Temozolomide induces autophagy via ATM-AMPK-ULK1 pathways in glioma

Molecular Medicine Reports

Volumn 10, Issue 1, 2014, Pages 411-416

  Zou, Yuhui ^a   Wang, Qiong ^a   Li, Bingling ^a   Xie, Bing ^a   Wang, Weimin ^a  

^a GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND   (China)

Author keywords

Adenosine monophosphate activated protein kinase; Ataxia telangiectasia mutated; Autophagy; Glioma; Temozolomide

Indexed keywords

2 MORPHOLINO 6 (1 THIANTHRENYL) 4 PYRANONE; ADENYLATE KINASE; ATM PROTEIN; HISTONE H2AX; PHOSPHOTRANSFERASE; TEMOZOLOMIDE; ULK1 PROTEIN; UNCLASSIFIED DRUG; 2-MORPHOLIN-4-YL-6-THIANTHREN-1-YL-PYRAN-4-ONE; ALKYLATING AGENT; DACARBAZINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAP1LC3B PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; MORPHOLINE DERIVATIVE; PROTEIN SERINE THREONINE KINASE; PYRONE DERIVATIVE; SIGNAL PEPTIDE; ULK1 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL VACUOLE; CELL VIABILITY; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVATION; GLIOBLASTOMA; GLIOMA; HUMAN; HUMAN CELL; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; BRAIN TUMOR; DRUG EFFECTS; METABOLISM; PATHOLOGY; TOXICITY; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; ANTINEOPLASTIC AGENTS, ALKYLATING; ATAXIA TELANGIECTASIA MUTATED PROTEINS; AUTOPHAGY; BRAIN NEOPLASMS; CELL LINE, TUMOR; DACARBAZINE; GLIOMA; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MORPHOLINES; PROTEIN-SERINE-THREONINE KINASES; PYRONES; SIGNAL TRANSDUCTION;

EID: 84901457597     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2151     Document Type: Article

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