Enzymatic recovery of metabolites from seaweeds: Potential applications

Advances in Botanical Research

Volumn 71, Issue , 2014, Pages 279-320

  Hardouin, Kevin ^a,b   Bedoux, Gilles ^a   Burlot, Anne Sophie ^a   Nyvall Collén, Pi ^c   Bourgougnon, Nathalie ^a  

^a UNIVERSITÉ DE BRETAGNE SUD   (France)

^b ZA du Haut du Bois   (France)

^c Pôle Biotechnologique du Haut du Bois   (France)

Author keywords

Activities; Antioxidant; Antiviral; Enzymatic cracking; Enzymatic process; Feed; Fertilizers; Hydrolysates polysaccharides; Proteins

Indexed keywords

EID: 84901457963     PISSN: 00652296     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-408062-1.00010-X     Document Type: Chapter

References (131)

1. Ahn G., Hwang I., Park E., Kim J., Jeon Y.-J., Lee J., et al. Immunomodulatory effects of an enzymatic extract from Ecklonia cava on murine splenocytes. Marine Biotechnology 2008, 10(3):278-289.
2. Ahn C.B., Jeon Y.J., Kang D.S., Shin T.S., Jung B.M. Free radical scavenging activity of enzymatic extracts from a brown seaweed Scytosiphon lomentaria by electron spin resonance spectrometry. Food Research International 2004, 37(3):253-258.
3. Ahn G., Park E., Lee W.-W., Hyun J.-W., Lee K.-W., Shin T., et al. Enzymatic extract from Ecklonia cava induces the activation of lymphocytes by IL-2 production through the classical NF-κB pathway. Marine Biotechnology 2010, 13(1):66-73.
4. Alam F., Date A., Rasjidin R., Mobin S., Moria H., Baqui A. Biofuel from algae-is it a viable alternative?. Procedia Engineering 2012, 49:221-227.
5. Algae Industry Magazine Olmix opens algae biorefinery in Brittany 2013, Algae Industry Magazine. http://www.algaeindustrymagazine.com/olmix-opens-algae-biorefinery-brittany/.
6. Alves de Guimaraens M., Coutinho R. Temporal and spatial variation of Ulva spp. and water properties in the Cabo Frio upwelling region of Brazil. Aquatic Botany 2000, 66(2):101-114.
7. Amano H., Noda H. Proteins of protoplasts from red alga Porphyra yezoensis. Nippon Suisan Gakkaishi 1990, 56:1859-1864.
8. Amano H., Noda H. Proteins of protoplasts from several seaweeds. Nippon Suisan Gakkaishi 1992, 58:291-299.
9. Athukorala Y., Jung W.K., Vasanthan T., Jeon Y.J. An anticoagulative polysaccharide from an enzymatic hydrolysate of Ecklonia cava. Carbohydrate Polymers 2006, 66:184-191.
10. Athukorala Y., Lee K.W., Kim S.K., Jeon Y.J. Anticoagulant activity of marine green and brown algae collected from Jeju Island in Korea. Bioresource Technology 2007, 98:1711-1716.
11. Avila M., Seguel M. An overview of seaweed resources in Chile. Journal of Applied Phycology 1993, 5(2):133-139.
12. Barbeyron T., Lerat Y., Sassi J.-F., Le Panse S., Helbert W., Collen P.N. Persicivirga ulvanivorans sp. nov., a marine member of the family Flavobacteriaceae that degrades ulvan from green algae. International Journal of Systematic and Evolutionary Microbiology 2010, 61(8):1899-1905.
13. Bhakuni D.S., Rawat D.S. Bioactive marine natural products 2005, Springer, New York.
14. Bondu S., Deslandes E., Fabre M.S., Berthou C., Guangli Y. Carrageenan from Solieria chordalis (Gigartinales): structural analysis and immunological activities of the low molecular weight fractions. Carbohydrate Polymers 2010, 81(2):448-460.
