-
-
Taylor, M.D.1
Sadhukhan, S.2
Kottangada, P.3
-
26
-
-
0142211212
-
Translocation of N-WASP by nuclear localization and export signals into the nucleus modulates expression of HSP90
-
Suetsugu, S. and Takenawa, T. 2003. Translocation of N-WASP by nuclear localization and export signals into the nucleus modulates expression of HSP90. J. Biol. Chem. 278:42515.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 42515
-
-
Suetsugu, S.1
Takenawa, T.2
-
27
-
-
9944222181
-
WAVE1 intranuclear trafficking is essential for genomic and cytoskeletal dynamics during fertilization: cell-cycle-dependent shuttling between M-phase and interphase nuclei
-
Rawe, V. Y., Payne, C., Navara, C. and Schatten, G. 2004. WAVE1 intranuclear trafficking is essential for genomic and cytoskeletal dynamics during fertilization: cell-cycle-dependent shuttling between M-phase and interphase nuclei. Dev. Biol. 276:253.
-
(2004)
Dev. Biol.
, vol.276
, pp. 253
-
-
Rawe, V.Y.1
Payne, C.2
Navara, C.3
Schatten, G.4
-
28
-
-
0029984570
-
Nucleocytoplasmic transport
-
Görlich, D. and Mattaj, I. W. 1996. Nucleocytoplasmic transport. Science 271:1513.
-
(1996)
Science
, vol.271
, pp. 1513
-
-
Görlich, D.1
Mattaj, I.W.2
-
29
-
-
0037160142
-
Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation
-
Cory, G. O., Garg, R., Cramer, R., and Ridley, A. J. 2002. Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. J. Biol. Chem. 277:45115.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45115
-
-
Cory, G.O.1
Garg, R.2
Cramer, R.3
Ridley, A.J.4
-
30
-
-
77956163491
-
Regulation of WASp by phosphorylation: activation or other functions? Commun
-
Dovas, A. and Cox, D. 2010. Regulation of WASp by phosphorylation: activation or other functions? Commun. Integr. Biol. 3:101.
-
(2010)
Integr. Biol.
, vol.3
, pp. 101
-
-
Dovas, A.1
Cox, D.2
-
31
-
-
0034795423
-
N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility
-
Snapper, S. B., Takeshima, F., Antón, I. et al. 2001. N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility. Nat. Cell Biol. 3:897.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 897
-
-
Snapper, S.B.1
Takeshima, F.2
Antón, I.3
-
32
-
-
0037032415
-
PSF and p54(nrb)/NonO-multifunctional nuclear proteins
-
Shav-Tal, Y. and Zipori, D. 2002. PSF and p54(nrb)/NonO-multifunctional nuclear proteins. FEBS Lett. 531:109.
-
(2002)
FEBS Lett.
, vol.531
, pp. 109
-
-
Shav-Tal, Y.1
Zipori, D.2
-
33
-
-
2442435550
-
p54(nrb) associates with the 5' splice site within large transcription/splicing complexes
-
Kameoka, S., Duque, P. and Konarska, M. M. 2004. p54(nrb) associates with the 5' splice site within large transcription/splicing complexes. EMBO J. 23:1782.
-
(2004)
EMBO J.
, vol.23
, pp. 1782
-
-
Kameoka, S.1
Duque, P.2
Konarska, M.M.3
-
34
-
-
0031780282
-
Follicular large cell lymphoma with immunoblastic features in a child with Wiskott-Aldrich syndrome: an unusual immunodeficiency-related neoplasm not associated with Epstein-Barr virus
-
Kroft, S. H., Finn, W. G., Singleton, T. P., Ross, C. W., Sheldon, S. and Schnitzer, B. 1998. Follicular large cell lymphoma with immunoblastic features in a child with Wiskott-Aldrich syndrome: an unusual immunodeficiency-related neoplasm not associated with Epstein-Barr virus. Am. J. Clin. Pathol. 110:95.
-
(1998)
Am. J. Clin. Pathol.
, vol.110
, pp. 95
-
-
Kroft, S.H.1
Finn, W.G.2
Singleton, T.P.3
Ross, C.W.4
Sheldon, S.5
Schnitzer, B.6
-
35
-
-
1842857595
-
Development of diffuse large cell lymphoma from follicular lymphoma with multiple immunoglobulin heavy chain gene rearrangement occurring in a patient with Wiskott-Aldrich syndrome
-
Kawakami, K., Yamaguchi, M., Watanabe, Y. and Murata, T. 2002. Development of diffuse large cell lymphoma from follicular lymphoma with multiple immunoglobulin heavy chain gene rearrangement occurring in a patient with Wiskott-Aldrich syndrome. Int. J. Hematol. 76:196.
-
(2002)
Int. J. Hematol.
, vol.76
, pp. 196
-
-
Kawakami, K.1
Yamaguchi, M.2
Watanabe, Y.3
Murata, T.4
-
36
-
-
79955021525
-
Hodgkin's and non-Hodgkin's lymphomas occurring in two brothers with Wiskott-Aldrich syndrome and review of the literature
-
Du, S., Scuderi, R., Malicki, D. M., Willert, J., Bastian, J. and Weidner, N. 2011. Hodgkin's and non-Hodgkin's lymphomas occurring in two brothers with Wiskott-Aldrich syndrome and review of the literature. Pediatr. Dev. Pathol. 14:64.
-
(2011)
Pediatr. Dev. Pathol.
, vol.14
, pp. 64
-
-
Du, S.1
Scuderi, R.2
Malicki, D.M.3
Willert, J.4
Bastian, J.5
Weidner, N.6
-
37
-
-
34548447079
-
Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia
-
Moulding, D. A., Blundell, M. P., Spiller, D. G. et al. 2007. Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia. J. Exp. Med. 204:2213.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2213
-
-
Moulding, D.A.1
Blundell, M.P.2
Spiller, D.G.3
|