15. Borines M.G., de Leon R.L., Cuello J.L. Bioethanol production from the macroalgae Sargassum spp. Bioresource Technolology 2013, 138:22-29.
16. Bouhlal R., Haslin C., Chermann J.C., Colliec-Jouault S., Sinquin C., Simon G., et al. Antiviral activities of sulfated polysaccharides isolated from Sphaerococcus coronopifolius (Rhodophytha, Gigartinales) and Boergeseniella thuyoides (Rhodophyta, Ceramiales). Marine Drugs 2011, 7:1187-1209.
17. Bouhlal R., Riadi H., Bourgougnon N. Antiviral activities of Morocco seaweeds extracts. African Journal of Biotechnology 2010, 9:7968-7975.
18. Bourgougnon N. Anti-HIV compounds from red seaweeds. Review. Bioorganisms and medicinal chemistry Letter 2003, Vol. 9. Recent Advances in Marine Biotechnology published by Science Publishers of Enfield, New Hampshire, USA and Plymouth, UK, 40 pp.
19. Bourgougnon N., Lahaye M., Chermann J.C., Kornprobst J.M. Composition and antiviral activities of sulfated polysaccharide from Schizymenia dubyi (Rhodophyta, Gigartinales). Bioorganic and Medicinal Chemistry Letter 1993, 3:1141-1146.
20. Bourgougnon N., Stiger-Pouvreau V. Chemodiversity and bioactivity within red and brown macroalgae along the french coasts, Metropole and Overseas Departments and Territories. Handbook of marine macroalgae 2011, 58-105. John Wiley & Sons, Ltd. S.-K. Kim (Ed.).
21. Briand, X., Cluzet, S., Dumas, B., Esquerre-Tugaye, M. T. & Salamagne, S. (October, 2005). WO. Patent No. 2005/094581. Use of ulvans as elicitors of mechanisms for nitrogen absorption and protein synthesis.
22. Buchholz C.M., Krause G., Buck B.H. Seaweed and man. Seaweed Biology 2012, Vol. 219:471-493. Springer Berlin Heidelberg, Berlin, Heidelberg. C. Wiencke, K. Bischof (Eds.).
23. Cardozo K.H.M., Guaratini T., Barros M.P., Falcão V.R., Tonon A.P., Lopes N.P., et al. Metabolites from algae with economical impact. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 2007, 146(1-2):60-78.
24. Casas G., Scrosati R., Piriz M.L. The invasive kelp Undaria pinnatifida (Phaeophyceae, Laminariales) reduces native seaweed diversity in Nuevo Gulf (Patagonia, Argentina). Biological Invasions 2004, 6(4):411-416.
25. Castro R., Piazzon M.C., Zarra I., Leiro J., Noya M., Lamas J. Stimulation of turbot phagocytes by Ulva rigida C. Agardh polysaccharides. Aquaculture 2006, 254:9-20.
26. Cebrian E., Ballesteros E. Temporal and spatial variability in shallow- and deep-water populations of the invasive Caulerpa racemosa var. cylindracea in the Western Mediterranean. Estuarine, Coastal and Shelf Science 2009, 83(4):469-474.
27. Charlier R.H., Morand P., Finkl C.W. How Brittany and Florida coasts cope with green tides. International Journal of Environmental Studies 2008, 65(2):191-208.
28. Charlier R.H., Morand P., Finkl C.W., Thys A. Green tides on the Brittany coasts. Environmental Research Engineering Management 2007, 3(41):52-59.
29. Choi S.P., Nguyen M.T., Sim S.J. Enzymatic pretreatment of Chlamydomonas reinhardtii biomass for ethanol production. Bioresource Technology 2010, 101(14):5330-5336.
30. Chopin T., Robinson S.M.C., Troell M., Neori A., Buschmann A.H., Fang J. Multitrophic integration for sustainable marine aquaculture. Encyclopedia of ecology 2008, 2463-2475. Academic Press, Oxford. S.E. Jørgensen, B.D. Fath (Eds.).
31. Chopin T., Sawhney M. Seaweeds and their Mariculture. Encyclopedia of ocean Sciences 2009, 317-326. Academic Press, Oxford. 2nd ed. J.H. Steele (Ed.).
32. Cian R.E., Martínez-Augustin O., Drago S.R. Bioactive properties of peptides obtained by enzymatic hydrolysis from protein byproducts of Porphyra columbina. Food Research International 2012, 49(1):364-372.
33. Coat G., Dion P., Noailles M.-C., De Reviers B., Fontaine J.-M., Berger-Perrot Y., et al. Ulva armoricana (Ulvales, Chlorophyta) from the coasts of Brittany (France). II. Nuclear rDNA ITS sequence analysis. European Journal of Phycology 1998, 33(1):81-86.
34. Correc G., Hehemann J.H., Czjzek M., Helbert W. Structural analysis of the degradation products of porphyran digested by Zobellia galactanivorans β-porphyranase A. Carbohydrate Polymers 2011, 83(1):277-283.
35. Courtois J. Oligosaccharides from land plants and algae: production and applications in therapeutics and biotechnology. Current Opinion in Microbiology 2009, 12(3):261-273.
36. Damonte E.B., Matulewicz M.C., Cerezo A.S. Sulfated seaweed polysaccharides as antiviral agents. Current Medicinal Chemistry 2004, 11:2399-2419.
37. De Casabianca M.L., Barthelemy N., Serrano O., Sfriso A. Growth rate of Ulva rigida in different Mediterranean eutrophicated sites. Bioresource Technology 2002, 82(1):27-31.
38. Demais, H., Brendle, J., Jaber, M., & Laza, A. L. (September 2006a). FR. Patent No. 2006/2882997. Exfoliating an intercalated clay, useful in e.g. animal/human feeds, plastification, surface coatings and in nanocomposite, comprises preparing intercalated clay from clay and intercalating compound and lyophilizing in presence of water.
39. Demais, H., Brendle, J., Le Deit, H., Laza A. L., Lurton, L., Brault, D. (March 2006b). WO. Pantent No. 2006/030075. (Interspersed clay).
40. Denis C., Morançais M., Li M., Deniaud E., Gaudin P., Wielgosz-Collin G., et al. Study of the chemical composition of edible red macroalgae Grateloupia turuturu from Brittany (France). Food Chemistry 2010, 119(3):913-917.
41. Douglas-Westwood Marine industries global market analysis 2005.
42. Ducreux, P. (2010). Le risque d'intoxication aiguë par l'hydrogène sulfuré (H2S) chez les professionnels chargés du ramassage, du transport et du traitement des "algues vertes". Unpublished DiplÔme Médecine Agricole. Institut National de Médecine Agricole, Tours, France. Retrieved from http://www.fichier-pdf.fr/2011/01/07/memoire-algues-vertes-dr-ducreux/memoire-algues-vertes-dr-ducreux.pdf.
43. Duke C.S., Litaker R.W., Ramus J. Seasonal variation in RuBPcase activity and N allocation in the chlorophyte seaweeds Ulva curvata (kutz.) de toni and Codium decorticatum (Woodw.) Howe. Journal of Experimental Marine Biology and Ecology 1987, 112(2):145-164.
44. Dumay J., Clément N., Morançais M., Fleurence J. Optimization of hydrolysis conditions of Palmaria palmata to enhance R-phycoerythrin extraction. Bioresource Technology 2013, 131:21-27.
45. D'Amours O., Scheibling R.E. Effect of wave exposure on morphology, attachment strength and survival of the invasive green alga Codium fragile ssp. tomentosoides. Journal of Experimental Marine Biology and Ecology 2007, 351:129-142.
46. El Boutachfaiti R., Delattre C., Petit E., El Gadda M., Courtois B., Michaud P., et al. Improved isolation of glucuronan from algae and the production of glucuronic acids oligosaccharides using a glucuronan lyase. Carbohydrate Research 2009, 344:1670-1675.
47. El Modafar C., Elgadda M., El Boutachfaiti R., Abouraicha E., Zehhar N., Petit E., Courtois J. Induction of natural defence accompanied by salicylic acid-dependant systemic acquired resistance in tomato seedlings in response to bioelicitors isolated from green algae. Scientia Horticulturae 2012, 138:55-63.
48. Engelen A., Santos R. Which demographic traits determine population growth in the invasive brown seaweed Sargassum muticum?. Journal of Ecology 2009, 97(4):675-684.
49. Estevez J.M., Ciancia M., Cerezo A.S. The system of sulfated galactans from the red seaweed Gymnogongrus torulosus (Phyllophoraceae, Rhodophyta): location and structural analysis. Carbohydrate Polymers 2008, 73(4):594-605.
50. Fleurence J. The enzymatic degradation of algal cell walls: a useful approach for improving the protein accessibility?. Journal of Applied Phycology 1999, 11:313-314.
51. Fleurence J. Seaweed proteins: biochemical, nutritional aspects and potential uses. Trends in Food Science & Technology 1999, 10(1):25-28.
52. Fleurence J., Massiani L., Guyader O., Mabeau S. Use of enzymatic cell wall degradation for improvement of protein extraction from Chondrus crispus, Gracilaria verrucosa and Palmaria palmata. Journal of Applied Phycology 1995, 7(4):393-397.
53. Fleurence J., Morançais M., Dumay J., Decottignies P., Turpin V., Munier M., et al. What are the prospects for using seaweed in human nutrition and for marine animals raised through aquaculture?. Trends in Food Science & Technology 2012, 27:57-61.
54. Floc'h J.Y., Deslandes E., Le Gall Y. Evidence for vegetative propagation of the carrageenophyte Solieria chordalis (Solieriaceae, Rhodophyceae) on the coast of Brittany (France) and in culture. Botanica Marina 1987, 30:315-321.
55. Food and Agriculture Organization World aquaculture 2010 2011, Food and Agriculture Organization of the United Nations, Rome.
56. Hardouin K., Burlot A.S., Umami A., Nyvall-Collen P., Bedoux G., Bourgougnon N. Enzyme-assisted extraction of bioactive metabolites from seaweeds. Cell biology, physiology and biochemistry. Journées de la Société Phycologique de France December 2013, Station Biologique de Roscoff, France, in press. M. Czjzek (Chair) (Ed.).
57. Hardouin K., Burlot A.-S., Umami A., Tanniou A., Stiger-Pouvreau V., Widowati I., Bedoux G., Bourgougnon N. Biochemical and antiviral activities of enzymatic hydrolysates from different invasive French seaweeds. Journal of Applied Phycology 2013, in press. http://dx.doi.org/10/1007/s10811-013-0201-6.
58. Harnedy P.A., FitzGerald R.J. Extraction of protein from the macroalga Palmaria palmata. Food Science and Technology 2011, 51:375-382.
59. Harnedy P.A., FitzGerald R.J. Extraction of protein from the macroalga Palmaria palmata. LWT - Food Science and Technology 2013, 51(1):375-382.
60. Harshvardhan K., Mishra A., Jha B. Purification and characterization of cellulase from a marine Bacillus sp. H1666: a potential agent for single step saccharification of seaweed biomass. Journal of Molecular Catalysis B: Enzymatic 2013, 93:51-56.
61. Helbert, W., and Nyvall-Collen, P. (December 2011). WO. Patent No. 2011/157966. Ulvan lyase, method for manufacturing same, and uses thereof.
62. Heo S.-J., Jeon Y.-J., Lee J., Kim H.T., Lee K.-W. Antioxidant effect of enzymatic hydrolysate from a Kelp, Ecklonia cava. Algae 2003, 18(4):341-348.
63. Heo S., Park E., Lee K., Jeon Y. Antioxidant activities of enzymatic extracts from brown seaweeds. Bioresource Technology 2005, 96(14):1613-1623.
64. Holdt S.L., Kraan S. Bioactive compounds in seaweed: functional food applications and legislation. Journal of Applied Phycology 2011, 23(3):543-597.
65. Hu C., Li D., Chen C., Ge J., Muller-Karger F.E., Liu J., et al. On the recurrent Ulva prolifera blooms in the Yellow Sea and East China Sea. Journal of Geophysical Research 2010, 115(C5).
66. Ioannou E., Roussis V. Natural products from seaweeds 2009, Springer Science, Berlin.
67. Jaulneau V., Lafitte C., Jacquet C., Fournier S., Salamagne S., Briand X., et al. Ulvan, a sulfated polysaccharide from green algae, activates plant immunity through the jasmonic acid signaling pathway. Journal of Biomedicine and Biotechnology 2010, (525291):11. 10.1155/2010/525291.
68. Jeon Y.J., Wijesinghe W.A.J.P., Kim S.K. Enzyme-assisted extraction and recovery of bioactive components from seaweeds. Handbook of Marine macroalgae 2011, 221-228. John Wiley & Sons, Ltd. S.K. Kim (Ed.).
69. Jung K.A., Lim S.-R., Kim Y., Park J.M. Potentials of macroalgae as feedstocks for biorefinery. Bioresource Technology 2013, 135:182-190.
70. Kaimoussi A., Mouzdahir A., Saih A. Seasonal variations of metal concentrations (Cd, Cu, Fe, Mn and Zn) in algae fucus spiralis from the coast of el Jadida City (Morocco). Water Quality Research Journal of Canada 2005, 40(1):102-110.
71. Kang S.M., Kim K.N., Lee S.H., Ahn G., Cha S.H., Kim A.D., et al. Anti-inflammatory activity of polysaccharide purified from AMG-assistant extract of Ecklonia cava in LPS-stimulated RAW 264.7 macrophages. Carbohydrate Polymers 2011, 85(1):80-85.
72. Kapraun D.F. Red algal polysaccharide industry: economics and research status at the turn of the century. Sixteenth international seaweed Symposium 1999, 7-14. Springer.
73. Kirkman H., Kendrick G.A. Ecological significance and commercial harvesting of drifting and beach-cast macro-algae and seagrasses in Australia: a review. Journal of Applied Phycology 1997, 9(4):311-326.
74. Kloareg B., Quatrano R.S. Structure of the cell walls of marine algae and ecophysiological functions of the matrix polysaccharides. Oceanographic Marine Biological Annual Review 1988, 26:259-315.
75. Kornprobst J.M. Substances naturelles d'origine marine: Chimiodiversité - Pharmacodiversité - Biotechnologies 2005, Editions Tec & Doc.
76. Lahaye M., Brunel M., Bonnin E. Fine chemical structure analysis of oligosaccharides produced by an ulvan-lyase degradation of the water-soluble cell-wall polysaccharides from Ulva sp. (Ulvales, Chlorophyta). Carbohydrate Research 1997, 304(3-4):325-333.
77. Lahaye M., Jegou D., Buleon A. Chemical characteristics of insoluble glucans from the cell wall of the marine green alga Ulva lactuca (L.) Thuret. Carbohydrate Research 1994, 262(1):115-125.
78. Lahaye M., Robic A. Structure and functional properties of ulvan, a polysaccharide from Green seaweeds. Biomacromolecules 2007, 8(6):1765-1774.
79. Lahaye M., Vigouroux J. Liquefaction of dulse (Palmaria palmata (L.) Kuntze) by a commercial enzyme preparation and purified endo-β-1,4-d-xylanase. Journal of Applied Phycology 1992, 4:329-337.
80. Lapointe B.E., Bedford B.J. Ecology and nutrition of invasive Caulerpa brachypus f. parvifolia blooms on coral reefs off southeast Florida, U.S.A. Harmful Algae 2010, 9(1):1-12.
81. Le Lann K., Connan S., Stiger-Pouvreau V. Phenology, TPC and size-fractioning phenolics variability in temperate Sargassaceae (Phaeophyceae, Fucales) from Western Brittany: native versus introduced species. Marine Environmental Research 2012, 80:1-11.
82. Lundqvist L.C.E., Jam M., Barbeyron T., Czjzek M., Sandström C. Substrate specificity of the recombinant alginate lyase from the marine bacteria Pseudomonas alginovora. Carbohydrate Research 2012, 352:44-50.
83. Marinho-Soriano E., Fonseca P.C., Carneiro M.A.A., Moreira W.S.C. Seasonal variation in the chemical composition of two tropical seaweeds. Bioresource Technology 2006, 97(18):2402-2406.
84. Mathieson A.C., Dawes C.J., Pederson J., Gladych R.A., Carlton J.T. The Asian red seaweed Grateloupia turuturu (Rhodophyta) invades the Gulf of Maine. Biological Invasions 2007, 10(7):985-988.
85. McHugh D.J., Food and Agriculture Organization of the United Nations A guide to the seaweed industry 2003, Food and Agriculture Organization of the United Nations, Rome.
86. Menshova R.V., Ermakova S.P., Anastyuk S.D., Isakov V.V., Dubrovskaya Y.V., Kusaykin M.I., et al. Structure, enzymatic transformation and anticancer activity of branched high molecular weight laminaran from brown alga Eisenia bicyclis. Carbohydrate Polymers 2014, 99:101-109.
87. Mercier L., Lafitte C., Borderies G., Briand X., Esquerré-Tugayé M.-T., Fournier J. The algal polysaccharide carrageenans can act as an elicitor of plant defense. New Phytologist 2001, 149(1):43-51.
88. Moroney N.C., O'Grady M.N., O'Doherty J.V., Kerry J.P. Addition of seaweed (Laminaria digitata) extracts containing laminarin and fucoidan to porcine diets: Influence on the quality and shelf-life of fresh pork. Meat Science 2012, 92(4):423-429.
89. Naylor R.L., Goldburg R.J., Primavera J.H., Kautsky N., Beveridge M.C., Clay J., et al. Effect of aquaculture on world fish supplies. Nature 2000, 405(6790):1017-1024.
90. Nilsang S., Lertsiri S., Suphantharika M., Assavanig A. Optimization of enzymatic hydrolysis of fish soluble concentrate by commercial proteases. Journal of Food Engineering 2005, 70(4):571-578.
91. Okuda K., Oka K., Onda A., Kajiyoshi K., Hiraoka M., Yanagisawa K. Hydrothermal fractional pretreatment of sea algae and its enhanced enzymatic hydrolysis. Journal of Chemical Technology & Biotechnology 2008, 83(6):836-841.
92. Park P.J., Shahidi F., Jeon Y.J. Antioxidant activities of enzymatic extracts from an edible seaweed sargassum horneri using ESR spectrometry. Journal of Food Lipids 2004, 11(1):15-27.
93. Paull R.E., Chen N.J. Postharvest handling and storage of the edible red seaweed Gracilaria. Postharvest Biology and Technology 2008, 48(2):302-308.
94. Peña-Farfal C., Moreda-Piñeiro A., Bermejo-Barrera A., Bermejo-Barrera P., Pinochet-Cancino H., de Gregori-Henríquez I. Speeding up enzymatic hydrolysis procedures for the multi-element determination in edible seaweed. Analytica Chimica Acta 2005, 548(1-2):183-191.
95. Pereira R., Yarish C. Mass production of marine macroalgae. Encyclopedia of ecology 2008, 2236-2247. Academic Press, Oxford. S.E. Jørgensen, B.D. Fath (Eds.).
96. Plouguerné E., Le Lann K., Connan S., Jechoux G., Deslandes E., Stiger-Pouvreau V. Spatial and seasonal variations in density, maturity, length and phenolic content of the invasive brown macroalga Sargassum muticum along the coast of Western Brittany (France). Aquatic Botany 2006, 85:337-344.
97. Popper Z.A., Michel G., Hervé C., Domozych D.S., Willats W.G.T., Tuohy M.G., et al. Evolution and diversity of plant cell walls: from algae to flowering plants. Annual Review of Plant Biology 2011, 62:567-590.
98. Rindi F., Guiry M.D. Composition and spatial variability of terrestrial algal assemblages occurring at the bases of urban walls in Europe. Phycologia 2004, 43(3):225-235.
99. Robic A., Sassi J.-F., Lahaye M. Impact of stabilization treatments of the green seaweed Ulva rotundata (Chlorophyta) on the extraction yield, the physico-chemical and rheological properties of ulvan. Carbohydrate Polymers 2008, 74(3):344-352.
100. Romarís-Hortas V., Bermejo-Barrera P., Moreda-Piñeiro A. Ultrasound-assisted enzymatic hydrolysis for iodinated amino acid extraction from edible seaweed before reversed-phase high performance liquid chromatography-inductively coupled plasma-mass spectrometry. Journal of Chromatography a 2013, 1309:33-40.
101. Romero J.B., Villanueva R.D., Montaño M.N.E. Stability of agar in the seaweed Gracilaria eucheumatoides (Gracilariales, Rhodophyta) during postharvest storage. Bioresource Technology 2008, 99(17):8151-8155.
102. Rosenberg C., Ramus J. Ecological growth strategies in the seaweeds Gracilaria foliifera (Rhodophyceae) and Ulva sp. (Chlorophyceae): soluble nitrogen and reserve carbohydrates. Marine Biology 1982, 66(3):251-259.
103. Ruiz G.M., Fofonoff P.W., Carlton J.T., Wonham M.J., Hines A.H. Invasion of coastal marine communities in North America: apparent patterns, processes, and biases. Annual Review of Ecology and Systematics 2000, 481-531.
104. Samarakoon K., Jeon Y.J. Bio-functionnalities of proteins derived from marine algae. Food Research International 2012, 48:948-960.
105. Schiel D.R., Thompson G.A. Demography and population biology of the invasive kelp Undaria pinnatifida on shallow reefs in southern New Zealand. Journal of Experimental Marine Biology and Ecology 2012, 434-435:25-33.
106. Sfriso A., Facca C. Annual growth and environmental relationships of the invasive species Sargassum muticum and Undaria pinnatifida in the lagoon of Venice. Estuarine, Coastal and Shelf Science 2013, 129:162-172.
107. Siriwardhana N., Kim K.N., Lee K.W., Kim S.H., Ha J.H., Song C.B. Optimisation of hydrophilic antioxidant extraction from Hizikia fusiformis by integrating treatments of enzymes, heat and pH control. International Journal of Food Science And Technology 2008, 43:587-596.
108. Smetacek V., Zingone A. Green and golden seaweed tides on the rise. Nature 2013, 504(7478):84-88.
109. Stagnol D., Renaud M., Davoult D. Effects of commercial harvesting of intertidal macroalgae on ecosystem biodiversity and functioning. Estuarine, Coastal and Shelf Science 2013, 130:99-110.
110. Steneck R.S., Graham M.H., Bourque B.J., Corbett D., Erlandson J.M., Estes J.A., et al. Kelp forest ecosystems: biodiversity, stability, resilience and future. Environmental Conservation 2003, 29(04).
111. Stengel D.B., Connan S., Popper Z.A. Algal chemodiversity and bioactivity: sources of natural variability and implications for commercial application. Biotechnology Advances 2011, 29(5):483-501.
112. Stiger V., Deslandes E., Payri C.E. Phenolic contents of two brown algae, Turbinaria ornata and Sargassum mangarevense on Tahiti (French Polynesia): interspecific, ontogenic and spatio-temporal variations. Botanica Marina 2004, 47:402-409.
113. Stiger V., Payri C.E. Spatial and seasonal variations in the biological characteristics of two invasive brown algae, Turbinaria ornata (Turner) J. Agardh and Sargassum mangarevense (Grunow) Setchell (Sargassaceae, Fucales) spreading on the reefs of Tahiti (French Polynesia). Botanica Marina 1999, 42(3):295-306.
114. Suryanarayan, S., Nori, S. S., Kumar, S., Vadassery, N., Balendiran, S., Sayash Kumar, S. (June 2013). WO. Patent No. 2013/050860. Process of production of renewable chemicals and biofuels from seaweeds.
115. Tavennec M. La gestion d'une problématique algale dans un secteur hautement touristique, la presqu'île de Rhuys 2009, Rapport de master 2, Université de Nantes.
116. Tchorbanov B., Bozhkova M. Enzymatic hydrolysis of cell proteins in green algae Chlorella and Scenedesmus after extraction with organic solvents. Enzyme and Microbial Technology 1988, 10(4):233-238.
117. Titlyanov E.A., Titlyanova T.V. Seaweed cultivation: methods and problems. Russian Journal of Marine Biology 2010, 36(4):227-242.
118. Trivedi N., Gupta V., Reddy C.R.K., Jha B. Enzymatic hydrolysis and production of bioethanol from common macrophytic green alga Ulva fasciata Delile. Bioresource Technology 2013, 150:106-112.
119. Villares R., Carballeira A. Seasonal variation in the concentrations of nutrients in two green macroalgae and nutrient levels in sediments in the Rías Baixas (NW Spain). Estuarine, Coastal and Shelf Science 2003, 58(4):887-900.
120. Villares R., Puente X., Carballeira A. Seasonal variation and background levels of heavy metals in two green seaweeds. Environmental Pollution 2002, 119(1):79-90.
121. Vincent V. Les Algues Marines et leurs emplois agricoles, alimentaires, industriels, etc 1924.
122. Vo T.S., Ngo D.H., Ta Q.V., Kim S.K. Marine organisms as a therapeutic source against herpes simplex virus infection. European Journal of Pharmaceutical Science 2011, 44:11-20.
123. Wang T., Jónsdóttir R., Kristinsson H.G., Hreggvidsson G.O., Jónsson J.Ó., Thorkelsson G., et al. Enzyme-enhanced extraction of antioxidant ingredients from red algae Palmaria palmata. Lwt-food Science and Technology 2010, 43:1387-1393.
124. Wang X., Liu X., Wang G. Two stage hydrolysis of invasive algal feedstock for ethanol fermentation. Journal Integrative Plant Biology 2011, 53:246-253.
125. White L.F., Shurin J.B. Density dependent effects of an exotic marine macroalga on native community diversity. Journal of Experimental Marine Biology and Ecology 2011, 405(1-2):111-119.
126. Wijesekara I., Pangestuti R., Kim S.K. Biological activities and potential health benefits of sulfated polysaccharides derived from marine algae. Carbohydrate Polymers 2011, 84:14-21.
127. Wijesinghe W.A.J.P., Athukorala Y., Jeon Y.J. Effect of anticoagulative sulfated polysaccharide purified from enzyme-assistant extract of a brown seaweed Ecklonia cava on Wistar rats. Carbohydrate Polymers 2011, 86(2):917-921.
128. Wijesinghe W.A.J.P., Jeon Y.-J. Enzyme-assistant extraction (EAE) of bioactive components: a useful approach for recovery of industrially important metabolites from seaweeds: a review. Fitoterapia 2012, 83(1):6-12.
129. Williams S.L., Smith J.E. A global review of the distribution, taxonomy, and impacts of introduced seaweeds. Annual Review of Ecology, Evolution, and Systematics 2007, 38(1):327-359.
130. Yoon, Y. S., Goh, G. H., Song, J. H., Oh, S. H., Kang, S. Y., Park, C. H. (February 24, 2010). WO. Patent No. 2010/098585 A2. Method for producing biofuels via hydrolysis of seaweed extract using heterogeneous catalyst.
131. Zhang J.H., Huo Y.Z., Zhang Z.L., Yu K.F., He Q., Zhang L.H., et al. Variations of morphology and photosynthetic performances of Ulva prolifera during the whole green tide blooming process in the Yellow Sea. Marine Environmental Research 2013, 92:35-42.